Clinical trials
Chronic Medical Conditions clinical trials
Below are recruiting chronic medical conditions clinical trials, each written for real people, not researchers. We’re tracking 206 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06543381RecruitingPhase 1
Olutasidenib for IDH1-mutated blood cancers after transplant
This trial tests a drug called olutasidenib for people with certain blood cancers (AML, MDS, or CMML) that have a specific IDH1 gene change. The goal is to see if it can help prevent relapse after a donor stem cell transplant.
Duarte, CaliforniaAges 18 years+ - NCT04759274Recruiting
Personalized water pill dosing support for kidney and fluid overload
This trial tests a decision-support tool to help your care team safely adjust water pills (“diuretics”) when you have kidney disease and fluid buildup. It may help reduce swelling by guiding dosing using your home weight and blood pressure.
Dallas, TexasAges 18 years+ - NCT06374277Recruiting
Pharmacy Coaching to Help After Hospital Stay
This study tests a program where a pharmacist helps you manage your medications after you leave the hospital. It is for people with long-term health conditions who want to stay on track with their medicines.
Knoxville, TennesseeAges 18 years+ - NCT07529392Recruiting
Ear nerve stimulation plus rehabilitation for chronic back pain
This trial tests a non-surgical treatment that stimulates a nerve in your ear while you do rehabilitation exercises to reduce chronic back pain. It may help if you've had pain for more than 6 months and pain medications aren't working well enough.
Baden, Lower AustriaAges 30–65 - NCT06398873Recruiting
Dupilumab and nasal lining in chronic sinusitis with polyps
This study tests whether dupilumab, a medication given as an injection, helps improve the lining of the nose in people with chronic sinus inflammation and nasal polyps. If you have nasal polyps and are about to start dupilumab, or if you have sinusitis without polyps, you may be eligible to join.
Vienna, AustriaAges 18–99 - NCT07290140Recruiting
Balloon treatment for chronic sinusitis
This trial tests a balloon coated with a medicine (paclitaxel) to treat chronic sinusitis. It may help reduce inflammation and improve sinus drainage in adults with long-lasting sinus problems.
Birmingham, AlabamaAges 18 years+ - NCT07068438Recruiting
Pulsed electric field for chronic bronchitis
This study tests a new treatment that uses brief electric pulses to clear blocked airways in people with chronic bronchitis. It might help if you have a long-term cough with mucus and standard medicines aren't enough.
Hefei, AnuiAges 35–80 - NCT06255678Recruiting
Angio-based check of heart artery treatment effect
This trial tests if special software can check the result of a balloon or stent procedure by looking at the X-ray movie of your heart arteries. It may help doctors decide if more treatment is needed.
WarsawAges 18 years+ - NCT07671378RecruitingPhase 2
Study of zanubrutinib plus sonrotoclax for high-risk CLL/SLL
This trial tests a combination of two targeted drugs (zanubrutinib and sonrotoclax) as a first treatment for people with high-risk chronic lymphocytic leukemia or small lymphocytic lymphoma (CLL/SLL). It aims to see if this approach works better than standard care by using a test called MRD to guide treatment duration.
Nanjing, JiangsuAges 18–75 - NCT03168802Recruiting
Ultrasound and nerve treatment for facet-joint low back pain
This study tests whether a procedure that uses focused ultrasound (MRgFUS) and/or a radiofrequency nerve treatment can reduce long-lasting low back pain caused by facet-joint arthritis. It may help people whose pain improves strongly after a targeted numbing injection to specific back nerves.
Taipei, Please SelectAges 20–79 - NCT07161479Recruiting
Comparing two ways to remove small stomach growths
This study compares two ways to remove tiny, non-cancerous stomach growths—using a gentle heat tool (argon plasma coagulation) or a special scope to cut them out. The goal is to see which method is safer and works better.
Goyang-siAges 20 years+ - NCT06734026Recruiting
Enriched environment rehab for chronic brain injury
This study tests a rich, supportive environment (including exercise, social activities, and cognitive tasks) to help people with chronic brain injury improve their mobility and overall function. If you have a brain injury that happened more than 3 months ago and can stand with support, you may be able to join a program that focuses on your recovery.
Cleveland, OhioAges 18 years+ - NCT03876054Recruiting
Tracking outcomes after Abbott neurostimulator implantation
This study follows people long-term after they get an Abbott device implanted to help with chronic pain. It aims to learn how well the therapy works in real-world care over time.
Phoenix, ArizonaAges 18 years+ - NCT07483372RecruitingPhase 1
SC101 injection for resistant hypertension with kidney disease
This early-phase trial tests an injection called SC101 into the fat around your kidney. It aims to help lower blood pressure in people whose hypertension is poorly controlled despite multiple medications and who have moderate to severe chronic kidney disease.
Suzhou, JiangsuAges 18–65 - NCT07308951Recruiting
Electrical acupoint stimulation for chronic cancer pain relief
This trial tests if a small, patient-controlled device that sends mild electrical pulses to acupoints (like acupuncture without needles) can improve quality of life for people with ongoing cancer pain. It may offer a drug-free way to manage pain at home.
Zhejiang, HangzhouAges 18–80 - NCT06971874Recruiting
Sleep apnea and kidney disease: A study on outcomes
This trial looks at how obstructive sleep apnea affects people with chronic kidney disease (stages 3-4). It aims to help understand the connection between these conditions and guide better care.
Guangzhou, GuangdongAges 18–75 - NCT06453109Recruiting
Focused ultrasound for chronic back pain with opioid use
This study tests whether focused ultrasound (a non-invasive treatment using sound waves) can help people with chronic back pain who also have opioid use disorder and anxiety. It aims to find a better way to manage pain without relying on opioids.
Washington D.C., District of ColumbiaAges 18–75 - NCT06763653Recruiting
Low-frequency device for chronic low back pain
This trial tests a new device that uses very low-frequency electrical pulses to treat chronic low back pain. It is for people whose pain hasn't improved with other treatments and who are not candidates for stronger therapies.
Norwood, South AustraliaAges 22 years+ - NCT07465627Recruiting
Vessel recoil study for below-knee artery disease
This study tests a new device called the Spur to open blocked arteries below the knee in people with severe leg pain or minor wounds. It is specifically for people who also have diabetes or are on dialysis.
GrazAges 18 years+ - NCT06094257Recruiting
Study on sensation and satisfaction after mastectomy
This study looks at how people feel after mastectomy, including transgender patients and those having nipple-sparing surgery. It aims to understand sensation and satisfaction to improve future care.
Boston, MassachusettsAges 18 years+ - NCT05031897RecruitingPhase 2
Haplo transplant with reduced donor mismatch and radiation
This trial tests a special bone marrow/stem cell transplant approach using a partially matched family donor, along with conditioning treatment that involves radiation. It aims to help treat certain blood cancers by replacing damaged blood-forming cells with new ones from the donor.
Philadephia, PennsylvaniaAges 18 years+ - NCT07058376Enrolling by invitation
Herbal medicine for chronic low back pain
This trial tests whether a herbal medicine strategy can safely and effectively reduce chronic low back pain lasting over 3 months. It may be an option if your pain has been moderate to severe and you are looking for alternative treatments.
Seoul, Gangnam-GuAges 19–69 - NCT06442566RecruitingPhase 1/Phase 2
Enhancing opioid therapy for chronic pain with buprenorphine, counseling, and brain stimulation
This study is testing whether adding a medication (buprenorphine), counseling, and a type of brain stimulation (TMS) can improve long-term opioid therapy for chronic pain. If you have been taking prescription opioids daily for at least 3 months and have extra risk factors for opioid-related problems, this trial may offer you new ways to manage pain and reduce risks.
Charleston, South CarolinaAges 18 years+ - NCT07368946Recruiting
Phosphate study for people with kidney disease
This study looks at how the body handles phosphate in people with chronic kidney disease. It may help researchers understand how to better manage phosphate levels to improve health.
Dallas, TexasAges 18 years+
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Common questions
- Are there clinical trials for chronic medical conditions?
- Yes. Clin2 currently lists 206 recruiting chronic medical conditions studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic medical conditions trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic medical conditions trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.