Clinical trials
Long COVID Syndrome clinical trials
Below are recruiting long covid syndrome clinical trials, each written for real people, not researchers. We’re tracking 50 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07726082Recruiting
A group program to help with long-term fatigue
This study tests a new way to help people with long-term fatigue that gets in the way of daily life. It uses a group program that focuses on making small, helpful choices to feel better.
BaselAges 18–65 - NCT04806620Recruiting
Online app study for brain inflammation lifestyle data
This study uses a digital platform (app/website) to collect lifestyle and symptom information to better understand brain inflammation. You may qualify if you have certain conditions like Long COVID, migraines, autoimmune disease, inflammatory gut issues, mood disorders, or if you are a healthy comparison person.
Delafield, WisconsinAges 2 years+ - NCT04978571Recruiting
Electrical nerve stimulation for long-lasting concussion symptoms
This study tests whether a device that delivers gentle electrical signals to nerves through the skin can help children and teens with concussion symptoms that have lasted at least 3 months. You may be asked to attend clinic visits for the nerve stimulation setup if you meet the safety and scheduling requirements.
Orange, CaliforniaAges 11–18 - NCT05566392Recruiting
Studying long-term recovery in children after COVID-19
This study looks at how long “long COVID” affects children over time. It may help doctors better understand what symptoms last and what support could improve recovery.
TaipeiAges 6–18 - NCT05741112Recruiting
Long COVID wearable study to track symptoms and help daily management
This study uses a wearable device to track symptoms and patterns in people with Long COVID, ME/CFS, and/or POTS. The goal is to see how wearable feedback and tracking tools may help you manage your symptoms.
La Jolla, CaliforniaAges 18 years+ - NCT05926505RecruitingPhase 2/Phase 3
Anakinra for lingering symptoms after COVID-19
This Phase 2/3 trial studies whether anakinra can improve ongoing (post-acute) COVID-19 symptoms lasting for more than two months. It mainly looks for better safety and symptom improvement in people with specific inflammation and lung-related findings.
JenaAges 18 years+ - NCT05931497Recruiting
Sauna heat treatment for long COVID fatigue
This trial tests whether regular sauna sessions using infrared heat can reduce fatigue from long COVID. You may be eligible if you have ongoing fatigue after a confirmed or strongly suspected COVID infection and can safely spend time lying in a sauna.
Boston, MassachusettsAges 18–65 - NCT05977179Recruiting
Diet program for long-COVID fatigue and poor diet quality
This study tests whether improving diet quality can reduce fatigue and symptoms in people with long-COVID (post-acute COVID-19 syndrome). It may help if your diet quality is currently low and your fatigue is moderate to severe.
Baltimore, MarylandAges 50–94 - NCT06156176Recruiting
Exercise for COVID-19 fatigue: a feasibility study
This study tests whether a personalized exercise program can help reduce fatigue after a COVID-19 infection. You'll work with a coach over video calls to see if gentle activity can improve your energy levels.
London, OntarioAges 18 years+ - NCT06456502Recruiting
Non-invasive brain stimulation for long COVID symptoms
This trial tests whether a gentle, non-invasive brain stimulation device can help relieve long COVID symptoms. It involves wearing special gloves and socks that deliver mild electrical pulses to improve how you feel.
Alcorcón, MadridAges 18 years+ - NCT06492798RecruitingPhase 1/Phase 2
Stem cells for Long COVID: a safety and effectiveness study
This study tests whether a single infusion of mesenchymal stem cells can help with Long COVID symptoms—without causing serious side effects. It’s for people who are still struggling with COVID-related health problems months after their initial infection.
ShanghaiAges 18–70 - NCT06511050RecruitingPhase 1/Phase 2
Testing Lumbrokinase for Long COVID, Lyme, and Chronic Fatigue
This trial tests a supplement called Lumbrokinase (derived from earthworms) to see if it helps reduce symptoms in people with Long COVID, post-treatment Lyme disease syndrome, or ME/CFS. It may benefit those whose daily life is significantly affected by these conditions.
New York, New YorkAges 18 years+ - NCT06631287RecruitingPhase 3
Testing baricitinib for persistent long COVID symptoms
This trial tests whether the anti-inflammatory drug baricitinib can improve persistent long COVID symptoms like brain fog, fatigue, and shortness of breath. You may qualify if you had COVID-19 at least 6 months ago and still have bothersome symptoms that affect your daily life.
Tucson, ArizonaAges 18 years+ - NCT06864156Recruiting
Molecules and vitamin levels in long COVID with brain fog
This study looks at certain molecules (called microRNAs) and vitamin B12 levels in people who have ongoing brain-related symptoms like depression, anxiety, or fatigue after a COVID-19 infection. It may help understand why some people have long-lasting symptoms and could lead to better treatments.
Mexico City, Mexico CityAges 18–65 - NCT06871293Recruiting
Long Covid recovery: rehab with coaching
This study tests a program of rehab exercises and memory/thinking activities, along with coaching messages, to help people with Long Covid feel better and function in daily life. You may qualify if you had Covid, have high blood pressure or diabetes, and still have symptoms like fatigue or trouble thinking for at least 4 weeks.
Bogotá, Bogotá DCAges 18–80 - NCT06883513Recruiting
Osteopathic therapy for long COVID symptoms
This trial tests if gentle hands-on treatment (osteopathic manipulative therapy) can help relieve long-lasting COVID symptoms like fatigue, brain fog, and body pain.
Louisville, KentuckyAges 18 years+ - NCT06928272RecruitingPhase 3
Long COVID drug study for adults 18 to 65
This study tests whether a commonly used drug (repurposed) can help improve Long COVID symptoms like fatigue, breathing problems, or brain fog. It is for adults 18 to 65 who had COVID-19 in the past 4 years and still have symptoms after 3 months.
San Diego, CaliforniaAges 18–65 - NCT06940609RecruitingPhase 2
Brain scan study for Long COVID brain fog
This trial studies if brain scans can help understand 'brain fog' in Long COVID. It also looks at how a gentle magnetic stimulation might affect symptoms. If you have ongoing thinking problems after COVID, this study may help find new ways to help.
Albuquerque, New MexicoAges 18–80 - NCT06960928RecruitingPhase 3
Low dose sirolimus for long COVID
This trial tests if a low dose of sirolimus, a medicine that calms the immune system, can help people with long COVID. If you have had long COVID symptoms for at least 6 months, like severe fatigue, brain fog, or chest pain, you may be able to join.
New York, New YorkAges 18 years+ - NCT07013903Recruiting
Hydrotherapy for post-COVID recovery
This trial tests if Kneipp hydrotherapy (a type of water treatment) helps people recover from post-COVID syndrome. You would receive this therapy during a rehabilitation stay and answer questions on your smartphone.
Schönau am Königssee, BavariaAges 18 years+ - NCT07110714Recruiting
Kneipp water therapy for post-COVID recovery
This study tests if Kneipp hydrotherapy (a gentle water therapy) can help improve symptoms in people with Post-COVID Syndrome. You will use a smartphone app to track your heart rate and answer questionnaires.
Füssen, BavariaAges 18 years+ - NCT07123727RecruitingPhase 2
Testing Anktiva for long COVID symptoms
This study tests if the drug Anktiva can help people with long COVID. To join, you must have had at least one confirmed COVID-19 infection and now have lasting symptoms that started or got worse after that infection.
El Segundo, CaliforniaAges 18–70 - NCT07140094Recruiting
Long COVID Relief Through Learning Mindfulness
This study tests whether a mindfulness program can help ease long COVID symptoms. You will learn simple mindfulness techniques and see if they improve your daily life.
New York, New YorkAges 18 years+ - NCT07189936RecruitingPhase 2
Testing 2-HOBA for Immune Issues in Long COVID with POTS
This trial tests if a medication called 2-HOBA can help with ongoing immune system issues in people with Long COVID who also have POTS. It aims to reduce fatigue and other symptoms by calming overactive immune responses.
Nashville, TennesseeAges 18 years+
Hear when a new Long COVID Syndrome trial opens
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Common questions
- Are there clinical trials for long covid syndrome?
- Yes. Clin2 currently lists 50 recruiting long covid syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a long covid syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a long covid syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.