Clinical trials
Cognitive Dysfunction clinical trials
Below are recruiting cognitive dysfunction clinical trials, each written for real people, not researchers. We’re tracking 152 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07531888Enrolling by invitation
Brain Stimulation to Improve Memory in Older Adults
This study tests whether a non-invasive brain stimulation technique (tDCS) can help improve memory and thinking skills in people aged 60–75 who have noticed mild memory problems. You'll receive either real or sham (placebo) stimulation and undergo cognitive training over several weeks.
Pachuca, HidalgoAges 60–75 - NCT07304843RecruitingPhase 1/Phase 2
Testing golexanolone for fatigue and brain fog in PBC
This study tests an experimental drug called golexanolone to see if it can help with fatigue and thinking problems in people with primary biliary cholangitis (PBC). It involves taking two different doses of the drug and checking how you feel and think over time.
DüsseldorfAges 18 years+ - NCT07638007Recruiting
How targeted therapy affects thinking and memory in blood cancer
This study examines whether a new type of cancer medication affects thinking, memory, and focus in people with chronic myeloid leukemia (CML) or chronic lymphocytic leukemia (CLL). Researchers will compare people starting this medication with healthy volunteers to understand any changes.
Rochester, New YorkAges 18 years+ - NCT07750223Recruiting
Hesperidin for memory and thinking in older adults
This study tests whether a natural supplement called hesperidin (found in citrus fruits) can support brain health in older adults who are overweight or obese. It may help with memory and thinking.
Shanghai, Shanghai MunicipalityAges 55–75 - NCT07054723Recruiting
Surviving daily life after breast cancer
This study looks at how breast cancer survivors manage daily life. Researchers want to learn from people who are 40 or older and at least 5 years past their diagnosis. The goal is to better understand what helps people thrive after cancer.
Philadelphia, PennsylvaniaAges 40 years+ - NCT07637357Recruiting
How anesthesia affects thinking after weight-loss surgery
This study looks at how different types of anesthesia used during sleeve gastrectomy (a weight-loss surgery) may affect your memory and thinking skills after the operation. Researchers want to understand which anesthesia approach is safest for your brain.
Istanbul, SancaktepeAges 18–65 - NCT07657624Recruiting
Heart disease and memory problems risk study
This study looks at what factors might increase the risk of memory and thinking problems in people with coronary heart disease. It includes testing your memory and metabolism during a hospital stay.
Beijing, ChinaAges 18 years+ - NCT05036538Recruiting
Reducing pre-surgery stress to help prevent confusion after heart surgery
This study tests whether a stress-reducing relaxation method before heart surgery can lower the risk of postoperative delirium (sudden confusion) and longer-term thinking problems. It may help you keep clearer thinking in the days and weeks after surgery.
Bad Nauheim, HesseAges 18 years+ - NCT07128186Recruiting
AI predicts memory decline in type 2 diabetes
This study uses an AI tool to predict memory problems in people with type 2 diabetes. It may help catch early signs of cognitive decline and guide future care.
Enshi, HubeiAges 40–75 - NCT05356611Recruiting
Study for depression and mild memory thinking problems
This trial tests a program aimed at helping older adults with depression who also have mild thinking and memory difficulties. You may be asked to complete study sessions and tracking, with support for depression symptoms and thinking function.
Las Vegas, NevadaAges 60 years+ - NCT04109027Recruiting
Training program to improve thinking and memory for veterans
This trial tests an intensive skills-training program to help with thinking and memory problems after a mild-to-moderate traumatic brain injury (TBI). It’s designed for veterans who are at least 6 months past the injury and still notice cognitive symptoms that affect daily goals like work or school.
Sacramento, CaliforniaAges 21–60 - NCT04938362Recruiting
Study brain recovery after abscess using memory and brain scans
This study looks at how thinking and energy levels change after a brain abscess. It may help researchers understand what affects recovery and fatigue, using thinking tests and brain imaging/brain-wave checks.
OsloAges 16 years+ - NCT05555693Recruiting
Brain chemistry study after surgery in older adults
This study looks at how brain “metabolomics” (small chemical signals in the brain/body) relate to thinking or mood problems that can happen after surgery in people age 65 and older. It may help doctors understand who is more likely to have these side effects after an operation.
Shanghai, Shanghai MunicipalityAges 65 years+ - NCT05830942Recruiting
Training walks plus brain stimulation for thinking skills in older adults
This study tests whether a structured walking exercise, combined with brain stimulation and brain scans, can improve or slow decline in thinking skills. It’s aimed at older adults who notice memory or confusion getting worse.
Gainesville, FloridaAges 65 years+ - NCT03542734Recruiting
Imaging study for thinking and brain changes in older adults
This study looks at brain scans and eye/eye-nerve findings to understand why thinking can change with aging. It may help researchers connect eye and brain changes, which could guide future ways to prevent or detect dementia early.
HangzhouAges 40 years+ - NCT06040905Recruiting
Coenzyme Q10 for cognitive decline with high blood sugar and muscle loss
This trial tests whether Coenzyme Q10 supplements help people with mild memory loss or Alzheimer's who also have high blood sugar and early muscle weakness. It aims to see if CoQ10 can improve thinking and daily function.
TaichungAges 50–80 - NCT06799481Recruiting
Home-based exercise to help brain tumor survivors with thinking and memory
This study tests whether a virtual home-based exercise program can improve thinking and memory problems caused by brain tumor treatment in teens and young adults. It also looks at how exercise affects gut health.
Atlanta, GeorgiaAges 15–39 - NCT07010536Recruiting
Virtual reality music therapy for stroke recovery
This study tests whether combining virtual reality games with music therapy can help improve thinking and movement skills in people who had a stroke within the last 6 months. It may be a good option if you are between 50 and 75 and can sit up and use your hearing and vision.
Istanbul, IstanbulAges 50–75 - NCT07193823Recruiting
Sexual function study for women with MS
This study looks at sexual health in women with relapsing-remitting multiple sclerosis. It aims to understand how MS might affect sexual function and to find ways to help.
Izmir, BornovaAges 25–50 - NCT05445180Recruiting
Brain scan study of thinking in cannabis users with psychosis
This study uses brain imaging to understand how thinking works in people who use cannabis, comparing those with psychosis to people without psychosis. It may help researchers learn what brain patterns relate to thinking difficulties and how cannabis use fits in.
Montreal, QuebecAges 16–80 - NCT07633626Recruiting
Vortioxetine for thinking problems from ALK lung cancer treatment
This trial tests whether a medication called vortioxetine can help improve memory, focus, and thinking problems caused by lorlatinib, a drug used to treat ALK-positive lung cancer. You would take vortioxetine alongside your current cancer treatment to see if it helps your brain function.
BogotáAges 18 years+ - NCT04816006Recruiting
Breast cancer, thinking, and exercise study
This trial tests whether exercise can help thinking and reasoning in women over 50 who have had early-stage breast cancer. It compares a moderate exercise program with health education sessions.
Phoenix, ArizonaAges 50 years+ - NCT07730957Recruiting
Music program to reduce care refusal in nursing home residents
This trial tests whether a structured music program can help reduce care refusal (like agitation or aggression during bathing) in nursing home residents with memory or thinking problems. Residents who show these behaviors may be eligible.
AmiensAges 18 years+ - NCT07220512Recruiting
Exercise help for ovarian, fallopian, or endometrial cancer
This trial tests a special exercise program during chemotherapy before surgery. It may help patients with certain gynecologic cancers get stronger and better prepared for treatment.
Winston-Salem, North CarolinaAges 55 years+
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Common questions
- Are there clinical trials for cognitive dysfunction?
- Yes. Clin2 currently lists 152 recruiting cognitive dysfunction studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognitive dysfunction trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognitive dysfunction trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.