Clinical trials
Cognitive Training clinical trials
Below are recruiting cognitive training clinical trials, each written for real people, not researchers. We’re tracking 292 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07190404Recruiting
Thinking skills program for Parkinson's disease
This study tests a program to help people with Parkinson's disease who are noticing problems with their memory or thinking. The program teaches strategies to manage daily thinking challenges.
St Louis, MissouriAges 50 years+ - NCT06874764Enrolling by invitation
Training with a wireless system for thinking and reaction in MS
This study tests whether a special wireless reaction training system can help improve thinking and reaction speed in people with multiple sclerosis (MS). It compares this training to standard exercises to see which works better for your brain health.
Izmir, BornovaAges 18–55 - NCT05042102RecruitingPhase 2
Donepezil plus brain training for alcohol use disorder
This Phase 2 study tests whether donepezil, along with structured cognitive (brain) training, can improve outcomes for people with alcohol use disorder. It will measure whether this combination helps after recent heavy drinking, while tracking safety over about 13 weeks.
West Haven, ConnecticutAges 18–80 - NCT07728279Enrolling by invitation
Breathing muscle training and brain health in older adults
This study tests whether a special breathing muscle exercise program can improve thinking and memory in adults aged 60 and older. If you are generally healthy and can walk and communicate on your own, you may be able to join.
Istanbul, IstanbulAges 60 years+ - NCT06772831Recruiting
Cognitive reappraisal training for borderline personality
This study tests a thinking strategy called 'cognitive reappraisal training' for people with borderline personality disorder (BPD). The goal is to see if this training helps manage emotions and symptoms related to BPD.
New York, New YorkAges 18–55 - NCT06338774Recruiting
Can cognitive training boost physical activity in midlife adults?
This study tests whether combining cognitive training with aerobic exercise can help 'low active' adults aged 40–65 become more physically active. Participants will do both brain games and exercise to see if this combo improves adherence.
Iowa City, IowaAges 40–65 - NCT06853405Recruiting
Nutrition program to prevent memory decline
This study tests whether nutrition-based changes can help prevent memory loss and thinking problems in people who are at higher risk for dementia. To join, you need to be between 55 and 85, have at least 4 years of schooling, and have an elevated dementia risk score.
Porto, PortugalAges 55–85 - NCT07603102Recruiting
Mindfulness and Walking Training for Memory After Stroke
This study tests whether combining mindfulness meditation with balance and walking exercises can help improve memory and thinking skills in people who had a stroke. The trial focuses on people with mild cognitive impairment—difficulty thinking clearly—after stroke recovery.
NanjingAges 55 years+ - NCT07167719Recruiting
Resilience training for parolees with adjustment challenges
This study tests a cognitive-behavioral training program to help people on parole build resilience and cope with adjustment difficulties. If you are recently on parole and having trouble adjusting, this program may offer tools to support your mental health.
Los Angeles, CaliforniaAges 18 years+ - NCT05014893Recruiting
Brain testing and rehab study for thinking changes
This study looks at how brain activity relates to thinking problems and whether a cognitive (thinking) assessment and rehab approach can help adults with memory or thinking changes. You may be asked to take thinking tests and complete study activities during rehab.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07144930Recruiting
Cognitive-motor training for stroke and Moyamoya disease
This trial tests a combined thinking and movement training program for people who have had a stroke or have Moyamoya disease and still have some thinking or movement problems. It may help improve both mental and physical abilities.
TaipeiAges 20–100 - NCT06219304Recruiting
High intensity training for multiple sclerosis
This trial tests whether high intensity exercise can improve both movement and thinking in people with multiple sclerosis. It might help if you can walk but need some support for balance.
Milan, MIAges 18 years+ - NCT04962061Recruiting
Multidomain program to help prevent memory decline
This trial tests a combined lifestyle/health program to help prevent thinking and memory problems in older adults with cardiovascular risk factors. It may help by improving activity, health habits, and overall brain health over time.
Montreal, QuebecAges 60 years+ - NCT06323278Recruiting
Thinking and memory training for Parkinson's disease
This study tests whether a thinking-and-memory training program (cognitive stimulation) can help people with Parkinson's who have mild memory or thinking problems, but not dementia. You must not have had deep brain stimulation surgery.
MilanAges 18–80 - NCT06974890Recruiting
Balance training for children with mild cognitive impairment
This study tests if special balance exercises can help improve walking, balance, and posture control in children with mild cognitive impairment. It may help your child move more confidently and safely.
Lahore, Punjab ProvinceAges 6–12 - NCT05380050Recruiting
Telehealth vs in-person skills training for brain injury and PTSD
This study compares a combined skills program delivered by video/phone (telehealth) versus meeting in person. It aims to improve attention and coping skills for veterans who have both mild brain injury and PTSD.
Gainesville, FloridaAges 30–55 - NCT07581587Recruiting
Breathing Exercises and Brain Function in Heart Failure
This study tests whether special breathing exercises—done alone or while doing a mental task—can improve memory and thinking skills in people with heart failure. Researchers want to see if training your breathing muscles helps your brain work better.
Istanbul, FatihAges 40 years+ - NCT07404085Recruiting
Cognitive training with medication for mood disorders
This trial tests if a medication can boost the effects of cognitive training in people with bipolar disorder or recurrent depression who have memory or thinking problems. It aims to improve daily functioning.
Frederiksberg, Capital Region of DenmarkAges 40–75 - NCT07147894Recruiting
Executive Function Training for Teens and Kids
This study tests a new type of training designed to help children and teens improve their executive function skills—things like planning, focus, and self-control. It is open to kids ages 12 to 17, especially those with ADHD, as long as they are not currently taking ADHD medication and have a parent who can join the training.
Boston, MassachusettsAges 12–17 - NCT06951919Recruiting
HOBSCOTCH study for memory help in MS
This trial tests a program called HOBSCOTCH to help people with MS who have memory or thinking problems. It also includes a caregiver who supports them.
Lebanon, New HampshireAges 20–75 - NCT07244536Recruiting
Exercise and brain training for better quality of life
This trial tests if combining physical exercise with cognitive (brain) training can improve quality of life in older adults. It may help you stay active and sharp as you age.
FerraraAges 70 years+ - NCT04414215Recruiting
Emotion-focused brain training for schizophrenia or schizoaffective disorder
This study tests a structured cognitive (thinking/skill) training program aimed at improving how people manage emotions. It may help by teaching emotion regulation skills alongside existing care.
Athens, GeorgiaAges 18–60 - NCT05236010Recruiting
Brain stimulation plus cognitive training for mild TBI memory and thinking
This trial studies whether brain stimulation through the scalp can improve cognitive (thinking and memory) training in people with chronic mild traumatic brain injury (TBI). Participants train on thinking tasks while receiving a targeted “control network neuromodulation” approach to see if it enhances training results.
Minneapolis, MinnesotaAges 18–59 - NCT06608797Recruiting
Computer-based cognitive training for multiple sclerosis patients
This study tests whether a computer-based cognitive training program is helpful and practical for people with multiple sclerosis who live in the community. It focuses on those who have some memory or learning difficulties.
East Hanover, New JerseyAges 19–65
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Common questions
- Are there clinical trials for cognitive training?
- Yes. Clin2 currently lists 292 recruiting cognitive training studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognitive training trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognitive training trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.