Clinical trials
Chronic Postoperative Pain clinical trials
Below are recruiting chronic postoperative pain clinical trials, each written for real people, not researchers. We’re tracking 298 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03858231RecruitingPhase 4
Opioid vs non-opioid pain relief after knee arthroscopy
This study compares opioid pain medicine with non-opioid pain medicine after arthroscopic (keyhole) knee surgery. It aims to see which approach controls pain well while keeping side effects and risks lower.
Fargo, North DakotaAges 18–80 - NCT07360392Recruiting
Nerve block comparison for knee replacement pain
This study compares two numbing techniques (nerve blocks) for pain relief after knee replacement surgery. The goal is to find which one works better and helps you recover with less pain.
AmasyaAges 18–80 - NCT07467577Recruiting
Does washing the belly during hysterectomy reduce pain?
This trial tests whether rinsing the belly with clean fluid during a hysterectomy (done through the vagina with small cameras) can lower pain after surgery. It may help if you are having your uterus removed for a non-cancer reason.
MuğlaAges 18–80 - NCT07587320Recruiting
Nerve Blocks for Pain Relief After Heart Bypass Surgery
This trial tests a new pain-management technique using nerve blocks (numbing medicine injected near nerves) to help reduce pain and opioid use after coronary artery bypass grafting (CABG), a common heart surgery. The goal is to help you recover more comfortably with fewer strong pain medications.
Diyarbakır, DiyarbakırAges 18–80 - NCT07541040Recruiting
Nerve Blocks for Breast Surgery Pain Relief
This trial tests two different nerve-block techniques to reduce pain after breast surgery. The study compares a serratus block with an ESP block—both are injections of numbing medication near nerves—to see which works better for managing pain without heavy opioid use.
İzmit, KocaeliAges 18–65 - NCT07269106RecruitingPhase 4
Testing anrikefon for pain relief after eye surgery
This trial tests a new painkiller called anrikefon for people having eye surgery under general anesthesia. It aims to see if it's safe and effective for controlling pain after the procedure.
Guangzhou, GuangdongAges 18–70 - NCT06584201Recruiting
Pain block effects on lung function after surgery
This study compares two types of nerve blocks given before surgery to see how they affect your breathing and lung function right after the operation. It is for adults having certain procedures who are generally healthy or have mild to moderate health conditions.
IstanbulAges 18–65 - NCT07689461Recruiting
Virtual reality for pain after hip replacement
This trial tests if using virtual reality can help reduce pain after hip replacement surgery. It may be a good option if you are having a hip replacement and have moderate to severe pain.
MalatyaAges 18–99 - NCT06962306RecruitingPhase 4
Pain relief study for children having cleft palate surgery
This trial tests different ways to manage pain after cleft palate repair in young children. The goal is to find which approach works best to lower pain and improve recovery.
Durham, North CarolinaAges 6 months–4 years - NCT07244029Recruiting
Herbal extract for pain and swelling after wisdom tooth surgery
This trial tests if an herbal extract called Reparil (aescin) can reduce pain, swelling, and stiffness after impacted wisdom tooth removal. It compares Reparil to a standard pain reliever (ibuprofen) to see which works better for recovery.
Muscat, Al KhoudAges 18–40 - NCT07335250Recruiting
Nerve block for pain after lung surgery
This study tests a nerve block (an injection near the spine) to see if it reduces pain after lung surgery (thoracotomy with lobectomy). If you are having planned lung surgery, this could help manage your pain with fewer side effects.
KonyaAges 18–85 - NCT07547774Recruiting
Sleep Quality Before Breast Surgery and Recovery Outcomes
This study examines how well you sleep before breast cancer surgery and whether it affects your recovery afterward. Researchers will ask about your sleep habits and track your healing to understand the connection.
Ankara, YenimahalleAges 18–70 - NCT07527065Enrolling by invitation
Pain Relief Methods for Hernia Surgery Recovery
This study compares two different nerve-blocking injection techniques to help manage pain after open inguinal hernia repair surgery. The goal is to determine which method works better to keep you comfortable during recovery.
ÇorumAges 18–65 - NCT07370129Enrolling by invitation
Numbing injection for pain after tonsil surgery
This study tests a numbing injection near a nerve in your nose to see if it can reduce pain and help you recover faster after tonsillectomy. It is a non-drug approach that may offer an alternative to strong pain medicines.
Ankara, AnkaraAges 12 years+ - NCT04109638Recruiting
PEMF therapy to reduce pain after shoulder or knee surgery
This trial studies whether PEMF, a type of non-surgical device that uses pulsed electromagnetic fields, can reduce pain after shoulder or knee surgery. If you join, you’ll also be expected to do post-surgery physical therapy exercises and report your pain and function.
Redwood City, CaliforniaAges 18 years+ - NCT07504705Recruiting
Comparing two nerve blocks for pain after gallbladder surgery
This trial compares two types of nerve blocks (intertransverse process block and erector spinae plane block) to see which provides better pain relief after gallbladder removal surgery using small incisions (laparoscopic cholecystectomy).
Konya, KonyaAges 18 years+ - NCT07164677Recruiting
Nerve block for pain after open-heart surgery
This study tests a nerve block (an injection near the back muscles) to see if it helps control pain after open-heart surgery. It might be a good option if you are having planned heart surgery through a cut in the middle of your chest.
SamsunAges 18–80 - NCT07442539Recruiting
Numbing medicine for pain after hemorrhoid surgery
This trial tests a long-acting numbing medicine called liposomal bupivacaine to see if it reduces pain after hemorrhoid surgery better than standard care. It may be an option for people who are otherwise healthy and scheduled for this surgery.
Beijing, Beijing MunicipalityAges 18–64 - NCT06381063RecruitingPhase 3
Anti-inflammatory for heart surgery
This trial is testing whether a non-steroidal anti-inflammatory drug (NSAID) given during heart surgery can reduce complications. It's for people having planned open-heart surgery with a heart-lung machine.
AmiensAges 18 years+ - NCT07740915Enrolling by invitation
Pain relief after heart surgery in children
This study compares two types of pain blocks for children having heart surgery for the first time. The goal is to see which block provides better pain relief after surgery, which could help your child recover more comfortably.
Diyarbakır, DiyarbakırAges birth–18 years - NCT07723352Enrolling by invitation
Testing Journavx for Thumb Arthritis Surgery Pain
This trial tests a new pain medicine called Journavx (suzetrigine) for people having thumb arthritis surgery. It aims to see how well the medicine controls pain after the operation.
Philadelphia, PennsylvaniaAges 40–80 - NCT07223580RecruitingPhase 4
Steroid use for pain after kidney stone surgery
This trial tests if giving a corticosteroid during ureteroscopy (a scope procedure to remove kidney or ureter stones) can reduce pain afterward. If you are having this surgery and are not already on steroids or strong pain medicines, this study may help manage your recovery.
Scottsdale, ArizonaAges 18 years+ - NCT06838039Recruiting
A second nerve block for less pain after lung surgery
This study tests whether adding a second nerve block (serratus anterior block) within 24 hours after a lung surgery (VATS) can reduce pain better than the standard nerve block alone. It aims to help patients control pain with fewer strong painkillers.
HebronAges 18–70 - NCT07353996RecruitingPhase 4
Finding the right dose of a new IV painkiller after bone surgery
This trial tests a single dose of a new pain medicine called tegileridine fumarate given through a vein right after orthopedic surgery (like spine, hip, or knee surgery). The goal is to find the best dose that works well for pain without causing side effects.
Hanzhong, ZhejiangAges 18–75
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Common questions
- Are there clinical trials for chronic postoperative pain?
- Yes. Clin2 currently lists 298 recruiting chronic postoperative pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic postoperative pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic postoperative pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Postoperative Pain
- Postoperative Pain, Acute
- Postoperative Pain Management
- Total Knee Arthroplasty (Postoperative Pain)
- POSTOPERATIVE DELIRIUM AND POSTOPERATIVE COGNITIVE DECLINE
- Postoperative Pain After Endodontic Treatment
- Postoperative Pain Following Knee Arthroplasty
- Postoperative Pain Management in Oral Surgery
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.