Clinical trials
Cognitive clinical trials
Below are recruiting cognitive clinical trials, each written for real people, not researchers. We’re tracking 2,033 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06245031Enrolling by invitation
Long-term follow-up of sensory stimulation for Alzheimer's
This is a follow-up study for people who already completed the 12-month Hope Study (CA-0011). It tests long-term safety and effects of a gentle sensory stimulation device (light and sound) for Alzheimer's disease. You will continue using the device at home with a study partner.
Phoenix, ArizonaAges 50–92 - NCT06029114Enrolling by invitation
Brain scan study for memory problems
This study uses a special MRI to look at brain stiffness in people with normal memory, mild memory problems, or Alzheimer's disease. The goal is to see if this scan can help tell the difference between these groups.
Rochester, MinnesotaAges 18–100 - NCT06017505Enrolling by invitation
Using eSAGE for early detection of cognitive decline
This study uses a simple computer-based self-assessment (eSAGE) to detect early signs of memory or thinking problems. It may help identify cognitive impairment sooner and track changes over time.
Columbus, OhioAges 50 years+ - NCT05830422Enrolling by invitation
Predicting late thinking problems after cardiac arrest
This study looks at how to predict delayed cognitive (thinking) impairment in people who survived a cardiac arrest but initially seemed neurologically okay. It may help identify who is at higher risk so follow-up and support can be planned earlier.
Daejeon, Seo-guAges 18 years+ - NCT05826379Enrolling by invitation
Daily goal setting to boost movement and brain health
This trial tests whether a daily goal-setting program and activity tracking can increase everyday physical activity and support thinking/brain health in midlife. You may be asked to wear devices and meet activity-monitoring requirements during the study.
Hershey, PennsylvaniaAges 30–70 - NCT05821634Enrolling by invitation
Personalized telehealth counseling for anxiety and alcohol use
This study personalizes how telehealth counseling is delivered for people dealing with anxiety or trauma-related symptoms and alcohol use problems. It may help by tailoring counseling timing and approach to what you need.
Piscataway, New JerseyAges 18–65 - NCT05448768Enrolling by invitation
Testing brain stimulation in people with mild memory problems
This study tests a brain stimulation approach (TBS) to see if it can improve thinking and memory in people with mild cognitive impairment. It may also explore why it works by looking at brain-related measurements after TBS.
TaoyuanAges 50–90 - NCT05371483Enrolling by invitation
Study effects of narcolepsy and hypersomnia treatments on brain and heart
This study looks at how narcolepsy or idiopathic hypersomnia affects thinking and cardiovascular health, and how usual treatment medications may change those outcomes. It may help researchers understand risks and benefits of common hypersomnia therapies.
Scottsdale, ArizonaAges 18–75 - NCT05254015Enrolling by invitation
Therapy for hoarding symptoms in adults 50+
This trial tests a combined therapy approach (cognitive rehabilitation plus exposure therapy) to reduce hoarding behaviors in older adults. You may benefit if your hoarding is your main diagnosis and your symptoms and medications are stable.
San Diego, CaliforniaAges 50 years+ - NCT04701177Enrolling by invitation
Smartphone-based study of brain biomarkers in memory clinic patients
This observational study follows people with (or at risk for) Alzheimer’s-related brain changes and a comparison group without them. It uses clinic visits, cognitive testing, questionnaires, and possibly a spinal fluid test to better understand brain biomarkers and how they relate to thinking and daily life.
Corfu, CorfuAges 45 years+ - NCT04240665Enrolling by invitation
Test a digital notebook for memory problems
This study tests a digital “memory notebook” to help people who have early memory concerns keep track and report changes over time. It may be useful if you’re having mild memory issues and can complete surveys with a study partner.
Sacramento, CaliforniaAges 60 years+ - NCT04165460Enrolling by invitation
CBT programs for anxiety and coping in cervical cancer
This study tests two structured talk-therapy programs (cognitive-behavioral therapy) to help people with cervical cancer manage anxiety, depression symptoms, and unhelpful coping skills. It also looks at the role of a main caregiver during care planning and support.
Mexico City, TlalpanAges 18 years+ - NCT04124029Recruiting
How head injuries affect brain health
This study looks at how mild or moderate head injuries (concussions) may relate to brain conditions like chronic traumatic encephalopathy (CTE) and Alzheimer's disease. By comparing people with and without head injuries, researchers hope to learn more about what causes brain changes over time.
Boston, MassachusettsAges 30–90 - NCT04262206RecruitingPhase 4
Testing how statins affect outcomes in adults 75 and older
This trial studies whether cholesterol-lowering medicine (a statin, specifically atorvastatin) improves health and benefits in people age 75 and older in everyday life. It may help doctors understand which older adults benefit most and how to use these medicines safely.
Birmingham, AlabamaAges 75 years+ - NCT06615973Recruiting
Stroke recovery and social factors study
This study looks at how social factors (like where you live or your income) might affect thinking and memory after a stroke. If you had a stroke before and joined a related study, you may be able to join this one.
Bethesda, MarylandAges 18–99 - NCT06761066Enrolling by invitation
Testing NVP-NK4146 for mild cognitive impairment due to Alzheimer's
This study tests a new medicine, NVP-NK4146, for people with mild cognitive impairment (MCI) due to Alzheimer's disease. The goal is to see if it can help slow down memory and thinking problems.
SeoulAges 60 years+ - NCT04495660Recruiting
Brain and hearing testing after cochlear implants in children
This study uses a non-painful brain-light monitor to check how hearing and thinking skills change after a cochlear implant in deaf children. It also compares results with children who have normal hearing.
ToulouseAges 10 months–7 years - NCT06254638Recruiting
Moveschool: Boosting physical activity during school
This trial tests a school-based program designed to increase physical activity levels during the school day for teenagers. It aims to see if adding more movement into the school routine can improve health and activity habits.
CáceresAges 11–16 - NCT07792876Recruiting
Testing ketone and carbohydrate supplements in trained cyclists
This study is testing how taking ketone and carbohydrate supplements affects performance in trained cyclists. It is looking for male amateur cyclists who train regularly and have a high fitness level.
Ribeirão Preto, São PauloAges 20–50 - NCT06004804Recruiting
Psychological treatments for chronic pain in veterans
This study compares two group psychological treatments for chronic pain delivered over video conference. It aims to see if these treatments help reduce pain and improve quality of life for veterans.
West Los Angeles, CaliforniaAges 60–95 - NCT07633470RecruitingPhase 4
Zunveyl for Alzheimer's disease symptoms and caregiver support
This study tests a medication called Zunveyl to see if it helps reduce behavioral and neuropsychiatric symptoms in people with mild-to-moderate Alzheimer's disease, and whether it reduces stress on family caregivers. You would need a confirmed Alzheimer's diagnosis supported by a blood test, and a dedicated caregiver who can attend visits and report on your symptoms.
Orange, CaliforniaAges 50 years+ - NCT05384158Recruiting
Testing a computer game for low mood, low pleasure, or anxiety
This trial looks at how a computer-based task performs when someone is dealing with depression-like symptoms, such as low mood, low interest/pleasure, or anxiety that affects daily functioning. You might find it helpful if you fit their symptom and safety requirements and are comfortable with computer tasks and (for some parts) MRI scanning.
Roanoke, VirginiaAges 25–50 - NCT07468279Recruiting
How brain stimulation affects memory
This study uses a non-invasive brain stimulation technique to explore how brain rhythms affect memory. You will attend sessions where you perform memory tasks while your brain activity is recorded via EEG. The goal is to understand and potentially improve memory functions.
Miami, FloridaAges 18–59 - NCT07789535Recruiting
Sleep study for people with high blood pressure and poor sleep
This study looks at how improving sleep might affect blood vessel health in people with high blood pressure who don't sleep well. You might join if you have high blood pressure and poor sleep quality.
Guimarães, Braga DistrictAges 18–70
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Common questions
- Are there clinical trials for cognitive?
- Yes. Clin2 currently lists 2,033 recruiting cognitive studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognitive trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognitive trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.