Clinical trials
Chronic Kidney Disease Stage 5 clinical trials
Below are recruiting chronic kidney disease stage 5 clinical trials, each written for real people, not researchers. We’re tracking 137 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07380113RecruitingPhase 4
Comparing two drugs for sleep in dialysis patients with itch
This trial tests if anrikefon or nalfurafine improves sleep quality in people on hemodialysis who have chronic kidney disease-related itching. It aims to find a better treatment for both itch and sleep problems.
Guangzhou, GuangdongAges 18–75 - NCT07385651Recruiting
Cool storage for donated kidneys
This trial compares storing donated kidneys at 10 degrees Celsius (a cooler temperature) instead of the usual ice storage. It tests if this might help the kidney stay healthier before transplant.
Nashville, TennesseeAges 18 years+ - NCT07358572Recruiting
Eye-brain-kidney study in chronic kidney disease
This study is looking at how chronic kidney disease (CKD) affects the eyes, brain, and kidneys. It uses MRI scans to examine these organs, and aims to find connections that could help improve care for people with CKD.
Beijing, Beijing MunicipalityAges 18–70 - NCT06897605RecruitingPhase 2
Dapagliflozin for anemia in kidney disease
This trial tests whether a medication called dapagliflozin can help improve anemia in people with chronic kidney disease. If you have moderate to severe kidney disease and low red blood cell counts despite taking standard anemia treatment, this study may explore a new option.
Al MansurahAges 18 years+ - NCT07231679RecruitingPhase 1/Phase 2
Study of IGT-303 for diabetic kidney disease
This study tests an investigational drug called IGT-303 in people with chronic kidney disease caused by type 2 diabetes. It aims to see if the drug is safe and helpful for slowing kidney damage.
Chula Vista, CaliforniaAges 18–75 - NCT07187713RecruitingPhase 4
Study of ACE Reno, Pico Cell Matrix for kidney health
This trial tests a new treatment called ACE Reno, Pico Cell Matrix to see if it can improve kidney function in people with chronic kidney disease (CKD) at various stages. It may be an option if you have early to moderate kidney issues (including after a transplant) and are already on standard therapies.
Giza, GZAges 18–80 - NCT07187479Recruiting
Testing a new insulin approach for kidney disease and diabetes
This study tests a new approach to help your body use insulin better, which may improve blood sugar control and slow down kidney disease. It is for people with advanced chronic kidney disease and type 2 diabetes who are not yet on dialysis.
Phoenix, ArizonaAges 18 years+ - NCT07186218Recruiting
Symptom monitoring with feedback for advanced kidney disease
This study tests a symptom-monitoring system with feedback for people with advanced chronic kidney disease (CKD). The goal is to help manage symptoms and improve quality of life without needing dialysis or a transplant right away.
Boston, MassachusettsAges 18 years+ - NCT07153939Recruiting
Study of a new device to create dialysis access
This trial tests a new device called the Velocity pAVF System that creates a connection between a vein and artery in your arm for hemodialysis. If you need dialysis now or within the next 6 months, this could be a new option for you.
Dothan, AlabamaAges 18–80 - NCT07151742Enrolling by invitation
Exercise during dialysis for muscle health
This study tests whether exercise during hemodialysis can improve muscle oxygen levels and how well dialysis works. It is for people who have been on dialysis for at least a year and have muscle loss (sarcopenia).
Istanbul, KadikoyAges 18–65 - NCT07123909Recruiting
Immune adsorbent therapy for dialysis patients with inflammation
This study tests a therapy that absorbs inflammatory substances from the blood during dialysis. It may help people on dialysis who have ongoing inflammation, shown by high IL-6 or CRP levels.
MoscowAges 18 years+ - NCT07107919Recruiting
Imaging heart and kidney health in chronic kidney disease
This study uses advanced imaging (PET/MRI) to look at how kidney disease affects the heart and blood vessels. It may help doctors better understand and treat chronic kidney disease.
Qingdao, ShandongAges 18–80 - NCT07105670Recruiting
Replacing high-protein foods in chronic kidney disease
This study looks at how replacing high-protein foods affects people with chronic kidney disease. If you join, you will eat a carefully controlled diet to help researchers understand if changing your protein intake can improve your kidney health.
West Lafayette, IndianaAges 40–70 - NCT06982079RecruitingPhase 3
SGLT2 inhibitors for advanced kidney disease
This trial tests whether SGLT2 inhibitor drugs can protect kidney function in people with advanced chronic kidney disease who are not yet on dialysis. It may help slow further kidney decline.
CairoAges 18 years+ - NCT07017270RecruitingPhase 4
GLP-1 drugs for people with diabetes on dialysis
This study tests if a type 2 diabetes medication called a GLP-1 receptor agonist (like Ozempic) is safe and effective for people on dialysis. It may help manage blood sugar and improve health outcomes for those with kidney failure.
Toronto, OntarioAges 18 years+ - NCT05149196Recruiting
Goal-directed fluid and blood pressure plan after kidney surgery
This trial tests a carefully tailored plan for managing blood pressure and fluid during and after kidney removal surgery, to help reduce kidney injury after surgery. It may be especially helpful if you’re having one kidney removed for cancer and your baseline heart/kidney risk is not too high.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06971874Recruiting
Sleep apnea and kidney disease: A study on outcomes
This trial looks at how obstructive sleep apnea affects people with chronic kidney disease (stages 3-4). It aims to help understand the connection between these conditions and guide better care.
Guangzhou, GuangdongAges 18–75 - NCT05942027RecruitingPhase 4
CoQ10 in early-to-moderate kidney disease with high urine protein
This study tests whether taking coenzyme Q10 can improve chronic kidney disease in adults with moderate kidney function and higher urine protein. It also looks at safety, especially for blood pressure and potassium levels.
Tanta, Capital of Gharbia Governorate.Ages 18 years+ - NCT05942053RecruitingPhase 4
Vitamin K2 for chronic kidney disease with high urine protein
This trial studies whether vitamin K2 can help people with chronic kidney disease (kidney damage that lasts months or longer), especially those with higher protein levels in the urine. It compares vitamin K2 use in a specific group and watches kidney-related health outcomes and safety.
Tanta, Capital of Gharbia Governorate.Ages 18 years+ - NCT06901960Recruiting
Monitoring high potassium with a smart ECG device in kidney disease
This trial tests if a portable ECG device can help detect high potassium levels early in people with moderate to severe chronic kidney disease. It aims to make monitoring easier without frequent blood tests.
Beijing, Beijing MunicipalityAges 18–99 - NCT06799936Recruiting
Helping older adults with kidney disease make treatment choices
This study tests a program that helps older adults with advanced chronic kidney disease talk with their doctors about treatment options, like dialysis, palliative care, or a kidney transplant. It aims to make sure patients' values and preferences are heard in these important decisions.
Hong KongAges 65 years+ - NCT06725810RecruitingPhase 4
Enarodustat for anemia in chronic kidney disease (not on dialysis)
This trial tests enarodustat, a pill for anemia, in people with chronic kidney disease who are not on dialysis. It aims to see if it can safely raise hemoglobin levels.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06741072RecruitingPhase 1
Vaccine to prevent EBV-related cancer in transplant patients
This trial tests a vaccine (OSU-2131) that may help prevent cancers caused by the Epstein-Barr virus in people waiting for an organ transplant. The vaccine is designed to train your immune system to fight the virus.
Columbus, OhioAges 18–65 - NCT06721143RecruitingPhase 1/Phase 2
Study of AION-301 for chronic kidney disease
This trial tests an experimental drug called AION-301 for people with chronic kidney disease (CKD). The goal is to see if it's safe and may help slow kidney decline. It's given by IV infusion and compared to a placebo (inactive infusion).
Miami, FloridaAges 35–75
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Common questions
- Are there clinical trials for chronic kidney disease stage 5?
- Yes. Clin2 currently lists 137 recruiting chronic kidney disease stage 5 studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic kidney disease stage 5 trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic kidney disease stage 5 trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.