Clinical trials
Chemotherapy clinical trials
Below are recruiting chemotherapy clinical trials, each written for real people, not researchers. We’re tracking 1,994 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06718309RecruitingPhase 2
Chemo and immunotherapy with targeted radiation before surgery for lung cancer
This trial tests giving chemotherapy, immunotherapy, and targeted radiation before surgery for people with non-small cell lung cancer that can be removed. The goal is to see if this combination shrinks tumors and improves outcomes.
Hangzhou, ZhejiangAges 18 years+ - NCT06730009RecruitingPhase 1/Phase 2
NK cell therapy after surgery for pancreatic or bile duct cancer
This trial tests whether adding natural killer (NK) cell therapy to standard chemotherapy after surgery can help prevent pancreatic or bile duct cancer from coming back. It is for patients who have had their tumor completely removed and are now ready for adjuvant chemotherapy.
TainanAges 18 years+ - NCT06731894RecruitingPhase 2
Cannabis for nerve pain after chemotherapy in breast and colon cancer survivors
This trial tests whether a cannabis-based product can reduce nerve damage (neuropathy) caused by chemotherapy in people who have finished treatment for breast or colon cancer. It focuses on survivors who still have pain, numbness, or tingling in their hands or feet.
Duarte, CaliforniaAges 18 years+ - NCT06735118Recruiting
Can AI help see chemo-related fatty liver?
This study uses a special MRI technique and artificial intelligence to see how chemotherapy may cause a fatty liver. It may help find liver changes early in people who have had chemo.
Kunming, YunnanAges 18–80 - NCT06737926Recruiting
Balance exercises for chemotherapy nerve damage in breast cancer
This study tests whether special balance and coordination exercises can help reduce nerve damage side effects (like numbness or tingling) caused by chemotherapy in breast cancer patients. You may benefit if you have these symptoms and want to improve your balance and movement.
Lahore, Punjab ProvinceAges 30–65 - NCT06742515RecruitingPhase 2
Blinatumomab with lower-dose chemo for B-ALL
This trial tests a combination of a targeted drug (blinatumomab) with a lower dose of standard chemotherapy for adults newly diagnosed with a certain type of B-cell acute lymphoblastic leukemia. The goal is to see if this approach is effective and causes fewer side effects than full-dose chemotherapy.
Hangzhou, ZhejiangAges 15–59 - NCT06746519RecruitingPhase 1/Phase 2
BN104 combined with chemotherapy or targeted therapy for AML
This clinical trial tests a new menin-blocking drug called BN104 in combination with chemotherapy or other targeted drugs for people with acute myeloid leukemia (AML) that has certain genetic changes. It may be an option if your AML is newly diagnosed or if you've already tried a menin inhibitor and it didn't work well enough.
Suzhou, JiangsuAges 18 years+ - NCT06749210RecruitingPhase 2
Balance training for nerve damage from chemotherapy
This trial tests a special exercise program (called balance training) to help breast cancer survivors who still have nerve damage and balance problems after finishing taxane chemotherapy. If you have tingling, numbness, or trouble staying steady, this study may help improve your balance and reduce fall risk.
New Haven, ConnecticutAges 40 years+ - NCT06755684RecruitingPhase 2
Pre-surgery targeted drug combo for EGFR-mutant lung cancer
This trial tests a new targeted pill (befotertinib) given before surgery, either with another targeted drug (bevacizumab) or with standard chemotherapy. The goal is to shrink the tumor and improve outcomes for people with a specific type of lung cancer.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06758544RecruitingPhase 1/Phase 2
VRT106 plus chemo for resectable pancreatic cancer
This trial tests a new drug called VRT106 combined with chemotherapy for people with pancreatic cancer that can be surgically removed. The goal is to see if the combination works better than standard treatment alone.
Guangzhou, GuangdongAges 18–75 - NCT06765616RecruitingPhase 2
Immunotherapy with chemo and radiation for rectal cancer before surgery
This trial tests a combination of a PD-L1 inhibitor (adebrelimab), short-course radiation, and chemotherapy given before surgery for locally advanced rectal cancer. The goal is to see if this approach can shrink the tumor and improve outcomes.
Jinan, ShandongAges 18–85 - NCT06769061Recruiting
Acupuncture for Chemo Nerve Pain in Gynecologic Cancers
This study tests whether acupuncture can help reduce nerve pain, numbness, or tingling in hands and feet caused by chemotherapy for gynecologic cancers. You may join if you finished certain chemo at least 3 months ago and still have these symptoms.
Hong KongAges 18 years+ - NCT06776757RecruitingPhase 1/Phase 2
Sintilimab plus cetuximab and chemo for first-line advanced colorectal cancer
This trial tests a combination of immunotherapy (sintilimab), a targeted therapy (cetuximab), and chemotherapy as a first treatment for advanced colorectal cancer that hasn't spread or come back after earlier treatment. It's for people whose tumors have certain genetic markers (RAS/BRAF wild-type) and show signs of immune activity (PD-L1 or CD8+ TILs).
Shenzhen, GuangdongAges 18–75 - NCT06799351RecruitingPhase 2/Phase 3
Gut bacteria and nerve pain after chemo
This study looks at how bacteria in your gut (microbiome) might be linked to nerve pain from chemotherapy. It is for people who are already in the OzoParQT trial and will provide a stool sample to help understand this connection.
Las Palmas, Las PalmasAges 18 years+ - NCT06802757RecruitingPhase 2
Study of posaconazole with immunotherapy and chemo for triple-negative breast cancer
This trial tests if adding posaconazole (an antifungal drug) to standard immunotherapy and chemotherapy before breast cancer surgery works better than just the standard treatment. It is for people with newly diagnosed, early-stage triple-negative breast cancer.
Jinan, ShandongAges 18–70 - NCT06816771RecruitingPhase 2
Pazopanib plus TGI/CIV for recurrent/refractory rhabdomyosarcoma in children
This trial tests a combination of two drugs (pazopanib and TGI/CIV) for children and teens whose rhabdomyosarcoma has come back or hasn't responded to standard treatment. The goal is to see if this combination can shrink tumors or slow the disease.
Jinan, ShandongAges 2–18 - NCT06831981Recruiting
Heat therapy with chemo and radiation for rectal cancer
This trial tests if adding heat therapy (hyperthermia) to standard chemotherapy and radiation helps treat rectal cancer that has high-risk features. Heat therapy is thought to make cancer cells more sensitive to treatment.
Tübingen, Baden-WurttembergAges 18 years+ - NCT06857292RecruitingPhase 2
A study of a new medicine to prevent fever in children on chemotherapy
This study tests a new medicine called Telpegfilgrastim to help prevent fever from low white blood cell counts in children (14–17) with certain cancers who are getting strong chemotherapy. It aims to see if the medicine is safe and works well.
Guangzhou, GuangdongAges 14–18 - NCT06859684RecruitingPhase 2
Triple therapy for advanced bile duct cancer of the liver
This trial tests a combination of three treatments for people with advanced bile duct cancer that cannot be removed by surgery or has spread. The treatments include a chemotherapy infusion directly into the liver artery (HAIC), an immunotherapy drug (durvalumab), and a targeted therapy pill (lenvatinib). It aims to see if this triple therapy can shrink or control the cancer better than standard treatments.
Chengdu, SichuanAges 18–75 - NCT06874933RecruitingPhase 2
Chemo plus anlotinib and benmelstobart for HR+/HER2- breast cancer
This trial tests adding anlotinib (a targeted therapy) and benmelstobart (an immunotherapy) to standard chemotherapy before surgery for a specific type of breast cancer. It may help shrink tumors and improve outcomes for patients whose tumors have certain markers.
Hangzhou, ZhejiangAges 18–75 - NCT06888063RecruitingPhase 2
Chemo pump into the liver for bile duct cancer that can be surgically removed
This trial tests whether giving extra chemotherapy directly to the liver through a small pump (called HAIP) before or after surgery can improve outcomes for patients with bile duct cancer inside the liver. It is for patients whose cancer is considered removable by surgery.
Rotterdam, South HollandAges 18 years+ - NCT06889623Recruiting
Chemotherapy right after surgery for high-risk bladder cancer
This trial tests whether giving chemotherapy immediately after surgery can help people with high-risk, non-muscle-invasive bladder cancer. It aims to reduce the chance of the cancer coming back.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06889688RecruitingPhase 3
New drug combo vs. chemo for advanced triple-negative breast cancer
This trial tests a new combination of three drugs (camrelizumab, apatinib, and eribulin) against the standard chemotherapy chosen by your doctor. It's for people with advanced triple-negative breast cancer that has gotten worse after previous treatments.
Guangzhou, GuangdongAges 18–70 - NCT06906887RecruitingPhase 2
Pulsed low-dose radiation vs standard chemoradiation for esophageal cancer
This trial compares a new way of giving radiation (in short, pulsed low-dose bursts) to the standard method, both combined with chemotherapy, for people with esophageal cancer. It aims to see if the pulsed approach is safer and equally effective.
Milwaukee, WisconsinAges 18 years+
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Common questions
- Are there clinical trials for chemotherapy?
- Yes. Clin2 currently lists 1,994 recruiting chemotherapy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chemotherapy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chemotherapy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.