Clinical trials
Cerebrospinal Fluid clinical trials
Below are recruiting cerebrospinal fluid clinical trials, each written for real people, not researchers. We’re tracking 51 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07216157Recruiting
Sealant vs no sealant for skull base surgery
This trial tests whether using a sealant after skull base surgery helps prevent spinal fluid leaks. It compares patients who get a sealant with those who don't.
WarsawAges 18 years+ - NCT07153211Recruiting
Chemicals in spinal fluid and blood during spinal cord stimulation for nerve pain
This study is testing a spinal cord stimulation treatment for long-term nerve pain. It will look at certain chemicals in your spinal fluid and blood to understand how the treatment works.
BydgoszczAges 18–80 - NCT07129603Recruiting
Detecting Brain Complications After a Non-Traumatic Bleed
This study looks for clues in your blood or spinal fluid that might predict brain spasms, delayed damage, or infections after a brain bleed. If you already need a drain to remove fluid, you could be a candidate.
DebrecenAges 18 years+ - NCT06086561Recruiting
Testing a wireless device to monitor CSF shunt flow
This study tests a new wireless device that measures fluid flow in a CSF shunt (a tube that drains fluid from the brain). You may join if you have a shunt under your skin across your collarbone and can use or be nearby the device for a month.
Tampa, FloridaAges 5–80 - NCT07067736Recruiting
Cefazolin Dose Before Shunt Surgery: Checking Brain Fluid Levels
This study measures how well the antibiotic cefazolin reaches the fluid around your brain and spine when given right before shunt surgery. It may help doctors choose the best dose to prevent infections.
StrasbourgAges 18 years+ - NCT06861244RecruitingPhase 2
ETMR brain tumor trial for children
This trial is for children with a rare brain tumor (ETMR) who have not had radiation. Depending on how much tumor is left after surgery and if it has spread, the study compares giving radiation early versus high-dose chemotherapy.
Birmingham, AlabamaAges Any age - NCT06502431Recruiting
MRI study of fluid flow in Chiari malformation type I
This study uses MRI to look at how fluid moves around the brain in people with Chiari malformation type I, a condition where brain tissue extends into the spinal canal. It aims to improve understanding of the condition and may help with future treatment decisions.
Amiens, PicardieAges 18–50 - NCT06486909Recruiting
Shunt need after brain aneurysm bleed: role of early high blood sugar
This study looks at whether high blood sugar levels early after a brain aneurysm bleed affect the need for a shunt (a tube to drain fluid from the brain). It aims to help doctors understand who might need this treatment.
AarauAges 18 years+ - NCT06482463Recruiting
D-lactate test for meningitis in patients with a brain drain
This study checks if a substance called D-lactate in the fluid around your brain can help diagnose meningitis that develops in the hospital after a brain drain (ventriculostomy). It aims to improve diagnosis.
ToulouseAges 18 years+ - NCT06406790RecruitingPhase 4
Studying a new sealant for brain surgery
This trial tests a product called CraniSeal, which is used to help seal the covering of the brain (the dura) after surgery. It may lower the risk of fluid leaks after certain types of planned brain surgeries.
Los Angeles, CaliforniaAges 18 years+ - NCT06370845RecruitingEarly Phase 1
Smell test to find natural odor in spinal fluid
This study investigates whether a natural smell can be detected in the fluid around your brain and spine (cerebrospinal fluid) after you sniff it. It aims to understand how smells enter the brain in people with different body weights who are already scheduled for a routine spinal tap.
BaselAges 18–60 - NCT05072691Recruiting
Tests spinal fluid proteins to predict multiple sclerosis outlook
This study checks specific proteins in spinal fluid to see whether they can predict how multiple sclerosis (or related symptoms like optic neuritis) may go over time. It may help doctors better estimate prognosis using results from tests you may already be having.
BrusselsAges 18 years+ - NCT06119061RecruitingPhase 4
Telavancin levels in patients with external ventricular drain
This study measures how much of the antibiotic telavancin reaches the fluid around your brain and spine when you have a drain in place. It will help doctors understand if this drug is effective for treating brain infections.
Lexington, KentuckyAges 18–85 - NCT06075693Recruiting
Spinal fluid markers for myotonic dystrophy
This study looks for markers in spinal fluid that could help doctors better understand myotonic dystrophy type 1 (DM1). It involves a spinal tap and MRI scan. It may help people with DM1 and healthy volunteers learn more about the condition.
Boston, MassachusettsAges 18 years+ - NCT05890781Recruiting
Study pediatric cancer using lab-made immune organoids
This trial uses special lab models (“immune organoids”) to study certain cancers in children and young people. It may help researchers learn what those cancers do and improve future treatment ideas.
VillejuifAges Up to 25 years - NCT05898074Recruiting
Testing a new gel during endoscopic skull base surgery
This trial looks at a new RADA16 hydrogel to see if it can help during an endoscopic surgery through the nose for a skull base tumor or a cerebrospinal fluid (CSF) leak. You might be a candidate if you are already planned for this specific type of nasal surgery and meet key safety requirements.
Indianapolis, IndianaAges 18 years+ - NCT05419076RecruitingPhase 2
SRS radiation for small cell lung cancer with brain spread
This Phase 2 trial tests a type of focused radiation (stereotactic radiosurgery, or SRS) for people with small cell lung cancer that has spread to the brain. It looks at whether this approach can treat brain metastases when the cancer has limited to a certain number of spots.
Basking Ridge, New JerseyAges 18 years+ - NCT05212272Recruiting
MRI plus cognitive testing during glioma chemoradiation
This study uses MRI scans and related brain/cognitive testing while you receive standard chemotherapy and radiation for a high-grade brain tumor. It aims to see how MRI measures and brain testing may relate to your treatment response or brain function.
Winston-Salem, North CarolinaAges 18 years+ - NCT05050864Recruiting
Stent versus brain-surgery options for idiopathic pressure
This study compares two treatment approaches for idiopathic intracranial hypertension (high pressure in the brain) that has not improved with usual medical treatment. It may help doctors learn which option works better and is safer for people with specific scan and eye findings.
Paris, ParisAges 18 years+ - NCT04099823Recruiting
MRI study of spinal fluid flow in memory or balance problems
This study uses MRI to look at how spinal fluid moves inside and around the brain. It aims to better understand conditions that can affect thinking, memory, balance, and coordination—such as normal pressure hydrocephalus—or compare with healthy people.
Rochester, MinnesotaAges 18 years+ - NCT04692324Recruiting
Test spinal fluid tests to help identify brain tumor types
This study looks at spinal fluid (cerebrospinal fluid, or CSF) to find markers that may signal a brain or spinal tumor or related abnormal growth. If you have a suspected tumor near the CSF spaces, these results may help doctors better classify what’s going on.
Rochester, MinnesotaAges Any age - NCT04471740Recruiting
Study of hydrocephalus and sleep apnea
This study looks at people who may have normal-pressure hydrocephalus (fluid-related swelling in the brain) and also focuses on sleep apnea. It may help researchers understand whether treating or studying sleep issues could improve symptoms related to this condition.
Valencia, ValenciaAges 18 years+ - NCT04012411Recruiting
Testing brain fluid biomarkers in Huntington’s disease
This study looks at specific “biomarkers” (measurable signs) found in cerebrospinal fluid, to better understand Huntington’s disease. The results may help researchers track the disease and improve future tests or treatments.
MontpellierAges 18 years+ - NCT02890641Recruiting
Study of brain signals and genes in hard-to-treat epilepsy
This study looks at genetic factors and brain electrical activity in children whose seizures are difficult to control with standard medicines. It also involves exams like MRI and possibly procedures under anesthesia, to better understand seizure causes and help future care.
ParisAges 3 months–25 years
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Common questions
- Are there clinical trials for cerebrospinal fluid?
- Yes. Clin2 currently lists 51 recruiting cerebrospinal fluid studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cerebrospinal fluid trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cerebrospinal fluid trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.