Clinical trials
Cystic Fibrosis Pulmonary Exacerbation clinical trials
Below are recruiting cystic fibrosis pulmonary exacerbation clinical trials, each written for real people, not researchers. We’re tracking 46 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04530383RecruitingPhase 2
Metformin add-on for adult cystic-fibrosis related diabetes on CF meds
This trial tests whether adding metformin can improve blood-sugar control and related lung cell function in adults who have cystic-fibrosis–related diabetes (CFRD) and are already taking CFTR modulator therapy. It may help if your diabetes is still not well controlled despite those CF medicines.
Kansas City, KansasAges 18 years+ - NCT04731272RecruitingPhase 2
Weekly GLP-1 medicine for blood sugar issues in adults with CF
This Phase 2 trial tests a weekly GLP-1 medicine (dulaglutide) to improve blood sugar control in adults with cystic fibrosis (CF) who have trouble managing glucose. It may help people with CF-related prediabetes or diabetes by improving how their body handles sugar.
Aurora, ColoradoAges 18 years+ - NCT07048262RecruitingPhase 2
Study of an inhaled drug for adults with non-CF bronchiectasis
This trial tests an inhaled medication called CSL787 to see if it can help people with non-cystic fibrosis bronchiectasis (a lung condition that causes frequent infections and breathing problems). The study looks at different doses and checks how well the drug works and if it is safe.
QueenslandAges 18–85 - NCT02740868RecruitingPhase 2
Breathing MRI using xenon gas to study lungs
This trial uses a special breathing MRI (you breathe a gas mixture) to measure how well your lungs work. It studies healthy kids and people with lung conditions like cystic fibrosis or asthma, and it may help researchers better understand lung function and flare-ups.
Toronto, OntarioAges 8 years+ - NCT07599839Recruiting
Study of bronchiectasis severity and flare-up risk
This study helps doctors understand how severe your bronchiectasis is and predict when you might have flare-ups. You'll have routine tests over 12 months to help researchers learn more about this condition and improve future care.
Asyut, Asyut EgyptAges 18 years+ - NCT07275905RecruitingPhase 1
Phage therapy for chronic achromobacter lung infection in cystic fibrosis
This study tests whether giving you a mixture of viruses (called phages) that specifically target the bacteria Achromobacter can help treat your chronic lung infection. You would breathe in the phages, and the study will check if this is safe and helps improve your breathing.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06595420Recruiting
Kidney health in people with cystic fibrosis on new treatments
This study looks at how the kidneys work in people with cystic fibrosis, especially those taking highly effective new treatments. It aims to understand kidney function in different groups, including those who are hospitalized frequently or rarely.
Birmingham, AlabamaAges 7 years+ - NCT07608328RecruitingPhase 4
Azithromycin to Reduce Bronchiectasis Flare-Ups
This study tests whether a common antibiotic called azithromycin can help prevent flare-ups (sudden worsening) of bronchiectasis—a lung condition where airways become permanently enlarged and damaged. Patients will take azithromycin or a placebo for 12 months to see if it reduces how often they get sick.
AsyutAges 18 years+ - NCT06996951RecruitingPhase 3
Sinus treatments in cystic fibrosis with modern modulator therapy
This study looks at how different sinus treatments affect people with cystic fibrosis who are taking modern modulator therapy. It aims to understand which rinses work best for chronic sinus problems.
Indianapolis, IndianaAges 18 years+ - NCT06603246RecruitingPhase 1
Study of inhaled GDC-6988 for mucus lung diseases
This study tests an inhaled medicine (GDC-6988) to see if it is safe and helps clear mucus from the lungs in people with mucus-related lung diseases like chronic bronchitis, COPD, or bronchiectasis. You may qualify if your lung function is fairly stable and you produce daily mucus.
Birmingham, AlabamaAges 18 years+ - NCT05860803Recruiting
Breathing training plus exercise to improve breathing capacity
This study looks at whether breathing exercises combined with exercise training can improve how much and how well you can breathe during activity in people with non-cystic fibrosis bronchiectasis. It may help by improving breathing efficiency and exercise tolerance, but you must be stable and healthy enough to safely exercise.
Jacksonville, FloridaAges 21–80 - NCT07599969Recruiting
Understanding bronchiectasis subtypes for better treatment
This study helps doctors identify different types of bronchiectasis (a lung disease where airways are permanently widened and damaged) to better understand how the disease develops and progresses. By following patients over time and collecting medical information, researchers hope to create a system that predicts which patients will worsen and need different treatments.
Asyut, Assiut EgyptAges 18 years+ - NCT07112235Recruiting
COPD and cold virus study
This study looks at how the common cold virus affects people with COPD to find new treatments. If you have moderate COPD and your symptoms flare up when you catch a cold, you may be able to help.
LondonAges 40–75 - NCT07805174Recruiting
High-intensity interval exercise for bronchiectasis
This study tests whether high-intensity interval exercise (short bursts of vigorous activity) is safe and helpful for people with bronchiectasis, a chronic lung condition. If you join, you will do supervised exercise sessions to see if it improves your fitness and quality of life.
Ankara, KeçiörenAges 18 years+ - NCT07071324Recruiting
CF Wellness Program for Fatigue
This wellness program tests if coaching sessions can help people with cystic fibrosis who feel tired. It is a remote program you can join using your phone or computer, as long as you get CF care at a participating center.
Denver, ColoradoAges 18 years+ - NCT06926881Recruiting
Home treatment with oscillatory lung expansion for bronchiectasis
This trial tests a home-use device called BiWaze Clear, which helps clear mucus from your lungs. It is for people with bronchiectasis (including those with cystic fibrosis) who have had recent lung infections and can use the device at home.
New Haven, ConnecticutAges 5 years+ - NCT06242795RecruitingPhase 4
Hypertonic saline for non-cystic fibrosis bronchiectasis
This trial tests whether inhaling a saltwater solution (hypertonic saline) twice a day for 12 weeks can help people with bronchiectasis who have a chronic cough and have had flare-ups in the past. It aims to see if this treatment reduces mucus and improves quality of life.
Chapel Hill, North CarolinaAges 18 years+ - NCT04294043RecruitingPhase 1
Gallium IV study for adults with cystic fibrosis and NTM lung infection
This Phase 1 study tests whether an IV medicine called gallium can treat hard-to-treat lung infections (NTM) in adults with cystic fibrosis. It is mainly for people who have not been treated yet for NTM or who have NTM that has not cleared despite antibiotics.
Birmingham, AlabamaAges 18 years+ - NCT05704036RecruitingPhase 4
Estrogen use and bone health in women with cystic fibrosis
This observational study looks at how taking (or not taking) estrogen affects bone health in women with cystic fibrosis (CF). If you may have low estrogen, it also explores whether estrogen levels and symptoms relate to bone density over time.
Baltimore, MarylandAges birth–100 years - NCT03587961RecruitingEarly Phase 1
Personalized testing to find the best CF medicine for you
This early study tests an individualized approach (“theratyping”) to match your cystic fibrosis (CF) to the CFTR medicine that may work best for your specific genetic change. It may help find a more tailored treatment plan and see how your body responds, while using medicines that are already approved for some people with CF.
Birmingham, AlabamaAges 6 years+ - NCT06419062Enrolling by invitation
Using wearables to monitor COPD at home
This study tests if a wearable device can help track your COPD symptoms between doctor visits. You'll use a smartphone or computer to share data, which may help your care team stay on top of your health.
GlasgowAges 18 years+ - NCT06419036Enrolling by invitation
Using medical devices to monitor COPD at home
This study tests whether wearable medical devices can help monitor your COPD symptoms at home. You will use a smartphone app and a small chest patch to track your breathing, which may help you and your doctor better manage your condition.
GlasgowAges 18 years+
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Common questions
- Are there clinical trials for cystic fibrosis pulmonary exacerbation?
- Yes. Clin2 currently lists 46 recruiting cystic fibrosis pulmonary exacerbation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cystic fibrosis pulmonary exacerbation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cystic fibrosis pulmonary exacerbation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.