Clinical trials
Colorectal Cancer (Diagnosis) clinical trials
Below are recruiting colorectal cancer (diagnosis) clinical trials, each written for real people, not researchers. We’re tracking 354 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07213570RecruitingPhase 2
Second-line regorafenib for advanced RAS-mutant colorectal cancer
This trial tests regorafenib as a second-line treatment for people with advanced colorectal cancer that has a RAS mutation. It aims to see if this targeted therapy can help when the first treatment stopped working.
Naples, ItalyAges 18 years+ - NCT06822413Recruiting
Using light and AI to find cancer early
This trial uses a special light-based test and artificial intelligence to detect several types of cancer early. It aims to see if this method can accurately identify cancer or precancerous changes before any treatment starts.
Nanchang, JiangxiAges Any age - NCT07166263RecruitingEarly Phase 1
Natural killer cell therapy for advanced stomach and colorectal cancer
This trial studies an experimental cell therapy called NK510 for people with advanced stomach or colorectal cancer that has not responded to standard treatments. The therapy uses natural killer cells, a type of immune cell, to attack the cancer. It may help slow or stop the cancer's growth.
Nanjing, JiangsuAges 18 years+ - NCT07162337Recruiting
Diet education to lower colon cancer risk after polyp removal
This study tests whether a diet education program can change the balance of gut bacteria and bile acids to lower the risk of colorectal cancer in people who have had polyps removed.
Boston, MassachusettsAges 18–80 - NCT07143487Recruiting
Family communication after genetic testing for colon cancer
This trial studies how patients with newly diagnosed colon cancer share genetic test results with their family members. It aims to improve communication and support after learning about hereditary risk.
Anchorage, AlaskaAges 18 years+ - NCT07125729Recruiting
Early cancer detection test for colorectal cancer
This trial uses two blood tests (Signatera and Haystack) to look for tiny bits of cancer DNA after surgery, to find out if the cancer comes back as early as possible. People with stage II, III, or IV colorectal cancer who have had or will have surgery to remove their tumor may join.
Goodyear, ArizonaAges 18 years+ - NCT07087561Recruiting
Nutrition and health education after colorectal cancer surgery
This trial tests whether a short-term nutritional supplement combined with health education can improve recovery after surgery for colorectal cancer. It is for people with stage IIa, IIb, or IIIa colon or rectal cancer who have completed surgery and are able to engage in follow-up.
Xi'an, ShaanxiAges 18 years+ - NCT07076823RecruitingPhase 1
Canagliflozin for MSI-H colorectal cancer
This trial tests a diabetes drug, canagliflozin, for people with a specific type of colorectal cancer (MSI-H). It's for those whose cancer has continued to grow after at least two standard treatments.
Chengdu, SichuanAges 18–80 - NCT07068529Recruiting
Metabolic biomarkers for early diagnosis and recurrence of colorectal cancer
This study looks at metabolic biomarkers in blood and tumor tissue to help detect colorectal cancer earlier, predict outcomes, and monitor for recurrence. It includes both people newly diagnosed with colorectal cancer and healthy volunteers for comparison.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07033026RecruitingPhase 2
Study of NGM120 for weight loss in colorectal cancer
This study tests an experimental drug called NGM120 for people with colorectal cancer who are losing weight (a condition called cancer cachexia). It is a placebo-controlled trial, meaning some participants will receive the drug and some will receive a placebo, to see if the drug helps stop or reverse this weight loss.
Los Angeles, CaliforniaAges 18 years+ - NCT07011576RecruitingPhase 2
Fruquintinib plus FOLFIRI for second-line metastatic colorectal cancer
This trial tests a combination of two drugs, fruquintinib and FOLFIRI chemotherapy, as a second treatment option for people with metastatic colorectal cancer. It is designed for patients who have already received one prior treatment containing oxaliplatin, fluoropyrimidine, and bevacizumab.
Denver, ColoradoAges 18 years+ - NCT05771181RecruitingPhase 2
Test vitamin E plus two cancer drugs for metastatic colon cancer
This trial tests whether adding vitamin E to two cancer medicines (fruityquintinib and tislelizumab) can work better in people with metastatic colorectal cancer that is mismatch-repair stable (MSS). It may help if your cancer has grown despite standard treatment, and you can meet the study’s safety and blood/organ requirements.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06934538RecruitingPhase 1/Phase 2
Immunotherapy trial for advanced colorectal cancer
This trial tests a new immunotherapy drug (STC-1010) for people with colorectal cancer that cannot be removed by surgery or has spread. It aims to see if the drug can shrink tumors or slow the disease.
Baltimore, MarylandAges 18–75 - NCT06936527Enrolling by invitationPhase 1/Phase 2
XS-03 plus chemotherapy and bevacizumab for metastatic colorectal cancer with RAS mutation
This trial tests an experimental drug called XS-03 combined with standard chemotherapy (FOLFOX or FOLFIRI) plus a targeted therapy (bevacizumab) for people with metastatic colorectal cancer that has a RAS mutation. The goal is to see if adding XS-03 helps shrink tumors or slows cancer growth better than current treatments.
BeijingAges 18–75 - NCT06919068Recruiting
Colon camera capsule for gut bacteria in the blood
This trial tests whether a camera capsule can detect problems in the large intestine when certain gut bacteria are found in the blood. If you have one of these bacteria and are stable enough for the exam, it might help identify the source of the infection.
OdenseAges 18 years+ - NCT06904677Recruiting
Urine test to predict colorectal cancer treatment response
This study uses a special urine test to see if it can predict how well colorectal cancer responds to treatment. If you are about to start treatment before surgery, you may be able to join by giving urine samples before and during therapy.
Beijing, Chaoyang DistrictAges 18–75 - NCT06889844Recruiting
Blood test for colorectal cancer cross-reactivity study
This research study uses a blood test to look for signs of colorectal cancer in people who have other types of cancer or digestive diseases. The goal is to see if the test can correctly tell the difference between colorectal cancer and other conditions.
Málaga, AndalusiaAges 18 years+ - NCT06889883Recruiting
Blood test for early colorectal cancer detection
This study is testing a new blood test to find colorectal cancer early. You may be able to join if you are about to have a colonoscopy or surgery for a suspected tumor.
Zaragoza, AragonAges 18 years+ - NCT06878131Recruiting
Precision-MRD: Targeted therapy study for colorectal cancer with MRD
This study looks at how well targeted therapies work for people with colorectal cancer who have minimal residual disease (MRD, tiny amounts of cancer left after treatment) detected by a blood test. It is for people who have a specific genetic change (biomarker) in their tumor and have not been treated with the targeted therapy for that biomarker before.
Houston, TexasAges 18 years+ - NCT06864338Recruiting
Pilot study for a new colorectal cancer screening test
This study tests a new stool-based test for detecting colorectal cancer and advanced polyps. It aims to see how well it works compared to a colonoscopy. The results may lead to a simpler screening option.
Morrisville, North CarolinaAges 18 years+ - NCT06868095Enrolling by invitation
Sarcopenia’s impact on early-onset colorectal cancer
This study looks at how muscle loss (sarcopenia) affects people diagnosed with colorectal cancer before age 50. It uses CT or MRI scans taken at diagnosis to measure muscle mass and see how it relates to treatment and outcomes.
Ages 18–49 - NCT06849362Enrolling by invitation
Optimizing immunotherapy for advanced colorectal cancer
This study looks at how well different combinations of immunotherapy drugs work for advanced colorectal cancer that is MSS or MSI-L or pMMR. It reviews past patient records to see which treatments help control the disease and slow its growth.
Changsha, HunanAges Any age - NCT06824064RecruitingPhase 2
RBS2418 for advanced metastatic colorectal cancer
This trial tests a new drug called RBS2418 for people with advanced colorectal cancer that has spread and is getting worse, even after other treatments have stopped working. The goal is to see if RBS2418 can help control the cancer.
Newark, DelawareAges 18 years+ - NCT06764680RecruitingPhase 2
Oral drugs and radiation for advanced colorectal cancer after standard therapy
This trial tests a combination of oral chemotherapy, targeted therapy, and immunotherapy, with or without radiation, for people with advanced colorectal cancer that hasn't responded to at least two prior treatments. The goal is to see if this approach can help shrink tumors or slow the disease.
Guangzhou, GuangdongAges 18 years+
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Common questions
- Are there clinical trials for colorectal cancer (diagnosis)?
- Yes. Clin2 currently lists 354 recruiting colorectal cancer (diagnosis) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a colorectal cancer (diagnosis) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a colorectal cancer (diagnosis) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.