Clinical trials
Cardiomyopathies clinical trials
Below are recruiting cardiomyopathies clinical trials, each written for real people, not researchers. We’re tracking 322 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05568069Recruiting
Study of defibrillator implants for non-ischemic weak heart
This study looks at whether implantable defibrillators can reduce dangerous heart rhythms in people with non-ischemic cardiomyopathy (heart weakness not caused by blocked heart arteries), a heart scar, and very low pumping strength despite best treatment. It compares different approaches to choosing which patients should receive these devices.
High Wycombe, BuckinghamshireAges 18 years+ - NCT05632432Recruiting
Heart tissue grafts to help the heart after surgery
This trial tests whether transplanting tiny heart “micrografts” from the left heart chamber area can improve heart function after cardiac surgery. It is meant for people with weakened heart pumping and heart failure symptoms despite medicine.
Helsinki, UusimaaAges 18–75 - NCT05650658Recruiting
Compare two heart pacing options in people with weak heart function
This trial compares two types of “left-side” heart pacing to see which one works better in people with weak heart pumping. It may help guide the best pacing choice for improving heart function and symptoms.
Gilbert, ArizonaAges 18 years+ - NCT05651919Recruiting
Blood test study to understand diabetic heart weakness
This study measures immune cells from your blood to find markers (biomarkers) that may explain or predict diabetic cardiomyopathy, a type of heart condition linked to diabetes. You may benefit mainly by being closely monitored and contributing to research that could improve future diagnosis or risk tracking.
BronAges 40–85 - NCT05658965Recruiting
EEG monitoring after early heart surgery in infants
This study looks at whether early brain-wave testing (EEG) around the time of heart surgery in very young babies can predict later learning and development issues. It may help doctors identify children who need extra support sooner.
Lille, Hauts-de-FranceAges 1 day–1 year - NCT05718128RecruitingPhase 4
Study of taking heart muscle samples from the inside
This trial studies patients who need an endocardial myocardial biopsy, meaning a small heart muscle sample taken from inside the heart. It’s meant for people with heart problems whose cause is not clearly known and may help doctors learn more about what’s going on.
Hangzhou, ZhejiangAges 18–80 - NCT05797857Recruiting
Exercise program for transthyretin heart amyloidosis
This trial studies whether a structured exercise training program is safe and helpful for people with transthyretin (ATTR) cardiac amyloidosis. It may help improve fitness and daily functioning, and it may also compare groups for specific eligibility needs.
Boston, MassachusettsAges 60–90 - NCT05836259RecruitingPhase 1/Phase 2
TN-201 for heart symptoms from MYBPC3 heart disease
This early trial tests TN-201 to see how safe it is and how well it works to reduce symptoms in adults with MYBPC3-related hypertrophic cardiomyopathy. It’s designed to learn safe dosing, and you may be eligible if you have specific genetic heart changes and ongoing symptoms.
La Jolla, CaliforniaAges 18–75 - NCT05868616Recruiting
Checking heart resynchronization timing with a noninvasive test
This trial evaluates a noninvasive way to assess who should get Cardiac Resynchronization Therapy (CRT), and to check results after implantation. If you fit the heart rhythm and heart pump criteria, the approach may help confirm whether CRT is appropriate for you.
OsloAges 18–80 - NCT05921279Recruiting
Study heart events in people with breast cancer
This study looks at what heart-related side effects happen in women with breast cancer who are planned to receive chemotherapy. It may help doctors better understand and monitor these risks during treatment.
GalwayAges 18–90 - NCT05939700Recruiting
Watching infants after mavacamten use in pregnancy
This study follows people who took mavacamten during pregnancy or breastfeeding to better understand infant outcomes. It may help doctors and families know what to expect and improve safety guidance.
Wilmington, North CarolinaAges 15 years+ - NCT05942729Recruiting
Checking heart disease diagnosis using echo images and health data
This study looks at how well heart ultrasound (echocardiography) images and clinical information can be used to diagnose cardiac conditions. If you have a clear ultrasound study already or can get one with good image quality, your information may help improve diagnostic accuracy.
Pierre-BéniteAges 18 years+ - NCT05946772RecruitingPhase 2
Cyclosporine for Takotsubo heart weakness in the first day
This trial studies whether cyclosporine, an immune-related medicine, can improve outcomes in Takotsubo syndrome (a temporary heart muscle problem). It aims to start treatment very soon after a heart catheter test to help the heart recover.
Bad NauheimAges 18 years+ - NCT05958706Recruiting
Testing how heart cells use fuel in heart failure
This study looks at how the heart uses energy fuel in people with heart failure, including those with type 2 diabetes. It may help researchers understand what’s going on inside the heart and how it could be treated in the future.
DüsseldorfAges 20–85 - NCT05977049Recruiting
Support program for adults with Takotsubo syndrome
This trial studies a psychosocial (emotional and coping) support approach for adults with Takotsubo syndrome. It may help patients deal with stress, anxiety, or adjustment related to the condition.
New York, New YorkAges 18 years+ - NCT06001073Recruiting
Heart and brain disease health prediction study
This study uses advanced health data to predict how heart and brain conditions may progress. It aims to help doctors provide better care for people with these diseases.
Xi'an, ShaanxiAges 3–80 - NCT06023186Recruiting
Effect of mavacamten on heart blood flow in HCM
This study tests whether the drug mavacamten (Camzyos) improves blood flow in the heart's small vessels for people with obstructive hypertrophic cardiomyopathy. You will take mavacamten as prescribed and have a PET/CT scan to measure your heart's blood flow reserve.
Charlottesville, VirginiaAges 18–85 - NCT06034405Recruiting
Checking spine tissue for heart amyloidosis signs
This trial is looking at leftover tissue from past spine surgeries to see if it contains signs of a heart condition called TTR amyloidosis. It may help find people who have this condition early.
Beverly Hills, CaliforniaAges 50 years+ - NCT06040242Recruiting
Exercise and heart rhythm study for ARVC patients
This study looks at how exercise affects heart rhythm in people with ARVC, a genetic heart condition. Participation involves supervised exercise sessions and heart monitoring to better understand safe activity levels.
Zurich, Canton of ZurichAges 14 years+ - NCT06052475Recruiting
Pacemaker upgrade study for heart failure
This trial is for people with a standard pacemaker that stimulates the right ventricle most of the time. It tests whether a newer type of pacemaker (CRT) can improve heart function and symptoms. If you have a weakened heart (LVEF between 35-50%) and your heart failure has gotten worse, this study may be a good fit.
CambridgeAges 18 years+ - NCT06143566RecruitingPhase 1/Phase 2
Polypill to prevent heart failure in diabetes and kidney disease
This trial tests a 'polypill' (a combination of several medicines in one pill) to prevent heart failure in people with type 2 diabetes and kidney disease. It may help reduce your risk of developing heart muscle problems.
Dallas, TexasAges 18–100 - NCT06145035RecruitingPhase 2
Stem cells from cord blood for heart failure
This trial tests whether stem cells from donated umbilical cord blood can improve heart function in people with heart failure caused by blocked arteries. You'll receive one or more infusions of these cells through a vein.
Miami, FloridaAges 21–85 - NCT06228924RecruitingPhase 1
Gene therapy for ARVC with PKP2 mutation
This trial tests a new gene therapy called TN-401 for people with ARVC caused by a specific PKP2 gene mutation. The goal is to see if the treatment is safe and can help reduce dangerous heart rhythms.
San Francisco, CaliforniaAges 18–65 - NCT06243653Recruiting
Heart microvessel function test for heart failure recovery
This trial looks at how tiny blood vessels in the heart affect improvement in heart pumping strength for people with heart failure. It tests whether a special procedure during heart catheterization can predict recovery.
SeoulAges 19 years+
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Common questions
- Are there clinical trials for cardiomyopathies?
- Yes. Clin2 currently lists 322 recruiting cardiomyopathies studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cardiomyopathies trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cardiomyopathies trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.