Clinical trials
Central Sleep Apnea clinical trials
Below are recruiting central sleep apnea clinical trials, each written for real people, not researchers. We’re tracking 99 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04007380Recruiting
Sleep problems after spinal cord injury study
This study looks at how sleep-disordered breathing (breathing problems during sleep) affects mood, thinking, and behavior after a spinal cord injury. It may help researchers understand the impact of these sleep breathing issues and guide better support for people after injury.
Toronto, OntarioAges 18 years+ - NCT06372847Recruiting
Sleep apnea nerve stimulation study
This trial tests a nerve-stimulation implant for sleep apnea when other treatments haven't worked. It may help if you have moderate to severe apnea, a BMI under 32, and have tried CPAP and a mouth device without success.
Edegem, AntwerpenAges 18 years+ - NCT06861686Recruiting
New classification for obstructive sleep apnea
This study is improving how doctors classify obstructive sleep apnea (a condition where your breathing stops and starts during sleep). It focuses on sleepiness and heart-related risks to help guide treatment. If you are 40 or older and have untreated OSA, you may be able to join.
Antwerp, AntwerpAges 40 years+ - NCT07113288Recruiting
Inspire implant for severe sleep apnea and higher weight
This study tests an implanted device (Inspire) that stimulates nerves to keep your airway open during sleep. It is for people with severe sleep apnea who cannot use or tolerate a CPAP machine, and who may have a higher body mass index.
Colorado Springs, ColoradoAges 18 years+ - NCT06477952RecruitingPhase 1/Phase 2
Dronabinol for sleep apnea
This study tests whether dronabinol, a cannabis-like medicine, can help people with moderate sleep apnea breathe better at night. It may be an option for those who haven't found other treatments helpful.
Chicago, IllinoisAges Up to 65 years - NCT05988385Recruiting
Treating sleep apnea to protect memory in older adults
This study tests whether treating sleep apnea can help protect memory and brain health in older adults. It involves using a CPAP machine or other treatments for sleep apnea and may include memory tests and brain scans over 2 years.
Tucson, ArizonaAges 55–85 - NCT06994650RecruitingPhase 3
Study of HRS9531 for sleep apnea and obesity
This trial tests an injection called HRS9531 to see if it helps people with obstructive sleep apnea (OSA) and obesity who already use a CPAP or similar breathing device. It may help by reducing weight and improving breathing during sleep.
Beijing, Beijing MunicipalityAges 18–75 - NCT03929549Recruiting
Testing a tool to predict jaw surgery failure for sleep apnea
This trial studies a way to predict which people with obstructive sleep apnea (OSA) may not do well after maxillomandibular advancement surgery (jaw advancement). It could help doctors choose the right treatment and avoid ineffective surgery.
Ann Arbor, MichiganAges 30–65 - NCT03948373Recruiting
Study of sleep apnea patients with normal blood pressure
This study is looking at a specific sleep-related condition (obstructive sleep apnea) in adults whose blood pressure is not high, and how their blood pressure rhythm changes over the day. If you have sleep apnea, participating could help researchers understand patterns that may affect long-term health.
LleidaAges 18–100 - NCT04130503Recruiting
Breathing device study after a recent ischemic stroke
This study looks at whether using a PAP breathing machine soon after an ischemic stroke helps sleep and recovery. It focuses on people who have moderate to severe obstructive sleep apnea diagnosed around the time of their stroke.
New Haven, ConnecticutAges 18 years+ - NCT04457154Recruiting
Registry for teens and young adults with OSA who can’t use CPAP
This study collects information in a registry to help doctors understand outcomes for young people with moderate-to-severe obstructive sleep apnea who cannot use CPAP and may use an implantable breathing stimulation device. You might qualify if you’ve tried and couldn’t tolerate CPAP and you’re able/willing to get and use the device and return for follow-ups and sleep tests.
Aurora, ColoradoAges 18–21 - NCT05156112Recruiting
PAP breathing treatment for veterans with PTSD and substance use
This trial studies whether using a PAP breathing device (a machine that helps keep airways open during sleep) can help veterans who have PTSD and a substance use disorder while they receive residential treatment. It’s specifically for people with obstructive sleep apnea and aims to see if this treatment is safe and helpful during recovery.
San Diego, CaliforniaAges 18 years+ - NCT05293600RecruitingPhase 1/Phase 2
Rescue medicine trial for sleep apnea after other treatments fail
This trial studies a “rescue” set of medicines for obstructive sleep apnea when two common treatments haven’t worked well enough. If you still have frequent breathing pauses during sleep, the study may test whether these medicines can reduce them and improve safety and symptoms.
Boston, MassachusettsAges 21–70 - NCT05917119Recruiting
Bright light therapy for obstructive sleep apnea symptoms
This study tests whether a “bright light” treatment can reduce daytime sleepiness in people with obstructive sleep apnea who are already using CPAP or BiPAP. It may help people feel more awake during the day without changing their sleep apnea device use.
Pittsburgh, PennsylvaniaAges 40–65 - NCT05958563Recruiting
CPAP may prevent COPD flare-ups in COPD-OSA overlap
This study tests whether using continuous positive airway pressure (CPAP) can reduce acute COPD flare-ups in people who also have sleep apnea. It may help by improving breathing during sleep and lowering the chance of worsening lung symptoms.
AngersAges 40 years+ - NCT06047353Recruiting
Helping people with sleep apnea try PAP therapy for the first time
This study tests whether health advocates can help people with moderate-to-severe sleep apnea start using a PAP machine. If you've never used a PAP or other sleep apnea treatment before, this trial may help you get support and guidance.
Miami, FloridaAges 18–100 - NCT06115018Recruiting
Oral device for sleep apnea after palate surgery
This study tests whether a special oral device (OPR) can help people with sleep apnea after they have had palate surgery. It looks at how well it works and if the benefits last over time.
TainanAges 18–100 - NCT06570616Recruiting
Reducing mask leaks during CPAP for sleep apnea
This study tests a method to help CPAP users with nasal masks who have high air leaks. It aims to find better ways to reduce unintentional leaking so treatment works more effectively.
São Paulo, BrazilAges 18 years+ - NCT06570629Recruiting
Fixing air leaks with nasal CPAP
This trial looks at ways to fix air leaks that happen when using a CPAP mask at night. It may help if you have sleep apnea and your CPAP is leaking a lot despite using a nasal mask.
São Paulo, BrazilAges 18 years+ - NCT06621511Recruiting
OurSleepKit: Helping couples stick with CPAP therapy
This study tests a program called OurSleepKit designed to help people with sleep apnea and their partners use CPAP therapy consistently. It may be a good fit if you and your partner live together and want to improve your sleep health together.
Boston, MassachusettsAges 18 years+ - NCT06851338Recruiting
Inspire therapy study for teens with Down syndrome and sleep apnea
This study tests a device called Inspire that stimulates the airway during sleep to treat obstructive sleep apnea in teenagers with Down syndrome who cannot use a CPAP machine or had a tonsillectomy that did not work well.
Phoenix, ArizonaAges 13–18 - NCT07254026Recruiting
Precision health and smart telerehabilitation for sleep apnea
This trial tests a smart home-based program using telerehabilitation to help people with obstructive sleep apnea. It aims to see if personalized health coaching and remote exercise can improve sleep and overall health.
TainanAges 20 years+ - NCT07331285Recruiting
Genio therapy study for moderate to severe sleep apnea
This trial studies a device called Genio that is implanted to help keep your airway open while you sleep. It is for people with moderate to severe sleep apnea who have not been helped by other treatments.
Miami, FloridaAges 22 years+ - NCT05501236Recruiting
Nerve stimulation for sleep apnea using neck nerve signals
This study tests a device that stimulates nerves in the neck to help keep your airway open during sleep for obstructive sleep apnea. If you fit the safety and sleep-study requirements, it may offer an alternative approach to improving breathing at night.
Nashville, TennesseeAges 18 years+
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Common questions
- Are there clinical trials for central sleep apnea?
- Yes. Clin2 currently lists 99 recruiting central sleep apnea studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a central sleep apnea trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a central sleep apnea trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.