Clinical trials
Cardiovascular Disease Risk clinical trials
Below are recruiting cardiovascular disease risk clinical trials, each written for real people, not researchers. We’re tracking 366 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06533007Enrolling by invitation
How PDE3B affects metabolism in healthy adults
This study looks at how a protein called PDE3B affects your body's metabolism (how it uses energy). It may help researchers understand weight and insulin resistance better, which could lead to new treatments.
CambridgeAges 21–75 - NCT06397729Recruiting
Testing a new tool to support healthy habits in rural clinics
This study is testing a new way to help people improve their heart health by making healthy changes in their daily habits. It focuses on patients in rural primary care clinics who are at higher risk because of their weight.
St Louis, MissouriAges 18–64 - NCT06283758Recruiting
Ultrasound treatment for kidney fat to lower blood pressure
This trial tests a new ultrasound treatment that targets the fat pad around your kidney to lower blood pressure. It might be an option if your blood pressure is still high despite medication and you meet the size requirements for the fat pad.
Nanjing, JiangsuAges 18–65 - NCT06070194Recruiting
Heart health and eating patterns in short sleepers
This study tests whether changing the time window when you eat can improve heart health for people who naturally sleep 6.5 hours or less per night. You'll be asked to follow either a longer or shorter daily eating period while researchers measure blood pressure and other heart disease risk factors.
Baton Rouge, LouisianaAges 18–45 - NCT05782270RecruitingPhase 4
Blood thinner medicines after bypass surgery with artery unblocking
This trial studies which blood-thinning medicine combination is safest and most helpful after coronary bypass surgery combined with a procedure to unblock the artery (endarterectomy). It focuses on preventing dangerous blood clots while also avoiding excess bleeding.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06014515RecruitingEarly Phase 1
Single injection PET scan to study body metabolism
This study uses a single injection and a special type of PET scan to look at how your body's tissues use fuel (metabolism). It helps researchers learn more about normal and disease-related changes in the heart, liver, and other organs.
Sacramento, CaliforniaAges 18 years+ - NCT05921253RecruitingEarly Phase 1
Check a brain-heart device to reduce chemo heart risk
This early-phase study tests a “neuromodulation” device (stimulating nerves that may affect the heart and blood vessels) to help lower cardiovascular risks after certain cancer chemotherapy. It may be most relevant if you recently had an anthracycline-based treatment and also have other heart-risk factors.
Oklahoma City, OklahomaAges 18–99 - NCT05903950Recruiting
Air pollution study to help lower blood pressure
This trial tests whether an air-pollution–reduction approach in your home can help lower blood pressure. It focuses on adults with mildly high blood pressure and certain metabolic health markers.
DohaAges 18–60 - NCT05841784Recruiting
Mindfulness coaching for stress and mood after heart risk
This study tests a structured mindfulness program (MBCT-T) to help people who have elevated stress and/or mild anxiety or depression in the setting of heart disease or heart risk factors. It may help improve emotional well-being and stress levels while you live with these health concerns.
New York, New YorkAges 18 years+ - NCT05488431RecruitingPhase 2
Bempedoic acid to lower cholesterol and inflammation in HIV
This Phase 2 trial studies whether bempedoic acid can lower cholesterol and inflammation in people with HIV who are already on effective HIV medications. It may help reduce signs of artery inflammation that can contribute to heart and stroke risk.
Los Angeles, CaliforniaAges 40 years+ - NCT04444128Recruiting
Testing heart risk assessment using MRI T1 mapping
This study checks whether an MRI heart scan measure called “T1 mapping” can improve how doctors estimate heart disease risk in everyday people. You may join if you’re an adult and can have a contrast-enhanced heart MRI safely.
Frankfurt am Main, HesseAges 18 years+ - NCT04514445Recruiting
Study of genes in people with bicuspid aortic valve
This study looks for genetic (inherited) differences that may be linked to bicuspid aortic valve (BAV). It includes people with BAV and close family members to help understand why BAV happens and whether genes play a role.
KetteringAges 10–99 - NCT04101188Recruiting
Study how extra potassium affects blood vessels
This study looks at how eating more potassium may protect blood vessels in healthy people. You may be eligible if you have normal blood pressure and a normal heart rhythm test, and you do not have certain health conditions.
Newark, DelawareAges 18–45 - NCT03480633Recruiting
Heart failure precision medicine registry
This registry collects health and heart-related information to better understand heart failure (with preserved or reduced pumping strength) and guide more precise care. You may be asked to share tests and results, and help researchers learn which patterns match different types of heart failure.
Boston, MassachusettsAges 18 years+ - NCT03264352RecruitingPhase 4
Treatment for slightly high blood pressure in type 2 diabetes
This trial tests an intervention to help adults with type 2 diabetes who have “high-normal” blood pressure (not severely high). If you qualify, you may learn whether this approach improves blood pressure and related health outcomes over time.
Guangzhou, GuangdongAges 45–79 - NCT02669797Enrolling by invitation
Family-based program to help families eat dinner together
This study offers an intervention focused on family dinners to help children improve their eating habits. It targets children who eat family dinners rarely and have a higher weight range, to see if the program can help improve health over time.
Aurora, ColoradoAges 5–10 - NCT02016430Recruiting
Diet study to lower TMAO levels using gut microbes
This trial looks at whether a structured 12-week diet can lower a blood chemical called TMAO, which is linked to heart and kidney risk for some people. It may help you see if diet changes can shift gut microbes and reduce TMAO-related signals.
Cleveland, OhioAges 18 years+ - NCT07166822Recruiting
Can a mobile app help you stay active during pregnancy?
This study tests if using a mobile app can help pregnant women who are not very active to exercise more safely and improve their heart health. It's for women with low-risk pregnancies who want to use a simple smartphone tool.
Norfolk, VirginiaAges 18–45 - NCT07427589Recruiting
New Heart Tests in Sleep Apnea
This study looks at how sleep apnea affects your heart and blood vessels over time. It uses a sleep study and heart tests to see if certain measurements can predict heart health changes.
AntwerpAges 18 years+ - NCT07052799RecruitingPhase 3
Should you pause aspirin before a colonoscopy?
This trial compares stopping aspirin versus continuing it before a colonoscopy in people who take aspirin to prevent heart problems. The goal is to find out which approach is safer and works best.
Hong KongAges 18 years+ - NCT07608926Recruiting
Heart Health Management: Digital Tools vs. Traditional Care
This study compares a new way to manage heart disease risk factors using digital technology (like apps or remote monitoring) with the traditional doctor visit approach. It aims to see which method better helps people control high blood pressure, blood sugar, cholesterol, and weight over 2 years.
Cotignola, RavennaAges 40–75 - NCT07331103Recruiting
Can a special diet reduce inflammation for heart health?
This study tests whether a special diet can reduce inflammation and improve heart health in people over 55 who are at increased risk for heart disease but have not yet had a heart attack or stroke.
Cortona, ArezzoAges 55 years+ - NCT05708807Recruiting
Follow-up study of recovery after first-time stroke in Gothenburg
This study tracks how people recover after their first-ever stroke (either blocked artery stroke or bleeding in the brain). It may help doctors better understand recovery patterns and what support could work best over time.
GothenburgAges 18 years+ - NCT07247487Recruiting
Diet and Heart Health in Rosario
This study looks at how different diets (vegan, vegetarian, or omnivorous) affect heart health and metabolism in Rosario. It's a good fit if you're a generally healthy adult who has been following one of these diets for at least a year.
Rosario, Santa Fe ProvinceAges 18–65
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Common questions
- Are there clinical trials for cardiovascular disease risk?
- Yes. Clin2 currently lists 366 recruiting cardiovascular disease risk studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cardiovascular disease risk trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cardiovascular disease risk trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.