Clinical trials · Maryland
COVID-19 clinical trials in Maryland
We’re tracking 26 recruiting covid-19 studies with a site in Maryland — including Phase 1, Phase 1/Phase 2, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Maryland
- NCT03808922RecruitingPhase 3
DAS181 treatment for COVID-19 lung infection in immune-compromised adults
This Phase 3 trial tests DAS181 to treat lower lung (chest) viral infections in people with weakened immune systems, including a COVID-19 subgroup. It may help by targeting certain viruses in the lungs, but joining depends on your oxygen needs, recent diagnosis, and other safety factors.
Baltimore, MarylandAges Any age - NCT05197621Recruiting
Study how COVID-19 affects pregnancy and newborn outcomes
This study looks at how COVID-19 and COVID vaccination during pregnancy may affect mothers and newborns. Your team will collect health information around delivery to understand what outcomes are most common.
Baltimore, MarylandAges 14–55 - NCT05977179Recruiting
Diet program for long-COVID fatigue and poor diet quality
This study tests whether improving diet quality can reduce fatigue and symptoms in people with long-COVID (post-acute COVID-19 syndrome). It may help if your diet quality is currently low and your fatigue is moderate to severe.
Baltimore, MarylandAges 50–94 - NCT04582903Recruiting
Send-in sample collection study for immune response to respiratory viruses
This study collects sent-in samples to better understand how your immune system responds during a COVID-19–like illness and after you recover. It may help researchers learn why some people get sick and others stay uninfected, and how immune protection works over time.
Rockville, MarylandAges 1 day–99 years - NCT06441955RecruitingPhase 4
Long Covid prevention and health support trial
This trial tests a care program designed to help people who continue to have symptoms after recovering from COVID-19. It aims to prevent long-term health problems and improve well-being.
Bethesda, MarylandAges 18–65 - NCT07013474RecruitingPhase 3
Study of ibuzatrelvir for immunocompromised adults with COVID-19
This trial tests an investigational medicine called ibuzatrelvir for adults with COVID-19 who have a weakened immune system. The study aims to see if it helps them recover and avoid severe illness.
Baltimore, MarylandAges 18 years+ - NCT05425264Recruiting
Home exercise coaching by video after COVID
This trial tests a home-based exercise and physical therapy program delivered by video after a COVID-19 infection. It may help you rebuild strength and breathing safely, especially if you also have certain long-term health conditions.
Baltimore, MarylandAges 50–85 - NCT06128928Recruiting
Boosting COVID-19 vaccines in Latino communities
This study tests whether connecting with friends and health workers can help more Latino people in Maryland get vaccinated or boosted against COVID-19. It aims to reach both those who are already vaccinated and those who are hesitant.
Baltimore, MarylandAges 18 years+ - NCT05369611Enrolling by invitation
Share your COVID-19 experiences in a long-term study
This study asks people already enrolled in the NIEHS SELF cohort to answer a questionnaire about their COVID-19 experiences. Your answers can help researchers understand how COVID-19 affected people in this group.
Bethesda, MarylandAges 23–35 - NCT06679140RecruitingPhase 3
Study of Ibuzatrelvir for COVID-19 in high-risk patients
This trial tests if a new medicine called ibuzatrelvir can help people with COVID-19 who have certain health risks avoid severe illness. It is for patients who cannot or choose not to take another COVID-19 pill called Paxlovid.
Columbia, MarylandAges 12 years+ - NCT05261139RecruitingPhase 3
Trial for PF-07321332 for children at risk from COVID-19
This trial studies whether PF-07321332 (with ritonavir) helps children under 18 who have COVID-19 at home but are at high risk of severe illness. It looks at whether starting treatment early can reduce progression to worse disease.
Baltimore, MarylandAges birth–17 years - NCT06667700RecruitingPhase 3
A study of the antiviral molnupiravir for high-risk people with COVID-19
This study tests an antiviral pill called molnupiravir to see if it can prevent severe COVID-19 in people who are at high risk and cannot take Paxlovid. If you have mild to moderate COVID-19 symptoms and certain health risks, you may be able to join.
Annapolis, MarylandAges 18 years+ - NCT04790240RecruitingPhase 1/Phase 2
Herbal treatment aimed to reduce COVID-19 inflammation
This early-stage trial studies whether certain medical herbs can lower inflammation in people with recent COVID-19 and help the immune system better fight the virus. You may be able to join whether or not you take standard COVID medicines, but you would need to complete the herb plan and provide specific lab and scan results.
Rockville, MarylandAges Any age - NCT05880108Recruiting
Behavior program to help COVID recovery in Veterans
This study tests whether a behavioral (lifestyle) program can improve recovery from COVID-19, especially for Veterans with different body weights. It looks at people who either have never had COVID before or had COVID more than 90 days ago.
Baltimore, MarylandAges Up to 80 years - NCT06920628RecruitingPhase 1
Brain scan study for long COVID neurological symptoms
This study uses a special PET scan to look at brain inflammation in people with neurological symptoms after COVID-19. It aims to understand how inflammation might be linked to ongoing problems like brain fog or memory issues.
Bethesda, MarylandAges 18–70 - NCT07149428Enrolling by invitation
Deep study of smell loss causes using brain scans
This study uses brain imaging and electrical recordings to understand the brain's role in smell loss from any cause—like COVID, sinus problems, or chemotherapy. You may be eligible if you have any degree of smell loss lasting under a year.
Bethesda, MarylandAges 18–99 - NCT04278404Recruiting
Drug safety study for children already on certain medicines
This study measures how certain medicines move through the body and checks their safety in children. It may help doctors better understand dosing and side effects in kids who are already receiving these treatments, or in some kids who recently tested positive for COVID-19.
Baltimore, MarylandAges birth–20 years - NCT04453657Enrolling by invitation
Tele-wellness app for child care families during COVID-19
This study tests a phone/tablet program to help family child care providers and parents support kids’ health, family connection, and readiness for school during COVID-19. You may be able to join if you’re in Baltimore City and your child care program is part of the study’s COVID-related approved group.
Baltimore, MarylandAges 3–99 - NCT01306084Recruiting
Study of viral infections in healthy and immune-compromised people
This trial studies how viruses affect the body, and how the immune system responds, in both healthy people and people with weakened immunity. It may include people who currently have a suspected or recent viral infection, close contacts, people around the time of a viral vaccine, and healthy adults used for comparison.
Bethesda, MarylandAges 6 months–120 years - NCT04391816Recruiting
Study of how alcohol use changed during the COVID-19 pandemic
This study follows people over time to understand how the COVID-19 pandemic affected alcohol use and related health or behaviors. You may help by answering short surveys by phone or online on a regular schedule.
Bethesda, MarylandAges 18–100 - NCT07536308RecruitingPhase 1
Nasal COVID-19 booster vaccine safety trial
This trial tests a new nasal spray COVID-19 booster vaccine. It aims to see if the vaccine is safe and produces a strong immune response when given through the nose and inhaled, in people who have already been vaccinated.
Baltimore, MarylandAges 18–64 - NCT05123755RecruitingPhase 2
Testing a new medicine in hospitalized pneumonia patients needing oxygen
This Phase 2 trial tests an investigational medicine (given in increasing doses) for hospitalized people with pneumonia who need supplemental oxygen. It aims to see if the medicine is safe and potentially helps the pneumonia process in the early hospital period.
Hyattsville, MarylandAges 18 years+ - NCT05141058RecruitingPhase 1
T cell therapy to help prevent COVID-19 after transplant
This Phase 1 trial tests a donated immune-cell treatment (T cells) to help immunocompromised people fight or resist COVID-19 after they recently received a bone marrow or stem cell transplant. It aims to see if the treatment is safe and if it helps the body respond better to the virus.
Baltimore, MarylandAges 2–80 - NCT05266222Recruiting
Collecting respiratory virus samples for a research library
This study collects samples from people who have or might have a cold/respiratory virus, then stores them for future research. It may help researchers better understand respiratory germs and develop better treatments.
Bethesda, MarylandAges 3 years+
COVID-19 trials by city in Maryland
Where these studies are running in Maryland
Institutions with a site for the recruiting covid-19 studies listed above.
- National Institutes of Health Clinical Center · 6 studies
- Johns Hopkins Hospital · 4 studies
- Johns Hopkins University · 3 studies
- Baltimore VA Medical Center · 2 studies
- Jadestone Clinical Research · 2 studies
- All Natural Medicine Clinic, LLC
- Annapolis Internal Medicine
- Centennial Medical Group
What taking part in a covid-19 study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
COVID-19 trials in other states
Common questions
- Are there covid-19 clinical trials in Maryland?
- Yes. We're currently tracking 26 recruiting covid-19 studies with a site in Maryland, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a covid-19 study in Maryland?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Maryland to take part?
- Not necessarily. These studies have a site in Maryland, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a covid-19 trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New covid-19 studies open in Maryland regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.