Clinical trials
Chronic Respiratory Failure clinical trials
Below are recruiting chronic respiratory failure clinical trials, each written for real people, not researchers. We’re tracking 94 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06881927RecruitingPhase 4
Reducing anti-rejection meds in ICU for kidney transplant patients
This study tests whether quickly reducing your anti-rejection medicines during a life-threatening ICU stay can help your kidneys recover and improve your overall outcome. It is for kidney transplant recipients with septic shock or severe breathing failure.
StrasbourgAges 18 years+ - NCT06227468Recruiting
Mapping immune system genes in Greek adults
This study maps immune system genes (HLA) in Greek adults. It uses a simple cheek swab sample to collect data, with no experimental treatment.
Chaïdári, AtticaAges 18 years+ - NCT06795971Recruiting
Comparing oxygen methods for hypoxemic respiratory failure
This trial compares three ways of giving extra oxygen to people with low blood oxygen levels: a face mask with continuous pressure, a noninvasive ventilator, or high-flow oxygen through the nose. The goal is to see which method helps people avoid needing a breathing tube.
Nanjing, JiangsuAges 18 years+ - NCT06916585RecruitingPhase 2
Testing AS1501 for acute-on-chronic liver failure
This trial tests a new drug called AS1501 for people with acute-on-chronic liver failure (a sudden worsening of chronic liver disease). It aims to see if the drug can help improve liver function and reduce the need for a liver transplant. You may be eligible if you are in the early or middle stage of this condition and have a specific blood marker (high TRAIL level).
Shenzhen, GuangdongAges 18–75 - NCT05026749RecruitingPhase 3
Azithromycin for severe RSV breathing failure in young children
This trial tests whether azithromycin (an antibiotic) can improve outcomes for babies and young children in the ICU who have RSV causing serious breathing problems. It mainly looks at children who start strong breathing support soon after RSV symptoms begin.
Birmingham, AlabamaAges 3 days–2 years - NCT06213168Recruiting
CPAP plus high-flow oxygen vs oxygen alone for breathing failure
This study tests whether adding a breathing machine (CPAP) to high-flow oxygen can help people with sudden breathing failure more than high-flow oxygen alone. It is for adults recently admitted to the ICU with low oxygen levels.
AmiensAges 18 years+ - NCT06510972Recruiting
Eating versus fasting for ICU patients with breathing failure
This study looks at whether it's safe and helpful to let people with severe breathing problems in the ICU eat and drink normally instead of fasting. If you qualify, you may be assigned to either continue eating or to fast while doctors monitor your recovery.
BloisAges 18 years+ - NCT03033251Recruiting
Compare high-flow oxygen to noninvasive ventilation for COPD flare-ups
This study compares two breathing support options for people hospitalized with a COPD flare-up and high carbon dioxide levels in the blood. It aims to see which option works better and is safer for breathing and recovery.
Toronto, OntarioAges 40 years+ - NCT07743021Recruiting
Blood sample study for better health screening
This study collects blood samples and health information over time to improve early detection of diseases. It may help researchers find ways to prevent serious conditions.
BalatonfüredAges 40 years+ - NCT06936618Recruiting
Electrical impedance guided ventilator settings for breathing failure
This trial tests whether using electrical impedance tomography (EIT), a safe and non-invasive monitoring technique, helps doctors set the ventilator better for patients with low oxygen levels. It may improve your breathing support during mechanical ventilation.
BangkokAges 18 years+ - NCT07426380RecruitingPhase 1
Study of eloralintide in people with and without kidney problems
This trial tests how the body handles eloralintide in people with different levels of kidney function, including those on dialysis. It may help determine if the drug is safe and effective for patients with kidney issues.
Miami Lakes, FloridaAges 18–85 - NCT06066502RecruitingPhase 3
Precision ventilation for ARDS
This study tests whether a customized breathing machine approach ("precision ventilation") is better than usual care for patients with ARDS. The goal is to improve oxygen levels and recovery while avoiding lung damage.
Tucson, ArizonaAges 18 years+ - NCT06774534Recruiting
SerpinB3 protein in acute respiratory distress
This study looks at a protein called SerpinB3 and its role in severe lung inflammation (ARDS). It may help doctors understand how ARDS develops and find new ways to treat it.
Padova, PDAges 18 years+ - NCT06114667Recruiting
Nasal high flow vs. mask for COPD flare-up
This study compares two types of breathing support for people having a severe COPD flare-up with high carbon dioxide and acidic blood. It tests if a gentle air flow through the nose (nasal high flow) works as well as a mask (non-invasive ventilation) to help you breathe better.
Montpellier, MontepllierAges 18–85 - NCT07414108Recruiting
Predicting response to breathing support in COPD
This study looks at whether nighttime breathing problems can predict long-term success with a non-invasive breathing machine in people with COPD who have high carbon dioxide levels in their blood. The goal is to help doctors decide who will benefit most from this therapy.
BolognaAges 18 years+ - NCT03667027Recruiting
Study of breathing muscle and lung changes during transplant planning
This trial studies how the diaphragm (your main breathing muscle) and lung/airway tissue behave in people who are being supported until they can get a lung transplant. The results may help doctors better understand breathing failure and improve transplant care.
TorontoAges 18 years+ - NCT06669312Recruiting
Study on a model for ICU patients on high-flow oxygen
This study is testing an existing model (BREF) to see how well it helps doctors make decisions for patients on high-flow oxygen in the intensive care unit. It may help improve care for people needing extra breathing support.
Rozzano, MilanAges 18 years+ - NCT06953180Recruiting
Epigenetics, aging, and disease prevention study in Kazakhstan
This study looks at how your genes and environment affect your risk for non-communicable diseases like heart disease or diabetes. It aims to predict your biological age and help create personalized prevention plans.
Almaty, KazakhstanAges 18–69 - NCT05146336Recruiting
CytoSorb registry for critically ill patients needing blood treatment
This registry collects information about critically ill patients who receive the CytoSorb 300 mL blood treatment. It may help doctors better understand when the treatment works best and when it should not be used.
KlagenfurtAges Any age - NCT05462600Enrolling by invitation
Breathing monitoring test in non-smokers
This study measures how you breathe and how well oxygen and carbon dioxide move in and out of your lungs. It’s mainly a monitoring study to help researchers understand breathing patterns during a breathing test.
La Jolla, CaliforniaAges 18 years+ - NCT05689645RecruitingPhase 2
Drug trial for liver injury or liver failure
This Phase 2 trial tests an injection medicine (F573) to see if it can improve people with liver injury, drug-related liver damage, or liver failure. You may be screened with blood tests, liver stiffness measurements, and possibly symptom checks.
Beijing, Beijing MunicipalityAges 18–60 - NCT05960890Recruiting
Study of chronic heart failure after hospital discharge
This study follows adults with chronic or newly diagnosed heart failure to learn how patients do after they leave the hospital, mainly while taking heart medicines by mouth. It may help researchers better understand which patients have different outcomes and needs.
Taizhou, JiangsuAges 18 years+ - NCT07687186RecruitingPhase 3
Qishen Yiqi pills for chronic heart failure
This trial tests whether Qishen Yiqi Dripping Pills, a Chinese herbal medicine, can help people with chronic heart failure caused by coronary heart disease. It is for adults who have been on stable heart failure treatment for at least two weeks.
Bozhou, AnhuiAges 18–80 - NCT04986332Recruiting
Program for COPD or heart failure in people with other illnesses
This trial studies a detailed, whole-body program to improve outcomes in people with COPD or heart failure, especially those who also have several other chronic conditions. It may help by improving activity and monitoring health markers over about 24 weeks.
PalermoAges 45–75
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Common questions
- Are there clinical trials for chronic respiratory failure?
- Yes. Clin2 currently lists 94 recruiting chronic respiratory failure studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic respiratory failure trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic respiratory failure trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.