Clinical trials
Cognitive clinical trials
Below are recruiting cognitive clinical trials, each written for real people, not researchers. We’re tracking 2,033 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05435222Recruiting
Male-only therapy program for major depression
This study tests a counseling/psychotherapy program designed specifically for men with major depression. If you qualify, you may be offered this structured therapy and followed to see whether it helps depressive symptoms.
Zurich, Canton of ZurichAges 25–50 - NCT05456503RecruitingPhase 3
PET scan study of tau buildup in memory and brain disorders
This Phase 3 study uses a PET/CT scan to measure whether a brain protein called tau (and related disease patterns) builds up in different dementia conditions. The goal is to better match which disorders have which brain changes and how they progress.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05457725Recruiting
Study how aging affects learning to trust and distrust
This study looks at how thinking and learning processes change with age, especially around deciding what to trust. You may be asked to complete computer tasks and brief memory/thinking tests to understand these changes.
Gainesville, FloridaAges 18–100 - NCT05458323Recruiting
Vision testing and glasses change to improve thinking
This study checks whether better distance and near vision (through eye exams and correct glasses) can improve thinking and memory. You may be randomly assigned to receive eye care, and your ability to see and think will be measured.
Hyderabad, TelanganaAges 60 years+ - NCT05461092RecruitingEarly Phase 1
Nerve blocks to improve pain control after spinal fusion
This early-stage study tests whether a regional nerve block can improve pain control and recovery for older adults having elective lumbar spinal fusion. If you qualify, you may receive a special pain-control injection during surgery to reduce opioid needs and improve recovery comfort.
Iowa City, IowaAges 65 years+ - NCT05481749Recruiting
Neuropsychology testing for adults 80+ in Garraf
This study checks how older adults think and remember using a set of neuropsychological tests. It mainly looks at people age 80 and up living in the Garraf area who can travel to a study center.
Sant Pere de Ribes, BarcelonaAges 80 years+ - NCT05483166Recruiting
Parent coaching to support memory and behavior after childhood cancer
This pilot study tests a program that works with parents to support a child’s thinking, memory, and behavior after childhood cancer treatment. It may help by teaching parents strategies to support school and day-to-day functioning.
AarhusAges 10–17 - NCT05492032Recruiting
Brain stimulation sessions for teens with autism symptoms
This trial tests whether repeated, brain-based stimulation (done through the scalp) can improve symptoms in adolescents with autism spectrum disorder, and whether a later “booster” session adds more benefit. It may help learn which stimulation schedule works best, especially when teens also have attention symptoms—but not epilepsy or mood/anxiety disorders.
Hung Hom, KowloonAges 12–21 - NCT05491551Recruiting
Alcohol training program to help you cut back or quit
This study tests a structured training program for young adults who’ve been drinking heavily, to help them reduce drinking or quit. You’ll be asked to complete daily short check-ins and follow study instructions, and you may be randomly assigned to different parts of the program.
Berkeley, CaliforniaAges 18–26 - NCT05497024Recruiting
Decision aid testing for older men on prostate cancer surveillance
This trial tests an English decision aid (a patient guide) to help older men understand and feel comfortable with “active surveillance” for localized prostate cancer. It also checks how easy to use it is for patients, caregivers, and prostate cancer clinicians.
Houston, TexasAges 65 years+ - NCT05508841Recruiting
Study how brain stimulation may work in mild Alzheimer’s
This study looks at how mild to moderate Alzheimer’s affects response to a noninvasive brain stimulation treatment (transcranial direct current stimulation). It may help researchers learn who benefits most and why.
Toronto, OntarioAges 50–90 - NCT05510401Recruiting
Safe use study of an at-bed safety mattress system
This study checks whether a special bed-safety device (SÉCURIDRAP® SELFIA®) can be used safely for adults who get confused, move at night, or are at risk of falling out of bed. You may be able to join if you already have a prescription for the device and meet other safety and consent requirements.
BailleulAges 18 years+ - NCT05515224Recruiting
Study for adults 65+ with memory concerns
This study looks at ways to help older adults with new or ongoing memory or thinking concerns. You may be able to take part if you’re 65 or older, have cognitive concerns, can complete study visits in English or Spanish, and are able to see and hear well enough for assessments.
Bloomington, IndianaAges 65 years+ - NCT05525962Recruiting
Study factors that affect development in foster children
This study looks at how different stress and support factors may influence how children and teens grow and cope while they are involved with child protective services. It may help clinicians understand what supports work best for children in care.
CanteleuAges Up to 16 years - NCT05527093Recruiting
Brain-scan study mapping social thinking changes in epilepsy
This study uses special thinking and brain-scanning tests to understand how “social thinking” may change in people with certain types of epilepsy. You might benefit by having a detailed evaluation during your planned pre-surgery workup.
Gif-sur-YvetteAges 18–65 - NCT05528939Recruiting
Training attention skills for children after cancer
This trial tests a computer-based “attention-control training” program to see if it’s doable and helpful for children who finished treatment for acute lymphoblastic leukemia or a brain tumor. It also looks at how acceptable the program is for both kids and caregivers.
Washington D.C., District of ColumbiaAges 8–16 - NCT05531461Recruiting
Imaging study after clot removal with Tigertriever device
This study looks at brain images and thinking (cognition) after treatment to remove a large artery blood clot using the Tigertriever. It may help doctors understand how well the procedure works and how it affects long-term brain function.
Los Angeles, CaliforniaAges 18–75 - NCT05549102Recruiting
CBT therapy study for anxiety and brain circuit changes
This trial studies whether a specific form of talk therapy (CBT) changes brain activity in people with moderate anxiety. It may help your care team understand what works best and how brain “circuits” respond to treatment.
LondonAges 18–64 - NCT05556395Recruiting
Study after stroke to help thinking and memory recovery
This trial looks at stroke patients who can show specific scan findings on an MRI, then uses thinking tests by phone to track cognitive (thinking and memory) changes. It may help researchers understand whether targeting brain blood-flow disruption can improve post-stroke cognition.
Baltimore, MarylandAges 18 years+ - NCT05558709Recruiting
Test for thinking and behavior skills in neurodegenerative disease
This trial checks a new kind of paper-and-pen (or computer-based) test to better measure thinking and social/behavior skills in people with certain brain diseases. It may help researchers improve how these skills are tracked and understood over time.
ParisAges 18–90 - NCT05561205Recruiting
Brain stimulation to treat persistent apathy
This trial tests a noninvasive brain stimulation treatment (called rTMS) to help people who have had ongoing apathy (lack of motivation/interest) for at least a month. You might benefit if your apathy is persistent, your other symptoms are stable, and you meet the safety and medication rules.
Toronto, OntarioAges Any age - NCT05563805Recruiting
Virtual reality adventure training for movement and fitness
This study uses a virtual reality “adventure” game that gets you moving to train exercise skills and coordination. It’s designed for U.S. military veterans who can walk on their own and don’t have certain vision, balance, or medical limits.
Arlington, TexasAges 18–45 - NCT05573490Recruiting
Lifestyle program study for early-onset Alzheimer’s
This study tests a structured lifestyle intervention to help people with early-onset Alzheimer’s disease. It is designed for adults with confirmed Alzheimer’s-related brain changes, and may help with symptoms or day-to-day functioning.
Indianapolis, IndianaAges 40–75 - NCT05577585Recruiting
Ketamine treatment for obsessive-compulsive disorder symptoms
This study tests whether ketamine can reduce obsessive-compulsive disorder (OCD) symptoms and how it affects stress and thinking. It also compares ketamine to usual care to see if benefits and side effects differ.
Vienna, State of ViennaAges 18 years+
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Common questions
- Are there clinical trials for cognitive?
- Yes. Clin2 currently lists 2,033 recruiting cognitive studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognitive trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognitive trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.