Clinical trials
Coronary Disease clinical trials
Below are recruiting coronary disease clinical trials, each written for real people, not researchers. We’re tracking 680 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05152888RecruitingPhase 4
Testing a cholesterol drug to improve heart blood flow on scans
This trial studies whether lowering LDL (“bad cholesterol”) with a PCSK-9 inhibitor (evolocumab) improves blood flow to the heart, measured by special PET scans. It’s for people over a certain age who have stable coronary artery disease and a higher risk of heart problems.
Boston, MassachusettsAges 50–90 - NCT05997693RecruitingPhase 3
One month of blood thinners after heart bypass surgery
This trial tests whether taking just one month of two blood thinners after coronary artery bypass graft (CABG) surgery is safe and as effective as the standard longer course. It focuses on people having their first bypass surgery who receive at least one vein graft from the leg.
Englewood, New JerseyAges 18 years+ - NCT04505865Recruiting
Mindfulness program to reduce inflammation in heart disease
This trial studies whether a mindfulness (stress-reducing) program can lower “vascular inflammation” (inflammation in blood vessel walls) in people with stable coronary disease. It may help by improving stress and related inflammation markers while you stay on your usual heart medicines.
Boston, MassachusettsAges 45–65 - NCT01621594Recruiting
Testing new radiation methods for heart CT images
This trial studies newer ways to take heart and blood vessel CT scans while using radiation more carefully. It may help improve image quality for people needing coronary CT angiography.
Bethesda, MarylandAges 18–100 - NCT05897333Recruiting
Registry study for isolated coronary artery dilation
This is a “registry” study that collects health information about people who have isolated coronary artery ectasia (an abnormal dilation of a heart artery). It may help doctors better understand what to expect and how these conditions relate to symptoms like chest pain or heart attacks.
AnkaraAges 18–90 - NCT06066450Recruiting
OSFIT Stent for Coronary Artery Blockage
This trial tests a special stent (OSFIT) in people with a blockage near the start of a coronary artery. The goal is to see if the stent works well for this specific location.
SuwonAges 19 years+ - NCT07810621Recruiting
Low cardiac output after heart surgery
This study looks at how well the heart pumps right after bypass surgery and whether a special monitor can help predict problems. It may help doctors support patients better after surgery.
Ankara, AnkaraAges 18 years+ - NCT06520904RecruitingPhase 4
PCSK9 inhibitor for coronary plaque in heart disease
This study tests whether a medication called a PCSK9 inhibitor (a type of drug that lowers bad cholesterol) can improve the buildup of plaque in heart arteries. It may be an option for people with coronary artery disease who have not been helped enough by statins alone.
Ürümqi, XinjiangAges 18–65 - NCT06659367Recruiting
FFR/QFR registry for heart artery assessment
This study collects information from people who have had a standard heart test called FFR to measure blood flow in their arteries. It aims to better understand how this test helps guide treatment.
BelgradeAges 18 years+ - NCT07439133RecruitingPhase 3
Comparing new heart scan with standard tests for coronary disease
This trial is testing a new imaging agent called XTR004 to see if it can accurately find blockages in the heart's arteries. If you have suspected or confirmed stable coronary heart disease, this study may offer a less invasive way to diagnose your condition.
BeijingAges 18–80 - NCT07019350Recruiting
Smart stenting for heart artery branch blockages
This trial tests a new way to treat complex blockages in heart arteries where a side branch is also narrowed. It uses a drug-coated balloon to open the side branch, aiming to improve blood flow and reduce the need for repeat procedures.
GwangjuAges 19 years+ - NCT06864234RecruitingPhase 4
Beta-blockers for chest pain without blocked arteries
This trial tests if beta-blocker medication improves blood flow and reduces resistance in the tiny blood vessels of the heart in people who have chest pain but no major blockages in their arteries.
Aalst, FlandersAges 18 years+ - NCT06049420Recruiting
Lifestyle medicine for rural patients with chronic disease
This trial tests whether exercise therapy can help people with two or more chronic conditions like obesity, diabetes, or heart disease. It's designed for rural patients and requires a referral from your doctor.
Lewisburg, West VirginiaAges 18–64 - NCT05677386Enrolling by invitation
CT heart scan trial to prevent first heart problems
This trial uses a special CT scan of the heart’s arteries to better predict who is at risk of future heart problems. It may help your care team decide how best to lower risk early.
CopenhagenAges 40 years+ - NCT07173062Recruiting
Algae supplement for heart health and gut bacteria
This study tests whether a supplement made from algae can help improve markers of heart health and affect the bacteria in your gut. It is for people age 50 and older who already have a condition like heart disease, kidney disease, or diabetes.
PortoAges 50 years+ - NCT04347200Recruiting
Long-term blood-thinner therapy registry for heart disease
This study follows people with known coronary artery disease to understand how long-term “blood thinner” treatments are used and how they affect health over time. You may be asked to share medical information and come in for follow-up to help researchers compare outcomes.
MoscowAges 18 years+ - NCT07380399Recruiting
Using the ulnar artery for heart tests when the radial artery is blocked
This trial looks at using the ulnar artery in the wrist instead of the radial artery for heart catheterization or stent placement, when the radial artery on that side is blocked. It may be an option for people who cannot use the other arm's radial artery.
AthensAges 18 years+ - NCT06076551Recruiting
Sex differences in small blood vessel problems of the heart
This study looks at how small blood vessels in the heart work differently in men and women who have chest pain but no major blockages in their main heart arteries. The goal is to better understand and treat these smaller vessel issues.
SeoulAges 20–80 - NCT07231939Recruiting
Testing diabetes drugs to protect kidneys after heart procedures
This study is testing whether a class of diabetes medicines called SGLT2 inhibitors (specifically empagliflozin or dapagliflozin) can prevent kidney injury after heart procedures that use contrast dye.
BydgoszczAges 18 years+ - NCT07193693Recruiting
Study on why doctors don't use heart imaging during stent placement
This study looks at reasons doctors may or may not use a special camera inside the heart arteries (called OCT or IVUS) during a procedure to open blocked arteries. It may help understand how to improve care for people with complex blockages.
BergamoAges 18 years+ - NCT06558474Recruiting
Optimizing angioplasty with balloon expansion after stent placement
This trial looks at a technique called post-dilatation, where a balloon is used after placing a stent to make sure it's fully open. It may help people who are having angioplasty (a procedure to open blocked heart arteries). Doctors want to see if using this step more often leads to better results.
Eindhoven, North BrabantAges 18 years+ - NCT04709900Recruiting
Tests for stable chest pain using heart scans and pressure measurements
This trial studies how well different heart tests (imaging the blood flow and measuring blood pressure in the heart) work for people with stable chest pain. It may help guide safer, more accurate evaluation when you are not having a heart attack.
CopenhagenAges Any age - NCT06114615Recruiting
Remote monitoring after heart treatment to prevent future events
This trial tests whether digital tools can help monitor patients after a stent procedure to lower the chance of another heart problem. It aims to make follow-up care easier and more effective.
Sacramento, CaliforniaAges Any age - NCT05845489RecruitingPhase 4
Clopidogrel to prevent heart problems from minor artery plaque
This trial tests whether clopidogrel (a blood-thinning medicine) can prevent future heart attacks or strokes in people who have early, “subclinical” plaque in their heart arteries. You may be considered if scans show plaque but not major artery blockage that needs a procedure.
Seoul, OtherAges 40 years+
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Common questions
- Are there clinical trials for coronary disease?
- Yes. Clin2 currently lists 680 recruiting coronary disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a coronary disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a coronary disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.