Clinical trials
Congenital Heart Disease in Children clinical trials
Below are recruiting congenital heart disease in children clinical trials, each written for real people, not researchers. We’re tracking 84 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT01192048Recruiting
Study genetics in congenital heart disease
This study looks at how genes may contribute to congenital heart disease. It may help researchers better understand causes and risk in families like yours.
Columbus, OhioAges Any age - NCT07059689Recruiting
Comparing breathing support after heart surgery in children
This trial compares two types of breathing support (high-flow nasal cannula vs. non-invasive ventilation) in children who have recently had heart surgery and are at high risk of having trouble breathing after their breathing tube is removed. The goal is to see which method works better to help them breathe on their own.
Jakarta, DKI JakartaAges Up to 18 years - NCT05386173Recruiting
Tests fetal aortic valve balloon surgery for severe narrowing
This trial studies whether doing a procedure before birth to open a baby’s aortic valve improves outcomes. It compares this approach in a specific group of pregnancies with severe heart flow problems seen on ultrasound.
San Francisco, CaliforniaAges 5 months–7 months - NCT06075251Recruiting
Online support for parents of kids with heart conditions
This study provides an online support program for parents or caregivers of children (ages 3 to 9) who have a congenital heart condition (a heart problem present at birth). The goal is to help you and your child cope and thrive, and you can join from home if you live in Ontario.
Toronto, OntarioAges 3–9 - NCT07608432RecruitingPhase 3
Testing a New DMD Treatment Given Every 4 Weeks
This study tests whether a new medicine called zeleciment rostudirsen can help ambulatory (walking) males with Duchenne muscular dystrophy (DMD). The medicine is given as an intravenous infusion (through a vein) every 4 weeks and works by helping the body produce a protective muscle protein.
Hillsborough, North CarolinaAges 4–18 - NCT06840717Recruiting
Genetic links to type 2 asthma in kids
This study looks at how certain genes might be connected to type 2 asthma in children. It aims to find out which kids are more likely to have asthma so doctors can better treat it.
Guangzhou, GuangdongAges 3–14 - NCT00327860Recruiting
Kidney disease in children study that follows patients over time
This is a long-term study that watches children and young adults with chronic kidney disease to understand how the illness changes and to improve care. You may be asked to complete regular visits and questionnaires, and your kidney function will be tracked over time.
Kansas City, MissouriAges 6 months–22 years - NCT06175104Recruiting
HeartGPS: Support for parents after a prenatal heart diagnosis
This study tests a counseling program for parents whose unborn baby has a serious heart condition called single ventricle. The program aims to help parents manage stress and support their baby's development before and after birth.
Los Angeles, CaliforniaAges 18 years+ - NCT07019857Recruiting
Thymus removal and immunity in infant heart surgery
This study looks at how removing the thymus gland during infant heart surgery affects the immune system. It compares babies who have their thymus removed with those who have heart surgery without removing it, and with babies having other types of surgery.
NantesAges Up to 6 months - NCT07226219RecruitingPhase 1
Medication to help attention in children with sickle cell disease
This study tests whether a common medication called methylphenidate (often used for ADHD) can help children with sickle cell disease who have attention or memory problems. If the child qualifies, the study may offer a new way to improve focus and daily functioning.
Memphis, TennesseeAges 8–17 - NCT07188805RecruitingPhase 3
Finerenone for children with heart failure
This study tests a medicine called finerenone in children with heart failure. It looks at whether finerenone helps the heart work better and is safe compared to a placebo (a dummy pill), when taken with the usual heart-failure medicines.
Aurora, ColoradoAges 6 months–17 years - NCT06819683RecruitingPhase 1
Testing a new oxygen sensor in people with and without mitochondrial myopathy
This study tests a tiny sensor that measures oxygen levels in muscle. It will help researchers understand how oxygen is used during exercise. If you have mitochondrial myopathy or are a healthy volunteer, you might be able to join.
Philadelphia, PennsylvaniaAges 18–65 - NCT04086329RecruitingPhase 1
Testing an oxygen sensor during exercise in muscle disease
This early (Phase 1) study checks whether a tiny oxygen-sensing device works reliably while people with mitochondrial muscle disease (and some healthy volunteers) ride a stationary bike. The goal is to see if the sensor can measure oxygen use during exercise and help future monitoring or research.
Philadelphia, PennsylvaniaAges 18–65 - NCT07799831Recruiting
Oral health and saliva bacteria in children with juvenile idiopathic arthritis
This study looks at how oral health and mouth bacteria relate to disease activity in children with juvenile idiopathic arthritis (JIA). If your child has JIA, participating could help doctors understand more about the condition and may guide future treatments.
Shanghai, PudongxinquAges 6–16 - NCT06848959Recruiting
Better diagnosis and treatment for children's brain conditions
This study is building a smarter way to diagnose and treat brain conditions in children, such as cerebral palsy, ADHD, and autism. It uses advanced computer models to help doctors provide better care.
NanjingAges 2–18 - NCT06978439RecruitingPhase 4
Blood thinner dosing for children with Kawasaki aneurysm
This study tests the best dose of a blood thinner called rivaroxaban for children with a giant coronary artery aneurysm after Kawasaki disease. The goal is to prevent dangerous blood clots.
Shanghai, Shanghai MunicipalityAges 1 month–18 years - NCT07192952RecruitingPhase 3
Long-term safety of finerenone for children with heart failure
This trial tests a medicine called finerenone to see if it is safe for children and young adults with heart failure when taken for a long time. It may help improve heart function and manage symptoms.
Aurora, ColoradoAges Up to 18 years - NCT05311436Recruiting
Nutrition program study for slum residents in Dhaka
This study tests a nutrition program for pregnant women, adolescent girls, and young children living in Dhaka slums. It is designed to support healthier nutrition during a key growth or pregnancy period.
Dhaka, Dhaka DivisionAges 1 day–39 years - NCT06421103Recruiting
ICG micro-dosing study for children having surgery
This study tests a tiny amount of a dye called Indocyanine Green (ICG) during surgery to see if it safely shows blood flow to the gut and urinary organs. It may help doctors check that these organs are getting enough blood during the operation.
LondonAges Up to 18 years - NCT06072976Recruiting
How feeding affects gut health in babies with bowel conditions
This study looks at whether breast milk or formula helps babies with certain bowel problems heal faster and reach full feeds sooner. It compares how different milk affects the bacteria in a baby's gut.
Seattle, WashingtonAges birth–55 years - NCT05907317RecruitingPhase 3
Protecting the brains of very young newborns on breathing machines
This Phase 3 study tests ways to protect brain health in newborns who are very premature or recently born and need a breathing machine through a tube. It may help reduce the risk of brain injury while they receive intensive care.
MadridAges birth–4 weeks - NCT07008755Recruiting
Inhaled interferon for hand, foot, and mouth disease in children
This trial tests whether breathing in a medication called pegylated interferon helps children with mild hand, foot, and mouth disease recover faster. It is for children ages 1 to 6 who have had symptoms like fever or rash for 3 days or less.
ChengduAges 1–6 - NCT07768865Recruiting
Artery stiffness in young people with kidney disease
This study looks at how stiff the arteries are in children and young adults with chronic kidney disease (CKD) compared to healthy controls. The results may help doctors better understand heart risks and improve care for young people with kidney problems.
London, Greater LondonAges 10–25 - NCT05583721RecruitingPhase 2
PET scan study of heart filling and blood flow in sickle cell
This study uses a PET scan to look for links between abnormal heart “filling” problems and how well blood reaches the heart muscle in people with sickle cell disease. The results may help explain early heart changes in sickle cell and guide future care.
Memphis, TennesseeAges 18–21
Hear when a new Congenital Heart Disease in Children trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for congenital heart disease in children?
- Yes. Clin2 currently lists 84 recruiting congenital heart disease in children studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a congenital heart disease in children trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a congenital heart disease in children trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.