Clinical trials
Coronary Heart Disease clinical trials
Below are recruiting coronary heart disease clinical trials, each written for real people, not researchers. We’re tracking 472 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07462260RecruitingPhase 2/Phase 3
Sildenafil for severe pulmonary hypertension from rheumatic valve disease
This trial tests if sildenafil can help people with severe pulmonary hypertension caused by rheumatic valvular heart disease. It aims to see if the drug improves symptoms and heart function.
Hyderābād, SindhAges 18 years+ - NCT07486791Recruiting
Baduanjin exercise for heart health after heart attack
This study tests whether a gentle exercise called 'Lying-Sitting-Standing' Baduanjin can improve heart and lung function and quality of life in people who have had a heart attack and also have heart failure.
Taiyuan, ShanxiAges Up to 85 years - NCT06822712Recruiting
Sirolimus-coated balloon for heart artery branch blockages
This trial tests a new balloon coated with sirolimus (a drug that helps prevent re-blockage) for treating blocked arteries at branch points (bifurcations) in the heart. If you have a blocked artery at a branch point, this study may offer a way to treat the side branch without placing a stent there.
Lanzhou, GansuAges 18–80 - NCT06991322Recruiting
A device to treat chest pain from small heart vessels
This study tests a small metal device (called a coronary sinus reducer) that is placed in a vein of the heart to help people with ongoing chest pain caused by small blood vessel problems, which don't get better with standard medicines. It aims to improve blood flow and reduce pain.
UtrechtAges 18 years+ - NCT07521007RecruitingPhase 2
YN001 treatment for coronary artery disease
This study tests whether a new drug called YN001 can help people with coronary atherosclerosis (narrowing of heart blood vessels). The trial aims to see if it can improve outcomes in people who have early-stage blockages in their heart arteries.
Huntsville, AlabamaAges 18–80 - NCT05635227Recruiting
Medications during heart surgery to help control breathing and circulation
This study looks at whether giving dexamethasone and olanzapine during certain heart surgeries can improve how blood flow and ventilation (breathing support) are managed. It’s meant to see if these medicines help the body handle heart-lung bypass more safely.
CopenhagenAges 18 years+ - NCT06338293RecruitingPhase 4
Inclisiran plus statins for fragile heart plaque
This trial tests if adding inclisiran to your current statin can reduce dangerous, rupture-prone plaque in your heart arteries. It may help if you have a moderate blockage with thin-cap plaque and your LDL cholesterol stays high despite statins.
Nanjing, JiangsuAges 18–80 - NCT07010094Recruiting
Shockwave balloons for hardened heart artery blockages
This trial tests a special balloon that uses shock waves to crack calcium in heart arteries, making it easier to place a stent. It is for people with chest pain or signs of heart strain due to a single, severely blocked artery with dense calcium.
Fujian, XiamenAges 18–85 - NCT07479056Recruiting
Fexuprazan to prevent stomach bleeding in heart patients on two blood thinners
This trial tests whether fexuprazan can prevent upper gastrointestinal bleeding in people at high risk who need two antiplatelet drugs for at least 6 months after a heart stent. If you are on dual antiplatelet therapy after a stent and have risk factors like older age, low weight, or history of ulcers, this study may help protect your stomach.
Seoul, Eunpyeong-guAges 20 years+ - NCT00001853Recruiting
Heart Disease Risk Factors in Black Adults
This study examines why Black men and women have different heart disease risk factors, focusing on weight, cholesterol levels, and diabetes risk. Researchers want to understand these differences to help prevent heart disease in Black communities.
Bethesda, MarylandAges 18–70 - NCT07222683Recruiting
How kidney transplant affects heart blood vessel health
This study looks at how receiving a kidney transplant changes the health of small blood vessels in the heart. It may help people with advanced kidney disease understand the benefits of transplant on their heart health.
Boston, MassachusettsAges 18 years+ - NCT05437965Recruiting
Registry study for repeat coronary blockages after stents
This study follows adults who have fast, unexplained re-narrowing of a coronary stent, to better understand what causes it and how to monitor it. You may help by allowing the study team to collect medical information over time.
Beijing, Beijing MunicipalityAges 18 years+ - NCT04976348Recruiting
Heart monitoring registry for teens and adults with heart symptoms
This study registers people who are referred to cardiology or genetics for heart-failure–type symptoms or heart/cardiogenetic screening. It helps doctors understand how monitoring platforms may support diagnosis and follow-up.
Maastricht, LimburgAges 16 years+ - NCT01399385Recruiting
MRI and heart scans to test possible heart disease
This study tests new or improved heart imaging methods to understand whether people have heart-related blood vessel disease. It may help by comparing scan results to your health history and other testing to better spot heart problems earlier.
Bethesda, MarylandAges 18–100 - NCT07077811Enrolling by invitation
Pulsed field ablation for heart failure with preserved pumping strength
This trial tests a new procedure called pulsed field ablation for people who have both persistent atrial fibrillation and a type of heart failure (HFpEF). It aims to see if this ablation safely helps control the heart rhythm.
Nantong, JiangsuAges 18–80 - NCT07265349RecruitingPhase 1/Phase 2
Stem cells plus bypass surgery for chronic heart failure
This trial tests whether injecting stem cells from umbilical cord tissue into the heart muscle during bypass surgery can improve heart function in people with chronic heart failure. It is for patients who are already scheduled for bypass surgery and have a weakened heart pump (LVEF between 21% and 40%).
Shanghai, Shanghai MunicipalityAges 18–80 - NCT05650411Recruiting
Test new drug-eluting stent with less blood thinner
This study compares a new type of “drug-eluting” stent (a tiny scaffold that slowly releases medicine) and a single blood-thinner plan versus the usual two-drug blood thinner plan after stent placement in the left main coronary artery. It aims to see if the simpler plan can work while keeping the stent safe.
Zurich, Canton of ZurichAges 18 years+ - NCT07063147Recruiting
Heart ultrasound for stable chest pain management
This study uses a heart ultrasound (TTE) to help doctors better manage stable chest pain. If you have chest pain that may be from a blocked artery but haven't had a heart attack or heart procedures before, this trial could help improve your care.
TianjinAges 18 years+ - NCT07397845Recruiting
Stents vs drug-coated balloons for small or complex heart vessels
This trial compares two treatments—stents and paclitaxel-coated balloons—for people with narrowed heart arteries that are small, long, or complex. It aims to find which option works better to restore blood flow.
Lucerne, Canton of LucerneAges 18 years+ - NCT06708000Enrolling by invitationPhase 3
Personalized testing for new chest pain
This trial compares a personalized evaluation approach to standard care for people with new chest pain who might have heart disease. It aims to see if tailoring tests can improve diagnosis and outcomes.
HerningAges 30–75 - NCT06434935Enrolling by invitationEarly Phase 1
Trial of a new bypass graft for heart surgery
This trial tests a new artificial blood vessel for heart bypass surgery. If you need a bypass and meet the health requirements, you may be able to receive this experimental graft.
AsunciónAges 45–75 - NCT06641843Enrolling by invitation
Heart stress test using MRI for children with heart disease
This study uses magnetic resonance imaging (MRI) to look at blood flow to the heart muscle during stress in children with certain heart conditions. It may help doctors better understand how the heart is working.
Chengdu, SichuanAges Up to 18 years - NCT06249932RecruitingPhase 4
Empagliflozin for heart failure and end-stage kidney disease
This trial tests whether empagliflozin, a medication for heart failure, can help people who also have end-stage kidney disease and are on dialysis. It aims to see if the drug improves heart function in this group.
Hsinchu, TaiwanAges 20 years+ - NCT06249945RecruitingPhase 4
Empagliflozin for heart failure with preserved ejection fraction and dialysis
This trial tests whether a medicine called empagliflozin (used for diabetes and heart failure) can help people with both heart failure (with preserved pumping ability) and end-stage kidney disease who are on dialysis. The study looks at how the drug affects heart function and overall well-being.
HsinchuAges 20 years+
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Common questions
- Are there clinical trials for coronary heart disease?
- Yes. Clin2 currently lists 472 recruiting coronary heart disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a coronary heart disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a coronary heart disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.