Clinical trials
Colorectal (Colon or Rectal) Cancer clinical trials
Below are recruiting colorectal (colon or rectal) cancer clinical trials, each written for real people, not researchers. We’re tracking 893 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07385521Recruiting
AI to predict cancer return after liver surgery
This trial uses artificial intelligence to predict whether colorectal cancer that spread to the liver will come back after surgery. It may help doctors better understand your risk and plan follow-up care.
MilanAges 18 years+ - NCT07660276Enrolling by invitation
AI predicts prostate cancer spread from biopsy
This study uses an artificial intelligence (AI) system to look at prostate biopsy samples and predict if the cancer has spread to the lymph nodes. It may help doctors decide on the best treatment without needing extra surgery or scans.
Changsha, HunanAges 18–90 - NCT06835725RecruitingPhase 2
Comparing two prostate radiation schedules for intermediate risk
This trial compares giving radiation in 2 treatments versus 5 treatments for prostate cancer that hasn't spread. It's for men with low or intermediate risk prostate cancer who are healthy enough to undergo a short course of targeted radiation.
Surrey, British ColumbiaAges 18 years+ - NCT07607873Recruiting
Transplant vs surgery after chemo for liver-only colorectal cancer
This trial compares liver transplant versus liver surgery for people whose colorectal cancer has spread only to the liver and cannot be removed initially. You would first receive chemotherapy to shrink the tumors, and if they become removable, you may be randomly assigned to have a liver transplant or standard liver surgery.
MilanAges 18 years+ - NCT06100055Recruiting
Small vs large volume rectal irrigation for constipation
This study compares two different ways of using a water-based treatment (rectal irrigation) to help people with long-term constipation caused by trouble emptying the bowels. It looks at whether using more or less water works better.
LondonAges 18 years+ - NCT07644598RecruitingPhase 2
Targeted Radiation Therapy for Low to Intermediate Risk Prostate Cancer
This study tests a new radiation treatment approach that uses MRI imaging to target specific tumor areas within the prostate while reducing radiation to healthy tissue. It may help patients with early-stage prostate cancer get effective treatment with fewer side effects.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06840977Recruiting
Low dose chemo for older adults with colorectal cancer
This trial tests a lower-dose chemotherapy regimen for adults aged 70 or older with metastatic colorectal cancer that has not been treated yet. It aims to see if a gentler approach can still be effective and easier to tolerate.
Genova, GEAges 70–99 - NCT03819751Recruiting
MRI-guided prostate biopsy: software vs visual matching
This study compares two ways of using prostate MRI images to guide a biopsy and check how accurately prostate cancer can be found. If you have MRI spots that may be cancer, the trial will help test whether computer software or a visual method works better.
Leuven, Vlaams-brabantAges 50–75 - NCT03919461RecruitingPhase 2
Preventing colon and rectal cancer spread after surgery
This Phase 2 study tests medicines given around the time of colon or rectal cancer surgery to help lower the chance the cancer will later spread to other parts of the body. If you are planned for curative (potentially curable) surgery and have no signs of spread yet, the trial may help prevent future metastases.
AfulaAges 20–80 - NCT04008407Recruiting
Monitoring outcomes after removing certain colon growths
This study follows patients who are having surgery to remove a specific type of flat colon growth. It aims to see how safe and effective a “selective” approach is, based on what the growth looks like and your situation.
Westmead, New South WalesAges 18 years+ - NCT04249154RecruitingPhase 2
After prostate surgery, test radiation plus hormone shots
This trial studies whether giving a shorter-course radiation plan after prostate surgery, along with hormone shots (LHRH), can improve outcomes for people with higher-risk prostate cancer. You may be eligible if your PSA (a blood marker) is either still low but high-risk by pathology, or it has started to rise again after surgery.
Montreal, QuebecAges 18 years+ - NCT04287088Recruiting
MRI plus shared decisions to help diagnose prostate cancer
This study looks at using a special prostate MRI (bpMRI) along with a risk-based shared decision process to guide diagnosis. It may help patients and clinicians decide on next steps using MRI results and individual risk.
JyväskyläAges 18 years+ - NCT04556916Recruiting
Early prostate cancer screening with MRI before biopsy
This study is testing an approach to find prostate cancer earlier in men who may be at higher risk. If you fit the criteria, you may get an mpMRI scan before undergoing a prostate biopsy to check for cancer.
MontpellierAges 40 years+ - NCT04593407Recruiting
Check the best method to remove large flat colon polyps
This study compares two endoscopy techniques to remove large, flat-looking colon polyps. It aims to see which method removes the polyp more completely and safely.
MadridAges 18–85 - NCT04732156Recruiting
Test AI and MRI scores to spot prostate cancer
This study compares how well a doctor’s MRI reading (the PI-RADS score) and a computer AI tool detect prostate cancer. It may help improve how men get targeted biopsies and avoid missing important cancers.
BordeauxAges 18–80 - NCT05043012Recruiting
Testing a special MRI scan for prostate cancer diagnosis
This study checks how well a new prostate MRI scan (using a flexible coil and multiple MRI types) can correctly identify prostate cancer and help with treatment planning. You may be able to help doctors improve prostate imaging before you have surgery.
Houston, TexasAges 18 years+ - NCT05393609Recruiting
Quality-of-life study during surgery for diverticular disease
This trial studies how people’s quality of life changes around diverticular disease surgery. It may help doctors understand what to expect and how to better support patients before and after surgery.
Randers, Central JutlandAges 18 years+ - NCT05431530Recruiting
Quality of life after rectal surgery for advanced ovarian cancer
This trial studies how patients’ day-to-day quality of life changes after a specific type of rectal/low anterior resection during treatment for advanced ovarian cancer. It may help the medical team understand what symptoms and recovery needs to expect after surgery.
SeoulAges 18 years+ - NCT05574647Recruiting
Fast prostate MRI and guided biopsy testing for prostate cancer
This study checks whether a faster prostate MRI and image-matching (image-fusion) can better find suspicious spots so doctors can target a biopsy. If you have concerning prostate exam results or PSA blood test results, you may get an MRI and, if something looks suspicious, a biopsy using MRI images.
Southend-on-Sea, EssexAges 18 years+ - NCT05648253Recruiting
Hyivy device after pelvic radiation for vaginal health
This study checks whether a special vaginal device (Hyivy) is safe and workable after pelvic radiation for certain cancers. You may be asked to use it for 12 weeks to help with vaginal changes after treatment, and you would visit the study team regularly.
Kitchener, OntarioAges 18 years+ - NCT05697562Recruiting
Embolization treatment for hemorrhoid bleeding
This trial studies a procedure that blocks blood flow to bleeding hemorrhoids (called superior rectal arterial embolization). It may help people with hemorrhoid bleeding who are being considered for treatment, especially when bleeding is significant.
JetteAges 18 years+ - NCT05714774Recruiting
Ultrasound analysis methods during HIFU prostate cancer treatment
This study compares different ways to analyze ultrasound images in real time while treating localized prostate cancer with HIFU (a focused ultrasound treatment). It aims to improve how safely and accurately the treatment is monitored.
LyonAges 50 years+ - NCT05754580Recruiting
Boost radiation for intermediate or higher-risk prostate cancer
This study tests a stronger, focused radiation plan for intermediate to higher-risk prostate cancer. It combines a high-dose internal radiation “boost” with external radiation to try to improve cancer control while keeping side effects manageable.
Omaha, NebraskaAges 19 years+ - NCT05835206RecruitingPhase 2
Drug to reduce antibiotic-resistant gut bacteria
This Phase 2 study tests whether an investigational treatment can help clear or reduce antibiotic-resistant bacteria living in the gut. It may help prevent these germs from causing future infections by targeting specific resistant bacteria found on stool or rectal swabs.
Atlanta, GeorgiaAges 18 years+
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Common questions
- Are there clinical trials for colorectal (colon or rectal) cancer?
- Yes. Clin2 currently lists 893 recruiting colorectal (colon or rectal) cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a colorectal (colon or rectal) cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a colorectal (colon or rectal) cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.