Clinical trials
Fluid Responsiveness clinical trials
Below are recruiting fluid responsiveness clinical trials, each written for real people, not researchers. We’re tracking 26 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06390423Recruiting
Leg raise and fluid test for heart response in shock
This trial tests a simple bedside test (raising your legs and giving a small amount of fluid) to see how well your heart responds. It is for patients in the ICU with vasodilatory shock and severe lung injury who are on a ventilator.
Saint Cloud, MinnesotaAges 30–90 - NCT07653568Recruiting
Comparing two ultrasound methods to guide fluid therapy in septic patients on ventilators
This study tests whether a neck ultrasound (carotid Doppler) or a heart ultrasound (echocardiography) is better at determining how much fluid a septic patient on a ventilator needs. If you or your loved one is in the ICU with sepsis on a breathing machine, this trial helps doctors choose the best way to give fluids that can improve blood pressure and organ function.
Islamabad, Federal AreaAges 12 years+ - NCT06772038Recruiting
Fluid response and vein health during fluid bolus in ICU
This trial looks at how well your body responds to extra fluids given through an IV, and whether it helps your veins. It is for people in the ICU who already have heart monitoring in place.
Guangzhou, GuangdongAges 18–99 - NCT07522580Recruiting
Heart Fluid Response Monitoring in Critically Ill Children
This study tests a simple, non-invasive device that measures how well a child's heart responds when doctors give extra fluids during intensive care. It helps doctors decide if more fluids will actually help the child feel better.
Le Plessis-Robinson, FranceAges birth–8 years - NCT07546656Recruiting
Using Vein Size to Predict Fluid Response in ICU Patients
This study tests whether measuring the size of a vein in your groin using ultrasound can help doctors decide if you need more fluids when you're critically ill in the ICU. The goal is to improve how doctors manage fluid treatment for patients on breathing machines.
Istanbul, IstanbulAges 18 years+ - NCT06593756Recruiting
Heart-Lung Support and Fluid Response Study
This study watches how your body responds to fluids while on VA ECMO (a heart-lung machine). The goal is to improve care for people needing this support.
ViennaAges 18–75 - NCT06593717Recruiting
Monitoring blood flow in VV-ECMO patients
This study tests how doctors can monitor your blood flow and fluid needs while you are on VV-ECMO. It involves a simple maneuver where your legs are raised to see if your heart needs more fluid.
ViennaAges 18–75 - NCT07009665Recruiting
Fluid management in sepsis patients at the emergency department
This study tests a personalized approach to giving fluids to patients with sepsis, a serious infection that can cause low blood pressure. The goal is to see if individualized fluid resuscitation improves outcomes compared to standard care.
Groningen, Provincie GroningenAges 18 years+ - NCT05369559RecruitingEarly Phase 1
Testing a small fluid dose in emergency low blood pressure
This early-phase study tests whether giving a very small fluid dose can quickly show who will benefit from fluids in the emergency department. It focuses on people with signs of low blood pressure and poor circulation.
MonastirAges 18–80 - NCT06492044Recruiting
Testing right heart strain to predict fluid response in septic shock
This study tests whether measuring the strain (stretch) of the right upper heart chamber with ultrasound can predict if a patient with septic shock will benefit from more fluids. Septic shock is a severe infection that causes very low blood pressure and organ damage.
AmiensAges 18 years+ - NCT07255469Recruiting
Fluid response test in children after heart surgery
This trial tests how well the body responds to a fluid bolus in children who have just had heart surgery. It uses blood gas tests and maybe an ultrasound to guide treatment.
Bron, FranceAges birth–15 years - NCT03431064Recruiting
Ultrasound test during surgery to predict fluid needs in children
This study looks at a specific breathing maneuver done while your child is on a ventilator during surgery, and uses ultrasound-related measurements to predict whether they’ll need extra fluids. If it works, it may help doctors give the right amount of fluid and avoid problems from too little or too much.
Boston, MassachusettsAges Up to 17 years - NCT06249568Recruiting
Testing fluid response during heart bypass surgery
This study tests a method to see if your body needs more fluids during heart bypass surgery. After the surgeon opens your chest, they will use a special breathing maneuver to check how well your heart responds to extra fluid, which may help guide your care.
AnkaraAges 18–80 - NCT07136532Recruiting
Predicting fluid needs in children with septic shock using ultrasound
This study tests whether using ultrasound of the neck (carotid artery) and heart can help doctors know which children with septic shock need more fluids. It aims to make fluid treatment safer and more precise in the pediatric intensive care unit (PICU).
CairoAges 1 month–16 years - NCT06180902Recruiting
Testing fluid response methods in patients with reduced consciousness
This trial compares different ways to check if a patient in the ICU with lowered consciousness needs more IV fluids. It aims to find the most accurate method, which could help doctors give the right amount of fluid.
MoscowAges 18 years+ - NCT05898269Recruiting
Predicting fluid needs while lying face down in ARDS
This study tests a way to predict whether you will benefit from a fluid bolus (a small amount of IV fluid) while you are lying face down for ARDS. It uses continuous heart monitoring to guide or evaluate fluid decisions and may help clinicians avoid too much or too little fluid.
Clermont-FerrandAges 18 years+ - NCT05888974Recruiting
Test of heart ultrasound to guide fluids in shock
This study checks whether a specific heart ultrasound measurement can help doctors decide if you will benefit from extra fluid during early emergency treatment for shock. It may help avoid unnecessary fluids and support faster, safer decision-making.
NîmesAges 18 years+ - NCT05185141Recruiting
Carotid ultrasound test to guide fluid during major abdominal surgery
This study uses a non-invasive ultrasound scan of the neck (carotid Doppler) to help predict whether you’ll benefit from extra IV fluids during major abdominal surgery. It aims to improve fluid management without placing extra invasive monitoring unless already planned.
Mainz, Rhineland-PalatinateAges 18–80 - NCT07494643Recruiting
Fluid response in children on low-tidal-volume ventilation
This study checks if giving fluids helps children on a ventilator with circulation problems. Doctors will use ultrasound to see how the heart responds to a small fluid boost.
AmiensAges birth–15 years - NCT04114799Recruiting
Tests brain-surgery monitoring to optimize circulation
This study checks a monitoring approach during brain tumor surgery to help control blood flow and heart-related measurements. It may benefit you by making surgery safer and helping the team respond faster during the operation.
Hradec KrálovéAges 18 years+ - NCT07298720Recruiting
Checking fluid needs with a light-based muscle test
This study uses a non-invasive light-based device on your arm muscle to see if you need more fluids. It aims to replace invasive monitoring for patients with arterial lines.
Sabadell, Spain/ BarcelonaAges 18 years+ - NCT07507877Recruiting
Ultrasound test to predict fluid needs in sepsis
This study uses an ultrasound to measure how much the axillary vein collapses when you breathe, to help doctors decide if you need more fluids. It is for patients with sepsis who are breathing on their own and have signs of low blood flow.
CairoAges 18 years+ - NCT07499401Recruiting
Fluid response test in ICU patients with vein congestion
This study looks at how tiny blood vessels respond to extra fluids in ICU patients who have vein congestion. It helps doctors understand if giving more fluid is helpful or harmful for you.
Ancona, ItalyAges 18 years+ - NCT07434713Recruiting
Testing early response to Eylea 8mg for wet AMD
This study looks at how quickly fluid in the retina clears after starting treatment with a higher dose of Eylea (aflibercept 8mg) for wet age-related macular degeneration (AMD). It aims to understand if early fluid changes can predict long-term outcomes.
BernAges 50 years+
Hear when a new Fluid Responsiveness trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for fluid responsiveness?
- Yes. Clin2 currently lists 26 recruiting fluid responsiveness studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a fluid responsiveness trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a fluid responsiveness trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.