Chronic Postoperative Pain clinical trials

Liposomal bupivacaine for pain after lung surgery

This trial tests if a long-acting numbing medicine called liposomal bupivacaine can reduce pain after video-assisted lung surgery. It aims to help patients feel better after the procedure with less need for other painkillers.

Numbing medicine for lung surgery pain relief

This trial tests whether a numbing medicine (liposomal bupivacaine) injected near the ribs can reduce pain after lung surgery. If you qualify, you may experience less pain and need fewer painkillers after your operation.

Pain control after scoliosis surgery: comparing two numbing medicines

This study compares two types of numbing medicine used during scoliosis surgery to see which provides better pain relief after the operation. One is a long-acting version (liposomal bupivacaine) and the other is a standard short-acting mix (bupivacaine with epinephrine). If you are a teen having surgery for Adolescent Idiopathic Scoliosis, this trial may help find a way to reduce pain and possibly lessen the need for opioids afterward.

Comparing two numbing medicines for lung surgery pain

This study compares two types of numbing medicine (liposomal vs. hydrochloride bupivacaine) injected near the ribs during lung surgery. The goal is to see which one provides better pain relief after the operation.

Comparing nerve blocks for pain after knee arthroscopy

This study compares two different types of nerve blocks to see which provides better pain relief after arthroscopic knee surgery. You will receive one of the blocks after your surgery, and your pain levels will be tracked.

Pain control after lower back fusion surgery

This trial tests a new pain management plan for people having spinal fusion surgery on their lower back. It aims to find the best way to control pain while reducing side effects.

Comparing IV Methadone vs Spinal Morphine for Pain After Abdominal Surgery

This study compares two strong painkillers—methadone given through an IV versus morphine injected into the spine—to see which provides better pain relief and recovery after major abdominal surgery. It may help you if you're having open surgery and want less pain afterward.

Online therapy for back pain and recovery after spinal fusion

This trial tests if internet-based cognitive behavioral therapy can help people recover better after lumbar fusion surgery by reducing pain, strengthening back muscles, and improving outlook on recovery. You can participate from home using WiFi.

Managing breathing tube pressure to reduce throat problems in older adults

This study tests a way of managing the air pressure in a breathing tube mask used during surgery. The goal is to reduce throat and voice box problems after surgery in older patients.

Pain reduction after lung surgery using different robot methods

This trial compares three ways to do robotic lung surgery to see which one causes less pain afterward. If you are having lung surgery, it may help your recovery be more comfortable.

Pericapsular Nerve Group (PENG) Block on Postoperative Pain Management After Acetabular Fracture Fixation

Ultrasound-Guided Knee Block Study for Knee Replacement

This study looks at whether using ultrasound to guide a numbing injection around the knee can improve pain control after knee replacement surgery. It aims to make recovery more comfortable.

Pain block vs morphine injection for chest surgery

This study compares two ways to manage pain after video-assisted chest surgery (VATS): a numbing injection near the shoulder blade (serratus posterior superior intercostal plane block) versus a small dose of pain medicine in the spine (intrathecal morphine). The goal is to find which approach works better and has fewer side effects.

Nerve blocks vs local numbing for lumbar spine surgery

This study compares two types of nerve blocks (a longissimus plane block and a multifidus plane block) to a local numbing injection for pain control during lumbar spine surgery. It aims to find which method works best for patients having back surgery.

Comparing Two Nerve Blocks for Hip Replacement Pain Relief

This study compares two types of nerve blocks (iliopsoas block and PENG block) to see which one provides better pain relief and recovery after hip replacement surgery. If you are having a hip replacement with spinal anesthesia, you may be a good candidate.

Deep muscle relaxants for less pain after children's belly-button surgery

This study looks at whether giving a deep muscle relaxant during your child's belly-button surgery can reduce pain after the operation. It may help kids feel better and recover more comfortably.

Comparing two pain medicines for gynecologic cancer surgery

This trial compares two different pain medicines (methadone given by mouth or IV vs. hydromorphone given through a spinal injection) after surgery for gynecologic cancer. It aims to find which option provides better pain relief with fewer side effects.

Pain relief after heart surgery: nerve block vs lidocaine drip

This trial compares two ways to manage pain after open-heart surgery: an ultrasound-guided nerve block (PIFB) versus lidocaine given through a vein. The goal is to see which method works better and helps you recover more comfortably.

Liposomal bupivacaine for pain after laparoscopic surgery

This trial tests a long-acting painkiller injected during surgery to see if it reduces pain after keyhole (laparoscopic) procedures like gallbladder removal, hernia repair, or appendix removal. It may help you need fewer opioids and recover more comfortably.

Testing a long-lasting numbing medicine for pain after laparoscopic surgery

This trial is testing if a special numbing medicine called liposomal bupivacaine, given as a nerve block during surgery, can help reduce pain after laparoscopic procedures like gallbladder removal or hernia repair. It might help you feel better with less need for strong painkillers.

Pain relief patch after laparoscopic abdominal surgery

This trial tests whether a pain-relief patch (loxoprofen) works well and safely to reduce pain after common laparoscopic surgeries like gallbladder, appendix, or hernia repair. If it works, it could offer patients a non-invasive way to manage post-surgery pain.

Liposomal bupivacaine for pain after gynecologic cancer surgery

This trial tests whether a long-acting numbing medication (liposomal bupivacaine) injected into the abdominal wall can reduce pain after laparoscopic surgery for gynecologic cancer. If effective, it may help patients recover with less discomfort and fewer painkillers.

Smallest effective dose of bupivacaine for chest surgery pain block

This trial tests the smallest amount of bupivacaine (a numbing medicine) needed to control pain after keyhole chest surgery. You will receive a nerve block before surgery, and the goal is to find the best dose with fewer side effects.

Nerve Block With or Without Extra Medicine for Hip Replacement

This trial compares two types of nerve blocks for pain relief after total hip replacement. One block uses a standard numbing medicine, and the other adds a medication (dexmedetomidine) that may extend the pain relief. The goal is to see which approach works better for managing pain after surgery.