Clinical trials · Ohio
Children clinical trials in Ohio
We’re tracking 317 recruiting children studies with a site in Ohio — including Phase 1, Phase 1/Phase 2, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in Ohio
- NCT04181138Recruiting
Study of childhood primary sclerosing cholangitis types
This study follows children and young adults with primary sclerosing cholangitis (PSC) to understand the condition and how it shows up on scans or biopsy. It may help doctors better recognize PSC and choose the best next steps for care.
Cincinnati, OhioAges 2–25 - NCT04216927RecruitingPhase 3
Neonates on heart-lung bypass get NO to prevent kidney injury
This Phase 3 study tests whether not giving nitric oxide during heart-lung bypass in newborns helps reduce the risk of acute kidney injury. It focuses on newborns having heart surgery for congenital heart disease.
Cincinnati, OhioAges 1 day–1 month - NCT04195347RecruitingPhase 1/Phase 2
CM4620 to lessen pancreatitis after asparaginase
This study tests CM4620 to reduce how severe pancreatitis becomes in children and young people with leukemia/lymphoma who develop pancreatitis after receiving a drug called asparaginase. It aims to improve outcomes by calming the inflammation of the pancreas.
Cincinnati, OhioAges Up to 21 years - NCT04098445Recruiting
Study of lung injury in children after stem cell transplant
This study follows children and teens who get a stem cell transplant to learn how lung problems develop over time. Your participation could help doctors better predict, prevent, and manage lung injury after transplant.
Cincinnati, OhioAges Up to 24 years - NCT04093986Recruiting
Using past pregnancy records from women with sickle cell
This study looks back at past pregnancy and breastfeeding experiences in women with sickle cell disease who took hydroxyurea. It aims to better understand how hydroxyurea exposure may affect pregnancy and baby outcomes.
Cincinnati, OhioAges Any age - NCT03959085RecruitingPhase 3
Inotuzumab plus chemotherapy for high-risk childhood leukemia
This Phase 3 trial tests whether adding inotuzumab to standard post-induction chemotherapy improves outcomes for children and young teens with high-risk B-ALL, mixed phenotype acute leukemia (MPAL), or certain high-risk B-LLy. It may help by targeting leukemia cells more directly, but participation depends on specific age, lab results, and medical history rules.
Cleveland, OhioAges 12 months–25 years - NCT03826992RecruitingPhase 1
Study drug Venetoclax plus Vyxeos for hard-to-treat leukemia
This Phase 1 study tests whether a combination of venetoclax and Vyxeos can treat children and young adults with certain relapsed or treatment-resistant acute leukemias. It may help shrink the leukemia or improve blood counts when standard treatments have not worked.
Cincinnati, OhioAges 1–39 - NCT03862274Enrolling by invitation
Study of development in children with CLN2 due to TPP1 changes
This study looks at how children’s development progresses in CLN2 disease caused by a specific enzyme problem (TPP1). It may help doctors better understand outcomes and guide future care for children with this diagnosis.
Columbus, OhioAges Any age - NCT03587272RecruitingPhase 2
Sibling bone marrow transplant to reduce treatment side effects
This study tests a way to do a bone marrow (stem cell) transplant from an HLA-matched sibling in children with sickle cell disease, aiming to lower the risk of serious side effects. You may be considered if you have certain past sickle complications and your body can safely handle the transplant plan.
Columbus, OhioAges 2–25 - NCT03541785Enrolling by invitation
Using NGAL to guide fluids and start kidney-filtering in children
This study tests whether measuring a urine protein called NGAL can help doctors choose the right fluid amount and decide when to start a kidney-filtering treatment called CRRT in critically ill children with kidney injury. If it works, it may help treat kidney problems sooner and more safely.
Cincinnati, OhioAges 3 months–25 years - NCT03067181RecruitingPhase 3
Active surveillance and chemotherapy for germ cell tumors
This study looks at how to manage germ cell tumors in children and young adults using careful monitoring for some patients and chemotherapy for others. It aims to see whether these approaches can control the cancer while avoiding unnecessary treatment when possible.
Marysville, OhioAges Any age - NCT03126916RecruitingPhase 3
Testing added therapy for high-risk neuroblastoma in children
This Phase 3 study tests whether adding either a targeted drug (lorlatinib) or a radioactive treatment (131I-MIBG) to intensive chemotherapy improves outcomes for children with high-risk neuroblastoma. It may help by aiming at tumor cells more directly alongside standard treatment.
Cleveland, OhioAges 12 months–30 years - NCT03175471Recruiting
MRI study of blood-vessel and tissue signs in child liver disease
This trial uses MRI scans to look for “biomarkers,” which are measurable signs in the liver, to better understand autoimmune liver diseases in children and teens. It may help doctors track disease and improve care by finding imaging patterns linked to illness.
Cincinnati, OhioAges 6–23 - NCT03178630Recruiting
MRI scans to track outcomes in children with autoimmune liver disease
This study uses MRI scans to find “biomarkers,” or imaging clues, that may help predict how autoimmune liver conditions will progress in children and young adults. If you qualify, you may get MRI imaging to see whether it relates to future health outcomes.
Cincinnati, OhioAges 6–23 - NCT02964494Recruiting
Congenital anemia registry for congenital dyserythropoietic anemia
This study is a registry that collects medical and lab information from people with congenital dyserythropoietic anemia (CDA), a lifelong type of anemia that can cause jaundice. It helps doctors better understand the condition and its causes, including in families where it runs.
Cincinnati, OhioAges Any age - NCT02402244Recruiting
Caring registry study for children and young people with cancer
This study keeps a careful record of children, teens, and young adults with cancer (and some related growths) and may follow them over time. It helps researchers better track outcomes and future contact so care can improve.
Cleveland, OhioAges Up to 25 years - NCT02461615Recruiting
Registry for pulmonary alveolar proteinosis (PAP) patients
This study keeps a national record of people with pulmonary alveolar proteinosis (PAP). It includes one “snapshot” group and one group that follows people with autoimmune PAP and asks about symptoms and quality of life.
Cincinnati, OhioAges Any age - NCT02316379RecruitingPhase 1/Phase 2
Breathing MRI test to map lung airspaces in adults
This early trial uses a special “breathing” MRI scan to create a detailed picture of how air moves in the lungs. It’s mainly a calibration study to set up the scan correctly, and you may help improve the test for future use.
Cincinnati, OhioAges 18 years+ - NCT02532452RecruitingPhase 2
T-cells made to fight a specific virus
This Phase 2 study gives you special “virus-targeting” immune cells (T-cells) to help your body control a current viral infection or virus that has come back (reactivated). It may help reduce the virus activity while you are immunocompromised, meaning your immune system is weaker than usual.
Columbus, OhioAges 2 days+ - NCT02235857Recruiting
Device treatment study for children with focal segmental kidney scarring
This trial studies a medical device (the Liposorber LA-15) in children with focal segmental glomerulosclerosis (FSGS), a kidney condition that can cause heavy protein loss in the urine. It may help by improving disease control when standard treatments have not worked, were hard to tolerate, or can’t be used.
Akron, OhioAges Up to 21 years - NCT01790152Recruiting
Dexrazoxane study to monitor heart damage in cancer survivors
This study tests dexrazoxane (DRZ) to see how it affects blood and heart-related “biomarkers,” or measurable signs of heart damage, after cancer treatment. It mainly targets survivors who may be at risk for cardiomyopathy (heart muscle weakness) or related heart failure.
Akron, OhioAges Any age - NCT02040714Enrolling by invitation
Study of current treatments for Perthes hip disease
This study follows children (and teens) with Legg-Calvé-Perthes disease to learn about how today’s treatments work in real life. It may help doctors choose the best next steps for your child’s hip health.
Cincinnati, OhioAges 1–18 - NCT01401998Recruiting
Study collecting information from people with ARPKD
This study looks at medical records, imaging, and genetic testing for people with autosomal recessive polycystic kidney disease (ARPKD). It may help researchers better understand the condition and how it affects the liver and kidneys.
Cincinnati, OhioAges Up to 18 years - NCT02048332RecruitingPhase 1/Phase 2
Donor immune cells for preventing infections after stem cell transplant
This trial studies donor-made immune cells (T-cells) given after a stem cell transplant to help your body fight infections. It aims to test how safe the treatment is and whether it supports the immune system in the months after transplant.
Akron, OhioAges 4 weeks+
Where these studies are running in Ohio
Institutions with a site for the recruiting children studies listed above.
- Cincinnati Children's Hospital Medical Center · 18 studies
- Nationwide Children's Hospital · 7 studies
- Children's Hospital Medical Center of Akron · 4 studies
- Cleveland Clinic Foundation · 4 studies
- Dayton Children's Hospital · 4 studies
- ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital · 4 studies
- Rainbow Babies and Children's Hospital · 4 studies
- Akron Children's Hospital · 3 studies
What taking part in a children study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Children trials in other states
Common questions
- Are there children clinical trials in Ohio?
- Yes. We're currently tracking 317 recruiting children studies with a site in Ohio, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a children study in Ohio?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Ohio to take part?
- Not necessarily. These studies have a site in Ohio, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a children trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New children studies open in Ohio regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.