Clinical trials
Cognitive Dysfunction clinical trials
Below are recruiting cognitive dysfunction clinical trials, each written for real people, not researchers. We’re tracking 145 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07637357Recruiting
How anesthesia affects thinking after weight-loss surgery
This study looks at how different types of anesthesia used during sleeve gastrectomy (a weight-loss surgery) may affect your memory and thinking skills after the operation. Researchers want to understand which anesthesia approach is safest for your brain.
Istanbul, SancaktepeAges 18–65 - NCT07657624Recruiting
Heart disease and memory problems risk study
This study looks at what factors might increase the risk of memory and thinking problems in people with coronary heart disease. It includes testing your memory and metabolism during a hospital stay.
Beijing, ChinaAges 18 years+ - NCT07128186Recruiting
AI predicts memory decline in type 2 diabetes
This study uses an AI tool to predict memory problems in people with type 2 diabetes. It may help catch early signs of cognitive decline and guide future care.
Enshi, HubeiAges 40–75 - NCT05036538Recruiting
Reducing pre-surgery stress to help prevent confusion after heart surgery
This study tests whether a stress-reducing relaxation method before heart surgery can lower the risk of postoperative delirium (sudden confusion) and longer-term thinking problems. It may help you keep clearer thinking in the days and weeks after surgery.
Bad Nauheim, HesseAges 18 years+ - NCT04938362Recruiting
Study brain recovery after abscess using memory and brain scans
This study looks at how thinking and energy levels change after a brain abscess. It may help researchers understand what affects recovery and fatigue, using thinking tests and brain imaging/brain-wave checks.
OsloAges 16 years+ - NCT04109027Recruiting
Training program to improve thinking and memory for veterans
This trial tests an intensive skills-training program to help with thinking and memory problems after a mild-to-moderate traumatic brain injury (TBI). It’s designed for veterans who are at least 6 months past the injury and still notice cognitive symptoms that affect daily goals like work or school.
Sacramento, CaliforniaAges 21–60 - NCT05555693Recruiting
Brain chemistry study after surgery in older adults
This study looks at how brain “metabolomics” (small chemical signals in the brain/body) relate to thinking or mood problems that can happen after surgery in people age 65 and older. It may help doctors understand who is more likely to have these side effects after an operation.
Shanghai, Shanghai MunicipalityAges 65 years+ - NCT05830942Recruiting
Training walks plus brain stimulation for thinking skills in older adults
This study tests whether a structured walking exercise, combined with brain stimulation and brain scans, can improve or slow decline in thinking skills. It’s aimed at older adults who notice memory or confusion getting worse.
Gainesville, FloridaAges 65 years+ - NCT03542734Recruiting
Imaging study for thinking and brain changes in older adults
This study looks at brain scans and eye/eye-nerve findings to understand why thinking can change with aging. It may help researchers connect eye and brain changes, which could guide future ways to prevent or detect dementia early.
HangzhouAges 40 years+ - NCT06799481Recruiting
Home-based exercise to help brain tumor survivors with thinking and memory
This study tests whether a virtual home-based exercise program can improve thinking and memory problems caused by brain tumor treatment in teens and young adults. It also looks at how exercise affects gut health.
Atlanta, GeorgiaAges 15–39 - NCT07087951Recruiting
Sound therapy for memory loss in older adults
This study tests whether listening to a special sound (gamma-frequency tones) can help slow down memory loss in older adults. It's for people who have mild memory problems but not dementia or other brain disorders.
Taoyuan, GuishanAges 60 years+ - NCT07193823Recruiting
Sexual function study for women with MS
This study looks at sexual health in women with relapsing-remitting multiple sclerosis. It aims to understand how MS might affect sexual function and to find ways to help.
Izmir, BornovaAges 25–50 - NCT05445180Recruiting
Brain scan study of thinking in cannabis users with psychosis
This study uses brain imaging to understand how thinking works in people who use cannabis, comparing those with psychosis to people without psychosis. It may help researchers learn what brain patterns relate to thinking difficulties and how cannabis use fits in.
Montreal, QuebecAges 16–80 - NCT07633626Recruiting
Vortioxetine for thinking problems from ALK lung cancer treatment
This trial tests whether a medication called vortioxetine can help improve memory, focus, and thinking problems caused by lorlatinib, a drug used to treat ALK-positive lung cancer. You would take vortioxetine alongside your current cancer treatment to see if it helps your brain function.
BogotáAges 18 years+ - NCT04523909Recruiting
Testing spinal fluid inflammation changes after aortic surgery
This study tracks inflammation-related lab markers in spinal fluid taken through a temporary drain during and after thoracic aortic surgery. It may help doctors understand what inflammatory changes happen around surgery and how they relate to recovery.
NijmegenAges 18 years+ - NCT05483166Recruiting
Parent coaching to support memory and behavior after childhood cancer
This pilot study tests a program that works with parents to support a child’s thinking, memory, and behavior after childhood cancer treatment. It may help by teaching parents strategies to support school and day-to-day functioning.
AarhusAges 10–17 - NCT07871487Recruiting
Brain protein changes after hip or knee replacement surgery
This study looks at whether having hip or knee replacement surgery with spinal anesthesia affects certain proteins in the brain that are linked to memory and thinking. It compares people having surgery with people who have arthritis but are not having surgery, to help understand if the surgery causes any short-term brain changes.
UppsalaAges 55–75 - NCT06036095RecruitingPhase 4
Comparing two types of anesthesia in older adults having surgery
This study compares two types of general anesthesia for older adults (70+) having planned non-heart, non-brain surgery that lasts at least 2 hours. The goal is to see which type might be better for preserving thinking and memory after surgery.
Portland, OregonAges 70–110 - NCT07808619Recruiting
AI health data study for adults
This study is collecting health data to train an AI system that may help predict or improve health outcomes. By joining, you help develop technology that could benefit patients in the future.
Boulder, ColoradoAges 18 years+ - NCT07806487Enrolling by invitation
Eye-tracking to predict confusion after surgery
This study uses eye-tracking technology to see if it can predict post-operative delirium in older adults after surgery. You will have your eye movements measured before and after surgery to help identify early signs of delirium.
Santiago, Santiago MetropolitanAges 70 years+ - NCT07730957Recruiting
Music program to reduce care refusal in nursing home residents
This trial tests whether a structured music program can help reduce care refusal (like agitation or aggression during bathing) in nursing home residents with memory or thinking problems. Residents who show these behaviors may be eligible.
AmiensAges 18 years+ - NCT07669168Recruiting
Health study comparing usual care vs. extra support
This study looks at whether adding extra health support helps people stay healthier over time. You would be followed for a while and asked to share how you are doing.
Boulder, ColoradoAges 18 years+ - NCT06469515Recruiting
Thinking recovery after heart surgery in older adults
This study looks at how older adults recover their thinking and memory skills after heart surgery. You may be asked to do simple computer or paper tests to see how your brain heals.
GothenburgAges 65 years+ - NCT07646782Recruiting
Human Observatory Study: Aging and Longevity Research
This study observes how people age over time to better understand what helps people live longer and healthier lives. You'll share health information through surveys or online screening, and researchers will track changes in your health and wellbeing.
Boulder, ColoradoAges 18 years+
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Common questions
- Are there clinical trials for cognitive dysfunction?
- Yes. Clin2 currently lists 145 recruiting cognitive dysfunction studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognitive dysfunction trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognitive dysfunction trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.