Clinical trials
Cognitive Dysfunction clinical trials
Below are recruiting cognitive dysfunction clinical trials, each written for real people, not researchers. We’re tracking 145 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07523113Recruiting
Brain Fog Treatment for ME/CFS Using Cognitive Training
This study tests whether a computerized cognitive training program combined with a mild electrical nerve stimulation device (worn on the ear) can help improve thinking and memory problems in people with ME/CFS. The goal is to see if this approach helps with brain fog and daily functioning.
Birmingham, AlabamaAges 18 years+ - NCT07802392Recruiting
Virtual nature program for older adults with memory problems
This study tests a virtual reality nature program designed to improve wellbeing in older adults with mild to moderate memory problems. If you enjoy nature and can use a virtual reality headset, this program might be a relaxing and enjoyable addition to your routine.
Terrassa, BarcelonaAges 65 years+ - NCT05273125Recruiting
Testing mobility and thinking in people with mild cognitive problems
This study looks at how well people with mild cognitive problems can think and move, using brief learning/thinking tests and a walking task. It may help researchers understand changes early enough to guide future care.
LilleAges 65 years+ - NCT06951919Recruiting
HOBSCOTCH study for memory help in MS
This trial tests a program called HOBSCOTCH to help people with MS who have memory or thinking problems. It also includes a caregiver who supports them.
Lebanon, New HampshireAges 20–75 - NCT06442943Recruiting
Digital brain training for people at risk of dementia
This trial tests a digital program designed to improve memory and thinking skills in people who are at high risk for dementia but do not yet have dementia.
Fuzhou, FujianAges 55 years+ - NCT06936397Recruiting
Cognitive therapy for schizophrenia: Brain changes and emotions
This trial tests a cognitive training program for people with schizophrenia to see if it improves thinking and emotional control, and how it affects brain activity measured by EEG.
IstanbulAges 18–55 - NCT06672367Recruiting
Balance and gaze exercises for brain health in older adults
This study looks at whether adding gaze stability exercises (eye and head movements) to balance training can improve thinking, balance, and walking steadiness in older adults with mild memory problems. It may help those who can follow simple instructions and join in physical activity.
IslamabadAges 55 years+ - NCT07073781Recruiting
Probiotics for Brain & Blood Sugar in Overweight Young Adults
This study tests whether taking a probiotic (a 'good bacteria' supplement) can help brain function (thinking, memory) and improve blood sugar control in overweight adults who have higher-than-normal blood sugar. If you're between 18-40, overweight, and don't have diabetes, you may be able to join.
Leeds, Greater ManchesterAges 18–40 - NCT06679296Recruiting
Aging and Memory Loss Study in China
This study looks at how aging affects memory and thinking. It uses brain scans, a spinal tap, and other tests to understand cognitive decline better.
Wenzhou, ZhejiangAges Any age - NCT06579677Recruiting
Watching small blood vessels in the brain over time
This study watches how small blood vessels in the brain change over time. It may help doctors understand brain health as people age.
Beijing, Beijing MunicipalityAges 50–75 - NCT04610697Recruiting
Cognitive training for people in forensic mental health care
This trial studies whether a structured “cognitive remediation” program (training thinking skills) can help people receiving care on a forensic treatment unit. It may benefit those who want support improving attention, memory, or problem-solving as part of their treatment.
Ottawa, OntarioAges 18–55 - NCT07358598Recruiting
Eye movement and thinking in older adults
This study looks at how eye movements relate to thinking abilities in people aged 65 and older. It may help understand how the brain changes with age.
Kaohsiung CityAges 65 years+ - NCT07114809Recruiting
Can brain stimulation and virtual reality boost thinking in MS?
This study tests whether a combination of gentle brain stimulation (tDCS) and virtual reality exercises can improve memory and thinking problems in people with multiple sclerosis. If you have mild to moderate disability and no major health issues, you may be able to join.
Genova, ItalyAges 18–65 - NCT05667857Recruiting
Tracking brain, mood, and quality of life after immunotherapy
This study follows people who have had advanced cancer and are now stable after immunotherapy, to see how thinking, mood, and daily life change over time. Some participants may also do an integrative brain-training program if they have memory or thinking problems.
Brussels, Brussels CapitalAges 18 years+ - NCT06930846Recruiting
Brain cancer cognitive training study
This study tests a home-based program called HOBSCOTCH-CA to help with memory and thinking problems after brain cancer treatment. The program uses phone and internet sessions to teach self-management skills.
Lebanon, New HampshireAges 18 years+ - NCT07589595RecruitingPhase 2
Donanemab for Early Cognitive Decline with Lewy Bodies
This study tests donanemab, an investigational drug designed to target amyloid proteins in the brain that may contribute to cognitive decline in people with early dementia with Lewy bodies. The trial aims to see if this treatment can slow cognitive decline and help preserve thinking and memory.
Chandler, ArizonaAges 55–85 - NCT07452367Recruiting
Bentall surgery study: optic nerve and thinking ability
This study checks if swelling of the optic nerve sheath during heart surgery with a bypass machine is linked to changes in thinking ability after the operation. It may help understand why some people have mental fogginess after surgery.
Bursa, YıldırımAges 18–80 - NCT07418008Recruiting
Thinking and memory study for people with liver cirrhosis
This study is creating a new test to measure thinking and memory problems in people with liver cirrhosis. It may help doctors find these problems earlier.
Ambāla, HaryanaAges 18–75 - NCT07392723RecruitingPhase 2
Flaxseed nutrition to protect memory in APOE4 adults
This study tests a special flaxseed-based nutrition drink to see if it can slow memory loss in older adults who have the APOE4 gene and mild cognitive impairment (early memory trouble). If you qualify, you'll take the drink daily for a year and have memory tests and brain scans.
New Brunswick, New JerseyAges 60 years+ - NCT07113483RecruitingPhase 3
Remimazolam vs. Midazolam for sedation in older adults having orthopedic surgery
This trial compares two sedatives, remimazolam and midazolam, to see which one leads to better recovery of thinking skills after orthopedic surgery. It is for people aged 65 and older who are having surgery on a bone or joint while awake but relaxed.
BucharestAges 65 years+ - NCT07531888Enrolling by invitation
Brain Stimulation to Improve Memory in Older Adults
This study tests whether a non-invasive brain stimulation technique (tDCS) can help improve memory and thinking skills in people aged 60–75 who have noticed mild memory problems. You'll receive either real or sham (placebo) stimulation and undergo cognitive training over several weeks.
Pachuca, HidalgoAges 60–75 - NCT07638007Recruiting
How targeted therapy affects thinking and memory in blood cancer
This study examines whether a new type of cancer medication affects thinking, memory, and focus in people with chronic myeloid leukemia (CML) or chronic lymphocytic leukemia (CLL). Researchers will compare people starting this medication with healthy volunteers to understand any changes.
Rochester, New YorkAges 18 years+ - NCT07750223Recruiting
Hesperidin for memory and thinking in older adults
This study tests whether a natural supplement called hesperidin (found in citrus fruits) can support brain health in older adults who are overweight or obese. It may help with memory and thinking.
Shanghai, Shanghai MunicipalityAges 55–75 - NCT07054723Recruiting
Surviving daily life after breast cancer
This study looks at how breast cancer survivors manage daily life. Researchers want to learn from people who are 40 or older and at least 5 years past their diagnosis. The goal is to better understand what helps people thrive after cancer.
Philadelphia, PennsylvaniaAges 40 years+
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Common questions
- Are there clinical trials for cognitive dysfunction?
- Yes. Clin2 currently lists 145 recruiting cognitive dysfunction studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognitive dysfunction trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognitive dysfunction trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.