Clinical trials
Coronary Disease clinical trials
Below are recruiting coronary disease clinical trials, each written for real people, not researchers. We’re tracking 690 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07463664Recruiting
Drug-coated balloons for blocked heart arteries
This trial tests whether a drug-coated balloon, used without a permanent stent, can safely open completely blocked heart arteries that have been blocked for at least 3 months. It may offer an option that avoids leaving a metal stent behind.
Beijing, Beijing MunicipalityAges 18–80 - NCT05030818RecruitingPhase 4
Study of heart risk changes using a daily polypill
This trial looks at how a daily “polypill” affects coronary (heart blood vessel) risk factors in adults who already take this polypill for prevention after a prior heart event. If you’re eligible, you’ll complete several study visits so the team can compare risk factors over time.
Gijón, Principality of AsturiasAges 18 years+ - NCT05491668Recruiting
Testing heart artery narrowing before planned stent procedure
This study checks how severely blocked a coronary artery is using measurements taken during a planned heart catheterization, to help guide whether and how to do a stent (PCI). It may help doctors choose the best treatment plan for people with about 70% or more narrowing.
Boston, MassachusettsAges 18 years+ - NCT05782582Recruiting
Testing care for long-term heart artery symptoms in primary care
This study looks at people who come to primary care with symptoms that may be caused by long-term narrowing of heart arteries. The goal is to test an approach for identifying and managing this condition earlier or more accurately in everyday care.
LinköpingAges 18 years+ - NCT06529848Recruiting
Exercise for heart symptoms with clear arteries
This trial tests if exercise training can help people who have chest pain or shortness of breath even though their main heart arteries are not blocked. It focuses on those with small vessel disease in the heart, also known as INOCA.
CopenhagenAges 50 years+ - NCT06863545Recruiting
PCSK9 Inhibitors for High-Risk Coronary Plaques on CT
This study tests whether adding a PCSK9 inhibitor (a newer cholesterol-lowering shot) to standard treatment can reduce heart risks in people who have certain high-risk plaque features seen on a CT scan of their heart arteries.
Hangzhou, ZhejiangAges 18 years+ - NCT06915597Recruiting
Drug-coated balloons for coronary artery disease
This trial is studying how well drug-coated balloons work for people with coronary artery disease. It looks at their use in many different situations, including new blockages, re-narrowed stents, and complex cases. The goal is to see if they are a good option for opening blocked arteries.
DenizliAges 18 years+ - NCT07022587Recruiting
Dissolving stent with drug for blocked heart arteries
This trial tests a stent that slowly dissolves after opening a blocked heart artery, releasing a drug to prevent reclogging. It may help people with narrowing in one or two spots that are not too hard or twisted.
Xi'an, ShannxiAges 18–75 - NCT07601867Recruiting
Dapagliflozin to improve heart function after bypass surgery
This trial tests whether a diabetes medication called dapagliflozin can help improve how well the right side of your heart works after off-pump coronary artery bypass grafting surgery (a way to reroute blood around blocked heart arteries). The goal is to see if this drug reduces strain on your heart during recovery.
Pyatigorsk, Stavropol KrayAges 18 years+ - NCT05081115Recruiting
Stress echo imaging for people with heart valve or muscle issues
This trial studies a stress echocardiogram (an ultrasound of the heart during stress) to better understand and improve future heart imaging. It may help by comparing how well the test works for different heart conditions.
BeneventoAges 18–75 - NCT05611307Recruiting
Heart Health in Testicular Cancer Survivors
This study looks at heart health in men who have survived testicular cancer. It compares those who had different treatments (surgery, chemotherapy, or chemotherapy plus a stem cell transplant) to see if there are hidden signs of heart or blood vessel problems.
Indianapolis, IndianaAges 18–99 - NCT04691037Recruiting
CT heart scan to guide care for stable chest pain
This trial studies whether a CT heart scan (CCTA) can better guide treatment decisions for people with stable chest pain caused by blocked heart arteries. It may help your care team choose the next best step based on scan results.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05923489Recruiting
Follow-up angiography after stent placement in high-risk patients
This study checks how routine repeat heart blood-vessel imaging (angiography) after stent placement may help high-risk patients. It is meant for people who had a successful stent procedure and have certain higher-risk heart features.
Hangzhou, ZhejiangAges 18 years+ - NCT05714241Recruiting
Blood tests to study heart pain with blocked-unblocked arteries
This study looks at blood “biomarkers” and platelet function to better understand INOCA (heart-related chest pain despite no major artery blockage). You may be eligible if you have INOCA and are already taking aspirin, and if you haven’t taken certain blood-thinner or platelet-altering medicines recently.
RomeAges 18 years+ - NCT04375306Recruiting
Testing a heart-pressure ratio to choose bypass surgery plan
This trial studies whether a special heart “pressure/flow ratio” test (measured during the procedure) can help doctors choose the best plan for coronary bypass surgery. It may improve how bypass targets the problem blood vessels, but only if certain heart and health factors fit the study rules.
BonheidenAges 18 years+ - NCT06649305Recruiting
Study of vulnerable plaque in heart arteries of people with diabetes
This study uses a special camera (OCT and NIRS) inside heart arteries to look for dangerous plaque in people with diabetes. It may help doctors decide the best treatment to prevent heart attacks.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06657326Recruiting
New stent for high bleeding risk patients
This trial tests a new type of stent (BioFreedom Ultra) compared to a standard one (BioFreedom) in people who have a high risk of bleeding. Both stents release medicine to keep arteries open, and the study checks if the newer stent works better with a shorter course of blood thinners.
Johor Bahru, JohorAges 18 years+ - NCT06775028Recruiting
Integrated care for older adults with atrial fibrillation
This trial is testing a new approach to care for older adults with atrial fibrillation (an irregular heartbeat) who also have other health conditions. It aims to see if a more integrated, team-based care plan helps improve their overall health and quality of life.
HaskovoAges 65 years+ - NCT07476040Recruiting
Better care for new stable chest pain
This trial tests a new way to manage stable chest pain that started recently. It aims to improve diagnosis and treatment for people suspected of having coronary artery disease.
AugsburgAges 30 years+ - NCT07772570Recruiting
Studying blood markers in coronary artery disease
This study collects blood samples and images from patients with heart muscle damage or those undergoing coronary angiography. The goal is to find new biomarkers that could improve diagnosis and treatment of coronary artery disease.
OxfordAges 18–90 - NCT06585917Enrolling by invitation
Comparing two sheath sizes for wrist artery heart procedures
This trial compares two sizes of small tubes (called sheaths) used during a heart procedure to open blocked arteries. The procedure is done through a tiny artery in your wrist, and the goal is to see if a smaller tube works just as well with fewer side effects.
Beijing, Beijing MunicipalityAges 18–80 - NCT05152888RecruitingPhase 4
Testing a cholesterol drug to improve heart blood flow on scans
This trial studies whether lowering LDL (“bad cholesterol”) with a PCSK-9 inhibitor (evolocumab) improves blood flow to the heart, measured by special PET scans. It’s for people over a certain age who have stable coronary artery disease and a higher risk of heart problems.
Boston, MassachusettsAges 50–90 - NCT05997693RecruitingPhase 3
One month of blood thinners after heart bypass surgery
This trial tests whether taking just one month of two blood thinners after coronary artery bypass graft (CABG) surgery is safe and as effective as the standard longer course. It focuses on people having their first bypass surgery who receive at least one vein graft from the leg.
Englewood, New JerseyAges 18 years+ - NCT04330287Recruiting
Study of heart health in adults aging with HIV
This study looks at how aging affects heart health in people who have HIV. It may help researchers find better ways to prevent or monitor heart problems over time.
Essen, NordrheinwestfalenAges 18 years+
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Common questions
- Are there clinical trials for coronary disease?
- Yes. Clin2 currently lists 690 recruiting coronary disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a coronary disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a coronary disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.