Clinical trials
Chronic Medical Conditions clinical trials
Below are recruiting chronic medical conditions clinical trials, each written for real people, not researchers. We’re tracking 208 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05981573Recruiting
Measuring methadone doses for chronic pain
This trial is for people with chronic pain who take daily methadone. It aims to measure how much methadone is in your body to help doctors find the right dose.
Lemon Grove, CaliforniaAges 18–70 - NCT06955143Recruiting
Blood study for acute coronary syndrome patients
This study examines blood samples from people with different types of coronary artery disease to understand the condition better. It may help doctors learn how to treat heart problems in the future.
Lishui, ZhejiangAges 18 years+ - NCT06544525Recruiting
Pain test to predict physical therapy results for back pain
This trial tests whether a simple pain test can predict how much you will improve with physical therapy for chronic low back pain. It looks at how your body naturally handles pain, which may help tailor your treatment.
Fort Sam Houston, TexasAges 18–64 - NCT06556407Recruiting
Kidney nerve treatment for high blood pressure in dialysis patients
This trial tests a procedure called renal denervation (using radio waves to calm overactive nerves in the kidney) to see if it helps lower blood pressure in people on dialysis who have resistant high blood pressure.
Erlangen, BavariaAges 18–99 - NCT06360380Recruiting
Wearable device for fluid removal in heart failure
This trial tests a wearable device that removes extra fluid from your body without using the kidneys. It may help people with heart failure who still have fluid buildup despite taking high doses of water pills.
La Jolla, CaliforniaAges 21–79 - NCT07124598Recruiting
Virtual reality for pain and opioid use
This study tests if virtual reality can help people with chronic pain and opioid use disorder feel better. It looks at how VR might reduce pain and support healthier coping.
The Bronx, New YorkAges 18 years+ - NCT05592717Recruiting
YUTIQ implant for chronic non-infectious eye inflammation
This trial tests whether a small steroid implant placed inside the eye (YUTIQ 0.18 mg) can control chronic non-infectious uveitis. It may help reduce active inflammation and prevent flare-ups, as long as you’ve had recent signs of active disease and can follow the medication and eye-visit rules.
Tianjin, Tianjin MunicipalityAges 18–70 - NCT06567210Recruiting
Insomnia treatment and emotional memory regulation for mental health
This study tests whether treating insomnia can help regulate emotional memories overnight, which may reduce the risk of developing or worsening mental health conditions. You may be eligible if you have both insomnia and some anxiety symptoms.
Macquarie Park, New South WalesAges 18–45 - NCT07536035Recruiting
Comparing Hospital Care Pathways for Acute Medical Illness
This study compares two different hospital care pathways for adults admitted with acute medical emergencies like infections, falls, or COPD flare-ups. The goal is to see which pathway provides more appropriate and effective care.
SingaporeAges 21 years+ - NCT06083597Enrolling by invitation
Developing a pelvic pain questionnaire for women
This study aims to develop a new questionnaire to better understand and measure chronic pelvic pain in women, especially when it's linked to enlarged pelvic veins. You will be asked to take part in interviews and fill out surveys to help create a tool that reflects your experience.
New York, New YorkAges 18–60 - NCT07185061Recruiting
Sound treatment for chronic tinnitus
This study tests whether a special sound-based treatment can help people with chronic tinnitus (ringing in the ears). If your tinnitus has lasted more than six months and you don't have other ear or brain problems, you may be able to join.
Nanjing, JiangsuAges 18 years+ - NCT06849466Enrolling by invitationPhase 4
Perioperative dexmedetomidine for chronic pain after lung surgery
This study tests whether giving the medication dexmedetomidine during and after surgery can prevent long-term pain after a thoracoscopic lung resection. If you are scheduled for this type of lung surgery, you may be able to join and help see if this drug makes recovery less painful over time.
Beijing, Beijing MunicipalityAges 18–80 - NCT05700279Recruiting
PTSD treatment to help prevent future chronic pain
This study tests whether treating post-traumatic stress disorder (PTSD) right when you come to the emergency room for new, acute pain can lower the chance you develop long-term (chronic) pain. It may help people whose pain and trauma symptoms start around the same time.
Chicago, IllinoisAges 18–70 - NCT07419152Recruiting
Yoga for chronic insomnia
This study tests whether yoga can help people with chronic insomnia sleep better. You will practice yoga regularly and see if it improves your sleep quality.
New Delhi, National Capital Territory of DelhiAges 18–65 - NCT05448833Recruiting
Testing a wireless sensor to monitor left heart pressure
This study tests whether a small wireless sensor can safely measure and track pressure in the left upper heart chamber in people with advanced chronic heart failure. It may help the care team better understand pressure changes that are linked to fluid buildup and symptoms, alongside your usual heart medicines.
Petah TikvaAges 22–88 - NCT07158658Recruiting
Study of a new skin graft for pressure sores
This trial tests a new skin graft called NeoThelium FT for stage 2 or 3 pressure ulcers on the pelvis or lower leg. It’s for adults whose wounds are not infected and who can use a wound vacuum to help healing.
Bossier City, LouisianaAges 18 years+ - NCT07662889Enrolling by invitation
Comparing two types of dialysis for kidney failure
This trial compares a newer type of dialysis called hemodiafiltration with standard hemodialysis to see if it improves certain health measures in people with end-stage kidney disease. It may help determine which method works better for long-term treatment.
Lahore, Punjab ProvinceAges 18–70 - NCT06935786Recruiting
Sedentary lifestyle and health risks in kidney disease
This study looks at how a sedentary (mostly sitting or lying down) lifestyle affects people with advanced chronic kidney disease. It aims to see if being less active is linked to higher risks of death or major health problems.
PoriAges 40 years+ - NCT06299683Recruiting
Pain type and bladder pain syndrome treatment study
This study is testing if the type of pain you feel can help predict which treatments work best for interstitial cystitis (a condition that causes bladder pain and pressure). It may help match you with more effective care.
Franklin, TennesseeAges 18 years+ - NCT07020533RecruitingPhase 1
CMV vaccine for stem cell transplant recipients
This trial tests a vaccine designed to boost immunity against CMV (a common virus) and prevent active CMV infection in people receiving a half-matched stem cell transplant. It may help protect you from CMV-related complications after transplant.
Duarte, CaliforniaAges 18–75 - NCT06918561Recruiting
NeoThelium FT for chronic open wounds
This trial tests a new skin-like graft called NeoThelium FT to see if it helps chronic open wounds heal faster. It is for adults with a non-infected wound that has been open for at least 4 weeks and is not a diabetic, pressure, or burn wound.
Denham Springs, LouisianaAges 18 years+ - NCT04759274Recruiting
Personalized water pill dosing support for kidney and fluid overload
This trial tests a decision-support tool to help your care team safely adjust water pills (“diuretics”) when you have kidney disease and fluid buildup. It may help reduce swelling by guiding dosing using your home weight and blood pressure.
Dallas, TexasAges 18 years+ - NCT05537662Recruiting
Testing a wearable system to reduce diabetic nerve back pain
This study tests an Abbott device that uses sensing and electrical stimulation to help reduce chronic back and/or leg pain. It also tracks pain changes and diabetic control using wearables and regular questionnaires to see if the system improves outcomes.
Chicago, IllinoisAges 18 years+ - NCT05866952Recruiting
Breathing and blood-flow testing in long-COVID symptoms
This trial studies how the lungs’ breathing (airflow) and blood flow may be off in people with long-COVID symptoms like tiredness, shortness of breath, or trouble exercising. It may help researchers understand what’s driving symptoms and what kinds of abnormalities could be targeted.
Boston, MassachusettsAges 18–99
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Common questions
- Are there clinical trials for chronic medical conditions?
- Yes. Clin2 currently lists 208 recruiting chronic medical conditions studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic medical conditions trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic medical conditions trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.