Clinical trials · Baltimore, MD
Cancer clinical trials in Baltimore
We’re tracking 801 recruiting cancer studies with a site in or near Baltimore — including Phase 1, Phase 1/Phase 2, Phase 2 and Phase 2/Phase 3 studies, each written for real people, not researchers.
Recruiting studies near Baltimore
- NCT06606990RecruitingPhase 1
Testing the drug CX-5461 for advanced solid tumors
This trial tests a new drug called CX-5461 (also known as pidnarulex) in people whose cancer has spread and hasn't been helped by standard treatments. It looks at how your body responds to the drug, which may target cancers with specific DNA repair problems.
Bethesda, MarylandAges 18 years+ - NCT04235764Recruiting
Testing a new bladder-tumor surgery tool for removed tissue
This trial studies a redesigned surgical instrument used during bladder tumor removal, to see if it can improve how the removed tissue samples are collected. It may help future patients by supporting better study of bladder tissue during cancer care.
Bethesda, MarylandAges 18–120 - NCT01441089Recruiting
Donate blood for genetic testing in an NIH research study
This study collects blood from people already in an NIH (National Institutes of Health) clinical research program to run genetic tests. It may help researchers understand cancer and related inherited conditions by studying DNA changes.
Bethesda, MarylandAges 3 years+ - NCT01313442Recruiting
Give blood and tumor samples for gastrointestinal cancer research
This trial collects blood and tumor tissue from adults with cancer to help researchers study gastrointestinal cancers. If you’re eligible, your participation mainly involves donating samples for research purposes.
Bethesda, MarylandAges 18 years+ - NCT02595957Recruiting
Study about how people understand genetic test results
This trial studies what people and families think and understand about genetic test results, especially when results suggest a higher risk for disease. It may also include interviews and follow-up, and in some cases additional family testing if it fits the study’s goals.
Bethesda, MarylandAges 1 month–105 years - NCT07444723RecruitingPhase 2/Phase 3
New imaging to find parathyroid tumors before surgery
This study tests two advanced imaging techniques (PET/MR and PET/CT) to find overactive parathyroid glands or tumors that need surgery. Participants get a special scan before surgery to help surgeons locate the problem more accurately.
Bethesda, MarylandAges 18–100 - NCT04074135RecruitingPhase 2
Study of pancreatic tumors in people with VHL
This trial studies the natural course and management of pancreatic neuroendocrine tumors in people with von Hippel–Lindau (VHL) disease. It may help doctors better predict how these pancreatic findings change over time and how to manage them.
Bethesda, MarylandAges 12 years+ - NCT06176989RecruitingPhase 2
Enasidenib for IDH2-mutated sinonasal and skull base tumors
This trial tests an oral targeted therapy called enasidenib for people with rare head and neck cancers that have an IDH2 gene mutation. The goal is to see if this drug can shrink or slow the growth of these tumors.
Bethesda, MarylandAges 18–120 - NCT06161545RecruitingPhase 2
Immunotherapy before surgery for head and neck cancer
This trial tests a combination of two immunotherapy drugs (pembrolizumab and N-803) with or without special immune cells (PD-L1 t-haNK cells) before surgery for head and neck cancer. The goal is to see if this treatment can shrink the cancer or improve the outcome after surgery.
Bethesda, MarylandAges 18–120 - NCT06161532RecruitingPhase 2
Sacituzumab govitecan with or without atezolizumab for rare GU cancers
This trial is testing a drug called sacituzumab govitecan, sometimes combined with atezolizumab (an immunotherapy), for rare cancers of the bladder, urinary tract, kidney, or penis. The goal is to see if these treatments work well for people whose cancers have not responded to other options.
Bethesda, MarylandAges 18–120 - NCT06161519RecruitingPhase 1/Phase 2
PLX038 for brain tumors with MYC or MYCN changes
This study tests a new drug called PLX038 for people with brain or spinal cord tumors that have certain genetic changes (MYC or MYCN) or have come back after treatment. The drug is given as an infusion and targets tumor cells. The study aims to see if the drug is safe and effective for different types of these tumors.
Bethesda, MarylandAges 18–120 - NCT06171750RecruitingPhase 1
Study of ANK-101 for advanced solid tumors
This trial tests a new drug, ANK-101, injected directly into tumors to help fight advanced solid tumors that have spread or can't be treated with standard therapies. It may be an option if you have a tumor that can be reached for injection.
Bethesda, MarylandAges 18 years+ - NCT00923026Enrolling by invitation
Follow-up for adults previously treated in NCI surgery studies
This study asks people age 18+ who were previously treated on certain NCI Surgery Branch (NCI-SB) studies to come back for follow-up. It helps researchers understand how patients do over time after those earlier treatments, including some gene therapy studies.
Bethesda, MarylandAges 18 years+ - NCT06157151RecruitingPhase 2
New drug plus pembrolizumab for advanced cervical cancer
This trial tests a new experimental drug, PRGN-2009, combined with the immunotherapy pembrolizumab (Keytruda) for people with HPV-related cervical cancer that has come back or spread. It is for those who have already tried pembrolizumab and are looking for another option.
Bethesda, MarylandAges 18 years+ - NCT06096870RecruitingPhase 2
Enzalutamide with a new drug for prostate cancer that is active on PET scan
This trial tests a combination of enzalutamide (a hormone blocker) and an investigational antibody-drug (PDS01ADC) in men whose prostate cancer has come back after initial treatment, but has not yet spread extensively. It does not involve standard hormone therapy that lowers testosterone.
Bethesda, MarylandAges 18–120 - NCT03841617RecruitingPhase 2
Measure radiation in thyroid cancer using a special PET-CT scan
This trial tests how much radiation a specialized whole-body PET/CT scan delivers in patients with differentiated thyroid cancer. It may help doctors better plan treatment for cancer that persists, returns, or has spread—especially when radioactive iodine (RAI) may or may not work.
Bethesda, MarylandAges 18–90 - NCT05960773RecruitingPhase 2
Oral medication for early mesothelioma in BAP1 gene carriers
This study tests an oral medication called decitabine/cedazuridine (INQOVI) that may help delay or prevent progression in people with early-stage mesothelioma who carry a BAP1 mutation. The treatment is given as a pill and aims to reactivate genes that may help control cancer growth.
Bethesda, MarylandAges 18–120 - NCT04755205Recruiting
Natural history study of olfactory neuroblastoma
This study follows people with olfactory neuroblastoma over time to better understand how the disease behaves and changes. It may help future patients by improving doctors’ knowledge, even if it does not test a new treatment.
Bethesda, MarylandAges 3–120 - NCT04706663Recruiting
Genomics-guided treatment for people with prostate cancer
This trial uses genetic test results from your prostate cancer to guide treatment choices. It may help find therapies that better match the specific gene changes in your cancer.
Bethesda, MarylandAges 18–120 - NCT02621021RecruitingPhase 2
Immune cell therapy for advanced melanoma
This trial tests a treatment that uses your own immune cells, called tumor-infiltrating lymphocytes (TILs), to fight melanoma. Some participants also get a drug called pembrolizumab. The goal is to see if this approach can shrink tumors.
Bethesda, MarylandAges 18–72 - NCT02830724RecruitingPhase 1/Phase 2
CAR T therapy using blood immune cells for CD70 cancers
This trial tests a personalized immune-cell treatment (CAR T) built from your own blood lymphocytes. It targets cancers that show a marker called CD70, aiming to slow or stop the cancer when other treatments didn’t work.
Bethesda, MarylandAges 18–72 - NCT02821806Recruiting
Donate blood cells to help grow immune cells for therapy
This is a study that recruits healthy adults to donate a type of blood cell (PBMCs) so researchers can grow T cells for future adoptive cell therapy. It tests a process for collecting and expanding immune cells; participation mainly involves blood donation and health screening.
Bethesda, MarylandAges 18–120 - NCT07667400RecruitingPhase 1/Phase 2
Docetaxel plus SX-682 for advanced head and neck or prostate cancer
This trial studies a combination of the chemotherapy drug docetaxel and an investigational drug called SX-682 for people with certain advanced head and neck cancers or prostate cancer. The goal is to see if the combination is safe and effective.
Bethesda, MarylandAges 18–120 - NCT07499128Enrolling by invitation
Continuous temperature monitoring for cytokine release syndrome
This study tests a wearable device that continuously monitors your body temperature to detect cytokine release syndrome, a possible side effect of certain immunotherapies. The goal is to catch it early so you can get treatment faster.
Bethesda, MarylandAges 18–120
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Cancer trials in other cities
Where these studies are running near Baltimore
Institutions with a site for the recruiting cancer studies listed above.
- National Institutes of Health Clinical Center · 21 studies
- National Cancer Institute
- National Cancer Institute Developmental Therapeutics Clinic
- National Institute of Health
What taking part in a cancer study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting cancer studies in Maryland.
Common questions
- Are there cancer clinical trials near Baltimore?
- Yes. We're currently tracking 801 recruiting cancer studies with a site near Baltimore, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a cancer study near Baltimore?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Baltimore to take part?
- Not necessarily. These studies have a site near Baltimore, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a cancer trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New cancer studies open near Baltimore regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.