Clinical trials
Colorectal clinical trials
Below are recruiting colorectal clinical trials, each written for real people, not researchers. We’re tracking 1,199 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04359069Recruiting
Shorter urinary catheter time after pelvic surgery
This study looks at whether the urinary (Foley) catheter can stay in place for a shorter time after certain pelvic operations. It aims to see if timing of catheter removal is safer and more comfortable, especially for bladder function.
Los Angeles, CaliforniaAges 18 years+ - NCT04367987Recruiting
Heart Rate Changes After Colorectal Surgery
This study measures how your heart rate varies after planned colorectal surgery to see if these changes can predict complications. Researchers will monitor your heart rhythm before and after your operation to understand whether certain patterns might warn of problems early.
NîmesAges 18 years+ - NCT04364373Recruiting
Test of different lymph node surgery for left colon cancer
This study compares two types of lymph node removal during surgery for left-sided colon cancer. It aims to see which surgical approach may work better while ensuring you can still safely complete chemotherapy.
MoscowAges 18–75 - NCT02584244RecruitingPhase 1/Phase 2
Testing an imaging scan to find gastrointestinal cancer
This study checks how well the LUM Imaging System can detect cancers of the esophagus, colon, or pancreas during the time you are preparing for surgery. It’s mainly meant to see if the scan works safely and clearly for doctors to find cancer areas.
Boston, MassachusettsAges 18 years+ - NCT04222413RecruitingPhase 1
Study of metarrestin for advanced solid tumors
This study tests an experimental drug called metarrestin for people with solid tumors that have spread or come back after standard treatment. It may help by targeting a protein involved in cancer cell growth.
Fairway, KansasAges 12–120 - NCT04144907Recruiting
Protein needs study for colorectal or breast cancer
This study tests how much protein people with colorectal or breast cancer need during treatment or recovery. It may help improve nutrition guidance and support for maintaining health during chemo or after surgery.
Edmonton, AlbertaAges 45–80 - NCT03539822RecruitingPhase 1/Phase 2
Cabozantinib and immunotherapy for advanced stomach or bowel cancers
This early-phase study tests a combination of anti-cancer pills and immune-based treatment for people with advanced stomach, esophagus, colorectal, or liver cancer. It aims to shrink tumors and see how safe the treatment is, including whether biopsy testing can help guide future care.
Westwood, KansasAges 18 years+ - NCT03947385RecruitingPhase 1/Phase 2
First drug test for metastatic uveal melanoma with specific gene changes
This Phase 1/2 trial studies IDE196 in adults with metastatic uveal melanoma that has certain gene mutations or fusions. It’s mainly testing safety and correct dosing, and may help shrink tumors in patients matched to the tumor’s genetic changes.
Los Angeles, CaliforniaAges 18 years+ - NCT03837782Enrolling by invitation
Surgery outcomes for early to mid-stage colon cancer
This study looks at how well surgery works for people with colorectal cancer that has not spread to distant organs. It mainly includes patients who can have the tumor completely removed and accurately staged using lymph node samples.
Tianjin, Tianjin MunicipalityAges 18–90 - NCT03740256RecruitingPhase 1
HER2-targeted oncolytic virus plus custom immune cells for solid cancers
This Phase 1 study tests a treatment plan that combines a virus designed to attack cancer with your own custom immune cells that target HER2. It aims to shrink advanced HER2-positive solid tumors (and make future options safer/more effective).
Houston, TexasAges 18 years+ - NCT03862781Recruiting
Quicker bowel recovery after minimally invasive right colon surgery
This study looks at whether a specific internal stitch connection (an anastomosis) helps your bowel start working sooner and may help you leave the hospital earlier after right colon surgery. It’s mainly for adults having planned, minimally invasive right hemicolectomy.
Grand Rapids, MichiganAges 18 years+ - NCT03748485Recruiting
Chemo after surgery for certain stage III colon cancer
This trial studies whether adding chemotherapy after surgery helps people with colon cancer that was diagnosed before surgery as stage III and later found to be without certain high-risk features. It may help lower the chance the cancer comes back, but you must meet specific surgery and health criteria.
Guangzhou, GuangdongAges 18–75 - NCT03715933RecruitingPhase 1
Test drug INBRX-109 for advanced or metastatic solid tumors
This Phase 1 trial tests INBRX-109, a cancer-targeting drug, in people whose solid cancers are locally advanced or spread to other parts of the body. Because it’s Phase 1, the main goal is to see whether it’s safe and how well it can work for different tumor types that meet specific requirements.
Scottsdale, ArizonaAges 12–85 - NCT03526835RecruitingPhase 1/Phase 2
Study of MCLA-158 for advanced solid tumors
This trial tests a new experimental drug called MCLA-158 (petosemtamab) for people with advanced solid tumors, especially head and neck cancer or colorectal cancer, that have not responded to standard treatments. The study aims to see if this drug can shrink tumors or slow their growth.
La Jolla, CaliforniaAges 18 years+ - NCT03551951Recruiting
Testing cancer cells and DNA in blood, urine, and bone marrow
This study looks for cancer-related cells and DNA in samples like blood, urine, and (for some) bone marrow. The goal is to see whether these tests can help detect or track solid cancers with minimal added procedures.
Columbia, MissouriAges 18 years+ - NCT03303495RecruitingPhase 3
Second-line chemo with or without bevacizumab for colon cancer
This Phase 3 study compares two treatment plans for people with metastatic colorectal cancer that got worse or caused side effects after first chemotherapy. It looks at whether adding bevacizumab (a medicine that targets blood vessels feeding tumors) improves outcomes versus using a different chemotherapy approach.
Guangzhou, GuangdongAges 18 years+ - NCT02838836Recruiting
Checking for cancer DNA and tumor cells in bodily samples
This study looks for cancer-related material in blood, urine, and sometimes bone marrow. It may help researchers understand how to detect cancer activity and track it over time using less invasive tests.
Columbia, MissouriAges 18 years+ - NCT02948972Recruiting
Surgery for bowel endometriosis to improve fertility
This trial studies whether fully removing deep endometriosis from the bowel (“bowel endometriosis surgery”) can improve fertility in people trying to get pregnant through IVF. It focuses on those with infertility and ongoing pain despite usual medicines.
Clermont-FerrandAges 18–38 - NCT02906943Recruiting
Testing cancer tissue to guide targeted treatment choices
This trial studies advanced solid tumors by using stored tumor samples to look for molecular clues. The goal is to help doctors better choose cancer treatments that may work for your specific tumor.
Hamilton, OntarioAges 18 years+ - NCT01915225Recruiting
Collecting solid tumor samples during cancer biopsy or surgery
This trial collects tissue (samples) from people who are already scheduled for biopsy or surgery for certain solid cancers. It aims to improve future testing and research while checking that taking the sample is safe and doesn’t add extra risk.
Bethesda, MarylandAges 2 years+ - NCT00843375Recruiting
Testing stool samples to find early colon cancer and polyps
This study checks stool samples to see how well stool tests can detect early colon cancer and precancerous growths called adenomas. If you qualify, you’ll collect stool samples for a lab test (FIT) and sometimes this helps sort who should get follow-up testing.
Los Angeles, CaliforniaAges 18 years+ - NCT01174121RecruitingPhase 2
Immunotherapy made from your tumor-fighting immune cells
This trial tests a treatment made from your own immune cells (called tumor-infiltrating lymphocytes, or TILs) for certain metastatic cancers. It’s designed for people whose cancer has not responded to standard treatments and who can safely provide a small tumor sample for cell-making.
Bethesda, MarylandAges 18–72 - NCT00001823Recruiting
Surgery Branch Screening for Cancer Treatment Studies
This is a screening evaluation to see if you might be eligible for cancer treatment research studies at the National Cancer Institute's Surgery Branch. Doctors will review your medical history, imaging, and test results to determine which clinical trials might be right for you.
Bethesda, MarylandAges 18 years+
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Common questions
- Are there clinical trials for colorectal?
- Yes. Clin2 currently lists 1,199 recruiting colorectal studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a colorectal trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a colorectal trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.