Clinical trials
Colorectal (Colon or Rectal) Cancer clinical trials
Below are recruiting colorectal (colon or rectal) cancer clinical trials, each written for real people, not researchers. We’re tracking 867 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT01194648Recruiting
HIFU treatment for early prostate cancer
This trial studies a focused ultrasound treatment called HIFU for prostate cancer that appears limited to the early stages. It aims to treat cancer within the prostate while avoiding treatment spread to lymph nodes or distant organs.
London, EnglandAges Up to 90 years - NCT03919461RecruitingPhase 2
Preventing colon and rectal cancer spread after surgery
This Phase 2 study tests medicines given around the time of colon or rectal cancer surgery to help lower the chance the cancer will later spread to other parts of the body. If you are planned for curative (potentially curable) surgery and have no signs of spread yet, the trial may help prevent future metastases.
AfulaAges 20–80 - NCT04287088Recruiting
MRI plus shared decisions to help diagnose prostate cancer
This study looks at using a special prostate MRI (bpMRI) along with a risk-based shared decision process to guide diagnosis. It may help patients and clinicians decide on next steps using MRI results and individual risk.
JyväskyläAges 18 years+ - NCT05431530Recruiting
Quality of life after rectal surgery for advanced ovarian cancer
This trial studies how patients’ day-to-day quality of life changes after a specific type of rectal/low anterior resection during treatment for advanced ovarian cancer. It may help the medical team understand what symptoms and recovery needs to expect after surgery.
SeoulAges 18 years+ - NCT06266832RecruitingPhase 2
Short-course radiation with immunotherapy and chemo for rectal cancer
This trial tests a combination of short-course radiation, an immunotherapy drug (adebrelimab), and chemotherapy (CAPEOX) before surgery to help preserve the rectum in people with MSS/pMMR ultra-low rectal cancer. The goal is to shrink the tumor enough to avoid removing the rectum.
Hangzhou, ZhejiangAges 18 years+ - NCT06461793RecruitingPhase 2
Higher dose radiation with hormone therapy for high-risk prostate cancer
This trial tests a higher dose of radiation given in fewer sessions (hypofractionated) combined with hormone therapy for men with high-risk prostate cancer that has not spread. A gel spacer called SpaceOAR is used to protect the rectum. The goal is to see if this approach is safe and effective.
SeoulAges 20 years+ - NCT06461819RecruitingPhase 2
Higher radiation dose for low-to-intermediate prostate cancer
This trial tests if giving a higher dose of radiation in fewer sessions, while using SpaceOAR to protect the rectum, is safe for men with low-to-intermediate risk prostate cancer that hasn't spread.
SeoulAges 20 years+ - NCT06494696Recruiting
PSMA PET/MRI with MRI for prostate cancer risk
This study tests whether a special scan (PSMA PET/MRI) combined with a standard MRI can better detect prostate cancer. It is for men who have not had a biopsy yet and are suspected of having prostate cancer.
Taoyuan CityAges 40–85 - NCT07757490Recruiting
Sonablate HIFU registry for prostate cancer and BPH
This study is a registry that collects information from men who have had Sonablate HIFU treatment for prostate cancer or enlarged prostate (BPH). It will help doctors learn more about how well this treatment works in real life.
Indianapolis, IndianaAges 18 years+ - NCT07660276Enrolling by invitation
AI predicts prostate cancer spread from biopsy
This study uses an artificial intelligence (AI) system to look at prostate biopsy samples and predict if the cancer has spread to the lymph nodes. It may help doctors decide on the best treatment without needing extra surgery or scans.
Changsha, HunanAges 18–90 - NCT07644598RecruitingPhase 2
Targeted Radiation Therapy for Low to Intermediate Risk Prostate Cancer
This study tests a new radiation treatment approach that uses MRI imaging to target specific tumor areas within the prostate while reducing radiation to healthy tissue. It may help patients with early-stage prostate cancer get effective treatment with fewer side effects.
Washington D.C., District of ColumbiaAges 18 years+ - NCT07607873Recruiting
Transplant vs surgery after chemo for liver-only colorectal cancer
This trial compares liver transplant versus liver surgery for people whose colorectal cancer has spread only to the liver and cannot be removed initially. You would first receive chemotherapy to shrink the tumors, and if they become removable, you may be randomly assigned to have a liver transplant or standard liver surgery.
MilanAges 18 years+ - NCT07543757Recruiting
Blood test to help decide if a prostate biopsy is needed
This study tests a new blood test (Proclarix) that may help doctors decide if a prostate biopsy is needed. It is for men with a slightly elevated PSA who are already considering a biopsy.
San Diego, CaliforniaAges 40–75 - NCT07541911Recruiting
Confocal Microscopy to Check Prostate Cancer Surgery Margins
This study tests whether a special microscope can help surgeons see cancer margins (edges) during prostate removal surgery to make sure all cancer is removed. It may help surgeons make real-time decisions about how much tissue to remove.
LondonAges 18 years+ - NCT07492927Recruiting
Liquid biopsy for prostate cancer diagnosis
This study uses a blood test to detect prostate cancer more accurately than traditional methods. It looks for genetic material from cancer cells to help decide if a prostate biopsy is needed.
Chicago, IllinoisAges 18 years+ - NCT07454603Recruiting
Blood test for prostate cancer risk
This trial tests a new blood test to help decide if you need a prostate biopsy. It may help men with high PSA levels or an abnormal rectal exam avoid unnecessary procedures.
Branford, ConnecticutAges 45–80 - NCT07460843Recruiting
Comparing two types of prostate biopsy for diagnosis
This study compares two methods of taking prostate biopsy samples (TB+PB vs TB+6SB) to see which is better at diagnosing prostate cancer. It is for men who have a suspicious spot on their MRI and meet certain PSA or exam criteria.
Beijing, Beijing MunicipalityAges 18–85 - NCT06468332Recruiting
AI learning from MRI and tissue to improve prostate cancer care
This study uses artificial intelligence to look at your MRI scans, tissue samples, and medical records to learn more about prostate cancer and find better ways to treat it. You may join if you've had prostate removal surgery or have advanced prostate cancer.
NovaraAges 18–80 - NCT07425054RecruitingPhase 2
Chemoradiation with or without immunotherapy for anal cancer
This trial tests whether adding an immunotherapy drug (retifanlimab) to standard chemoradiation improves outcomes for people with locally advanced anal cancer. The treatment is adjusted based on HPV DNA levels in your blood.
Cleveland, OhioAges 18 years+ - NCT07339904Recruiting
Bowel Function After Rectal Cancer Surgery
This study follows people with rectal cancer who have surgery to remove part of the rectum. It looks at how bowel function changes over time, and whether different treatments before surgery affect recovery.
Edegem, AntwerpAges 18 years+ - NCT07292818RecruitingPhase 1
Hyaluronic acid gel spacer study for cervical cancer radiation
This trial tests if a gel spacer made from hyaluronic acid can protect healthy tissue during radiation for cervical cancer. It may help reduce side effects for patients getting chemoradiotherapy with brachytherapy.
Chapel Hill, North CarolinaAges 18 years+ - NCT06420115Recruiting
Comparing needle sizes for prostate MRI-targeted biopsy
This study compares two different needle sizes used during a prostate biopsy to see which one finds cancer more accurately and causes fewer side effects. It is for people who have not been diagnosed with prostate cancer before and have a suspicious MRI finding.
Padua, ItalyAges 18 years+ - NCT04008407Recruiting
Monitoring outcomes after removing certain colon growths
This study follows patients who are having surgery to remove a specific type of flat colon growth. It aims to see how safe and effective a “selective” approach is, based on what the growth looks like and your situation.
Westmead, New South WalesAges 18 years+ - NCT05935124Recruiting
White light or narrow-band imaging for colon polyp detection
This trial compares two camera light styles during screening colonoscopy to see which one better finds polyps on the right side of the colon. If you’re having a routine screening and have no concerning symptoms, the results may help improve how doctors spot polyps early.
Sydney, New South WalesAges 18 years+
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Common questions
- Are there clinical trials for colorectal (colon or rectal) cancer?
- Yes. Clin2 currently lists 867 recruiting colorectal (colon or rectal) cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a colorectal (colon or rectal) cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a colorectal (colon or rectal) cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.