Clinical trials
Combination Therapy clinical trials
Below are recruiting combination therapy clinical trials, each written for real people, not researchers. We’re tracking 888 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06252571RecruitingPhase 2
Melatonin and light therapy for idiopathic hypersomnia
This trial tests whether taking melatonin at night and using a bright light therapy device in the morning can improve excessive daytime sleepiness in people with idiopathic hypersomnia. It is a double-blind study, meaning neither you nor the doctors will know if you are getting the real treatment or a placebo.
StrasbourgAges 18–40 - NCT05029531RecruitingPhase 3
Immuno-chemotherapy for infants with B-lineage ALL
This trial tests a combination of medicines (immunotherapy plus chemotherapy) in babies diagnosed with a type of leukemia called B-lineage acute lymphoblastic leukemia (ALL). It aims to improve how well treatment works and is delivered safely in very young children.
Moscow, Samory-Mashela,1Ages 1 day–12 months - NCT06764797RecruitingPhase 3
Virtual reality and brain stimulation for arm recovery after stroke
This trial tests whether combining virtual reality mirror therapy with a gentle brain stimulation technique can improve arm and hand movement in people who have had a stroke. It may be an option if you have moderate to severe arm weakness and it has been more than three months since your stroke.
Riyadh, Riyadh RegionAges 18 years+ - NCT07450599RecruitingPhase 2
Darolutamide plus hormone therapy before prostate cancer surgery
This trial tests a medicine called darolutamide taken with hormone therapy (ADT) before surgery to remove the prostate. It is for men with a high-risk prostate cancer that has not spread to other parts of the body.
Hefei, AnhuiAges 18 years+ - NCT06998407RecruitingPhase 1/Phase 2
Study of AVZO-023 for advanced solid tumors
This trial tests a new drug, AVZO-023, alone or with other treatments, for people with advanced solid tumors that have not responded to standard therapy. The goal is to see if it can shrink tumors or slow their growth.
Los Angeles, CaliforniaAges 18 years+ - NCT07223814RecruitingPhase 3
Testing a new drug with standard chemo for AML
This trial adds an experimental drug called bleximenib to the usual chemotherapy for people newly diagnosed with AML who have certain genetic changes (NPM1 or KMT2A). The goal is to see if adding this drug helps the treatment work better.
San Francisco, CaliforniaAges 18 years+ - NCT06913257Recruiting
Shockwave therapy plus rehab vs rehab alone for burn scars
This study compares adding shockwave therapy to standard rehabilitation for treating painful, itchy burn scars that are at least 6 months old. It aims to see if the combination is more cost-effective than rehab alone.
CairoAges 18–65 - NCT05782270RecruitingPhase 4
Blood thinner medicines after bypass surgery with artery unblocking
This trial studies which blood-thinning medicine combination is safest and most helpful after coronary bypass surgery combined with a procedure to unblock the artery (endarterectomy). It focuses on preventing dangerous blood clots while also avoiding excess bleeding.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06208410RecruitingPhase 1/Phase 2
JS105 plus other treatments for advanced solid tumors
This trial tests a new drug called JS105 combined with other anti-cancer therapies for people with certain advanced breast, ovarian, endometrial, or cervical cancers. It aims to find out if these combinations are safe and effective.
Zhengzhou, HenanAges 18–75 - NCT06035679Recruiting
Combination therapy before surgery for HER2-positive breast cancer
This trial tests a combination of targeted therapies and chemotherapy given before surgery for HER2-positive breast cancer. It aims to see if this approach helps shrink tumors and improve outcomes.
Fuzhou, FujianAges 18–75 - NCT06475196Enrolling by invitation
Immunotherapy plus chemo before surgery for esophageal cancer
This trial tests a combination of immunotherapy (sintilimab) and chemotherapy given before surgery for esophageal cancer that can be surgically removed. The goal is to see if this approach helps shrink tumors and improve outcomes.
Xi'an, ShaanxiAges 18–75 - NCT06719362RecruitingPhase 1
Testing a new cancer drug alone and with other therapies
This trial tests an experimental drug called M3T01, either alone or combined with pembrolizumab and other standard treatments, for people with advanced solid tumors or glioblastoma. The goal is to see if it is safe and effective.
Portland, OregonAges 18 years+ - NCT07353684RecruitingPhase 2
Adebrelimab plus apatinib with chemo for gastric cancer
This trial tests a combination of two targeted drugs (adebrelimab and apatinib) with standard chemotherapy (SOX regimen) before surgery for gastric cancer that cannot be removed right away. The goal is to shrink the tumor enough to make surgery possible.
Beijing, Beijing MunicipalityAges 18–75 - NCT07054931RecruitingPhase 2
Combination HIV vaccine and antibody therapy study
This trial tests a combination of an HIV vaccine and a new antibody treatment (GS-2872) to see if it can help control HIV without daily pills. It is for people with well-controlled HIV who are looking for ways to reduce their dependence on antiretroviral therapy.
LondonAges 18–64 - NCT06474455RecruitingPhase 1/Phase 2
Study of SHR-9839 with other treatments for advanced solid tumors
This trial tests a new drug called SHR-9839 combined with other cancer treatments for people with advanced solid tumors, including a certain type of lung cancer. The goal is to see if the combination is safe and effective against the cancer.
Zhengzhou, HenanAges 18–75 - NCT07190677Recruiting
Nivolumab plus ipilimumab with chemo for advanced lung cancer
This trial tests combining two immunotherapy drugs (nivolumab and ipilimumab) with chemotherapy as a first treatment for advanced lung cancer that has spread or come back. It may help if your cancer hasn't been treated before and doesn't have certain genetic changes.
Pavia, LombardyAges Any age - NCT07385313RecruitingPhase 4
Sheep Tissue and Vacuum Therapy for Deep Wound Healing
This trial tests a combination of a special sheep-derived material (OFM) and a vacuum dressing to help rebuild deep wounds with exposed bone or tendon. It aims to speed up healing in arm or leg injuries.
Aurora, ColoradoAges 18 years+ - NCT05934331RecruitingPhase 2
Study for CLDN18.2-positive advanced gut cancers after first treatment
This Phase 2 trial tests a combination anti-cancer medicine (LM-302) plus other anti-tumor treatments for advanced gastrointestinal cancers. It’s designed for people whose tumors test positive for CLDN18.2 and who have already tried standard first-line treatment but didn’t respond or couldn’t tolerate it.
ShanghaiAges 18–80 - NCT07198633RecruitingPhase 1/Phase 2
Study of new drugs for advanced prostate cancer
This trial tests two new drugs (QLC5508 and QLH12016) alone or together with other treatments for prostate cancer that has spread to other parts of the body. It may be an option if standard treatments have stopped working or caused side effects.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT07050056RecruitingPhase 2
Immunotherapy plus radiation before lung cancer surgery
This study tests whether giving a combination of the immunotherapy drug tislelizumab and chest radiation before surgery can improve outcomes for people with early-stage, operable lung cancer. The goal is to find out if this approach helps shrink the tumor and makes surgery more effective.
Yangzhou, JiangsuAges 18–70 - NCT06685289RecruitingPhase 2
Donafenib and capecitabine after surgery for biliary cancer with high risk of return
This trial tests whether taking donafenib and capecitabine pills after surgery can help prevent biliary cancer from coming back in people who have a high risk of recurrence. It is for patients whose cancer was completely removed but had certain features that make recurrence more likely.
Nanjing, JiangsuAges 18–75 - NCT06466642Recruiting
Brain training for memory and thinking with HIV
This study tests if two types of computer-based brain exercises can help improve memory, thinking, and daily function in people living with HIV who have mild mental slowdowns. Participants will do about 10 hours of one brain game and 10 sessions of another over 5 weeks.
Cape Town, Western CapeAges 30–50 - NCT07140393RecruitingPhase 1/Phase 2
Combination therapy for advanced solid tumors
This study tests a new drug called HRS-4508 combined with other cancer treatments for people with advanced solid tumors that cannot be removed by surgery or have spread. The goal is to see if the combination is safe and effective.
Beijing, Beijing MunicipalityAges 18–75 - NCT03249519Recruiting
Radiation plus heat for advanced cervical cancer
This trial studies whether adding controlled heat (“hyperthermia”) to radiation therapy (or radiation with chemotherapy) can improve outcomes in advanced cervical cancer. It focuses on people who can safely receive intensive pelvic radiation and heat treatment.
ErlangenAges 18 years+
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Common questions
- Are there clinical trials for combination therapy?
- Yes. Clin2 currently lists 888 recruiting combination therapy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a combination therapy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a combination therapy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.