Clinical trials
Cardiac Failure clinical trials
Below are recruiting cardiac failure clinical trials, each written for real people, not researchers. We’re tracking 191 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03793257Recruiting
ECMO patient registry for adults in Australia and New Zealand
This is a research registry for adults who need a breathing and/or heart support machine called ECMO while in the hospital. It collects information to better understand who receives ECMO and how patients do over time.
Canberra, Australian Capital TerritoryAges 18 years+ - NCT05179616Recruiting
Study of TriClip treatment for severe leaky tricuspid valve
This study follows adults with a severely leaky tricuspid heart valve who still have symptoms despite medication. It looks at outcomes after a procedure called TriClip, which helps reduce valve leakage.
PforzheimAges 18 years+ - NCT05593679Recruiting
Registry study for heart PYP scans in possible ATTR amyloidosis
This study collects information from adults who have been diagnosed with, or are being checked for, ATTR amyloidosis (a condition where abnormal protein builds up in the body) using a heart PYP scan. Your participation may help doctors better understand how these scans relate to diagnosis and follow-up over time.
New Taipei CityAges 20 years+ - NCT04983823Recruiting
Study aims to improve long-term heart effects after COVID
This trial looks at how persistent heart-related changes after a past COVID infection may be affected by study treatments. It mainly seeks people who are stable enough for follow-up visits and heart imaging, and who are not already on the specific heart medications required.
Melbourne, VictoriaAges 50–85 - NCT06332391Recruiting
Paced heart rate increase for heart conditioning
This trial tests whether a special pacing pattern can strengthen your heart's pumping ability. You may qualify if you have heart failure with a low ejection fraction and already have a pacemaker or defibrillator with an atrial lead.
Iowa City, IowaAges 18–120 - NCT07527715Recruiting
Heart MRI Study for Dilated Heart Muscle Disease
This research uses cardiac MRI scans and patient data to better predict outcomes in people with dilated cardiomyopathy—a condition where the heart's main pumping chamber becomes enlarged and weakened. Participating could help doctors improve how they care for similar patients in the future.
Jinan, ShandongAges 18 years+ - NCT04262830Recruiting
Heart scans to predict future heart failure after chemotherapy
This trial uses detailed heart imaging (a special MRI scan) to see how chemotherapy may have affected your heart and to predict who could develop heart failure later. If you qualify, it may help your care team better monitor your heart health over time.
San Diego, CaliforniaAges 13–39 - NCT07515508Recruiting
Understanding heart failure patterns in hospitalized patients
This study investigates different types of acute heart failure in hospitalized patients to better understand their condition and improve treatment. Researchers will use multiple imaging and testing methods to create a detailed picture of each patient's heart failure.
Bad KrozingenAges 18 years+ - NCT06678841Recruiting
Pacing therapy for heart failure with preserved pumping ability
This study tests a new pacing approach for people with a specific type of heart failure (HFpEF) to see if it can improve symptoms and quality of life. It involves a pacemaker-like device that adjusts heart rate based on your needs.
Phoenix, ArizonaAges 40 years+ - NCT06080074RecruitingPhase 2
Emergency heart-lung machine study for children with severe heart failure
This study tests a specific heart-lung machine called Cardiohelp to help children with severe heart failure. It looks at how well the machine works and whether a blood thinner (either heparin or bivalirudin) is safer and more effective.
Palo Alto, CaliforniaAges birth–16 years - NCT07164911Recruiting
Heart failure rehab: who benefits most?
This study looks at what helps people with heart failure get the most out of a cardiac rehab program. It aims to find out which patients improve the most after completing phase II cardiac rehab.
CorbieAges 40–75 - NCT05696652Recruiting
Exercise training study for people with heart failure
This study looks for blood and other markers that can explain how people with heart failure respond to exercise training. It may help researchers better tailor exercise or treatment plans for heart failure in the future.
Stanford, CaliforniaAges 18–89 - NCT00733590Recruiting
Study after ICD generator replacement for heart attack patients
This study follows people who had a prior heart attack and later received a replacement ICD (a device that helps prevent sudden dangerous heart rhythms). It is observational, meaning it mainly looks at outcomes and device-related information rather than testing a new drug.
Washington D.C., District of ColumbiaAges 18–85 - NCT05873543Recruiting
Smartphone-based exercise program for heart failure recovery
This trial tests whether a hybrid heart-rehabilitation program that uses a smartphone helps people with heart failure feel better and safely exercise. If you’re eligible, you’ll likely get guided exercise training with help from a phone app.
TaipeiAges 18–80 - NCT06573242Recruiting
Home heart rehab for heart failure and caregivers
This trial tests a home-based heart rehab program for people with heart failure and their caregivers. It aims to help you manage your condition with support at home, instead of traveling to a center.
Herlev, copenhagenAges 18 years+ - NCT05564689Recruiting
Tests coronary blood flow in heart failure patients with CRT
This study measures how well blood flows in the heart (coronary flow) in people with heart failure with reduced pumping strength and a specific heart rhythm problem called left bundle branch block. It focuses on people who already have a cardiac resynchronization therapy (CRT) device and have stable treatment, to see how coronary flow relates to their heart condition.
AalborgAges 18 years+ - NCT06183437RecruitingPhase 4
Can I stop heart meds after cancer therapy?
This trial tests whether it is safe to stop taking heart failure medications in people who developed heart weakness after cancer treatment but whose heart function has since recovered. It aims to see if stopping these drugs leads to any worsening of heart health.
Los Angeles, CaliforniaAges 18 years+ - NCT05064709Recruiting
Test device for heart failure symptoms in some patients
This study tests whether a heart-related device called CCM can improve symptoms and daily function in people with heart failure and a moderately reduced pumping strength. It may help if you’ve had recent heart-failure-related hospital care or urgent treatment and your heart and overall health fit the study limits.
Birmingham, AlabamaAges 18 years+ - NCT06540521Recruiting
Heart device holter study for LBBAP patients
This study uses a special wearable device to record your heart's electrical signals. It is for people who have a pacemaker or CRT-P with a specific type of lead (LBBAP) and wants to check how well the therapy is working.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06427304Recruiting
Heart scan study for amyloid protein in older adults
This trial is testing older adults with heart failure to see if a heart condition called cardiac amyloidosis (a buildup of abnormal protein in the heart) is present. If you are 80 or older, have been in the hospital for heart failure in the past year, and have a thickened heart wall, you may be able to join.
Paris, IIe-de-FranceAges 80 years+ - NCT06885164Recruiting
Remote heart monitoring for heart failure patients
This trial tests whether remote monitoring of heart function can help manage heart failure. It may be an option if you have symptoms like shortness of breath or fatigue (NYHA class II or higher) and are between 18 and 90 years old.
Aalborg, DenmarkAges 18–90 - NCT05465031RecruitingPhase 4
Testing heart-protection medicine during breast cancer treatment
This trial tests sacubitril/valsartan to help prevent heart weakness (cardiotoxicity) caused by breast cancer treatments like anthracyclines and/or anti-HER2 drugs. If you qualify, you may be offered this heart-protection medicine while your cancer is treated.
Opole, Opole VoivodeshipAges 18 years+ - NCT06750536Recruiting
Safety study of a new lung support device for small children
This trial is testing a new device (MiniLung Petite Kit) for babies and young children with severe lung or heart failure. The device helps oxygenate the blood and remove carbon dioxide, giving the lungs and heart a chance to rest and heal.
Bonn, North Rhine-WestphaliaAges Up to 8 months - NCT06349941RecruitingPhase 3
Heart failure rehab from home using video visits
This study tests whether a home-based cardiac rehab program using video visits and a smartphone app can help people with heart failure recover and feel better. It may be a good option if you have been hospitalized for heart failure recently and want to take part in rehab from home.
Dallas, TexasAges 18 years+
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Common questions
- Are there clinical trials for cardiac failure?
- Yes. Clin2 currently lists 191 recruiting cardiac failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cardiac failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cardiac failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.