Clinical trials
Cholangiocarcinoma clinical trials
Below are recruiting cholangiocarcinoma clinical trials, each written for real people, not researchers. We’re tracking 185 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06735560Recruiting
PET scan with a tracer for liver, bile duct, or neuroendocrine tumors
This trial uses a special PET scan tracer (zirconium-labelled girentuximab) to see if it can find and track certain liver, bile duct, and pancreatic/intestinal neuroendocrine tumors. It may help doctors better understand your cancer and guide treatment decisions.
NantesAges 18 years+ - NCT06774690Recruiting
Arterial treatments for primary liver cancer
This study is watching how treatments that deliver medicine or tiny beads directly into the liver's blood supply work for people with liver cancer. If you have liver cancer and are getting or have gotten one of these treatments, this study wants to learn from your experience.
BolognaAges 18 years+ - NCT06801899Recruiting
Total vs. partial Whipple for high-risk pancreatic cancer
This trial compares removing the entire pancreas (total pancreatectomy) versus removing only the head (standard Whipple) for certain cancers of the pancreas, bile duct, or ampulla. It is for people whose surgeon thinks the pancreas connection after surgery is likely to leak, which can cause serious complications.
MünsterAges 18 years+ - NCT06840886RecruitingPhase 1
Testing a new drug for advanced solid tumors
This study tests an experimental drug called PHST001 for people with advanced solid tumors that have stopped responding to standard treatments. The goal is to see if it is safe and if it can help shrink tumors.
Beverly Hills, CaliforniaAges 18 years+ - NCT06851663RecruitingPhase 2/Phase 3
New PET scan for many solid tumors
This trial tests a new type of PET scan that uses a special antibody to find a marker called Trop2 on many common solid tumors. It may help doctors see tumors more clearly without needing a biopsy.
ShanghaiAges 18–75 - NCT06862934Recruiting
Liver transplant for bile duct cancer that can't be removed
This study tests if a liver transplant can help people with a type of bile duct cancer (intrahepatic cholangiocarcinoma) that cannot be surgically removed. It is for patients whose cancer has been stable for at least 6 months after initial treatments.
Milan, MilanAges 18–70 - NCT06864195Recruiting
Breath test for liver cancer detection
This study tests a simple breath test to detect liver cancer and monitor liver health. It is looking for patients with liver cancer, liver cirrhosis, primary sclerosing cholangitis, or people with normal livers to see if the breath test can help tell the difference.
LondonAges 18 years+ - NCT06877637Recruiting
Tracking bile duct and liver cancer during treatment
This study tracks how bile duct and liver cancers change during treatment, to help doctors find the best therapies for patients. It is for people who are newly diagnosed or starting a new treatment.
KristianstadAges 18 years+ - NCT06899152Recruiting
New tests to track liver health during radiation for liver cancer
This study tests new blood tests and MRI scans to see how well your liver works during radiation therapy for liver cancer. It may help doctors better plan treatment and monitor your liver health.
The Bronx, New YorkAges 18 years+ - NCT06899854Recruiting
Collecting blood and tissue from patients with liver cancer
This study collects blood and tumor tissue samples from people with primary liver cancer who are starting their first treatment (systemic therapy or surgery). The samples help researchers learn more about these cancers and how to improve future treatments.
Pavia, PaviaAges 18–90 - NCT06914648Recruiting
Liver preparation before surgery study for certain liver cancers
This study tests a procedure called portal vein embolization (PVE) to help grow the healthy part of the liver before surgery. It may be an option for people with certain liver cancers who need more healthy liver tissue before their operation.
New Haven, ConnecticutAges 18 years+ - NCT06925516RecruitingPhase 2
Apatinib plus immunotherapy and chemo for unresectable bile duct cancer
This study tests a combination of two drugs (apatinib and adebrelimab) with standard chemotherapy for people with bile duct cancer that cannot be removed surgically. The goal is to see if this combination works better than chemotherapy alone.
Guangzhou, GuangdongAges 18–75 - NCT06971848Recruiting
Skin testing for biologic drug allergies
This trial checks if people can safely receive certain biologic drugs without allergic reactions, using skin tests to see how the body reacts. It may help find out if you are allergic to a biologic medicine you have taken before.
AngersAges 18 years+ - NCT07025174RecruitingPhase 2
Sequential anti-angiogenic therapy after immunotherapy for advanced bile duct cancer
This trial tests whether giving a drug that blocks blood vessel growth (anti-angiogenic therapy) after immunotherapy can help people with advanced bile duct, gallbladder, or cholangiocarcinoma that cannot be removed by surgery. The goal is to see if this sequence improves outcomes for patients who have not had prior treatment for advanced disease.
Hangzhou, ZhejiangAges 18–75 - NCT07043387Recruiting
Simplified radioembolization for liver cancer and bile duct cancer
This trial tests a streamlined way to deliver radioactive beads (radioembolization) directly to liver tumors in people with metastatic liver cancer or bile duct cancer. It aims to make treatment simpler and safer while still effectively targeting tumors.
Goyang-siAges 19 years+ - NCT07101237Recruiting
Precision diagnosis and treatment study for liver cancer
This study aims to improve how doctors diagnose and treat liver cancer by combining advanced imaging tests and genetic analysis. It may help in choosing the most effective treatment for each person.
BeijingAges 18–70 - NCT07106827RecruitingPhase 1
Study of a new drug for advanced or resistant solid tumors
This trial tests a new drug, GV20-0251, for people with advanced solid tumors that have not responded to standard treatments. It aims to see if the drug is safe and helpful.
Chengdu, SichuanAges 18 years+ - NCT07146646RecruitingPhase 2
Chemo combo for advanced bile duct cancer
This trial tests a combination of two chemotherapy drugs (trifluridine/tipiracil and oxaliplatin) for people with advanced or metastatic bile duct cancer (including gallbladder cancer) who have only had one prior treatment. The goal is to see if this combination can help control the cancer.
Cleveland, OhioAges 19 years+ - NCT07155525RecruitingPhase 3
Glue to prevent leaks after pancreas surgery
This trial tests whether a special medical glue (Glubran® 2) applied to the pancreas during surgery can help prevent fluid leaks. It is for people undergoing a Whipple procedure for pancreatic cancer who have a soft pancreas.
Minya, Minya GovernorateAges 18–75 - NCT07201519RecruitingPhase 2
Chemo infusion for liver cancer using a hybrid care model
This trial tests a special type of chemotherapy (hepatic artery infusion) for people with cancers that have spread to the liver, such as colorectal cancer or bile duct cancer (intrahepatic cholangiocarcinoma). It studies whether delivering this treatment partly at a community center and partly at a university hospital is safe and feasible.
Lexington, KentuckyAges 18–99 - NCT07213791RecruitingPhase 1
Study of a new drug for FAP-positive cancers
This trial tests a new drug (LY4337713) for cancers that have a specific protein called FAP on their surface. It may be an option for people whose cancer has continued to grow after standard treatments.
Newport Beach, CaliforniaAges 18 years+ - NCT07223307RecruitingPhase 2
MRI-guided radiation for liver cancers
This trial tests a precise MRI-guided radiation treatment for liver cancers, including liver cancer, bile duct cancer, or cancer that has spread to the liver. The goal is to target tumors more accurately while protecting healthy tissue.
Palo Alto, CaliforniaAges 18 years+ - NCT07169734RecruitingPhase 1/Phase 2
ALE.P03 for advanced CLDN1-positive solid tumors
This trial tests a new drug, ALE.P03, for people with advanced or metastatic solid tumors that have a certain protein (CLDN1). The drug is given alone (monotherapy) to see if it can shrink tumors or slow their growth.
Phoenix, ArizonaAges 18 years+ - NCT07263217Recruiting
Spirulina for liver protection after bile duct cancer surgery
This trial tests whether spirulina (a type of algae) can help protect the liver and aid recovery after surgery for bile duct cancer. Participants will take spirulina or a placebo before and after a planned liver resection.
HangzhouAges 18–75
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Common questions
- Are there clinical trials for cholangiocarcinoma?
- Yes. Clin2 currently lists 185 recruiting cholangiocarcinoma studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cholangiocarcinoma trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cholangiocarcinoma trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.