Clinical trials
Cerebrospinal Fluid clinical trials
Below are recruiting cerebrospinal fluid clinical trials, each written for real people, not researchers. We’re tracking 51 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05898074Recruiting
Testing a new gel during endoscopic skull base surgery
This trial looks at a new RADA16 hydrogel to see if it can help during an endoscopic surgery through the nose for a skull base tumor or a cerebrospinal fluid (CSF) leak. You might be a candidate if you are already planned for this specific type of nasal surgery and meet key safety requirements.
Indianapolis, IndianaAges 18 years+ - NCT06075693Recruiting
Spinal fluid markers for myotonic dystrophy
This study looks for markers in spinal fluid that could help doctors better understand myotonic dystrophy type 1 (DM1). It involves a spinal tap and MRI scan. It may help people with DM1 and healthy volunteers learn more about the condition.
Boston, MassachusettsAges 18 years+ - NCT06086561Recruiting
Testing a wireless device to monitor CSF shunt flow
This study tests a new wireless device that measures fluid flow in a CSF shunt (a tube that drains fluid from the brain). You may join if you have a shunt under your skin across your collarbone and can use or be nearby the device for a month.
Tampa, FloridaAges 5–80 - NCT06119061RecruitingPhase 4
Telavancin levels in patients with external ventricular drain
This study measures how much of the antibiotic telavancin reaches the fluid around your brain and spine when you have a drain in place. It will help doctors understand if this drug is effective for treating brain infections.
Lexington, KentuckyAges 18–85 - NCT06370845RecruitingEarly Phase 1
Smell test to find natural odor in spinal fluid
This study investigates whether a natural smell can be detected in the fluid around your brain and spine (cerebrospinal fluid) after you sniff it. It aims to understand how smells enter the brain in people with different body weights who are already scheduled for a routine spinal tap.
BaselAges 18–60 - NCT06406790RecruitingPhase 4
Studying a new sealant for brain surgery
This trial tests a product called CraniSeal, which is used to help seal the covering of the brain (the dura) after surgery. It may lower the risk of fluid leaks after certain types of planned brain surgeries.
Los Angeles, CaliforniaAges 18 years+ - NCT06482463Recruiting
D-lactate test for meningitis in patients with a brain drain
This study checks if a substance called D-lactate in the fluid around your brain can help diagnose meningitis that develops in the hospital after a brain drain (ventriculostomy). It aims to improve diagnosis.
ToulouseAges 18 years+ - NCT06486909Recruiting
Shunt need after brain aneurysm bleed: role of early high blood sugar
This study looks at whether high blood sugar levels early after a brain aneurysm bleed affect the need for a shunt (a tube to drain fluid from the brain). It aims to help doctors understand who might need this treatment.
AarauAges 18 years+ - NCT06624488Recruiting
Brain injury markers after cardiac arrest and outlook
This study looks at certain proteins in the fluid around the brain and in the blood after a cardiac arrest. These proteins may help doctors predict how the patient will recover, which could guide their care.
BeijingAges 18–80 - NCT06636201Recruiting
Cerebrospinal fluid study for surgery patients
This study collects and analyzes spinal fluid from patients having surgery with spinal anesthesia. It aims to learn more about the fluid's composition to help understand neurological conditions.
Hangzhou, ZhejiangAges birth–90 years - NCT06711731Recruiting
Registry for spinal CSF leak and post-dural headache
This registry collects information from people with suspected spinal CSF leak (a condition where fluid leaks from around your spine) or headaches after a spinal procedure. By joining, you help researchers learn more about these conditions and improve future care.
Freiburg im BreisgauAges Any age - NCT07153211Recruiting
Chemicals in spinal fluid and blood during spinal cord stimulation for nerve pain
This study is testing a spinal cord stimulation treatment for long-term nerve pain. It will look at certain chemicals in your spinal fluid and blood to understand how the treatment works.
BydgoszczAges 18–80 - NCT07216157Recruiting
Sealant vs no sealant for skull base surgery
This trial tests whether using a sealant after skull base surgery helps prevent spinal fluid leaks. It compares patients who get a sealant with those who don't.
WarsawAges 18 years+ - NCT07312240Recruiting
Biomarkers in ALS: A long-term study
This study is looking for people with ALS to help doctors understand how certain biological markers (biomarkers) change over time. It involves a lumbar puncture (spinal tap) to collect fluid from your spine and regular check-ups.
Milan, LombardyAges 18 years+ - NCT07353502Recruiting
Early Alzheimer's brain connection study
This study looks at a specific brain pathway that may be linked to early memory loss in Alzheimer's disease. It compares people with early Alzheimer's to healthy older adults to understand how connections between brain cells start to break down.
Yiwu, ZhejiangAges 50 years+ - NCT07380477Recruiting
Infection risk study for external ventricular drains
This trial looks at whether the fluid from your brain drain (called CSF) can help predict infections. It compares samples taken from different spots on the drain to find better ways to catch infections early.
CopenhagenAges 18 years+ - NCT02855476Recruiting
Collecting spinal fluid samples to help Huntington’s research
This study gathers small samples of spinal fluid from people affected by Huntington’s disease. Researchers use these samples to better understand the disease and support future treatments. If you join, you’ll need to follow their sample and visit schedule.
Englewood, ColoradoAges 11–75 - NCT02890641Recruiting
Study of brain signals and genes in hard-to-treat epilepsy
This study looks at genetic factors and brain electrical activity in children whose seizures are difficult to control with standard medicines. It also involves exams like MRI and possibly procedures under anesthesia, to better understand seizure causes and help future care.
ParisAges 3 months–25 years - NCT07442929Recruiting
Crystal formation study in spinal fluid
This trial looks at how certain substances form crystals in the fluid around the brain and spine. It may help researchers understand conditions like normal pressure hydrocephalus.
Innsbruck, TyrolAges 18 years+ - NCT07481396Recruiting
Studying brain injury after cardiac arrest through spinal fluid
This trial is looking at the spinal fluid of people who survived a cardiac arrest outside the hospital and are being treated for brain injury. The goal is to learn more about brain damage and find new ways to help patients recover.
Daejeon, Jung-guAges 18 years+ - NCT06861244RecruitingPhase 2
ETMR brain tumor trial for children
This trial is for children with a rare brain tumor (ETMR) who have not had radiation. Depending on how much tumor is left after surgery and if it has spread, the study compares giving radiation early versus high-dose chemotherapy.
Birmingham, AlabamaAges Any age - NCT07503704Recruiting
Studying breast cancer that spread to the brain
This study looks at genetic material from spinal fluid to better understand breast cancer that has spread to the brain or its lining. It may help doctors find new ways to treat this type of cancer.
DublinAges 18–99 - NCT07560865RecruitingPhase 1
New Cell Therapy for Recurring Brain Cancer
This study tests FT536, a new cell-based treatment, for people with a specific type of brain cancer (WHO Grade 4 astrocytoma) that has come back after standard treatment. The trial combines the new therapy with surgery to see if it can help stop the cancer from growing further.
Minneapolis, MinnesotaAges 18–75 - NCT07651826Recruiting
Study of Immiseal Dural Sealant in Brain and Spine Surgery
This study tracks how well Immiseal, a special sealing material, works when applied during brain or spine surgery to prevent fluid leaks from the protective membrane around the brain and spinal cord. You'll be followed after surgery to see how well the sealant performs and if you have any side effects.
RigaAges 18–75
Hear when a new Cerebrospinal Fluid trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for cerebrospinal fluid?
- Yes. Clin2 currently lists 51 recruiting cerebrospinal fluid studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cerebrospinal fluid trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cerebrospinal fluid trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.