Clinical trials
Chronic Spinal Cord Injury clinical trials
Below are recruiting chronic spinal cord injury clinical trials, each written for real people, not researchers. We’re tracking 137 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05267951Recruiting
Closed-loop spinal stimulation to improve hand use after spinal injury
This trial tests a smart form of spinal stimulation that responds to your body’s signals to help improve upper-extremity (arm/hand) function after a spinal cord injury. If it works, it may make everyday hand tasks like dressing, grooming, or feeding easier.
Seattle, WashingtonAges 21–70 - NCT05351827Recruiting
Mild intermittent hypoxia for autonomic function in spinal cord injury
This study is testing whether mild intermittent hypoxia (brief episodes of reduced oxygen) can improve autonomic nervous system function (which controls things like blood pressure and heart rate) in people with incomplete spinal cord injuries. It may help reduce symptoms like dizziness or irregular heart rate.
Detroit, MichiganAges 18–60 - NCT04887688Recruiting
Electrical bandage for chronic wound treatment
This trial tests a new bandage that uses a mild electrical current to help heal chronic wounds. It's for veterans with spinal cord injuries or diabetes who have wounds that haven't healed.
Cleveland, OhioAges 18 years+ - NCT05191121Enrolling by invitation
Rehab program to improve arm and trunk control after spinal injury
This trial helps people with recent traumatic spinal cord injury improve arm movement and trunk (upper body) stability using a training program that includes electrical stimulation. If you’re early after injury and can safely use stimulation, you may benefit from more controlled movement for daily tasks.
Englewood, ColoradoAges 18 years+ - NCT06489106Enrolling by invitation
Spinal stimulation to improve hand function in kids with spinal cord injury
This study tests a noninvasive spinal stimulation device to help children with spinal cord injury regain hand strength and control. It may improve grip and daily activities.
Louisville, KentuckyAges 7–12 - NCT06310226Recruiting
Studying spinal cord stimulation for chronic low back pain
This study is looking at how people with chronic low back pain respond to spinal cord stimulation (a device that sends gentle electrical pulses to the spine to reduce pain). If you already have a spinal cord stimulator, you may help researchers understand how well it works and how it affects your brain.
Los Angeles, CaliforniaAges 18–80 - NCT04054414RecruitingPhase 2
Drug study for improving recovery after acute spinal cord injury
This Phase 2 trial tests sotateltide (PMZ-1620) in people with a recent spinal cord injury. It aims to see whether the drug can improve neurological recovery after injury, especially in certain levels and types of incomplete injuries.
BelagaviAges 18–75 - NCT07739992Recruiting
Acute intermittent hypoxia for spinal cord injury
This study tests a breathing therapy called acute intermittent hypoxia, which involves short bursts of low oxygen, to see if it can improve leg movement in people with spinal cord injury. It may help strengthen the muscles that lift the foot.
Chicago, IllinoisAges 18–75 - NCT07732972Recruiting
Brain and nerve effects of spinal cord stimulation study
This study uses special recordings to understand how a temporary spinal cord stimulator (a device that sends mild electrical pulses) changes brain and nerve activity in people with chronic pain or spinal cord injury. It aims to find out how the stimulation helps the nervous system work better.
Hualien CityAges 20–70 - NCT07722130Recruiting
Spinal cord stimulation to help breathing after neck injury
This trial tests if a device placed near the spinal cord can help people with a neck injury breathe better without a ventilator. It's for those who still need breathing support at least 2 weeks after their injury.
Nanjing, JiangsuAges 18–75 - NCT06924177Recruiting
Spinal cord injury diet study for wheelchair users
This study tests a special diet program for people with spinal cord injuries who use a wheelchair. It aims to see if the diet can improve health and well-being.
Dallas, TexasAges 18–65 - NCT03509558Recruiting
Tapping a device on the back plus leg exercise for walking
This study tests whether a device placed on the back can help improve leg movement and walking ability after a spinal cord injury. It combines the device with supervised physical therapy over many weeks to see if it helps with daily mobility.
Seattle, WashingtonAges 21–70 - NCT03680872Recruiting
Brain-to-nerve study to improve hand movement after spinal injury
This trial tests a “neural bypass” approach to help restore hand movement and feeling in people with tetraplegia from a spinal cord injury. You would have repeated visits for brain/nerve testing and may receive study procedures to see if function improves.
Manhasset, New YorkAges 22–65 - NCT04032990Recruiting
Testing a skin-based nerve stimulation for kids’ arm function
This trial studies whether a painless, skin-based treatment (stimulation over the spine) is safe and feasible to improve arm and hand function in children with a spinal cord injury. It’s mainly designed to see if the approach can be done safely and whether it may help upper-limb skills.
Louisville, KentuckyAges 4–18 - NCT04144972Recruiting
Closed-loop deep brain stimulation for long-lasting nerve pain
This trial tests a “smart” deep brain stimulation device that senses your brain signals and adjusts treatment to reduce severe, long-lasting pain. It may help people whose pain has not improved with multiple pain medicines and surgery cannot fix the cause.
San Francisco, CaliforniaAges 22–80 - NCT04460872RecruitingPhase 2
Testosterone plus walking training to support bones and muscles
This Phase 2 study tests whether testosterone therapy combined with walking training can improve bone and muscle health after a spinal cord injury. It aims to help men with low testosterone and walking problems by improving strength, body composition, and related health markers.
Gainesville, FloridaAges 18 years+ - NCT04883463Recruiting
Brain and spinal stimulation to improve breathing after SCI
This trial tests a neuromodulation treatment to improve breathing in people living with a cervical spinal cord injury who have significant breathing problems. If you qualify, you would have regular weekly testing over many months to see whether breathing and breathing support needs improve.
Los Angeles, CaliforniaAges 18–75 - NCT04921592Recruiting
Arm therapy for people with chronic cervical spinal cord injury
This trial looks at an upper-arm exercise program for people with long-term (at least 6 months) spinal cord injuries in the neck area. It may help improve how you use your arms and manage stiffness, while also checking if the program is safe for participants.
West Orange, New JerseyAges 18 years+ - NCT05157282Recruiting
Spinal cord stimulation to improve hand function after tetraplegia
This trial tests whether a special device that stimulates the spinal cord can help people with long-lasting neck spinal cord injuries recover useful hand movement and grip strength. It may help your nervous system communicate better so daily hand tasks become easier.
Chicago, IllinoisAges 18–70 - NCT05187650Recruiting
Powered exoskeleton plus electrical stimulation for incomplete spinal cord injury
This trial tests whether a powered walking exoskeleton together with electrical muscle stimulation (FES) can improve walking and movement in people with long-term, incomplete spinal cord injury. It may help you stand and walk more safely and effectively than standard care alone.
Nottwil, Canton of LucerneAges 18 years+ - NCT05369520Recruiting
Noninvasive spinal stimulation to improve bladder and autonomic function
This trial tests a noninvasive way to stimulate the spinal cord to help the body’s “automatic functions” (like bladder, bowel, and sexual function) after spinal cord injury. If you’ve had a stable, complete spinal cord injury for more than a year, you may be eligible to try this approach and help researchers evaluate recovery.
Vancouver, British ColumbiaAges 19–60 - NCT05467215RecruitingEarly Phase 1
Brief oxygen breathing trial after spinal cord injury
This early-phase study tests whether a short period of breathing extra oxygen (hyperoxia) soon after lying in one position can improve physical function in people with long-term spinal cord injury. If you qualify, the goal is to see whether this treatment can help your body work better after chronic injury.
Edmonton, AlbertaAges 18–65 - NCT05472584Recruiting
Spinal stimulation with training for leg movement after injury
This study tests whether spinal cord stimulation combined with training can improve your ability to move your legs and do daily tasks. You may be able to join if you have a traumatic incomplete spinal cord injury (or, in some cases, if you’re a healthy volunteer).
St Louis, MissouriAges 16–65 - NCT05644171Recruiting
Epidural spinal stimulation for chronic spinal cord injury recovery
This trial tests whether a stimulating device placed near the spinal cord can help improve movement and rehabilitative function in people with long-term spinal cord injuries. It may help some patients strengthen function, but only if they meet specific injury and health requirements.
SingaporeAges 21 years+
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Common questions
- Are there clinical trials for chronic spinal cord injury?
- Yes. Clin2 currently lists 137 recruiting chronic spinal cord injury studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic spinal cord injury trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic spinal cord injury trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.