Clinical trials
Coronary Artery Calcification clinical trials
Below are recruiting coronary artery calcification clinical trials, each written for real people, not researchers. We’re tracking 64 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07276282RecruitingPhase 3
Ziltivekimab for heart attack patients with artery plaque
This trial tests a new drug called Ziltivekimab to see if it can reduce plaque buildup in the heart arteries after a heart attack. It may help prevent future heart problems by targeting inflammation.
BernAges 18 years+ - NCT06678594Recruiting
A standardized method for treating hardened heart artery blockages
This trial is testing a new step-by-step approach (algorithm) to treat hardened, calcified blockages in heart arteries during a stent procedure. The goal is to see if this standardized method helps improve outcomes for patients with these tough-to-treat blockages.
DublinAges 18 years+ - NCT06414551Recruiting
Calcium on CT scan and heart blockage procedure outcomes
This study looks at whether calcium buildup seen on a heart CT scan affects the success of opening a completely blocked artery. It may help guide future treatment for people with similar blockages.
Birmingham, West MidlandsAges 18 years+ - NCT07277114Recruiting
Drug balloon vs stent for hardened arteries after special preparation
This trial compares two treatments for severely calcified coronary arteries: a drug-coated balloon (DCB) and a drug-eluting stent (DES). It is for people who have already had a procedure to crack or soften the calcium (like rotational atherectomy), and whose blood flow looks good afterward.
ShanghaiAges 18 years+ - NCT06939374Recruiting
Freezing heart arteries to stabilize high-risk plaques
This study tests a special cooling balloon to freeze and stabilize dangerous plaques in heart arteries that are not the main cause of your current symptoms. It aims to prevent future heart attacks.
AalstAges 18 years+ - NCT07463664Recruiting
Drug-coated balloons for blocked heart arteries
This trial tests whether a drug-coated balloon, used without a permanent stent, can safely open completely blocked heart arteries that have been blocked for at least 3 months. It may offer an option that avoids leaving a metal stent behind.
Beijing, Beijing MunicipalityAges 18–80 - NCT07302659Recruiting
Comparing two aortic clamping methods in off-pump bypass
This study compares two ways to clamp the aorta during off-pump heart bypass surgery to see which is safer for your brain and body. If you are having bypass surgery without a heart-lung machine, you may be able to join.
BeijingAges 18 years+ - NCT07093788Recruiting
Comparing two ways to treat hard calcium in heart arteries
This trial tests two methods for breaking up heavy calcium buildup in heart arteries before placing a stent. It compares a specialized high-pressure balloon to a device that uses shockwaves.
Lianyungang, JiangsuAges 18–80 - NCT06559332Recruiting
Heart artery checks during aortic valve replacement
This study tests different ways to check for blocked heart arteries in patients getting a new aortic valve through a tube in the leg. It aims to find the best approach to guide treatment.
BernAges 70 years+ - NCT04545112Enrolling by invitation
Testing a new heart bypass graft in people needing multi-vessel CABG
This study tests a new way to connect a bypass graft during heart bypass surgery for people with blocked heart arteries. The goal is to see if the new graft can be safely placed and works well enough to improve outcomes compared with the standard approach.
LeuvenAges 18 years+ - NCT06631755Recruiting
How calcium affects stent healing: an imaging study
This study looks at how calcium buildup in artery walls affects how well a stent heals. Doctors will use special imaging (OCT) right after stent placement and again a month later to check the healing of the tiny metal struts.
BarcelonaAges 18 years+ - NCT05916950Recruiting
Study of a new treatment for blocked leg arteries
This trial studies a device-based treatment approach for people with blocked (narrowed or fully blocked) arteries in the thigh or behind the knee that reduce blood flow to the leg. It may help improve blood flow and walking ability, but you must meet specific artery and imaging requirements.
St. Helena, CaliforniaAges 18 years+ - NCT07062471Recruiting
Shockwave balloon treatment for hardened carotid arteries before stenting
This study tests a special balloon that uses sound waves to break up calcium buildup in the carotid artery (the main artery in your neck) before placing a stent. It's for people who are at high risk for traditional surgery and have heavy calcium deposits in their artery.
Little Rock, ArkansasAges 18 years+ - NCT06919562Recruiting
Better stent placement using imaging and newer scaffolds
This trial tests if using advanced imaging (like OCT or IVUS) to guide placement of a newer type of stent (bioresorbable scaffold) can reduce future stent problems. It is for people with stable coronary artery disease who need a stent in a main heart artery.
DordrechtAges 18 years+ - NCT07159087Enrolling by invitation
New drug balloon for re-narrowed stents
This trial tests a new drug-coated balloon (Genoss SCB) versus an existing one (SeQuent Please NEO) for people whose heart stents have re-narrowed. It aims to see which balloon better keeps the artery open.
Gyeonggi-doAges 19 years+ - NCT05807841Recruiting
AI ultrasound during stent placement in heart artery blockages
This trial tests an artificial-intelligence tool that uses a heart ultrasound to help guide stent treatment. It may help doctors choose the best way to treat blockages and improve stent results for people with symptoms from reduced blood flow to the heart.
Bucheon-siAges 19 years+ - NCT06259019Recruiting
Blood test during heart procedure to find disease markers
This trial uses a special device to take a small blood sample from your heart arteries during a planned procedure. It aims to find unique markers that could help doctors better understand and treat coronary artery disease.
BournemouthAges 18 years+ - NCT06369142Recruiting
Shockwave lithotripsy for severe calcium in heart arteries
This study tests a new method called coronary lithotripsy to break up severe calcium deposits in heart arteries before placing a stent. It may help people with very hard, calcified blockages that are hard to treat with standard stenting.
Heidelberg, Baden-WurttembergAges 18 years+ - NCT06551662Recruiting
Balloon vs. stent for split artery blockages
This trial compares two ways to open a blocked artery that splits into two branches (a bifurcation): using a balloon coated with medicine (drug-coated balloon, or DCB) versus a drug-eluting stent (DES). The goal is to see which approach works better for patients with this type of blockage.
MilanAges 18 years+ - NCT01366404Recruiting
FFR-guided heart procedure study for coronary artery narrowing
This study follows people who have narrowed heart arteries and have a pressure test (FFR) to guide treatment. It may help doctors understand the course of disease when using FFR and choosing a minimally invasive approach.
AnyangAges 35 years+ - NCT06822712Recruiting
Sirolimus-coated balloon for heart artery branch blockages
This trial tests a new balloon coated with sirolimus (a drug that helps prevent re-blockage) for treating blocked arteries at branch points (bifurcations) in the heart. If you have a blocked artery at a branch point, this study may offer a way to treat the side branch without placing a stent there.
Lanzhou, GansuAges 18–80 - NCT06168422Recruiting
Stent study for elderly with severe artery calcium
This study tests a way to open severely hardened arteries in people aged 60 and older using a special tube (stent). It may help if you have complex blockages and are a candidate for angioplasty.
Zhengzhou, HenanAges 60 years+ - NCT07010094Recruiting
Shockwave balloons for hardened heart artery blockages
This trial tests a special balloon that uses shock waves to crack calcium in heart arteries, making it easier to place a stent. It is for people with chest pain or signs of heart strain due to a single, severely blocked artery with dense calcium.
Fujian, XiamenAges 18–85 - NCT07303439Recruiting
Comparing heart artery treatments in people with diabetes
This study compares using a special medicated balloon plus a medicated stent versus using just one of them to open blocked heart arteries in people with diabetes. It aims to find which treatment works better to keep arteries open longer.
Dublin, County DublinAges 18 years+
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Common questions
- Are there clinical trials for coronary artery calcification?
- Yes. Clin2 currently lists 64 recruiting coronary artery calcification studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a coronary artery calcification trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a coronary artery calcification trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.