Clinical trials
Coronary Disease clinical trials
Below are recruiting coronary disease clinical trials, each written for real people, not researchers. We’re tracking 680 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05353946Recruiting
Rotational atherectomy elective vs emergency for heavily calcified blockages
This trial compares doing a special procedure (rotational atherectomy) before an emergency is needed versus using it as a rescue during a heart artery procedure. It is designed for people with very hard, calcified artery blockages and long-term kidney impairment, to see which approach works better and is safer.
MadridAges 18–100 - NCT03945968Recruiting
Risk scores after abdominal surgery for people with health conditions
This study looks at how other health problems affect the chance of postoperative complications after abdominal surgery. It aims to help doctors better predict risk and decide on the safest care for you.
ArkhangelskAges 18 years+ - NCT04220047Recruiting
Surgery changes for preventing irregular heart rhythms during bypass
This trial studies whether removing a small heart pouch area and a specific ligament during off-pump heart bypass surgery improves outcomes. It is meant for people having their first off-pump coronary bypass, without a history of atrial fibrillation.
BeijingAges 18–80 - NCT02038127Recruiting
Heart procedure outcomes tracking registry
This study collects information from people having a heart procedure called percutaneous coronary intervention, or PCI, to learn more about their outcomes and improve future care.
Chuncheon, Gangwon-doAges Any age - NCT06932874RecruitingPhase 4
Metformin for diabetes with heart disease
This trial tests a long-acting metformin pill in people with both type 2 diabetes and coronary heart disease. It aims to see if metformin can safely help control blood sugar in this specific group.
Beijing, Beijing MunicipalityAges 30–75 - NCT04973579Recruiting
Stent plus heart surgery for high risk carotid patients
This trial looks at whether doing carotid artery stenting at the same time as heart surgery is safe and effective for people at high risk of stroke around the time of surgery. It targets people with significant carotid narrowing who also need heart surgery for specific heart problems.
KrakowAges 18 years+ - NCT04417387Recruiting
Check genetics to improve heart disease risk prediction
This study looks at whether adding genetic information to a standard NHS Health Check can better predict a person’s risk of coronary artery disease (CAD). If you qualify, you may be asked to provide genetic information to help refine future risk estimates.
LeicesterAges 40–74 - NCT07796217RecruitingPhase 4
Comparing blood thinners after a heart attack
This study compares two ways to lower the chances of another heart attack: taking the standard medicine (clopidogrel) versus taking a combination of aspirin and a lower dose of a blood thinner (rivaroxaban). If you join, you'll be assigned to one of these options to see which works better for people like you.
Seongnam-si, Gyeonggi-doAges 19 years+ - NCT07614386Recruiting
Radial artery access outcomes in heart and vessel procedures
This registry collects data from patients undergoing heart or blood vessel procedures using a small artery in the wrist (radial or ulnar artery) for access. Researchers track outcomes to better understand the safety and effectiveness of this approach.
Mersin, MezitliAges 18 years+ - NCT06711822Recruiting
Shockwave catheter for calcified heart artery blockages
This study tests a new catheter device (ShockPulse-10) that uses shockwaves to crack calcium in heart arteries before placing a stent. It is designed for people with hard, calcified blockages that are difficult to treat with balloons alone.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07521007RecruitingPhase 2
YN001 treatment for coronary artery disease
This study tests whether a new drug called YN001 can help people with coronary atherosclerosis (narrowing of heart blood vessels). The trial aims to see if it can improve outcomes in people who have early-stage blockages in their heart arteries.
Huntsville, AlabamaAges 18–80 - NCT07479056Recruiting
Fexuprazan to prevent stomach bleeding in heart patients on two blood thinners
This trial tests whether fexuprazan can prevent upper gastrointestinal bleeding in people at high risk who need two antiplatelet drugs for at least 6 months after a heart stent. If you are on dual antiplatelet therapy after a stent and have risk factors like older age, low weight, or history of ulcers, this study may help protect your stomach.
Seoul, Eunpyeong-guAges 20 years+ - NCT07399002Recruiting
Long Nagomi stent study for heart artery blockages
This trial tests a new long stent (Ultimaster Nagomi) for treating long blockages in the heart arteries. It aims to see how well the stent works in real-world patients who need a single stent for a long lesion.
CabueñesAges 18 years+ - NCT06338293RecruitingPhase 4
Inclisiran plus statins for fragile heart plaque
This trial tests if adding inclisiran to your current statin can reduce dangerous, rupture-prone plaque in your heart arteries. It may help if you have a moderate blockage with thin-cap plaque and your LDL cholesterol stays high despite statins.
Nanjing, JiangsuAges 18–80 - NCT06738381Recruiting
Digital prevention program after heart attack or stroke
This trial tests a digital program (using a smartphone or tablet) to help prevent another heart attack or stroke. It is for people who have already had a heart-related event or have known artery plaque buildup.
Drammen, BuskerudAges 18 years+ - NCT05635227Recruiting
Medications during heart surgery to help control breathing and circulation
This study looks at whether giving dexamethasone and olanzapine during certain heart surgeries can improve how blood flow and ventilation (breathing support) are managed. It’s meant to see if these medicines help the body handle heart-lung bypass more safely.
CopenhagenAges 18 years+ - NCT07202754Recruiting
Complex heart procedure study for adults 18-85
This study looks at how often complications happen and long-term survival in people having complex coronary procedures. It may help doctors understand which treatments work best for complex heart disease.
IstanbulAges 18–85 - NCT07045194Recruiting
Study of Virtue balloon for coronary stent re-narrowing
This trial tests a special balloon to treat narrowed areas inside a previously placed heart stent. It may help by reopening the artery without adding another stent.
Gainesville, FloridaAges 18 years+ - NCT07010094Recruiting
Shockwave balloons for hardened heart artery blockages
This trial tests a special balloon that uses shock waves to crack calcium in heart arteries, making it easier to place a stent. It is for people with chest pain or signs of heart strain due to a single, severely blocked artery with dense calcium.
Fujian, XiamenAges 18–85 - NCT06863155Recruiting
A thin heart stent for people on blood thinners
This trial tests a new type of heart stent in people who also take daily blood thinners. The stent is very thin and releases medicine over time to help keep the artery open, and the coating eventually dissolves. It may be a safer option for people on blood thinners who need a stent.
AlbaceteAges 18 years+ - NCT06631157Recruiting
Essential Pro study for routine hospital patients
This trial is studying the Essential Pro device or treatment in patients who are already using it as part of their normal hospital care. The goal is to see how well it works in everyday practice.
Lai Chi KokAges 18 years+ - NCT06177743Recruiting
Coroflex NEO heart stent study
This study monitors patients who receive a Coroflex ISAR NEO stent to track how well it works over time. It helps doctors understand the safety and effectiveness of this specific stent.
Seoul, Songpa-guAges 19 years+ - NCT06084091Recruiting
Measuring heart oxygen levels during open-heart surgery
This study measures oxygen levels in the heart muscle during open-heart surgery using a light-based technique. You may qualify if you are an adult scheduled for this surgery and can provide consent.
Helsinki, UusimaaAges 18–90 - NCT06047028Recruiting
Heart MRI scan to assess tissue health
This study uses a special MRI scan to look at heart muscle metabolism in people with heart failure caused by blocked arteries. It may help doctors better understand which heart tissue is still alive and could recover.
Dallas, TexasAges 20–80
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Common questions
- Are there clinical trials for coronary disease?
- Yes. Clin2 currently lists 680 recruiting coronary disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a coronary disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a coronary disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.