Clinical trials
Cognition clinical trials
Below are recruiting cognition clinical trials, each written for real people, not researchers. We’re tracking 2,028 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06584422Recruiting
Online program for depression in older adults
This study tests an online program called Empower@Home that helps older adults with symptoms of depression. It compares the program to usual care to see if it improves mood and well-being.
Ann Arbor, MichiganAges 50 years+ - NCT05994612Recruiting
Suicide prevention for homeless youth using substances
This trial tests a program to help reduce suicide risk in young people who are homeless and use alcohol or drugs. It may provide support and strategies to keep them safe.
Columbus, OhioAges 15–24 - NCT06529055Enrolling by invitation
Caffeine and nicotine pouch effects on exercise and brain function
This trial tests how caffeine and nicotine pouches affect your body during exercise, including heart function, thinking, and behavior. It looks at short bursts of high-intensity activity in healthy men who already exercise regularly.
Hattiesburg, MississippiAges 21–40 - NCT06002477RecruitingEarly Phase 1
Attention study in sickle cell disease
This trial tests a medication to see if it can improve attention in people with sickle cell disease. It may help with thinking and focus.
Nashville, TennesseeAges 55 years+ - NCT06018519Recruiting
Measuring outcomes for creatine transporter deficiency
This study aims to find the best ways to measure how creatine transporter deficiency (CTD) affects people. It includes both males and females with CTD, as well as healthy volunteers, to compare results and develop better tests.
BronAges 2–60 - NCT07728240Recruiting
Diet, health, and exercise study
This study looks at how your diet and health affect your body's response to exercise. You'll do some thinking tests, record what you eat, and ride a bike at a moderate pace.
River Falls, WisconsinAges 18–60 - NCT07728279Enrolling by invitation
Breathing muscle training and brain health in older adults
This study tests whether a special breathing muscle exercise program can improve thinking and memory in adults aged 60 and older. If you are generally healthy and can walk and communicate on your own, you may be able to join.
Istanbul, IstanbulAges 60 years+ - NCT06466642Recruiting
Brain training for memory and thinking with HIV
This study tests if two types of computer-based brain exercises can help improve memory, thinking, and daily function in people living with HIV who have mild mental slowdowns. Participants will do about 10 hours of one brain game and 10 sessions of another over 5 weeks.
Cape Town, Western CapeAges 30–50 - NCT06446089Recruiting
Thinking Health program for Chinese pregnant immigrants in Canada
This study tests a mobile app-based mental health program designed for Chinese immigrant pregnant women in Canada. The app offers short 'talking therapy' sessions to help manage stress and emotional well-being during pregnancy.
Kingston, OntarioAges 18 years+ - NCT06374433Recruiting
How the brain learns: a brain stimulation study
This study explores how the brain learns and adapts (called brain plasticity) using a non-invasive brain stimulation technique. It may help understand learning and perception in healthy young adults.
MilanAges 18–35 - NCT06354790Recruiting
LAMA2-related dystrophy natural history study in children
This study follows children with LAMA2-related muscular dystrophy to learn how the condition changes over time. It does not test a new treatment, but helps researchers understand the disease better.
GarchesAges 2–15 - NCT07646509Recruiting
Mobile app to reduce physical symptoms from stress
This study tests a smartphone app designed to help people with somatic symptom disorder—a condition where stress and emotional distress cause ongoing physical symptoms that don't have a clear medical explanation. The app sends you check-ins and guidance throughout your day to help reduce these symptoms.
Vienna, State of ViennaAges 18–65 - NCT06127667Recruiting
Balance, brain health, and aging
This study looks at how your brain and blood vessels work together to keep you balanced as you age. It may help researchers understand why some people stay steady on their feet and others don't.
Minneapolis, MinnesotaAges 21–95 - NCT04151693Recruiting
Group therapy for chronic fatigue syndrome
This trial tests a health-psychology–based rehabilitation program delivered in a group setting for people with chronic fatigue syndrome (ME/CFS). It may help by teaching strategies to cope with symptoms and improving daily functioning through structured group support.
LahtiAges 18–65 - NCT07021001Recruiting
School program to prevent mental health issues in teens
This study tests a school program to help teens build emotional skills and prevent mental health problems. It is open to all students in certain grades, with no health exclusions.
CoimbraAges 11–18 - NCT07040904Recruiting
Mindfulness to help older Latino adults stay mentally sharp
This study tests whether mindfulness training can help older Latino adults stay sharp as they age. Researchers will measure changes in thinking skills and brain health.
St Louis, MissouriAges 65 years+ - NCT07724132RecruitingPhase 3
Treatments for sustained response in Alzheimer's disease
This study tests whether a treatment (atomoxetine or metformin) can help people with Alzheimer's disease maintain an improved state for at least 18 months. It may help you or a loved one stabilize symptoms and slow disease progression.
CambridgeAges 55 years+ - NCT06137339Recruiting
Daily avocado and cognition in older adults
This study tests whether eating one avocado daily for 6 months can help keep your thinking and memory sharp as you age. You must not currently eat many avocados or vegetables, and be willing to change your diet.
Kansas City, KansasAges 65–85 - NCT06108336Recruiting
How the cerebellum affects thinking and sequencing
This study uses MRI and TMS to understand how the cerebellum, a brain region, helps with cognitive sequencing—putting thoughts or actions in order. It may lead to better treatments for cognitive problems.
Baltimore, MarylandAges 18–50 - NCT07258355Enrolling by invitation
Fall prevention program for older adults
This study is testing a program that combines everyday activities (like dressing or cooking) with other measures to reduce falls in older adults. If you're 65+, have fallen recently, and don't have certain health issues, this trial might help you stay safer at home.
AnkaraAges 65 years+ - NCT06094218Recruiting
Developing a suicide prevention tool for active duty members
This study is for active duty service members who are getting mental health care and have had recent suicidal thoughts. The goal is to develop a tool that helps predict how well treatments may work for preventing suicide, so you and your provider can make better decisions.
Columbus, OhioAges 18 years+ - NCT07623785Recruiting
Beef and Brain Health in Older Adults
This study looks at whether eating lean beef and dairy products daily affects brain health markers in people 65 and older. Researchers will track blood, urine, and other samples to see if beef consumption influences how your brain functions at the molecular level.
Brookings, South DakotaAges 65 years+ - NCT07637331Recruiting
Breathing Exercises and Brain Performance Study
This study tests whether special breathing muscle exercises can improve thinking and memory in healthy young adults. Researchers will track how the training affects your brain performance over time.
Bloomington, IndianaAges 18–40 - NCT07572968Recruiting
Walking and Balance Tests for Older Adults with Memory Concerns
This study looks at how older adults walk and balance when doing two tasks at once (like talking while walking). Researchers want to understand how mild memory concerns affect movement, which could help catch early brain changes.
Balıkesir, BigadiçAges 65 years+
Hear when a new Cognition trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for cognition?
- Yes. Clin2 currently lists 2,028 recruiting cognition studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognition trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognition trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.