Clinical trials
Cancer (With or Without Metastasis) clinical trials
Below are recruiting cancer (with or without metastasis) clinical trials, each written for real people, not researchers. We’re tracking 13,052 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06466434Recruiting
Prebiotic diet to boost immunotherapy for melanoma
This trial tests whether a special prebiotic diet can help your body's bacteria (microbiome) better respond to standard immunotherapy for advanced melanoma that cannot be removed by surgery. If you are starting your first immunotherapy, you may be able to join.
Houston, TexasAges 18 years+ - NCT06461910RecruitingPhase 2
Immunotherapy, thymalfasin, and chemo before surgery for stomach cancer
This trial is testing a combination of three medicines—an immunotherapy (anti-PD-1), an immune booster (thymalfasin), and a chemotherapy regimen (SOX)—given before surgery to shrink stage III stomach or gastroesophageal junction cancer and improve outcomes.
Nanjing, JiangsuAges 18–75 - NCT06468215Recruiting
Fertility-sparing treatment for early stage 2 endometrial cancer
This study tests a way to treat early-stage endometrial cancer without removing the uterus, so you can still have a chance to carry a pregnancy. It’s for women under 45 with a grade 2 tumor that hasn’t grown into the womb muscle.
Beijing, Beijing MunicipalityAges Up to 45 years - NCT06477419RecruitingPhase 2
Sacituzumab govitecan for mesothelioma after prior treatment
This study tests a drug called sacituzumab govitecan (a targeted therapy that delivers chemotherapy directly to cancer cells) for people with mesothelioma that has already been treated with other therapies. The goal is to see if the drug can shrink tumors and help control the disease.
Basking Ridge, New JerseyAges 18 years+ - NCT06476067Recruiting
Predicting early esophageal cancer return after surgery
This trial uses stored tumor tissue to try to predict if esophageal cancer will come back early after surgery. It is for people who had surgery only (no chemo or radiation) and have been followed for at least 2 years.
Nagoya, Aichi-kenAges 20 years+ - NCT06466395RecruitingPhase 1
Hyper-CVAD plus venetoclax for relapsed pediatric leukemia
This trial tests a combination of chemotherapy drugs (hyper-CVAD) plus a targeted pill called venetoclax for children and young adults with a type of leukemia that has returned or not responded to treatment. The goal is to see if this combo can help control the leukemia.
Houston, TexasAges 2–21 - NCT06469606Recruiting
Mammogram texture study for women having mastectomy
This study looks at mammogram images of women who are scheduled to have one or both breasts removed (mastectomy). Researchers want to learn about patterns in breast tissue to improve future breast cancer screening.
TampereAges 18 years+ - NCT06462092RecruitingPhase 1/Phase 2
Sacituzumab Govitecan and Spinal Chemo for Breast Cancer Spread to Spinal Fluid
This trial tests a combination of a targeted antibody-drug (sacituzumab govitecan) and chemotherapy given into the spinal fluid. It is for people with HER2-negative breast cancer that has spread to the membranes around the brain and spinal cord (leptomeningeal metastases). The goal is to see if this treatment can help control the cancer in the central nervous system.
Huizhou, GuangdongAges 18–75 - NCT06470971RecruitingPhase 2
Siltuximab to prevent severe side effects during immunotherapy rechallenge
This trial tests if siltuximab can prevent severe immune-related side effects when patients restart immunotherapy (anti-PD-1/PD-L1) after previous severe side effects. It aims to make rechallenge safer for people with advanced cancer.
Columbus, OhioAges 18 years+ - NCT06468618Recruiting
Sleep and stress program for kids getting stem cell transplant
This study tests a program to help children ages 9–17 who are getting a stem cell transplant at Boston Children's Hospital. It aims to improve sleep and reduce stress for both the child and their family.
Boston, MassachusettsAges 9–17 - NCT06463262Recruiting
Personalized markers for chordoma before surgery and radiation
This trial tests whether analyzing blood and tumor samples before and after radiation and surgery can help find personalized markers for chordoma. It is for patients with chordoma of the skull base, spine, or sacrum who will receive radiation before surgery.
Baltimore, MarylandAges 18 years+ - NCT06462521Enrolling by invitation
Comparing two ways to remove large polyps during a colonoscopy
This study compares two methods for removing larger polyps (flat growths) found during a colonoscopy. It tests if one technique works as well or better than the other for people with certain types of polyps.
Indianapolis, IndianaAges 18 years+ - NCT06462937Recruiting
Digital exercise program for recent spondyloarthritis diagnosis
This trial tests a digital exercise program for people newly diagnosed with axial spondyloarthritis (a type of arthritis that affects the spine and joints). If you have active disease, you may join to see if exercise helps manage symptoms.
OsloAges 18 years+ - NCT05942885Recruiting
Hypnosis for calming anxiety in lymphoma patients
This trial studies whether hypnosis can help reduce anxiety. It is meant for adults with certain types of lymphoma who are newly told their diagnosis and have anxiety symptoms.
Lyon, Pierre-BéniteAges 18 years+ - NCT06450106RecruitingPhase 1
STM-416p injection during prostate removal surgery
This trial tests an injection called STM-416p given during prostate removal surgery to see if it can help prevent prostate cancer from coming back. It may be an option for men with intermediate to high-risk prostate cancer who are already planning to have their prostate removed.
Tucson, ArizonaAges 18 years+ - NCT06458712RecruitingPhase 1
Testing a new drug for advanced cancers with gene changes
This study tests a new oral drug, DSB2455, for people with advanced breast, prostate, ovarian, or pancreatic cancers that have certain gene changes. It aims to see if the drug is safe and whether it helps shrink or control the cancer.
Sacramento, CaliforniaAges 18 years+ - NCT06445972RecruitingPhase 1/Phase 2
Testing combination therapies for advanced stomach or esophageal cancer
This study tests new drug combinations for people with advanced stomach or esophageal cancer that worsened after first treatment. It aims to find better options for those whose tumors lack HER2.
Tucson, ArizonaAges 18 years+ - NCT06455384Recruiting
Studying a digital tool for genetic testing services
This trial tests a new online tool called the Genetics Navigator, which helps people access genetic testing services more easily. If you or your child have been referred for genetic testing at Mount Sinai Hospital or SickKids in Toronto, this study may help you manage the process online.
Toronto, OntarioAges 18 years+ - NCT06448013RecruitingPhase 1
Ziftomenib with chemo for pediatric AML
This trial tests a new drug, ziftomenib, combined with two standard chemotherapies (venetoclax and gemtuzumab) for children and young adults with acute myeloid leukemia (AML) that has come back or not responded to treatment. It looks for specific genetic changes in the leukemia cells.
Houston, TexasAges 3–21 - NCT06440616Recruiting
Spectral CT scans for lung cancer detection
This trial is testing a new way to look at CT scans (called spectral imaging) to see if it can better detect lung cancer in people who are suspected of having it. If you are being referred for lung cancer testing, this study may help doctors get clearer information from your scans.
Herlev, Capital RegionAges Any age - NCT06445959RecruitingPhase 1/Phase 2
Decitabine, Venetoclax, and Olutasidenib for IDH1-Mutated Blood Cancers
This trial combines three drugs—decitabine, venetoclax, and a targeted therapy (olutasidenib)—to treat acute myeloid leukemia (AML) or high-risk myelodysplastic syndrome (MDS) that has come back or is not responding to treatment. It may also be an option for people newly diagnosed with AML who cannot receive intense chemotherapy.
Miami, FloridaAges 18 years+ - NCT06450873RecruitingPhase 2
Turkey tail mushroom before breast cancer surgery
This trial tests whether taking a turkey tail mushroom supplement before breast cancer surgery can help the immune system fight the cancer. It is for post-menopausal women with a common type of breast cancer (ER-positive, HER2-negative) that is growing at a moderate or faster rate (Ki-67 score of 10% or more).
Scottsdale, ArizonaAges 18 years+ - NCT06458439RecruitingPhase 2
Epcoritamab with CAR T cells for large B-cell lymphoma
This trial tests a combination of two immune therapies—epcoritamab (a bispecific antibody) and CAR T cells—for people with large B-cell lymphoma whose cancer didn't respond to first treatment. The goal is to see if this combination works better than CAR T cells alone.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06448351Recruiting
Changing nicotine in e-cigarettes to reduce harm
This study tests how changing the amount of nicotine in e-cigarettes affects people's behavior. It looks at two groups: young adults who already vape and older adult smokers who want to try vaping, to see if different nicotine levels can help reduce smoking or make vaping safer.
Columbus, OhioAges 21–65
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Common questions
- Are there clinical trials for cancer (with or without metastasis)?
- Yes. Clin2 currently lists 13,052 recruiting cancer (with or without metastasis) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer (with or without metastasis) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer (with or without metastasis) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3)
- Non Small Cell Lung Cancer
- Liver Metastasis Colon Cancer
- Gastric Cancer, Gastroesophageal Junction Cancer
- Lung Cancer Non-Small Cell Cancer (NSCLC)
- Colorectal Cancer Liver Metastasis
- Breast Cancer (Triple Negative Breast Cancer (TNBC))
- Leptomeningeal Metastasis of Breast Cancer
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.