Clinical trials
Cerebrospinal Fluid clinical trials
Below are recruiting cerebrospinal fluid clinical trials, each written for real people, not researchers. We’re tracking 51 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07831044Recruiting
Study of spinal fluid dynamics in normal pressure hydrocephalus
This study looks at how spinal fluid moves and flows in people with normal pressure hydrocephalus (NPH), a condition where extra fluid builds up in the brain and can cause problems with walking, thinking, or bladder control. Researchers hope to learn more about the condition, which could help improve diagnosis and treatment.
Daejeon, Jung-guAges 55–80 - NCT07541612Recruiting
Monitoring Spinal Cord Blood Flow During Aortic Surgery
This study tests a non-invasive monitoring device (NIRS) that tracks blood flow to the spinal cord during planned aortic surgery. The goal is to better understand and prevent spinal cord damage that can cause paralysis after major aortic procedures.
Naples, ItalyAges 18 years+ - NCT07411690Recruiting
Spinal fluid leak after brain tumor surgery
This trial checks for spinal fluid leaks after surgery to remove brain tumors. If you are having a planned first-time surgery for a tumor in the upper part of the brain, you may be eligible.
WarsawAges 18 years+ - NCT04421846Recruiting
Studying the causes of severe seizures and immune brain swelling
This study looks at what causes severe seizure episodes (“status epilepticus”) and a related immune condition that affects the brain (“dysimmune encephalitis”). The goal is to better understand the disease process, which may guide future care.
ParisAges 2 years+ - NCT07368348Recruiting
Nasal splint vs. flap for CSF leak repair
This trial compares two surgical techniques to repair a cerebrospinal fluid leak (a leak of the fluid around your brain) through the nose. It is for people who have leaks on both sides and have specific conditions in their nasal passage that might make the repair more complex.
Kafr Elsheikh, KafrelsheikhAges 18–70 - NCT06131801Recruiting
Crushed venetoclax tablet solution study for blood cancers
This study checks how the body handles venetoclax when it's given as a liquid made from crushed tablets. It's for children and young adults with blood cancers who already take venetoclax crushed or through a feeding tube.
Aurora, ColoradoAges birth–38 years - NCT04523909Recruiting
Testing spinal fluid inflammation changes after aortic surgery
This study tracks inflammation-related lab markers in spinal fluid taken through a temporary drain during and after thoracic aortic surgery. It may help doctors understand what inflammatory changes happen around surgery and how they relate to recovery.
NijmegenAges 18 years+ - NCT07865182Recruiting
Metabolites study in spontaneous brain bleeding
This study looks at chemical byproducts in the body of people with a type of brain bleed called subarachnoid hemorrhage (SAH), which is a bleed in the space around the brain. The goal is to find patterns that might help doctors understand the condition better and improve future care.
Lisbon, Lisbon DistrictAges 18 years+ - NCT07651826Recruiting
Study of Immiseal Dural Sealant in Brain and Spine Surgery
This study tracks how well Immiseal, a special sealing material, works when applied during brain or spine surgery to prevent fluid leaks from the protective membrane around the brain and spinal cord. You'll be followed after surgery to see how well the sealant performs and if you have any side effects.
RigaAges 18–75 - NCT07653893Recruiting
T-DXd for breast cancer that has spread to the brain
This study is looking at how well the drug trastuzumab deruxtecan (Enhertu) works for women and men with HER2-positive breast cancer that has spread to the brain. Researchers want to see how much of the drug gets into the spinal fluid and if it helps shrink brain tumors.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06711731Recruiting
Registry for spinal CSF leak and post-dural headache
This registry collects information from people with suspected spinal CSF leak (a condition where fluid leaks from around your spine) or headaches after a spinal procedure. By joining, you help researchers learn more about these conditions and improve future care.
Freiburg im BreisgauAges Any age - NCT07560865RecruitingPhase 1
New Cell Therapy for Recurring Brain Cancer
This study tests FT536, a new cell-based treatment, for people with a specific type of brain cancer (WHO Grade 4 astrocytoma) that has come back after standard treatment. The trial combines the new therapy with surgery to see if it can help stop the cancer from growing further.
Minneapolis, MinnesotaAges 18–75 - NCT07567664Enrolling by invitation
Brain Changes in Neurodegenerative Diseases: A Tracking Study
This research study tracks how brain damage progresses in rare neurodegenerative diseases like frontotemporal dementia, primary progressive aphasia, PSP, CBS, and ALS. Researchers use brain imaging and tests to understand how these diseases spread in the brain, which could help develop better treatments.
Milan, LombardyAges 20–85 - NCT07517913Recruiting
Testing how urolithin A enters the spinal fluid
This study checks how a natural compound called urolithin A moves into the fluid around the brain and spine after you take it. It may help researchers understand if it can be used for brain health.
PuneAges 18–45 - NCT07503704Recruiting
Studying breast cancer that spread to the brain
This study looks at genetic material from spinal fluid to better understand breast cancer that has spread to the brain or its lining. It may help doctors find new ways to treat this type of cancer.
DublinAges 18–99 - NCT07481396Recruiting
Studying brain injury after cardiac arrest through spinal fluid
This trial is looking at the spinal fluid of people who survived a cardiac arrest outside the hospital and are being treated for brain injury. The goal is to learn more about brain damage and find new ways to help patients recover.
Daejeon, Jung-guAges 18 years+ - NCT07476781Recruiting
Liquid biopsy study for solid tumours and brain tumours
This study collects samples of spinal fluid and blood from people with solid tumours that have spread to the brain or spine, or who have primary brain tumours. The goal is see if these samples can help doctors detect and monitor these cancers more easily.
Toronto, OntarioAges 18 years+ - NCT07435649Recruiting
New test for finding germs in spinal fluid during brain infections
This study tests a new type of test called Delve Detect that looks for germs in spinal fluid from people suspected of having a brain or spinal cord infection. It helps doctors find the cause faster and more accurately.
San Francisco, CaliforniaAges Any age - NCT07432113Recruiting
Predicting meningitis and encephalitis causes from spinal fluid
This trial tests a method to quickly identify the cause of meningitis or encephalitis by looking at your symptoms and spinal fluid results. It may help doctors choose the right treatment faster.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT07398170Recruiting
Searching for tumor cells in fluid for recurrent meningioma
This study looks for tumor cells in your blood or spinal fluid to see if they can help track aggressive meningiomas that have come back. It may help doctors understand your cancer better and guide future treatments.
Montpellier, FranceAges 18 years+ - NCT07380477Recruiting
Infection risk study for external ventricular drains
This trial looks at whether the fluid from your brain drain (called CSF) can help predict infections. It compares samples taken from different spots on the drain to find better ways to catch infections early.
CopenhagenAges 18 years+ - NCT06624488Recruiting
Brain injury markers after cardiac arrest and outlook
This study looks at certain proteins in the fluid around the brain and in the blood after a cardiac arrest. These proteins may help doctors predict how the patient will recover, which could guide their care.
BeijingAges 18–80 - NCT07353502Recruiting
Early Alzheimer's brain connection study
This study looks at a specific brain pathway that may be linked to early memory loss in Alzheimer's disease. It compares people with early Alzheimer's to healthy older adults to understand how connections between brain cells start to break down.
Yiwu, ZhejiangAges 50 years+ - NCT07312240Recruiting
Biomarkers in ALS: A long-term study
This study is looking for people with ALS to help doctors understand how certain biological markers (biomarkers) change over time. It involves a lumbar puncture (spinal tap) to collect fluid from your spine and regular check-ups.
Milan, LombardyAges 18 years+
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Common questions
- Are there clinical trials for cerebrospinal fluid?
- Yes. Clin2 currently lists 51 recruiting cerebrospinal fluid studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cerebrospinal fluid trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cerebrospinal fluid trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.