Clinical trials
Central Sleep Apnea clinical trials
Below are recruiting central sleep apnea clinical trials, each written for real people, not researchers. We’re tracking 93 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04457154Recruiting
Registry for teens and young adults with OSA who can’t use CPAP
This study collects information in a registry to help doctors understand outcomes for young people with moderate-to-severe obstructive sleep apnea who cannot use CPAP and may use an implantable breathing stimulation device. You might qualify if you’ve tried and couldn’t tolerate CPAP and you’re able/willing to get and use the device and return for follow-ups and sleep tests.
Aurora, ColoradoAges 18–21 - NCT03948373Recruiting
Study of sleep apnea patients with normal blood pressure
This study is looking at a specific sleep-related condition (obstructive sleep apnea) in adults whose blood pressure is not high, and how their blood pressure rhythm changes over the day. If you have sleep apnea, participating could help researchers understand patterns that may affect long-term health.
LleidaAges 18–100 - NCT06851338Recruiting
Inspire therapy study for teens with Down syndrome and sleep apnea
This study tests a device called Inspire that stimulates the airway during sleep to treat obstructive sleep apnea in teenagers with Down syndrome who cannot use a CPAP machine or had a tonsillectomy that did not work well.
Phoenix, ArizonaAges 13–18 - NCT07331285Recruiting
Genio therapy study for moderate to severe sleep apnea
This trial studies a device called Genio that is implanted to help keep your airway open while you sleep. It is for people with moderate to severe sleep apnea who have not been helped by other treatments.
Miami, FloridaAges 22 years+ - NCT07254026Recruiting
Precision health and smart telerehabilitation for sleep apnea
This trial tests a smart home-based program using telerehabilitation to help people with obstructive sleep apnea. It aims to see if personalized health coaching and remote exercise can improve sleep and overall health.
TainanAges 20 years+ - NCT05958563Recruiting
CPAP may prevent COPD flare-ups in COPD-OSA overlap
This study tests whether using continuous positive airway pressure (CPAP) can reduce acute COPD flare-ups in people who also have sleep apnea. It may help by improving breathing during sleep and lowering the chance of worsening lung symptoms.
AngersAges 40 years+ - NCT06570629Recruiting
Fixing air leaks with nasal CPAP
This trial looks at ways to fix air leaks that happen when using a CPAP mask at night. It may help if you have sleep apnea and your CPAP is leaking a lot despite using a nasal mask.
São Paulo, BrazilAges 18 years+ - NCT06570616Recruiting
Reducing mask leaks during CPAP for sleep apnea
This study tests a method to help CPAP users with nasal masks who have high air leaks. It aims to find better ways to reduce unintentional leaking so treatment works more effectively.
São Paulo, BrazilAges 18 years+ - NCT06994650RecruitingPhase 3
Study of HRS9531 for sleep apnea and obesity
This trial tests an injection called HRS9531 to see if it helps people with obstructive sleep apnea (OSA) and obesity who already use a CPAP or similar breathing device. It may help by reducing weight and improving breathing during sleep.
Beijing, Beijing MunicipalityAges 18–75 - NCT06970171Enrolling by invitation
Willingness to use a sleep apnea mouthpiece
This trial tests how well people accept a mouthpiece (mandibular advancement device) to treat obstructive sleep apnea (a condition where your breathing stops and starts during sleep). If you have sleep apnea and can wear a device that moves your lower jaw forward while you sleep, you may be able to join.
Greifswald, Mecklenburg-VorpommernAges 18–75 - NCT06621511Recruiting
OurSleepKit: Helping couples stick with CPAP therapy
This study tests a program called OurSleepKit designed to help people with sleep apnea and their partners use CPAP therapy consistently. It may be a good fit if you and your partner live together and want to improve your sleep health together.
Boston, MassachusettsAges 18 years+ - NCT04130503Recruiting
Breathing device study after a recent ischemic stroke
This study looks at whether using a PAP breathing machine soon after an ischemic stroke helps sleep and recovery. It focuses on people who have moderate to severe obstructive sleep apnea diagnosed around the time of their stroke.
New Haven, ConnecticutAges 18 years+ - NCT06477952RecruitingPhase 1/Phase 2
Dronabinol for sleep apnea
This study tests whether dronabinol, a cannabis-like medicine, can help people with moderate sleep apnea breathe better at night. It may be an option for those who haven't found other treatments helpful.
Chicago, IllinoisAges Up to 65 years - NCT06047353Recruiting
Helping people with sleep apnea try PAP therapy for the first time
This study tests whether health advocates can help people with moderate-to-severe sleep apnea start using a PAP machine. If you've never used a PAP or other sleep apnea treatment before, this trial may help you get support and guidance.
Miami, FloridaAges 18–100 - NCT05988385Recruiting
Treating sleep apnea to protect memory in older adults
This study tests whether treating sleep apnea can help protect memory and brain health in older adults. It involves using a CPAP machine or other treatments for sleep apnea and may include memory tests and brain scans over 2 years.
Tucson, ArizonaAges 55–85 - NCT05917119Recruiting
Bright light therapy for obstructive sleep apnea symptoms
This study tests whether a “bright light” treatment can reduce daytime sleepiness in people with obstructive sleep apnea who are already using CPAP or BiPAP. It may help people feel more awake during the day without changing their sleep apnea device use.
Pittsburgh, PennsylvaniaAges 40–65 - NCT05501236Recruiting
Nerve stimulation for sleep apnea using neck nerve signals
This study tests a device that stimulates nerves in the neck to help keep your airway open during sleep for obstructive sleep apnea. If you fit the safety and sleep-study requirements, it may offer an alternative approach to improving breathing at night.
Nashville, TennesseeAges 18 years+ - NCT05293600RecruitingPhase 1/Phase 2
Rescue medicine trial for sleep apnea after other treatments fail
This trial studies a “rescue” set of medicines for obstructive sleep apnea when two common treatments haven’t worked well enough. If you still have frequent breathing pauses during sleep, the study may test whether these medicines can reduce them and improve safety and symptoms.
Boston, MassachusettsAges 21–70 - NCT05156112Recruiting
Sleep apnea treatment for veterans with PTSD and substance use
This study tests whether treating sleep apnea with a breathing device during a residential program helps veterans with post-traumatic stress disorder (PTSD) and substance use problems. It aims to improve their recovery and quality of life.
San Diego, CaliforniaAges 18 years+ - NCT04129229Enrolling by invitation
Tongue device study for moderate-to-severe sleep apnea and snoring
This trial tests a tongue retractor device to help treat obstructive sleep apnea and reduce snoring in adults. You may be eligible if you have moderate-to-severe sleep apnea and can avoid other common treatments during the study.
Brighton, MassachusettsAges 18 years+ - NCT07329283Recruiting
Nighttime nutrition and sleep health study
This study looks at how eating at night affects your sleep and body clock. You will spend two nights in a sleep lab to test the effects of a small meal before bed.
Salt Lake City, UtahAges 18–35
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Common questions
- Are there clinical trials for central sleep apnea?
- Yes. Clin2 currently lists 93 recruiting central sleep apnea studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a central sleep apnea trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a central sleep apnea trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.