Clinical trials · Minnesota
Dementia clinical trials in Minnesota
We’re tracking 16 recruiting dementia studies with a site in Minnesota — including Phase 2 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies in Minnesota
- NCT04786223Enrolling by invitationPhase 2
Testing an anti-inflammatory PET imaging treatment in memory loss
This Phase 2 study tests whether targeting “neuroinflammation” (inflammation in the brain) can help in Alzheimer’s disease and related memory disorders. You may help researchers by doing several brain scans (including a special PET/CT scan) along with MRI and amyloid imaging to understand what’s happening in the brain.
Rochester, MinnesotaAges 60 years+ - NCT00950430Enrolling by invitationPhase 4
Brain scan study for amyloid plaques in adults
This study uses brain imaging to look for amyloid plaques (abnormal protein deposits) as people age. It may help researchers better understand how these changes develop over time.
Rochester, MinnesotaAges 30–100 - NCT04363684Recruiting
Study of frontotemporal dementia and related syndromes over time
This study follows people with frontotemporal dementia (FTLD) and related conditions, and collects health and (for some people) body fluid information, to understand how these illnesses change over time. It may help researchers track disease signs and find better ways to measure progression.
Rochester, MinnesotaAges 18 years+ - NCT04171323Recruiting
Active mind training to improve thinking and delay dementia
This study tests an “active mind” computer-based program to help improve thinking skills and possibly slow the process toward dementia. You may be randomly assigned to different program options to see which approach works best for your goals.
Minneapolis, MinnesotaAges 55–89 - NCT05826457Enrolling by invitation
Study for early RBD as a possible Parkinson’s risk
This study looks at people with REM sleep behavior disorder (RBD), confirmed by a sleep test, who may be in the early “prodromal” stage before Parkinson’s or related diseases. It also enrolls healthy controls to compare results from brain and body testing to better understand who is at risk.
Rochester, MinnesotaAges 18 years+ - NCT04680130Enrolling by invitation
Study of brain, genetics, and clinical symptoms in neurodegenerative illness
This study looks at how your symptoms, brain imaging (MRI), and genetic factors relate to neurodegenerative conditions. It may help researchers better understand what causes these illnesses and how to classify them.
Rochester, MinnesotaAges 21 years+ - NCT05617014Enrolling by invitation
ADNI4 study for early Alzheimer’s with brain imaging tests
This study enrolls people with no memory impairment, mild memory problems, or mild Alzheimer’s dementia to test how brain scans and cognitive tests relate to Alzheimer’s disease. It may help by contributing to better early diagnosis and by letting you see whether you fit into the study’s imaging and blood-test pathway.
Rochester, MinnesotaAges 55–90 - NCT05514106Enrolling by invitationPhase 4
MIBG heart scan study for aging and neurologic conditions
This Phase 4 study tests how an iodine-based heart scan (a special imaging test) works in people with certain neurologic diagnoses and aging-related conditions. It may help researchers better understand the heart-brain connection in these disorders and improve future care.
Rochester, MinnesotaAges 40–90 - NCT03489278Recruiting
Support procedures study for ALS using electronic health records
This study is about improving the research process for people with ALS by using electronic health records from participating clinics. If you have ALS and receive care at an Epic-using center, you may be asked to help with consent and study procedures.
Minneapolis, MinnesotaAges 18 years+ - NCT04262206RecruitingPhase 4
Testing how statins affect outcomes in adults 75 and older
This trial studies whether cholesterol-lowering medicine (a statin, specifically atorvastatin) improves health and benefits in people age 75 and older in everyday life. It may help doctors understand which older adults benefit most and how to use these medicines safely.
Minneapolis, MinnesotaAges 75 years+ - NCT04916210Recruiting
Study how stroke type affects thinking and recovery
This study looks at what predicts memory and thinking problems after different types of stroke or brain bleeding, and how blood-vessel changes relate to recovery. You may be invited if you recently had a stroke/bleed and can complete a baseline check within 6 weeks.
Minneapolis, MinnesotaAges 18 years+ - NCT01799915Recruiting
Study of causes and progression of synuclein-related nerve conditions
This study follows people over time to better understand “synucleinopathies,” which are conditions that affect the nervous system as it develops and progresses. You may be asked to return for visits and report symptoms, especially those that happen when you stand up.
Rochester, MinnesotaAges 18 years+ - NCT01453127Enrolling by invitationPhase 4
DaTscan scan for aging and movement brain conditions
This trial uses a special brain scan called DaTscan to study how certain brain conditions change with aging and over time. It may help researchers better understand movement and other neurodegenerative conditions and who may benefit from future treatments.
Rochester, MinnesotaAges 40–90 - NCT07546708Recruiting
Understanding Dementia Care in Black Immigrant Communities
This study explores how dementia (memory loss) affects Black immigrant families and their caregivers. Researchers want to learn about challenges and support needs to improve care and services for Black immigrant communities.
Minneapolis, MinnesotaAges 18 years+ - NCT06723015Enrolling by invitationPhase 2
Tau PET in anti-amyloid therapy for Alzheimer's
This study uses brain scans to see how anti-amyloid treatments affect tau protein buildup in people with early Alzheimer's. If you have mild cognitive impairment or mild Alzheimer's, you may be eligible to help understand how these treatments work.
Rochester, MinnesotaAges 50–90 - NCT03623672Enrolling by invitation
Study for early signs of Parkinson-related brain changes
This study enrolls people with idiopathic REM sleep behavior disorder, a sleep problem that can come before Parkinson’s disease or related conditions. It aims to better understand early (“prodromal”) changes so future treatments can be targeted earlier.
Minneapolis, MinnesotaAges 18 years+
Dementia trials by city in Minnesota
Where these studies are running in Minnesota
Institutions with a site for the recruiting dementia studies listed above.
- Mayo Clinic · 13 studies
- University of Minnesota · 5 studies
- Allina Health Cancer Institute
- Essentia Health Cancer Center
- Hennepin County Medical Center
- Minneapolis VA Health Care System
What taking part in a dementia study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Dementia trials in other states
Common questions
- Are there dementia clinical trials in Minnesota?
- Yes. We're currently tracking 16 recruiting dementia studies with a site in Minnesota, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a dementia study in Minnesota?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Minnesota to take part?
- Not necessarily. These studies have a site in Minnesota, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a dementia trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New dementia studies open in Minnesota regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.