Clinical trials
Cardiac Valve Disease clinical trials
Below are recruiting cardiac valve disease clinical trials, each written for real people, not researchers. We’re tracking 131 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07516444Recruiting
Tricuspid valve replacement using a new catheter device
This trial tests a new device that replaces a leaky tricuspid valve (a heart valve) without open-heart surgery. If your tricuspid valve isn't working well and medicines haven't helped enough, this procedure might improve your heart function and symptoms.
Minneapolis, MinnesotaAges 18 years+ - NCT05595226Recruiting
Ultrasound-guided mitral valve repair to improve heart outcomes
This study looks at whether using a special heart ultrasound during surgery (called RT3D-TEE) can lead to better results for people having mitral valve repair. It’s mainly for certain types of chronic mitral valve leakage.
Beijing, Beijing MunicipalityAges 18–80 - NCT04073420Recruiting
Cardiac surgery registry to track Medtronic device outcomes
This registry collects real-world information from people who have had—or plan to have—an eligible Medtronic cardiac surgery device. It aims to better understand how these treatments do over time and help guide future care.
Marietta, GeorgiaAges Any age - NCT06001073Recruiting
Heart and brain disease health prediction study
This study uses advanced health data to predict how heart and brain conditions may progress. It aims to help doctors provide better care for people with these diseases.
Xi'an, ShaanxiAges 3–80 - NCT06001489Recruiting
Virtual reality for anxiety before heart surgery
This trial tests whether watching a 360-degree virtual reality video can help reduce anxiety before heart surgery. If you are waiting for elective heart surgery and are at least 18 years old, you may be able to participate.
Amsterdam, North HollandAges 18 years+ - NCT06066970Recruiting
Studying heart markers after valve surgery
This trial uses a special MRI and blood tests to see how heart muscle is affected after aortic or mitral valve surgery. It may help doctors better understand and monitor heart recovery.
Freiburg im Breisgau, Baden-WurttembergAges 18 years+ - NCT06144125RecruitingPhase 4
Blood management trial for heart surgery patients
This trial compares two treatments (prothrombin complex concentrate and fresh frozen plasma) for managing bleeding during heart surgery. It aims to find which approach works better and is safer for patients.
Seoul, SeoulAges 20–75 - NCT06595992Recruiting
Observing moderate aortic valve disease over time
This study follows people with moderate aortic valve disease to learn how their condition changes. It does not test a new treatment but will help doctors better understand the disease.
Hangzhou, ZhejiangAges 18 years+ - NCT06660524RecruitingPhase 4
Calcium-phosphorus therapy for heart valve disease
This trial tests a treatment to lower high calcium and phosphorus levels in your blood, which may slow down calcium buildup in heart valves. It may help people with kidney problems who have valve disease.
Beijing, Beijing MunicipalityAges 50 years+ - NCT07097740Recruiting
Study of a new polymer heart valve for mitral or aortic replacement
This study tests a new type of prosthetic heart valve made from a special polymer material. It is for adults who need surgical replacement of either the mitral or aortic valve.
Shanghai, Shanghai MunicipalityAges 50 years+ - NCT07267117Recruiting
Heart valve disease progression and outcomes study
This study is following people with heart valve disease (leaky or narrowed valves) to understand how the disease changes over time and what problems it may cause. It does not test a new treatment, but helps doctors learn more about valve disease progression.
Fuzhou, FujianAges 18 years+ - NCT03142152Recruiting
Mitral valve implant for heart failure with leaky mitral valve
This trial tests whether a device called the Carillon Mitral Contour System can help people with heart failure caused by a mild-to-moderate leaky mitral valve. You’d be compared against a control group, and the goal is to improve heart failure symptoms and outcomes.
Gilbert, ArizonaAges 18 years+ - NCT07511673Recruiting
Dental screening before heart valve surgery
This trial tests whether a dental checkup before heart valve surgery can improve recovery and prevent complications. If you are scheduled for a heart valve procedure, you may be able to join.
GothenburgAges 18 years+ - NCT07662317Recruiting
Heart surgery recovery registry study
This study collects information from people having heart surgery to help doctors learn more about recovery. If you are scheduled for surgery during the study period, you may be able to join.
Hangzhou, ZhejiangAges Any age - NCT05979870Enrolling by invitation
AI-enhanced heart MRI for valve disease
This study uses artificial intelligence to improve MRI scans for people with aortic or pulmonary valve disease who are scheduled for valve surgery or a non-surgical valve procedure. It aims to help doctors better assess heart function before treatment.
Gothenburg, GothenburgAges 1 week–18 years - NCT05714293Enrolling by invitation
CT measurements after surgical aortic valve replacement
This study uses a CT scan (with contrast dye) to measure the coronary artery openings after people have a new aortic valve placed surgically. It aims to see how to best plan or understand coronary blood flow after the surgery.
RomaAges 18–80 - NCT06126367Recruiting
Study on lipoprotein(a) and clot breakdown in heart disease
This trial looks at how a type of fat in the blood called lipoprotein(a) and your body's ability to break down clots affect heart disease or heart valve disease. It is for people who are already taking certain cholesterol-lowering medicines or have severe aortic valve narrowing from calcium buildup.
StevenageAges 18 years+ - NCT05635227Recruiting
Medications during heart surgery to help control breathing and circulation
This study looks at whether giving dexamethasone and olanzapine during certain heart surgeries can improve how blood flow and ventilation (breathing support) are managed. It’s meant to see if these medicines help the body handle heart-lung bypass more safely.
CopenhagenAges 18 years+ - NCT01653223Recruiting
Simvastatin to protect the heart during heart surgery
This trial looks at whether simvastatin (a cholesterol medicine) can help protect the heart during cardiac surgery. You might be invited if you’re having surgery for certain, non-complex heart conditions, but not if you have some specific related health problems.
Guangzhou, GuangdongAges 18 years+ - NCT07617844Recruiting
Advanced MRI imaging for heart disease diagnosis
This study uses advanced magnetic resonance imaging (MRI) scans to better understand and diagnose heart disease. If you have suspected or confirmed heart problems, this trial may help doctors get clearer pictures of your heart muscle and tissue to figure out what's causing your symptoms.
Hangzhou, ZhejiangAges 18 years+ - NCT07008911Recruiting
Fitness program for heart rehabilitation
This trial tests if a popular fitness app can help people recover from heart problems. You would do workouts at home and see if they improve your health and recovery.
Aurora, ColoradoAges 18 years+ - NCT05002543Recruiting
Real-world study of heart valve repair devices for multiple valves
This study checks how well and how safely CORCYM valve devices work in real-world patients with heart valve problems in the aortic, mitral, and/or tricuspid positions. It may help doctors understand expected outcomes outside of tightly controlled research settings.
Indianapolis, IndianaAges Any age - NCT05506293Recruiting
Registry study for sealing leaking heart valve devices
This is a study that collects information from people who are having a minimally invasive procedure to close a leak around a heart valve replacement device. It may help doctors better understand how well this procedure works and what outcomes to expect.
CharleroiAges 16–110 - NCT06336213Recruiting
Using a blood test to guide antibiotics in aorta surgery
This trial checks if a blood test called presepsin can help doctors decide when to use antibiotics in patients having surgery on the chest's main artery (the thoracic aorta). It is for people with an aneurysm or tear in that artery.
Moscow, MoscowAges 18–75
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Common questions
- Are there clinical trials for cardiac valve disease?
- Yes. Clin2 currently lists 131 recruiting cardiac valve disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cardiac valve disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cardiac valve disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.