Clinical trials
Congenital Heart Disease in Children clinical trials
Below are recruiting congenital heart disease in children clinical trials, each written for real people, not researchers. We’re tracking 84 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06089902Recruiting
European registry for anomalous aortic origin of coronary arteries
This is a European registry for people with an anomalous origin of a coronary artery from the aorta (AAOCA). It will track how the condition is treated—whether with surgery or monitoring—to learn what works best.
Padova, PDAges Any age - NCT06267859RecruitingEarly Phase 1
New treatments for frequently ill children
This study tests new ways to help children who get sick often (frequently ill children) feel better and avoid common illnesses. It focuses on children who do not have severe chronic diseases.
Tashkent, Yunus-obad DistrictAges 3 days–15 years - NCT06325280Recruiting
Exercise MRI for Kids with Heart Conditions
This study uses an MRI while exercising to check heart and lung fitness in children with heart disease. It helps doctors learn more about how to care for kids who have had a heart transplant or were born with heart problems.
Edmonton, AlbertaAges 10–18 - NCT06431269Recruiting
Screening for developmental disorders in children with heart disease
This study is looking for children aged 1 to 5 years who have congenital heart disease and had heart surgery or a procedure in their first year. A special nurse will check for early signs of developmental delays, to see if this kind of screening is helpful for these children.
MontpellierAges 1–5 - NCT06434207Recruiting
Heart defect study in newborns to understand blood clots
This study looks at tiny particles from cells in newborns with heart defects to understand blood clot risks. It aims to find ways to prevent clots after heart surgery.
Boston, MassachusettsAges 1 day–1 week - NCT06626672Recruiting
Digital Health Program for Kids with Heart Defects
This study uses digital tools to promote healthy habits in children (ages 8–14) with congenital heart disease. It aims to support both the child and their family in staying active and well.
MünchenAges 8–14 - NCT07686341Recruiting
Precision oxygen monitor study for infants
This trial tests a new type of oxygen monitor (pulse oximeter) in babies under 1 year old. It helps doctors better track oxygen levels in critically ill infants to improve care.
Memphis, TennesseeAges birth–1 year - NCT07214376Recruiting
Nerve ablation for pulmonary hypertension from left heart disease
This trial tests a device that uses a catheter to deliver energy to nerves around the pulmonary arteries, aiming to reduce high blood pressure in the lungs caused by left heart failure. It is for people with ongoing heart failure symptoms despite optimal medications.
Houma, LouisianaAges 18–85 - NCT06861998Recruiting
Sleep help before heart surgery for infants and toddlers
This trial tests if helping young children with sleep problems before heart surgery can reduce confusion or agitation after surgery. It is for children ages 0 to 3 who have sleep issues and are scheduled for heart repair surgery.
BeijingAges 1 day–3 years - NCT06879431Recruiting
Sleep help before heart surgery for young children
This study tests if helping babies and toddlers with sleep problems sleep better before heart surgery can lower the risk of confusion or agitation after surgery. It is for children aged 0 to 3 years who have trouble sleeping and are scheduled for heart surgery.
BeijingAges 6–12 - NCT06885307Recruiting
Building a research network for children with heart conditions
This study is building a network of hospitals across China to help children with congenital heart disease. If your child was born with a heart problem and is under 18, they may be able to join and help improve care for kids like them.
Wuhan, HubeiAges Up to 18 years - NCT06918795Recruiting
Fontan Fitness Trial: Home exercise for better heart health
This study tests whether a home-based exercise training program can improve fitness in people with Fontan circulation. Participants will do regular aerobic exercise and be monitored for changes in heart and lung function over time.
Philadelphia, PennsylvaniaAges 10–17 - NCT07023367Recruiting
Parent navigator program for Latino families of babies with heart disease
This study offers a parent navigator program to help Latino families whose baby had early heart surgery. The program aims to support both the child's recovery and the parents' well-being.
Los Angeles, CaliforniaAges birth+ - NCT07115108Recruiting
High-energy feeding for growth and brain development in infants with heart disease
This study tests a special high-energy formula for babies with congenital heart disease who are at nutritional risk. It aims to see if this feeding helps them grow and develop better before and after heart surgery.
Shanghai, Shanghai MunicipalityAges birth–6 months - NCT07193719RecruitingPhase 1/Phase 2
Personalized breathing support for kids after heart surgery
This study tests a personalized breathing technique to improve lung function and heart performance in children who have had heart surgery or are on ECMO. The goal is to find the best way to open up the lungs safely.
BerlinAges birth–18 years - NCT01192048Recruiting
Study genetics in congenital heart disease
This study looks at how genes may contribute to congenital heart disease. It may help researchers better understand causes and risk in families like yours.
Columbus, OhioAges Any age - NCT02852031Recruiting
Care program for newborns needing the Norwood procedure
This trial focuses on improving care for babies born with certain complex heart conditions where only one pumping chamber works. It is meant for babies (including unborn babies) who are planned to have the Norwood procedure, which is a common early surgery.
Birmingham, AlabamaAges Up to 1.3 years - NCT02542683Recruiting
Physical activity program to support children’s brain development
This study looks at whether a structured physical activity program can support thinking and brain development in children around age 2–5. Your child may be eligible if they are having certain surgeries or fit a matched “control” group and do not have specific neurologic or heart-related issues.
New York, New YorkAges 2.5 years–6 years - NCT02923440Recruiting
Donate DNA and help build a congenital heart study database
This study creates a DNA bank and a French database for babies and children with certain types of congenital heart defects, to better understand genetic causes. You’ll be asked to have a blood test and share consent, even though care can continue as usual at the study hospital.
MarseilleAges Any age - NCT07405333Recruiting
Coughing exercises vs breathing device after heart surgery in children
This study compares simple coughing exercises with a breathing device (incentive spirometry) to help children recover lung function faster after heart surgery. It may help reduce complications and shorten hospital stays.
Baghdad, Baghdad GovernorateAges 6–18 - NCT07414251Recruiting
Preparing children for heart procedures
This study looks at how children prepare for heart surgery or a heart catheterization. It will ask families to fill out questionnaires to help improve preoperative care.
Berlin, State of BerlinAges Up to 18 years - NCT07477197Recruiting
Heart Institute Biobank for Adult Congenital Heart Disease
This study collects blood and tissue samples and health information from adults with or at risk for congenital heart disease or related heart conditions. It aims to help researchers better understand these conditions and improve future treatments.
Cincinnati, OhioAges 16 years+ - NCT07556185Recruiting
Testing a home heart health monitoring app for kids
This study tests whether young people with heart conditions can use a home monitoring app called Medly to track their symptoms and weight. The app may help doctors catch problems earlier and keep kids healthier at home.
Toronto, OntarioAges 8–18 - NCT06776822Enrolling by invitation
DNS therapy for asymmetry after heart surgery in children
This trial tests whether a special physical therapy called DNS (Dynamic Neuromuscular Stabilization) can help children aged 6 to 18 who have body asymmetry (uneven movement or posture) after surgery for a congenital heart defect. Participation may improve their balance and muscle control.
PragueAges 6–18
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Common questions
- Are there clinical trials for congenital heart disease in children?
- Yes. Clin2 currently lists 84 recruiting congenital heart disease in children studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a congenital heart disease in children trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a congenital heart disease in children trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.