Clinical trials
Chronic Diseases in Children clinical trials
Below are recruiting chronic diseases in children clinical trials, each written for real people, not researchers. We’re tracking 156 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04461821Recruiting
Breath test to study disease in children
This study uses a special machine to analyze exhaled breath to learn about different illnesses in children and teens. It may help researchers find breathing “signals” that reflect conditions like breathing problems, nervous system issues, or new/worsening type 1 diabetes.
BaselAges Up to 22 years - NCT07582549RecruitingPhase 3
Treatment for children's persistent cough
This Finnish study tests whether two common medicines (a steroid inhaler and an antibiotic) can help children whose cough has lasted more than 4 weeks without an obvious cause. Researchers want to see if these treatments work better than doing nothing.
TampereAges 1–6 - NCT07425574Recruiting
Study on how Stargardt eye conditions progress in children and adults
This study observes how Stargardt disease and similar eye conditions change over time in children and adults. It aims to learn more about the disease progression to help develop future treatments.
Phoenix, ArizonaAges 6 years+ - NCT06442761RecruitingPhase 1
Stem cell collection for sickle cell disease using motixafortide
This trial tests a drug called motixafortide that helps move stem cells from your bone marrow into your blood so they can be collected for future gene therapy. It is for adults with severe sickle cell disease who may benefit from this treatment approach.
Birmingham, AlabamaAges 18 years+ - NCT05021029Enrolling by invitation
Observational study of pre-cancerous stomach conditions
This study follows patients with pre-cancerous stomach conditions to learn more about how they progress. By collecting health information over time, researchers hope to improve early detection and treatment of stomach cancer.
Sacramento, CaliforniaAges 18 years+ - NCT07024199RecruitingPhase 4
Pain relief for children with acute pancreatitis
This trial compares three common pain relievers (paracetamol, ibuprofen, and metamizole) to see which works best for children with acute pancreatitis. It aims to help your child feel better faster with fewer side effects.
WarsawAges 3–18 - NCT04414046RecruitingPhase 2
Stem cell transplant using T-cell cleanup for immune and metabolism disorders
This Phase 2 study tests a specialized stem cell transplant that removes certain “T-cells” (a type of immune cell) to treat children with serious immune system or inherited metabolic problems. The goal is to improve or stabilize disease by resetting the immune system and supporting the body’s function.
St. Petersburg, FloridaAges Up to 21 years - NCT07247188RecruitingPhase 3
Pneumococcal vaccine study for children with sickle cell disease
This trial tests a single dose of a new pneumococcal vaccine (21-valent) in children and teens with sickle cell disease. It aims to see if the vaccine can help protect against serious infections caused by pneumococcus bacteria, which are especially dangerous for people with SCD.
Atlanta, GeorgiaAges 2–17 - NCT04166526Recruiting
Brain and brain-vessel MRI study in kids with sickle cell
This study uses MRI scans to understand how the brain and blood vessels are affected in children with sickle cell disease, including before and after certain treatments. It also includes healthy children for comparison and may help improve future monitoring and care.
Boston, MassachusettsAges 8–18 - NCT04925375RecruitingPhase 2
Abatacept for children with CVID and lung scarring
This Phase 2 trial tests abatacept to improve a specific type of lung disease in children with common variable immunodeficiency (CVID). It aims to slow or reduce ongoing lung changes seen on CT scans while they continue their usual immune “replacement” therapy.
San Francisco, CaliforniaAges 4 years+ - NCT03175471Recruiting
MRI study of blood-vessel and tissue signs in child liver disease
This trial uses MRI scans to look for “biomarkers,” which are measurable signs in the liver, to better understand autoimmune liver diseases in children and teens. It may help doctors track disease and improve care by finding imaging patterns linked to illness.
Cincinnati, OhioAges 6–23 - NCT03178630Recruiting
MRI scans to track outcomes in children with autoimmune liver disease
This study uses MRI scans to find “biomarkers,” or imaging clues, that may help predict how autoimmune liver conditions will progress in children and young adults. If you qualify, you may get MRI imaging to see whether it relates to future health outcomes.
Cincinnati, OhioAges 6–23 - NCT05311436Recruiting
Nutrition program study for slum residents in Dhaka
This study tests a nutrition program for pregnant women, adolescent girls, and young children living in Dhaka slums. It is designed to support healthier nutrition during a key growth or pregnancy period.
Dhaka, Dhaka DivisionAges 1 day–39 years - NCT04249830Recruiting
Donor stem cell transplant after donor cell targeting in youth
This trial studies a special donor stem cell transplant where the donor’s immune cells are reduced, aiming to lower harmful immune attacks after transplant. It may help children and young adults with certain high-risk blood cancers or rare bone marrow disorders.
Palo Alto, CaliforniaAges 1 month–60 years - NCT06560879Enrolling by invitationPhase 2
Probiotics to prevent stomach problems in children with leukemia
This trial tests whether probiotics can help prevent stomach and gut side effects from chemotherapy in children with leukemia. If your child is between 6 and 17, in the right phase of treatment, and doesn't have any major gut issues, they may be eligible.
Mexico City, CoyoacanAges 6–17 - NCT06443502RecruitingPhase 3
Vedolizumab for children with chronic pouchitis
This study tests a medicine called vedolizumab to see if it is safe and helps children and teenagers with chronic pouchitis (inflammation in the pouch after colon removal). It is for kids who have not had good results with other treatments.
Leuven, Vlaams-BrabantAges 2–17 - NCT07252050RecruitingPhase 1/Phase 2
Ruxolitinib and half-matched transplant for severe sickle cell disease
This trial tests a new approach using the drug ruxolitinib to help a half-matched bone marrow transplant work better for people with severe sickle cell disease. It aims to reduce complications and improve outcomes.
Aurora, ColoradoAges 12–45 - NCT07780331Recruiting
Virtual reality and games to reduce fear in children using inhalers
This study tests whether using virtual reality glasses or playing games on a tablet can help reduce fear and anxiety in young children (aged 4-6) when they need to take medication through an inhaler or nebulizer. It aims to see if these distractions make the experience more comfortable.
Balıkesir, BalıkesirAges 4–6 - NCT07405333Recruiting
Coughing exercises vs breathing device after heart surgery in children
This study compares simple coughing exercises with a breathing device (incentive spirometry) to help children recover lung function faster after heart surgery. It may help reduce complications and shorten hospital stays.
Baghdad, Baghdad GovernorateAges 6–18 - NCT07167927Recruiting
Decision support tool for children with neuromuscular scoliosis
Researchers are developing a decision support tool to help parents and doctors make decisions about surgery for children with neuromuscular scoliosis. The tool aims to provide clear information and support during the consultation.
Los Angeles, CaliforniaAges 8 years+ - NCT07170085Recruiting
Positioning for babies with breathing problems
This trial tests if different body positions help babies under 1 year old with breathing problems breathe better while on oxygen support (High-Flow or CPAP).
OdenseAges Up to 1 year - NCT04791748Recruiting
Virtual reality balance training for kids with inner-ear problems
This study uses virtual reality tasks to understand and compare balance and movement in children with long-term inner-ear (vestibular) problems versus those without. It may help doctors learn what supports best balance and safety during daily activities.
ParisAges 7 years+ - NCT05505500Recruiting
Parent and patient interviews for childhood kidney swelling
This study uses interviews to understand how swelling from nephrotic syndrome affects daily life for children and their caregivers. It may help researchers design better care by capturing the patient and parent perspective.
Ann Arbor, MichiganAges 2 years+ - NCT07602595Recruiting
Early-life health risks and chronic pain in teens and young adults
This study looks at how early health problems might affect pain that lasts a long time. If you had a muscle or joint surgery, or a rheumatic disease, before age 18, you might help us understand why some people get ongoing pain.
Cincinnati, OhioAges 14–26
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Common questions
- Are there clinical trials for chronic diseases in children?
- Yes. Clin2 currently lists 156 recruiting chronic diseases in children studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic diseases in children trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic diseases in children trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.