Clinical trials
Central Sleep Apnea clinical trials
Below are recruiting central sleep apnea clinical trials, each written for real people, not researchers. We’re tracking 99 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06834724Recruiting
CPAP for sleep apnea and chronic pain
This study looks at whether CPAP treatment improves pain and daily life in people who have both sleep apnea and chronic pain. It tests if starting CPAP for the first time can help these symptoms.
BrusselsAges 18 years+ - NCT02431507Recruiting
First test of an implant device to prevent sleep apnea pauses
This trial is testing whether a new implanted device is safe and feasible for people with moderate to severe obstructive sleep apnea. It may help if you cannot tolerate CPAP (a common breathing device) and your apnea is caused by airflow blockage at the back of the tongue area.
San Francisco, CaliforniaAges 21–70 - NCT06789770Recruiting
Nasal vs mouth breathing during drug-induced sleep
This study compares how breathing through the nose versus mouth affects sleep, using both natural and medication-induced sleep. It may help people with sleep apnea understand their breathing patterns better.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07225686RecruitingPhase 3
Maridebart Cafraglutide for sleep apnea in adults on CPAP
This study is testing whether a new medicine, called Maridebart Cafraglutide, can help people with obstructive sleep apnea who are already using a CPAP machine. The medicine may help with weight loss and potentially improve sleep apnea. Participants will either receive the medicine or a placebo (an inactive substance), and the study lasts for several months.
Northridge, CaliforniaAges 18–99 - NCT04814420Recruiting
Study heart scarring in sleep apnea, with or without atrial fibrillation
This pilot study looks at whether obstructive sleep apnea leads to heart scarring (called atrial fibrosis), especially in people with and without an irregular heart rhythm (atrial fibrillation). It may help researchers understand who is at higher risk and why, using sleep testing and heart imaging.
New Orleans, LouisianaAges 18–75 - NCT06994247Recruiting
Boosting CPAP use in severe sleep apnea
This study tests whether motivation and psychological support can help people with severe sleep apnea use their CPAP machine more consistently over three months.
Split, DalmatiaAges 18 years+ - NCT02703207Recruiting
Sleep apnea and COPD effects in older veterans
This study looks at how sleep apnea affects thinking skills and overall health in older veterans who also have COPD. It may help researchers understand what changes to target to improve daytime functioning and wellbeing.
Detroit, MichiganAges 60–89 - NCT07434050RecruitingPhase 3
Study of XW003 for obesity with sleep apnea on CPAP therapy
This trial tests an investigational drug called XW003 to see if it helps people with obesity and obstructive sleep apnea who are already using a positive airway pressure (PAP) machine, like CPAP. It aims to improve weight loss and sleep apnea symptoms.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07226765RecruitingPhase 3
Study of an injectable medicine for sleep apnea in people not using breathing devices
This trial tests an injectable medicine (maridebart cafraglutide) versus a placebo to see if it helps reduce sleep apnea episodes in people who do not use or cannot use a CPAP or similar breathing machine. It may be an option if you have moderate to severe sleep apnea and are looking for a non-device treatment.
Northridge, CaliforniaAges 18–99 - NCT07090395Recruiting
Expanding use of EVO oral appliance for severe sleep apnea
This trial tests whether an EVO oral appliance can treat severe obstructive sleep apnea in people who haven't used other treatments recently. It aims to see if the device works for a wider group of patients.
New York, New YorkAges 18–80 - NCT07345312Recruiting
Testing BodySleep algorithm for child sleep apnea diagnosis
This study tests a new computer algorithm (called BodySleep) that analyzes sleep data to help diagnose obstructive sleep apnea in children. It aims to make diagnosis faster and easier for kids who are already scheduled for a sleep study.
Nancy, Grand EstAges 2–18 - NCT06944782Recruiting
Can mouth muscle tests help diagnose sleep apnea?
This study tests a new device that measures muscle activity in your mouth to diagnose sleep apnea—without needing to spend the night in a lab. If you've already had a sleep test showing either no sleep apnea or moderate to severe sleep apnea, and you're not using CPAP daily, you may be able to help.
San Diego, CaliforniaAges 18–80 - NCT07387094RecruitingPhase 3
A study of XW003 for obesity with sleep apnea (no CPAP)
This trial tests an investigational weekly injection called XW003 for weight loss in people who have obesity and moderate-to-severe sleep apnea but do not use a CPAP machine. It aims to see if the drug can help with weight loss and improve sleep apnea without the need for a breathing machine.
Beijing, Beijing MunicipalityAges 18–75 - NCT07601724Recruiting
How fluid buildup affects sleep apnea in heart failure
This study looks at how excess fluid in the body affects sleep apnea (pauses in breathing during sleep) in people hospitalized with heart failure. Researchers will measure sleep apnea before and after treatment to reduce the fluid, which may help doctors better manage both conditions together.
JerusalemAges 18 years+ - NCT07087587Recruiting
Sleep apnea treatment for AFib: a personalized trial
This study tests whether treating sleep apnea with a CPAP machine can reduce the number of AFib episodes you have. It's a personalized 'N-of-1' trial, meaning you'll try both CPAP and no CPAP at different times to see what works best for you.
Cleveland, OhioAges 18–85 - NCT07492420Recruiting
Sleep position therapy for mild sleep apnea
This study tests if a special sleep system that keeps you on your side can improve mild obstructive sleep apnea. You may qualify if you have mild sleep apnea and are looking for a non-surgical treatment option.
St Louis, MissouriAges 18 years+ - NCT06755840Recruiting
Sleep breathing problems and multiple health conditions study
This study is for people who may have sleep-related breathing problems (like sleep apnea). It looks at how these issues connect with other health conditions. Participants will do a one-night sleep test and some simple health checks at Xiangya Hospital.
ChangshaAges Any age - NCT06762873RecruitingEarly Phase 1
Testing a nerve therapy for Latin Americans with sleep apnea
This trial tests a new nerve-stimulation therapy called Neuromod to treat moderate-to-severe sleep apnea in people who do not have access to other treatments. If you qualify, you would be part of a study to see if this implant helps improve your breathing during sleep.
AsunciónAges 18 years+ - NCT05267808Recruiting
Using sleep study patterns to guide future OSA treatment
This study looks at results from a sleep test to better understand the different types (“endotypes”) of obstructive sleep apnea. Your information may help doctors choose the next best step—often a procedure called drug-induced sleep endoscopy (DISE)—to guide treatment.
EdegemAges 18 years+ - NCT06314477Recruiting
CPAP treatment for severe uncontrolled asthma with sleep apnea
This trial tests if CPAP (a mask that helps you breathe at night) can improve asthma control in people who have both severe uncontrolled asthma and sleep apnea (a condition where breathing stops and starts during sleep). You should not have been hospitalized for asthma in the last month.
Barcelona, SpainAges 18 years+ - NCT07446634Recruiting
Jaw advancement surgery for sleep apnea
This study tests jaw advancement surgery for people with obstructive sleep apnea who haven't been helped by CPAP or mouthpieces. It looks at whether moving the jaw forward can improve breathing during sleep.
Falun, Dalarna CountyAges 18–70 - NCT06566482RecruitingPhase 4
Medicine for pain after surgery in sleep apnea patients
This trial tests a combination of two medicines (dexmedetomidine and esketamine) given in small doses to help with pain after surgery. It is for people who have sleep apnea or are at risk for it, and who are having chest or belly surgery with a scope.
Beijing, Beijing MunicipalityAges 18–80 - NCT06059352Recruiting
Sleep and hearing in autism spectrum disorder study
This study looks at how sleep problems might affect the way people with autism process sounds. It aims to find better ways to help with listening difficulties.
Loma Linda, CaliforniaAges 6–17 - NCT06564896Recruiting
Comparing sleep apnea treatments (CPAP vs alternatives)
This trial compares different positive airway pressure (PAP) machines to see which works best for people with moderate to severe sleep apnea. If you have been diagnosed but haven't used a CPAP yet, this study may help find the best option for you.
Cheras, Kuala LumpurAges 18 years+
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Common questions
- Are there clinical trials for central sleep apnea?
- Yes. Clin2 currently lists 99 recruiting central sleep apnea studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a central sleep apnea trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a central sleep apnea trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.