Clinical trials
Chronic Pain Syndrome clinical trials
Below are recruiting chronic pain syndrome clinical trials, each written for real people, not researchers. We’re tracking 227 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06996574Recruiting
Comparing an all-in-one procedure with at-home screening for chronic pain
This trial tests if a single, all-in-one procedure works as well as the usual two-step process (screening at home first) for people with long-term nerve pain. It looks at how well pain is controlled and whether the simpler approach saves money.
AmsterdamAges 18 years+ - NCT07459790RecruitingPhase 2/Phase 3
A new treatment for interstitial cystitis with Hunner's lesions
This study tests a new treatment for women with interstitial cystitis (also called painful bladder syndrome) who have Hunner's lesions (specific sores in the bladder lining). The goal is to see if the new treatment can reduce pelvic pain, frequent urination, and other symptoms.
MoscowAges 18–65 - NCT05100381Recruiting
Dry needling for long-lasting lower back muscle pain
This study tests whether dry needling (thin needles placed into specific muscles) can reduce moderate, long-lasting lower back pain. It focuses on people who have pain from trigger points in a specific back muscle, rather than pain caused by other medical problems.
Tehran, Tehran ProvinceAges 18–45 - NCT07165353Recruiting
Virtual walking to reduce nerve pain after spinal cord injury
This study tests if using a virtual reality walking program can help reduce chronic nerve pain in people with spinal cord injuries. If you have nerve pain in your trunk or legs, you might benefit from this non-drug approach.
Nottwil, Canton of LucerneAges 18–75 - NCT03584815Recruiting
Test of physiotherapy versus surgery for exercise leg muscle pressure
This trial compares a physiotherapy program to a surgical procedure (fasciotomy) for chronic “compartment” pressure in the lower leg triggered by exercise. If you have symptoms that reliably come on with walking/running and improve with rest, the study may offer a structured way to find the best treatment for you.
Copenhagen, CopehagenAges 18–50 - NCT07134699Recruiting
Back pain's effect on thinking in older adults
This study looks at how long-term lower back pain affects thinking skills like memory and attention in adults aged 60 to 85. Participants must speak Cantonese, be right-handed, and have normal thinking abilities. The study uses email or text for some tasks.
Hong KongAges 60–85 - NCT07403331Recruiting
Nerve pain in legs: spinal cord stimulation plus team care
This trial tests a treatment bundle that combines a spinal cord stimulator (a device that sends mild electrical pulses to your spine to block pain signals) with a team of specialists (like a psychologist and physical therapist) to reduce chronic nerve pain in the legs and improve your ability to move and function.
OsloAges 18–60 - NCT06641102Recruiting
Healing track for chronic back pain
This trial tests a non-drug, talk-based therapy approach for chronic back pain. It may help you manage pain without medication, and all study activities can be done from home using your smartphone.
New York, New YorkAges 21–70 - NCT05817786Recruiting
Electrical nerve stimulation for persistent arm nerve pain
This trial tests whether stimulating the nerve roots in the shoulder area can reduce long-lasting nerve pain in one arm. It may help people whose arm pain has not improved with standard nerve-pain treatments.
Lyon, FranceAges 1.5 years–80 years - NCT06087510RecruitingPhase 4
Different doses of esketamine and dexmedetomidine for pain after scoliosis surgery
This trial tests two different doses of esketamine and dexmedetomidine to see which provides better pain relief after scoliosis correction surgery. It aims to improve your recovery and long-term outcomes.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06453109Recruiting
Focused ultrasound for chronic back pain with opioid use
This study tests whether focused ultrasound (a non-invasive treatment using sound waves) can help people with chronic back pain who also have opioid use disorder and anxiety. It aims to find a better way to manage pain without relying on opioids.
Washington D.C., District of ColumbiaAges 18–75 - NCT06578234RecruitingPhase 4
Comparing Adenosine Doses for Heart MRI
This study will compare different doses of adenosine during a heart MRI to find the best dose for measuring blood flow to the heart muscle. It is for people with known or possible coronary artery disease or heart failure, as well as healthy volunteers.
LundAges 40 years+ - NCT06885931Recruiting
Nerve stimulation trial for mixed urinary incontinence
This trial tests a new implant that stimulates a nerve in your pelvic area to help control both stress and urge urine leaks. It might be an option if you've tried other treatments like bladder training or medicine and they didn't help enough or caused side effects.
Leuven, Herestraat 49Ages 22 years+ - NCT06977100Recruiting
Journaling study for jaw pain with other chronic pain conditions
This study tests if a journaling program can help people with jaw pain and at least one other chronic pain condition (like fibromyalgia, IBS, or migraines). You will write about your thoughts and feelings to see if it reduces pain and improves well-being.
Gainesville, FloridaAges 18–80 - NCT07409337Recruiting
Self-acupressure for period pain and PMS
This trial tests if doing acupressure on yourself can reduce period pain and premenstrual symptoms over about six months. It might help if you have painful periods and are looking for a non-medicine option.
Niğde, MerkezAges 18–30 - NCT07624136Recruiting
Kinesio Taping for Shoulder Flexibility and Range of Motion
This study tests whether a special athletic tape (Kinesio tape) applied to your lower back and shoulder area can improve flexibility and reduce shoulder pain in people with chronic shoulder impingement syndrome—a condition where shoulder structures get pinched, causing long-term pain and stiffness.
Ankara, AltindagAges 20–40 - NCT06708000Enrolling by invitationPhase 3
Personalized testing for new chest pain
This trial compares a personalized evaluation approach to standard care for people with new chest pain who might have heart disease. It aims to see if tailoring tests can improve diagnosis and outcomes.
HerningAges 30–75 - NCT07298941RecruitingPhase 2
Sleep treatment to help with chronic low back pain
This study tests if improving sleep can help people with chronic low back pain feel better and cope with pain. It involves a sleep-focused treatment program and looks at how it affects your overall well-being.
Charlottesville, VirginiaAges 18 years+ - NCT05896826Recruiting
Magnetocardiography to better spot heart attack patients
This study tests whether magnetocardiography—a scan that measures heart signals using magnets—can more accurately identify myocardial infarction (heart attack). It may help doctors detect heart attacks faster and more accurately using safer, non-invasive testing.
Jinan, ShandongAges 18–79 - NCT07591584Recruiting
Digestive Enzyme Blend for Bloating and Gas Relief
This study tests whether a daily digestive enzyme supplement designed to break down certain hard-to-digest foods can reduce bloating and belly pain. You'll use a smartphone app to track your symptoms over several weeks to see if the enzyme helps.
Los Angeles, CaliforniaAges 18 years+ - NCT06977321Recruiting
Taping vs mud therapy for carpal tunnel syndrome
This study tests whether taping therapy (kinesiotaping) or a mud pack treatment (peloidotherapy) can help reduce pain and improve function for people with mild to moderate carpal tunnel syndrome. It may be an option if you want non-surgical, drug-free relief.
KonyaAges 1.5 years–5.4 years - NCT04217733RecruitingPhase 3
Ethosuximide plus pentoxifylline for IBS belly pain
This Phase 3 study tests whether two medicines (ethosuximide and pentoxifylline) can reduce belly pain from irritable bowel syndrome (IBS). It may help people whose IBS pain has been moderate to severe recently and who can keep their current IBS treatment steady.
TantaAges 18 years+ - NCT05066334RecruitingPhase 2
Back pain trial using your own stem cells in discs
This Phase 2 trial tests whether injecting your own stem cells into a few back discs can reduce chronic low back pain that has not improved with standard treatments. It may help by targeting disc-related (degenerative) wear seen on MRI, but it requires detailed MRI and blood test screening.
Roma, ItalyAges 18–65 - NCT04085406Recruiting
Deep brain stimulation for hard-to-treat low back pain
This trial studies deep brain stimulation (DBS) to reduce severe low back pain that hasn’t improved after many standard treatments and procedures. It may help people whose pain is long-lasting and not fixable with another surgery.
Los Angeles, CaliforniaAges 40–75
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Common questions
- Are there clinical trials for chronic pain syndrome?
- Yes. Clin2 currently lists 227 recruiting chronic pain syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic pain syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic pain syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.