Clinical trials
Cognition clinical trials
Below are recruiting cognition clinical trials, each written for real people, not researchers. We’re tracking 1,981 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07648498Recruiting
Handgrip exercise for blood pressure and brain health in older adults
This study tests a simple handgrip exercise program (squeezing a device) done in the community to see if it can help lower blood pressure and improve thinking/memory in older adults. It is open only to people already at the Physical Activity Centre of Excellence at McMaster University.
Hamilton, OntarioAges 65 years+ - NCT07652892Recruiting
Fatty Liver, Memory, and Health in Men and Women
This study looks at how fatty liver disease (related to metabolism) affects memory, strength, and quality of life—especially comparing men and women. It helps understand why some people with fatty liver feel more tired or have trouble thinking clearly.
Barcelona, BarcelonaAges 20–80 - NCT06290024Recruiting
Nerve pain study: tracking long-term symptoms
This study follows people with nerve pain over time to learn more about their condition. You will not receive a new treatment, but your data will help doctors understand neuropathic pain better.
Shanghai, YangpuAges 18–85 - NCT06419101Recruiting
Finding early signs of memory loss in China
This trial looks for new ways to diagnose memory and thinking problems earlier. It involves a memory test, brain scan, and blood draw to find markers that could help identify cognitive disorders.
BeijingAges 40–90 - NCT07641075Recruiting
High-Dose Vitamin D Effects in Experienced Athletes
This study tests whether high-dose vitamin D supplements improve athletic performance, brain function, and body composition in experienced athletes. Researchers will measure hormones, muscle strength, thinking ability, and muscle mass over time.
Katowice, Mikołowska 72aAges 17–60 - NCT07641569Recruiting
Dual-Task Training Methods for Parkinson's Disease
This study compares two different training approaches that combine cognitive (thinking) and physical exercises to help improve balance, walking, and daily functioning in people with Parkinson's disease. The goal is to find which method works better for maintaining independence and preventing falls.
Ankara, KeçiörenAges 40 years+ - NCT07641153Recruiting
Virtual Reality Games to Prevent Confusion After Surgery
This study tests whether playing cognitive games in virtual reality (VR—a computer-generated environment you interact with using a headset) can help prevent delirium (severe confusion) in older adults after major surgery. Delirium is common after surgery in seniors and can slow recovery; this trial explores whether VR brain exercises might reduce it.
Houston, TexasAges Up to 65 years - NCT07646054Enrolling by invitation
Lifestyle coaching for preventing Alzheimer's in APOE4 carriers
This study tests a digital lifestyle coaching program designed to help prevent Alzheimer's disease in people who carry the APOE4 genetic variant, which increases risk. Over one year, you'll get personalized health coaching through apps and possibly a smart ring to track your progress.
La Jolla, CaliforniaAges 60–80 - NCT06685380Recruiting
Cognitive Control During Sleep: Self-Awakening Study
This study looks at how our brains control waking up on purpose during sleep. It may help people who can train themselves to wake up at specific times.
Milan, ItalyAges 18–65 - NCT07633470RecruitingPhase 4
Zunveyl for Alzheimer's disease symptoms and caregiver support
This study tests a medication called Zunveyl to see if it helps reduce behavioral and neuropsychiatric symptoms in people with mild-to-moderate Alzheimer's disease, and whether it reduces stress on family caregivers. You would need a confirmed Alzheimer's diagnosis supported by a blood test, and a dedicated caregiver who can attend visits and report on your symptoms.
Irvine, CaliforniaAges 50 years+ - NCT07634055Recruiting
Motor Reserve in Early Dementia Stages
This study compares how the brain controls movement in people with mild memory loss (MCI) versus healthy people. Researchers want to understand how the brain compensates early on, which could help identify who might develop dementia.
Catanzaro, CatanzaroAges 18–85 - NCT07637331Recruiting
Breathing Exercises and Brain Performance Study
This study tests whether special breathing muscle exercises can improve thinking and memory in healthy young adults. Researchers will track how the training affects your brain performance over time.
Bloomington, IndianaAges 18–40 - NCT05510401Recruiting
Safe use study of an at-bed safety mattress system
This study checks whether a special bed-safety device (SÉCURIDRAP® SELFIA®) can be used safely for adults who get confused, move at night, or are at risk of falling out of bed. You may be able to join if you already have a prescription for the device and meet other safety and consent requirements.
BailleulAges 18 years+ - NCT07622589Enrolling by invitation
How stress affects your body during market and news volatility
This study tracks how financial market changes, work stress, and news exposure affect your body's stress response using a wearable device and smartphone app. Researchers want to understand the connection between stress and physical health markers during uncertain times.
New York, New YorkAges 18 years+ - NCT07625241Recruiting
Brain and Movement Training for Mild-to-Moderate Dementia
This study tests two types of training—cognitive (brain) and movement exercises—for people with mild-to-moderate dementia. The goal is to see if these activities together can help improve thinking, memory, and physical function.
Genova, GenovaAges 65 years+ - NCT07624747Recruiting
Brain Health Study for Transgender Adults Starting Hormone Therapy
This study looks at how gender-affirming hormone therapy affects brain health and function in transgender adults. Researchers want to understand the effects of these hormones on the brain before and after treatment begins.
Madison, WisconsinAges 18–45 - NCT07623785Recruiting
Beef and Brain Health in Older Adults
This study looks at whether eating lean beef and dairy products daily affects brain health markers in people 65 and older. Researchers will track blood, urine, and other samples to see if beef consumption influences how your brain functions at the molecular level.
Brookings, South DakotaAges 65 years+ - NCT06702488RecruitingPhase 1
Dexmedetomidine and magnesium to protect thinking after surgery in seniors
This study tests whether adding two drugs, dexmedetomidine and magnesium sulfate, during anesthesia can help older adults keep their thinking and memory sharp after open abdominal surgery. It aims to reduce the risk of confusion or memory problems that sometimes happen after surgery.
Al FayyumAges 60–80 - NCT06567145Recruiting
Group therapy for self-stigma in mental health
This study tests a group therapy program designed to help people with mental health conditions reduce the shame and stigma they feel about their illness. It takes place in northeastern Italy and is for people who are stable on their current medications.
VeronaAges 18 years+ - NCT06704451Recruiting
IL-33 and memory after major abdominal surgery
This study looks at whether a protein called IL-33 is linked to memory and thinking problems that can happen after major abdominal surgery. It may help doctors find patients at risk earlier.
Kunming, YunnanAges Any age - NCT07615478Recruiting
Hot spring therapy for reducing fatigue during altitude rowing training
This study tests whether soaking in hot springs can help young rowers feel less tired and recover better while training at high altitude. Researchers want to see if the hot water helps the body's natural fatigue-fighting systems work better.
Macao, MacaoAges 12–16 - NCT07615257Recruiting
Mindfulness and CBT for Psoriasis-Related Emotional Stress
This study tests whether a combination of mindfulness and cognitive behavioral therapy (CBT)—talk-based techniques to manage thoughts and emotions—can help psoriasis patients feel less stressed and more compassionate toward themselves. Participants attend sessions over several weeks to learn these skills.
Rahim Yar Khan, Punjab ProvinceAges 25–75 - NCT07619092Recruiting
Flumazenil to reverse sedation during depression treatment
This trial tests whether flumazenil (a medication that reverses sedation from anti-anxiety drugs) can safely help patients wake up faster after electroconvulsive therapy (ECT), a treatment for severe depression. The goal is to see if it improves recovery time without causing problems.
Frederiksberg, Capital RegionAges 18 years+ - NCT06703320Recruiting
Virtual reality pathfinding study for stroke recovery
This study uses a virtual reality pathfinding game to see how your brain activates after a stroke. It may help doctors understand how to improve recovery.
Chongqing, Chongqing MunicipalityAges 18–80
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Common questions
- Are there clinical trials for cognition?
- Yes. Clin2 currently lists 1,981 recruiting cognition studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognition trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognition trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.