Clinical trials
Cardiac Disease clinical trials
Below are recruiting cardiac disease clinical trials, each written for real people, not researchers. We’re tracking 313 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07063147Recruiting
Heart ultrasound for stable chest pain management
This study uses a heart ultrasound (TTE) to help doctors better manage stable chest pain. If you have chest pain that may be from a blocked artery but haven't had a heart attack or heart procedures before, this trial could help improve your care.
TianjinAges 18 years+ - NCT05946174Recruiting
Personalized frailty program for older people with heart frailty
This trial aims to adjust frailty-support activities for people who are physically vulnerable because of heart problems. It may help by creating a plan tailored to your needs, while carefully checking health issues that could make participation unsafe.
SingaporeAges 21–100 - NCT05585125RecruitingPhase 4
Testing an informed approach for older adults with HFpEF
This study looks at an “informed” approach to help manage HFpEF (a type of heart failure) in people age 65 and older. It checks whether a structured plan and monitoring are practical and safe for you over time.
New York, New YorkAges 65 years+ - NCT07351825Recruiting
Heart MRI study for people with ischemic heart disease
This study uses heart MRI scans to find markers that predict outcomes in people with ischemic heart disease, including those who have had a heart attack. It may help doctors better understand your condition and guide future care.
Beijing, Beijing MunicipalityAges Any age - NCT06579807Recruiting
Cardiac rehab for coronary artery disease
This study tests if a cardiac rehabilitation program helps people with coronary artery disease. You can join if you are between 40 and 70, have heart disease (or are a healthy volunteer), and do not have other health issues like heart failure or smoking.
Rio de Janeiro, Rio de JaneiroAges 40–70 - NCT05493605Recruiting
MRI study of heart involvement in Wilson disease
This study looks at whether Wilson disease affects the heart, using MRI scans (and possibly contrast dye). Your results may help doctors better understand cardiac (heart) involvement and how it progresses in Wilson disease.
ParisAges 18 years+ - NCT05139797Recruiting
AI-guided heart ultrasound screening for suspected amyloidosis
This study tests whether an artificial-intelligence system can help decide who should get a special heart workup for a rare disease called cardiac amyloidosis. If you have signs that make doctors suspect this, the AI-guided ultrasound screening may help find it sooner.
Los Angeles, CaliforniaAges 18 years+ - NCT05208567Recruiting
Testing heart ultrasound in older adults with weak heart pumping
This trial uses a heart ultrasound test to find people who may have weak heart pumping function, especially in a multi-ethnic community. It may help improve how doctors detect this condition earlier using ultrasound images.
LondonAges 65 years+ - NCT05812755RecruitingPhase 4
Study drug effects on blood vessels and organs in heart surgery
This Phase 4 trial studies vericiguat-like stimulation (a type of medicine that affects blood-vessel signaling) around the time of planned open-heart surgery. It aims to see whether this can change blood-vessel “reactivity” and reduce injury to organs during and after surgery.
Nashville, TennesseeAges 18 years+ - NCT05632432Recruiting
Heart tissue grafts to help the heart after surgery
This trial tests whether transplanting tiny heart “micrografts” from the left heart chamber area can improve heart function after cardiac surgery. It is meant for people with weakened heart pumping and heart failure symptoms despite medicine.
Helsinki, UusimaaAges 18–75 - NCT02381301Recruiting
Blood and heart CT scan tests for heart blood-flow markers
This study looks at whether certain lab “biomarkers” and a heart CT scan can help understand heart blood flow in people getting routine coronary CT angiography (CCTA). It may be useful for improving how doctors assess heart health from scan and blood results.
Maastricht, LimburgAges 18 years+ - NCT07871188Recruiting
Blood pressure swings and recovery after heart bypass surgery
This study looks at how changes in blood pressure during heart bypass surgery relate to how quickly the body clears lactic acid afterwards, which is a sign of recovery. It may help doctors understand recovery patterns after surgery.
GaziantepAges 18–80 - NCT07588230Recruiting
Nerve Block for Minimally Invasive Heart Valve Surgery Pain
This study tests a targeted nerve block (pain-numbing injection) to help manage pain after minimally invasive heart valve surgery. Researchers want to see if this technique reduces pain and the need for opioid medications during recovery.
Diyarbakır, Outside of the USAges 18–75 - NCT04808401Recruiting
Testing how different oxygen levels affect surgery outcomes
This trial studies whether giving higher or lower oxygen during general anesthesia changes heart and lung outcomes after planned (non-emergency) non-heart surgery. It may help doctors choose safer oxygen settings during surgery for people at higher risk for heart problems.
BernAges 18 years+ - NCT05373498Recruiting
Registry for children’s heart emergencies after resuscitation
This trial is a registry that collects information about children (under 18) who have congenital heart problems and need resuscitation with chest compressions. It helps doctors understand these emergencies and may improve future care for similar patients.
Leipzig, SaxonyAges Up to 18 years - NCT06258681Recruiting
Breathing exercise device for recovery after heart surgery
This trial tests a new breathing exercise device designed to help your lungs recover after heart surgery. It may make your breathing easier and speed up your return to daily activities.
Istanbul, IstanbulAges 40–65 - NCT07315997Recruiting
Heart health study for people with rheumatoid arthritis
This study looks at whether calcium in the heart arteries and a blood test (troponin) can help predict heart disease risk in people with rheumatoid arthritis. It may help doctors better prevent heart attacks and strokes.
Boston, MassachusettsAges 35–79 - NCT06906432Recruiting
Brain-Heart Injury After Brain Bleed Study
This study looks at how a brain bleed can affect the heart. Researchers hope to understand the link between brain and heart injury to help improve care for people who have had a brain bleed.
Beijing, Beijing MunicipalityAges 18–80 - NCT07172620Recruiting
Heart bypass surgery without clamping the aorta
This study tests a special technique for heart bypass surgery that avoids clamping the aorta. It may help people with hardened arteries in the aorta who need bypass surgery but are not good candidates for standard clamping.
Beijing, Beijing MunicipalityAges Any age - NCT06800781Recruiting
Chest tube duration to prevent afib after heart surgery
This trial tests if leaving a chest tube in a little longer after heart surgery can lower the chance of developing atrial fibrillation (an irregular heart rhythm). It's for people having certain planned heart surgeries who have not had this rhythm problem before.
LundAges 18 years+ - NCT06690151Recruiting
Babies with heart defects and development support
This study looks at how a serious heart condition before birth may affect a baby's brain development. It follows babies and their parents to better understand and support these children as they grow.
Nantes, Loire AtlantiqueAges Any age - NCT06262126Recruiting
Virtual reality for non-cardiac chest pain
This study tests whether virtual reality can help people who have chest pain that is not caused by the heart. You will use a VR headset to see if it reduces your symptoms.
Jacksonville, FloridaAges 18 years+ - NCT04164173Recruiting
Breathing therapies after heart surgery for lung overinflation
This study looks at breathing (respiratory) therapies to help after certain heart surgeries that can cause the lungs to feel overly inflated. If you’re eligible, you may receive and be assessed for how well these breathing treatments work during your recovery.
Dallas, TexasAges 18–80 - NCT04299828Recruiting
Study of inflammation activity during complex heart surgery
This study measures how active white blood cells and inflammation are during complex heart surgery using a heart-lung machine. It may help doctors better understand what triggers inflammation during surgery and how to improve care.
Boston, MassachusettsAges Any age
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Common questions
- Are there clinical trials for cardiac disease?
- Yes. Clin2 currently lists 313 recruiting cardiac disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cardiac disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cardiac disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.