Clinical trials
Depressed clinical trials
Below are recruiting depressed clinical trials, each written for real people, not researchers. We’re tracking 1,500 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07168096Recruiting
Emotional health and decision-making in cancer patients
This study tracks how anxiety and depression change over time in people with solid tumors. It aims to find risk factors and improve supportive care, while also exploring how much patients understand about their prognosis and want to be involved in decisions.
Santander, CantabriaAges 18 years+ - NCT07174947RecruitingPhase 2
Fluoxetine plus immunotherapy for advanced liver cancer with depression
This study tests whether adding the antidepressant fluoxetine (Prozac) to standard immunotherapy can help treat advanced liver or bile duct cancer in people who also have depression or anxiety. You must not have received any prior cancer treatment and be ready to start immunotherapy as your first therapy.
Wenzhou, ZhejiangAges 18–80 - NCT07180342Recruiting
Nature outings for depression recovery
This study tests whether nature-based group trips can help people with major depression feel better. You would visit parks and do outdoor activities while researchers measure changes in mood and daily function.
Jinan, ShandongAges 18–59 - NCT07182890RecruitingPhase 4
Probiotic for anxiety and depression in functional dyspepsia
This trial tests whether a probiotic called Clostridium Butyricum can help reduce anxiety and depression in people with functional dyspepsia (a type of stomach discomfort without a clear cause). If you have mild to moderate anxiety or depression along with your stomach symptoms, this study may offer a potential new treatment option.
Xi’an, ShanxiAges 18–80 - NCT07183748RecruitingPhase 2
Psilocybin microdosing plus therapy for hard-to-treat depression
This trial tests whether taking very small, repeated doses of psilocybin (a substance found in magic mushrooms) along with talk therapy can help people with depression that hasn't gotten better with other treatments. You'll need to stop your current depression medications and avoid drugs or alcohol for the study period.
BeershebaAges 18–65 - NCT07186309Recruiting
At-home test for postpartum depression study
This trial is testing a way to screen for postpartum depression from the comfort of your home. You would take a test during pregnancy to see if it can help find women who may be at risk.
Charlottesville, VirginiaAges 18 years+ - NCT07187492RecruitingPhase 4
Can a probiotic ease anxiety and depression in functional dyspepsia?
This trial tests whether a probiotic called Bacillus coagulans can help reduce anxiety and depression in people with functional dyspepsia, a condition that causes stomach pain or discomfort without a clear physical cause. You may qualify if you have mild to moderate anxiety or depression alongside your stomach symptoms.
Xi’an, ShanxiAges 18–80 - NCT07191392Recruiting
Brain stimulation for depression using focused electric fields
This trial tests whether temporal interference stimulation (a noninvasive brain stimulation method) can improve symptoms of depression. It focuses on people who are currently experiencing moderate to severe depression.
Hefei, AnhuiAges 12–60 - NCT07193901RecruitingPhase 2
Nasal spray for depression with suicidal thoughts
This trial tests an experimental nasal spray for people with major depression who are currently having suicidal thoughts. It aims to see if the spray can quickly reduce depression and suicidal feelings.
BeijingAges 18–64 - NCT07197138Recruiting
TMS for depression with long COVID
This trial tests whether accelerated TMS (a brain stimulation treatment) can help people with depression who also have long COVID. It may be an option if your depression hasn't improved enough with medication alone.
Munich, BavariaAges 18–65 - NCT07201480Recruiting
Thinking about death and emotions: a lab study
This study looks at how thinking about death affects feelings of anxiety and sadness. You'll do a short lab task and answer questions.
Cluj-NapocaAges 18–65 - NCT07204314RecruitingPhase 3
Study of vortioxetine for teens with depression in Japan
This trial tests whether vortioxetine helps reduce symptoms of major depression in Japanese teenagers aged 12-17. It compares the study drug to a placebo to see if it is safe and effective.
Nagoya, Aichi-kenAges 12–17 - NCT07210255Recruiting
SAINT TMS for postpartum depression
This trial tests a special type of TMS (brain stimulation) called SAINT for severe depression that started around childbirth. It may help new mothers who are still within a year postpartum and have not found relief from other treatments.
Worcester, MassachusettsAges 18–45 - NCT07212465Recruiting
Brain stimulation for depression in older adults
This study tests a new, faster brain stimulation method for depression in adults aged 60-85 who haven't improved with medication. The treatment targets a part of the brain linked to mood and may offer relief for those who have not found other treatments effective.
Toronto, OntarioAges 60–85 - NCT07216326Recruiting
Depression help for Black and Latinx youth
This trial tests a program to help Black and Latinx teens and young adults with depression. It involves in-person sessions to learn coping skills and support.
Chicago, IllinoisAges 15–20 - NCT07216404RecruitingPhase 2
Psilocybin therapy for depression in lung cancer patients
This trial tests whether a psychedelic-assisted therapy can help treat major depression in people with non-small cell lung cancer. If you have moderate to severe depression and are receiving cancer treatment, you may be able to join.
Columbus, OhioAges 18 years+ - NCT07217444Recruiting
Deep TMS for depression in teens
This trial tests whether a non-invasive brain stimulation technique called deep transcranial magnetic stimulation (dTMS) can help teens with moderate to severe depression feel better. It involves wearing a special magnetic coil on the head during several sessions.
Cincinnati, OhioAges 14–18 - NCT07221929Recruiting
Exercise plus CBT for depression: The CBT+ Trial
This study tests whether adding exercise before standard talk therapy (CBT) helps treat depression more effectively than CBT alone. You will be asked to do moderate exercise and then receive CBT sessions over 8 weeks.
Madison, WisconsinAges 18–65 - NCT07226661RecruitingPhase 2
Study of an investigational drug for depression
This trial tests an investigational medication for adults with major depressive disorder who are currently taking an antidepressant but still have symptoms. It aims to see if adding this new drug can improve mood better than a placebo.
Garden Grove, CaliforniaAges 18–70 - NCT07228468Recruiting
Home brain stimulation for depression
This trial tests if a gentle electrical current applied to the head at home can help reduce symptoms of major depression. You would use a device for short sessions over several weeks, while continuing your usual care.
CardiffAges 18 years+ - NCT07230990Recruiting
Brain Stimulation Study for Depression
This study uses a special type of brain stimulation (rTMS, which uses magnetic pulses) to treat depression. It focuses on part of the brain called the orbitofrontal cortex and aims to understand how stimulating it helps improve mood.
Boston, MassachusettsAges 18–65 - NCT07241325Recruiting
Emotional health and quality of life in type 2 diabetes
This study looks at how adults with type 2 diabetes feel emotionally and mentally, and how their health affects their daily life. Participants will fill out questionnaires about their mood, well-being, and quality of life.
TaipeiAges 18 years+ - NCT07242105Recruiting
Improving brain activity in depression
This study tests if a type of brain stimulation (TMS) can improve brain function in people with depression. It also includes a small group of epilepsy patients who are already having brain monitoring. The goal is to find new ways to treat depression by targeting specific brain areas.
Iowa City, CaliforniaAges 18–65 - NCT07247344Recruiting
Depression in hospitalized teens: a brain study
This study looks at brain and behavior in teens aged 10–20 who are hospitalized for depression or bipolar disorder. It aims to better understand the condition and may help guide future treatments.
Nanjing, JiangsuAges 10–20
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Common questions
- Are there clinical trials for depressed?
- Yes. Clin2 currently lists 1,500 recruiting depressed studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a depressed trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a depressed trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.