Clinical trials
COVID clinical trials
Below are recruiting covid clinical trials, each written for real people, not researchers. We’re tracking 337 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04445285RecruitingPhase 2
Test drops to thin lung mucus in severe COVID-19
This Phase 2 trial tests rhDNase (a medication similar to Pulmozyme) to improve outcomes and reduce the risk of death in people with severe COVID-19 causing breathing failure. It’s meant for adults who need high-flow oxygen or a breathing machine.
Mobile, AlabamaAges 18 years+ - NCT04871932Recruiting
Study of immune response to a COVID-19 vaccine
This trial studies how your immune system responds after a COVID-19 vaccine. It uses detailed blood tests to understand what changes happen in your immune cells and may help researchers improve future vaccines.
ShanghaiAges 18–50 - NCT04558450Recruiting
Study how COVID-19 affects blood vessel stiffness and aging
This study looks at how having COVID-19 may affect your blood vessels over the following months. It may help doctors understand long-term “vascular aging” and who is most at risk, based on how sick you were during your COVID illness.
NancyAges 18 years+ - NCT04746066Recruiting
Study of thalassemia, sickle cell, and inherited anemia with COVID
This observational study looks at people with thalassemia, sickle cell disease, or other inherited anemia who have COVID-19. It aims to learn how COVID affects these conditions and may help improve care planning.
GenovaAges Any age - NCT04586413Recruiting
Help build and study a quality-of-life tool after COVID-19
This study will collect information from adults who had COVID-19 (confirmed by a test or diagnosis) to develop and improve a questionnaire about life after infection. Your answers may help researchers better track symptoms and quality of life over time.
OxfordAges 18 years+ - NCT05061329Recruiting
Learn how the nose’s microbes relate to health and disease
This study explores the tiny living organisms (microbes) in your nose and how they may be linked to health problems. It may help researchers better understand disease triggers and potential new prevention or treatment ideas.
Holstebro, Central JutlandAges 18 years+ - NCT04987957Recruiting
Music therapy to reduce anxiety during COVID-19
This study tests whether listening to music can help lower anxiety levels in people experiencing stress during the COVID-19 pandemic. You may be able to join if you’re a midwife or nurse and can complete online surveys.
BoluAges Any age - NCT04443179Recruiting
Baby brain scans in England to study early development
This study does brain imaging (brain scans) in babies to better understand early brain development and how factors like family history and COVID-19 might relate to development. It may help researchers learn which babies could need extra support later.
LondonAges 16–75 - NCT07795021Recruiting
Stroke care during the COVID-19 pandemic
This study looks at how stroke care was given during the COVID-19 pandemic. It aims to understand if treatments and outcomes changed, which may help improve care for people with stroke in future health emergencies.
PragueAges Any age - NCT07783074Recruiting
Fatigue study using digital outcomes in multiple sclerosis and long COVID
This study is investigating fatigue using digital outcomes in people with multiple sclerosis, long COVID, and healthy volunteers. Participants must own a smartphone, be fluent in German or English, and be willing to provide informed consent. Exclusion criteria include having taken certain medications recently, being pregnant or lactating, or having additional health conditions that could affect fatigue or the autonomic nervous system.
Basel, BaselAges 18–65 - NCT07743580RecruitingPhase 3
Secutrelvir for covid-19 patients at high risk
This trial tests a new antiviral pill, secutrelvir, for people with mild to moderate covid-19 who are at higher risk of getting seriously ill. It aims to see if the drug can prevent hospitalization or severe disease.
Coral Gables, FloridaAges 12 years+ - NCT07739446Enrolling by invitation
Do face masks help prevent catching the flu or COVID-19?
This trial looks at whether wearing surgical masks when out in public can reduce your chances of getting the flu or COVID-19. If you join, you'll be assigned by chance to either wear a mask outside for 3-4 months or not wear one, and you'll be tested if you get sick.
ChibaAges 20–49 - NCT04344912Recruiting
Study of COVID-19 effects on heart emergency care
This study looks at how the COVID-19 outbreak affected care for people admitted to the cardiac intensive care unit. It may help hospitals improve how they plan and respond during major outbreaks.
ParisAges 18 years+ - NCT06667063Recruiting
Immune response study for COVID-19 and flu
This study looks at how your immune system responds to COVID-19 or the flu. It may help researchers understand these infections better, whether you are currently sick or healthy.
Wuhan, HubeiAges 18 years+ - NCT07678619Enrolling by invitation
Smart tools for infectious disease decisions
This study tests a smart analysis system to help local health officials make better decisions during infectious disease outbreaks. It aims to see if this tool improves speed and accuracy in responding to diseases like COVID-19, mpox, or flu.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07651761Enrolling by invitation
Vaccine Talk Training for Primary Care Doctors
This study tests whether special training helps primary care doctors have better conversations with patients about flu and COVID-19 vaccines. You may be eligible if you're a patient who visits a participating clinic during the 2026–2027 vaccine season.
Worcester, MassachusettsAges 18 years+ - NCT07610967Recruiting
Light therapy for respiratory infection protection
This study tests a mouthpiece that uses light to help the immune system fight respiratory infections. It may reduce the chance of getting sick.
Nellis Air Force Base, NevadaAges 18 years+ - NCT05833217Recruiting
Study for persistent COVID symptoms with insulin resistance
This trial studies people who have ongoing effects after COVID (often called PASC) and may be related to weight and insulin resistance. It may help researchers find better ways to understand the condition and improve treatment.
Palo Alto, CaliforniaAges 18–80 - NCT07599449Recruiting
Tracking respiratory infections in French primary care
This study tracks viruses that cause sudden colds and flu-like illnesses during winter months in France. Researchers collect information from patients seen by participating doctors to better understand which respiratory viruses are circulating and help prepare for future outbreaks.
ParisAges Any age - NCT07597876Recruiting
COVID-19 Patient Registry and Data Collection Study
This study collects medical information from COVID-19 patients to help doctors better understand the disease and improve treatment. You'll be asked about your health history and how COVID-19 has affected you.
PaviaAges Any age - NCT04890483Recruiting
Brain stimulation to ease pain and fatigue after COVID
This study tests whether a noninvasive brain stimulation treatment can reduce fatigue and body pains after COVID in people with autoimmune diseases. It may help symptoms by changing brain activity without surgery.
São PauloAges 18–80 - NCT07536308RecruitingPhase 1
Nasal COVID-19 booster vaccine safety trial
This trial tests a new nasal spray COVID-19 booster vaccine. It aims to see if the vaccine is safe and produces a strong immune response when given through the nose and inhaled, in people who have already been vaccinated.
Decatur, GeorgiaAges 18–64 - NCT06693362RecruitingPhase 1
Stem cell therapy for severe viral pneumonia
This trial tests whether injecting stem cells from the womb's blood supply can help treat severe viral pneumonia. It aims to improve recovery for people who are very sick and need hospital care.
Shanghai, Shanghai MunicipalityAges 18–85 - NCT07529197Recruiting
Study of Immunoadsorption Treatment for Post-Infectious ME/CFS
This study observes how a blood-cleaning treatment called immunoadsorption works in patients with ME/CFS (severe fatigue condition) who have specific immune markers. Researchers will track whether this treatment helps reduce symptoms and improve daily functioning.
Berlin, State of BerlinAges 18–65
Hear when a new COVID trial opens
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Common questions
- Are there clinical trials for covid?
- Yes. Clin2 currently lists 337 recruiting covid studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a covid trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a covid trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.