Clinical trials
Chronic Liver Disease clinical trials
Below are recruiting chronic liver disease clinical trials, each written for real people, not researchers. We’re tracking 388 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05677971RecruitingPhase 3
Tested medicine to treat liver scarring in PiZZ alpha-1 disease
This Phase 3 study tests fazirsiran for safety and whether it can help people with a specific genetic form of alpha-1 antitrypsin–related liver disease that causes liver scarring. You may be eligible if you have the PiZZ genetic type and moderate-to-severe fibrosis, with certain lung and liver conditions ruled out.
Birmingham, AlabamaAges 18–75 - NCT05305287RecruitingPhase 4
Measuring liver energy use in people with diabetes and fatty liver disease
This study looks at how the liver uses energy (mitochondria) in people with type 2 diabetes and fatty liver disease. By understanding this, researchers may find better ways to treat liver problems.
San Antonio, TexasAges 18–80 - NCT04781322RecruitingPhase 1
Study drug to reduce LDL cholesterol effects in heavy drinkers
This Phase 1 study tests how safe a cholesterol-lowering antibody (alirocumab) is in people who drink heavily but are not seeking alcohol treatment. It also looks at early drug effects in the body to see how it might change cholesterol-related signals.
Bethesda, MarylandAges 21–65 - NCT04634643Recruiting
Studies what causes fatty liver in teens
This study looks at why “nonalcoholic fatty liver disease” happens in teenagers and how it develops. It may help doctors better predict and prevent liver problems in children, even if there isn’t a new drug for you to take.
New Haven, ConnecticutAges 12–18 - NCT03855917RecruitingPhase 4
Short 4-week hepatitis C treatment for early liver disease
This trial tests whether a very short 4-week course of two hepatitis C drugs (sofosbuvir and glecaprevir-pibrentasvir) can cure hepatitis C in people with early-stage liver disease. The goal is to see if a shorter treatment works as well as longer ones.
Darlinghurst, New South WalesAges 18 years+ - NCT03572465Recruiting
Ultrasound tests to diagnose fatty liver inflammation
This study checks whether special ultrasound measurements can help diagnose nonalcoholic steatohepatitis (NASH), a type of fatty liver disease. You may need a liver biopsy as part of routine care, and you may also be scanned with MRI to support the study tests.
Montreal, QuebecAges 18 years+ - NCT03151473Recruiting
Study of adults with fatty liver and NASH over time
This is a long-term study that follows adults who are being managed for fatty liver (NAFL) or NASH to learn how these conditions change over time. It may help researchers better understand what to expect and how care decisions could be improved.
Hong KongAges 18 years+ - NCT03224949Recruiting
Study comparing fatty liver types and healthy livers
This study compares liver samples and blood tests from people with alcohol-related fatty liver disease, alcohol-related hepatitis, and cirrhosis (including some with liver cancer) against healthy controls. It aims to better tell these liver conditions apart and understand what is different between them.
Cleveland, OhioAges 18–75 - NCT00345930Recruiting
Study of liver injury after medicines or supplements
This study looks at people (including children over age 2) who develop liver injury that may be caused by a drug or a complementary/alternative medicine (CAM) product. It helps doctors better understand what causes the injury and how to evaluate it.
Los Angeles, CaliforniaAges 2 years+ - NCT07288905Recruiting
Exercise with blood flow restriction for healthy people and CKD patients
This study tests if combining exercise with blood flow restriction training (BFRT) is safe and helpful for healthy adults and people with chronic kidney disease (CKD). It aims to improve strength and health without heavy weights.
TainanAges 20–85 - NCT07582458RecruitingPhase 2/Phase 3
Modafinil for Fatigue in Controlled Inflammatory Bowel Disease
This trial tests whether modafinil (a wakefulness-promoting medication) can reduce severe fatigue in people with inflammatory bowel disease (IBD) whose disease is well-controlled. If you have persistent exhaustion despite your IBD being stable, this study may help determine if this medication works for you.
Arnhem, GelderlandAges 18–75 - NCT04442334Recruiting
European registry for people with fatty liver
This registry collects health and lifestyle information from adults with suspected or confirmed fatty liver (NAFLD) to help researchers better understand the condition. You may be asked about diet, exercise, alcohol intake, and some liver-related tests.
AntwerpAges 18–100 - NCT03929900Recruiting
Study follow-up for kidney disease in adults (non-dialysis)
This study follows adults with chronic kidney disease who are not on dialysis. It aims to better understand kidney health and test what care or monitoring might help over time.
Seoul, Jongno-guAges 45–79 - NCT06095466Recruiting
Heart check with ultrasound in severe liver disease
This study tests if a simple bedside heart ultrasound (echocardiogram) and blood tests can spot early heart problems in people with severe liver disease (cirrhosis) who are in the intensive care unit. It may help doctors better understand and manage heart complications in cirrhosis.
Sector-12, ChandigarhAges 18–65 - NCT07845929Recruiting
AI help for clearer low-dose CT images
This study tests an artificial intelligence model that helps create clearer images from a lower-dose CT scan, which could mean less radiation exposure during your procedure. It aims to improve image quality while keeping radiation doses as low as possible.
Hefei, AnhuiAges 18 years+ - NCT05570929Recruiting
Study of kidney changes before and around donation
This study follows people who are planning kidney donation or a kidney transplant to better understand how kidney function changes over time. It may help researchers predict risk and improve care by studying health markers in detail.
BerlinAges 18–75 - NCT07804316Recruiting
Food choice app for chronic kidney disease patients
This study tests a mobile app that helps people with chronic kidney disease (CKD) make healthier food choices. It aims to empower you to manage your condition better through daily food tracking and personalized guidance.
SingaporeAges 21 years+ - NCT06576479Recruiting
Supplement study for kidney disease and weight loss
This study tests if a special drink can improve nutrition and quality of life in people with chronic kidney disease (CKD) who are not on dialysis. It is for those who have lost weight or have poor appetite.
Guadalajara, JaliscoAges 18–90 - NCT07547878Enrolling by invitationPhase 4
Starting four kidney-protective medicines together for type 2 diabetes
This study looks at whether starting four recommended medications all at once—instead of one by one—is safe and better for protecting the kidneys in people with type 2 diabetes and early kidney damage. You would receive all four medicines together and be closely monitored by the study team.
Temple, TexasAges 18–84 - NCT07496177RecruitingPhase 2
HTD1801 for kidney function in diabetes and kidney disease
This trial tests whether a new drug, HTD1801, can protect or improve kidney function in people with type 2 diabetes and chronic kidney disease. It may help slow kidney damage and reduce protein in urine.
Weifang, ShandongAges 18–75 - NCT05356325Recruiting
Testing FGF23 in anemia with and without kidney disease
This study looks at a blood hormone called FGF23 and whether it is linked to heart (cardiovascular) problems in people with anemia. It also compares people with anemia who do and do not have chronic kidney disease, which may help researchers understand risk and targets.
CórdobaAges 18–85 - NCT05014178Recruiting
Kidney salt imaging scan with MRI
This study uses an MRI scan to look at how your kidneys handle salt (sodium). It may help researchers better understand kidney function in healthy people and in people with chronic kidney disease.
London, OntarioAges 18 years+ - NCT07333313Recruiting
Study of oral medicine and probiotics for kidney disease in diabetes
This trial tests if an oral medication that absorbs toxins plus probiotics can reduce inflammation and slow kidney damage in people with diabetes-related kidney disease (DKD). It may help those with mild to severe kidney function loss.
Taipei, TaiwanAges 20 years+ - NCT07290842Recruiting
Dietary nitrate for high blood pressure kidney injury
This study tests whether a natural substance found in leafy greens (dietary nitrate) can help protect the kidneys of people with high blood pressure and early kidney damage. It may offer a simple dietary way to slow kidney disease.
HerningAges 18–70
Hear when a new Chronic Liver Disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for chronic liver disease?
- Yes. Clin2 currently lists 388 recruiting chronic liver disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic liver disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic liver disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.