Clinical trials
Chronic Postoperative Pain clinical trials
Below are recruiting chronic postoperative pain clinical trials, each written for real people, not researchers. We’re tracking 296 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07833930Recruiting
Breakthrough pain after arm numbing block in diabetic patients
This study looks at whether people with diabetes have more breakthrough pain (pain that breaks through despite the block) within 48 hours after an arm surgery with a specific type of nerve block. The goal is to understand and improve pain management for diabetic patients.
TaiyuanAges 18–80 - NCT07689461Recruiting
Virtual reality for pain after hip replacement
This trial tests if using virtual reality can help reduce pain after hip replacement surgery. It may be a good option if you are having a hip replacement and have moderate to severe pain.
MalatyaAges 18–99 - NCT07547774Recruiting
Sleep Quality Before Breast Surgery and Recovery Outcomes
This study examines how well you sleep before breast cancer surgery and whether it affects your recovery afterward. Researchers will ask about your sleep habits and track your healing to understand the connection.
Ankara, YenimahalleAges 18–70 - NCT07541040Recruiting
Nerve Blocks for Breast Surgery Pain Relief
This trial tests two different nerve-block techniques to reduce pain after breast surgery. The study compares a serratus block with an ESP block—both are injections of numbing medication near nerves—to see which works better for managing pain without heavy opioid use.
İzmit, KocaeliAges 18–65 - NCT07527065Enrolling by invitation
Pain Relief Methods for Hernia Surgery Recovery
This study compares two different nerve-blocking injection techniques to help manage pain after open inguinal hernia repair surgery. The goal is to determine which method works better to keep you comfortable during recovery.
ÇorumAges 18–65 - NCT07269106RecruitingPhase 4
Testing anrikefon for pain relief after eye surgery
This trial tests a new painkiller called anrikefon for people having eye surgery under general anesthesia. It aims to see if it's safe and effective for controlling pain after the procedure.
Guangzhou, GuangdongAges 18–70 - NCT07244029Recruiting
Herbal extract for pain and swelling after wisdom tooth surgery
This trial tests if an herbal extract called Reparil (aescin) can reduce pain, swelling, and stiffness after impacted wisdom tooth removal. It compares Reparil to a standard pain reliever (ibuprofen) to see which works better for recovery.
Muscat, Al KhoudAges 18–40 - NCT07229495RecruitingPhase 4
Tegileridine for pain after scoliosis surgery in teens
This trial tests a new pain medicine, tegileridine, for teenagers having spine surgery for scoliosis. It aims to see if it controls pain well after the operation, and if it's safe.
Zhengzhou, HenanAges 10–17 - NCT06962306RecruitingPhase 4
Pain relief study for children having cleft palate surgery
This trial tests different ways to manage pain after cleft palate repair in young children. The goal is to find which approach works best to lower pain and improve recovery.
Durham, North CarolinaAges 6 months–4 years - NCT07805928Recruiting
A guided pain plan after rib remodeling surgery
This study tests a step-by-step pain management plan guided by your pain scores after rib remodeling surgery. The plan uses a mix of medications to reduce pain safely and may help you recover with less discomfort.
BogotáAges 18–55 - NCT07504705Recruiting
Comparing two nerve blocks for pain after gallbladder surgery
This trial compares two types of nerve blocks (intertransverse process block and erector spinae plane block) to see which provides better pain relief after gallbladder removal surgery using small incisions (laparoscopic cholecystectomy).
Konya, KonyaAges 18 years+ - NCT07442539Recruiting
Numbing medicine for pain after hemorrhoid surgery
This trial tests a long-acting numbing medicine called liposomal bupivacaine to see if it reduces pain after hemorrhoid surgery better than standard care. It may be an option for people who are otherwise healthy and scheduled for this surgery.
Beijing, Beijing MunicipalityAges 18–64 - NCT07164677Recruiting
Nerve block for pain after open-heart surgery
This study tests a nerve block (an injection near the back muscles) to see if it helps control pain after open-heart surgery. It might be a good option if you are having planned heart surgery through a cut in the middle of your chest.
SamsunAges 18–80 - NCT04676802RecruitingPhase 2
Pain relief after thumb joint surgery: ibuprofen and acetaminophen versus oxycodone
This study compares two ways to manage pain after thumb joint removal surgery: one using over-the-counter pain relievers (ibuprofen and acetaminophen) and the other using a prescription opioid (oxycodone). The goal is to see if the non-opioid option works just as well with fewer side effects.
Redwood City, CaliforniaAges 45 years+ - NCT04109638Recruiting
PEMF therapy to reduce pain after shoulder or knee surgery
This trial studies whether PEMF, a type of non-surgical device that uses pulsed electromagnetic fields, can reduce pain after shoulder or knee surgery. If you join, you’ll also be expected to do post-surgery physical therapy exercises and report your pain and function.
Redwood City, CaliforniaAges 18 years+ - NCT06381063RecruitingPhase 3
Anti-inflammatory for heart surgery
This trial is testing whether a non-steroidal anti-inflammatory drug (NSAID) given during heart surgery can reduce complications. It's for people having planned open-heart surgery with a heart-lung machine.
AmiensAges 18 years+ - NCT07810816Recruiting
Genetic testing for personalized pain relief after surgery
This study looks at how your genes affect your body's response to tramadol, a painkiller given through a pump after surgery. The goal is to see if your genetic makeup influences pain relief and side effects, which could help personalize pain treatment in the future.
Medellín, AntioquiaAges 18 years+ - NCT07723352Enrolling by invitation
Testing Journavx for Thumb Arthritis Surgery Pain
This trial tests a new pain medicine called Journavx (suzetrigine) for people having thumb arthritis surgery. It aims to see how well the medicine controls pain after the operation.
Philadelphia, PennsylvaniaAges 40–80 - NCT07223580RecruitingPhase 4
Steroid use for pain after kidney stone surgery
This trial tests if giving a corticosteroid during ureteroscopy (a scope procedure to remove kidney or ureter stones) can reduce pain afterward. If you are having this surgery and are not already on steroids or strong pain medicines, this study may help manage your recovery.
Scottsdale, ArizonaAges 18 years+ - NCT07853664RecruitingPhase 2/Phase 3
Dexamethasone and diclofenac gel for facial surgery pain
This study tests a gel containing two pain and swelling medicines applied to the skin after facial surgery or facial injury repair. The goal is to see if it provides better pain relief and less swelling than usual care.
DhamarAges Any age - NCT07830446Recruiting
Pain relief injections for breast surgery
This trial tests whether a special numbing injection (called a fascial plane block) given before breast surgery can reduce pain after the operation. It compares this to standard pain management to see if it helps you recover with less discomfort.
BursaAges 18–80 - NCT07831096Recruiting
Nerve block comparison for shoulder surgery pain relief
This study compares two types of nerve blocks to see which one provides better pain relief after outpatient shoulder surgery. Participants will receive one of the two blocks, and the study will track their pain and recovery.
Varese, ItalyAges 18 years+ - NCT06838039Recruiting
A second nerve block for less pain after lung surgery
This study tests whether adding a second nerve block (serratus anterior block) within 24 hours after a lung surgery (VATS) can reduce pain better than the standard nerve block alone. It aims to help patients control pain with fewer strong painkillers.
HebronAges 18–70 - NCT07441902Recruiting
Numbing medicine for lung surgery pain relief
This trial tests whether a numbing medicine (liposomal bupivacaine) injected near the ribs can reduce pain after lung surgery. If you qualify, you may experience less pain and need fewer painkillers after your operation.
Beijing, Beijing MunicipalityAges 18–64
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Common questions
- Are there clinical trials for chronic postoperative pain?
- Yes. Clin2 currently lists 296 recruiting chronic postoperative pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic postoperative pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic postoperative pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Postoperative Pain
- Postoperative Pain, Acute
- Postoperative Pain Management
- Total Knee Arthroplasty (Postoperative Pain)
- POSTOPERATIVE DELIRIUM AND POSTOPERATIVE COGNITIVE DECLINE
- Postoperative Pain After Endodontic Treatment
- Postoperative Pain Following Knee Arthroplasty
- Postoperative Pain Management in Oral Surgery
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.